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[Rewarming of humans in deep hypothermia using a short-wave therapy apparatus. Report of 3 cases].

Three cases of successful "rewarming" of low hypothermic patients (below 30 degrees C = 86 degrees F) with a short-wave therapy apparatus (operating frequency 27.12 MHz) and eddy-current electrodes (Diplode) are described. The patients survived without any visible complications such as afterdrop, ventricular fibrillation or burns. This method is simple and not restricted to special hospitals.

Adult↗

Postoperative hypothermia in adults: relationship of age, anesthesia, and shivering to rewarming.

Frequency, magnitude, and duration of hypothermia (core body temperature less than 36.0 C) in the recovery room (RR) were determined in 198 adults. In addition, the influence of age, anesthetic technique, and shivering on the rewarming process was assessed. Tympanic membrane temperatures were recorded on admission to the RR and every 15 minutes thereafter until discharge from the RR. Sixty percent of the subjects had temperatures less than 36.0 C on admission to the RR. Elderly subjects (greater than or equal to 60 yr) had lower RR admission and discharge temperatures and experienced longer duration of hypothermia than did younger patients. General anesthesia was associated with a significantly more rapid rate of increase in postoperative temperature and a shorter duration of hypothermia than was regional anesthesia. The incidence of shivering and the incidence of hypothermia were significantly related 30 and 45 minutes after admission to the RR. Duration of hypothermia varied with different operative procedures.

Adolescent↗

Hand immersion as a method of cooling and rewarming: a short review.

Many cooling and warming procedures have been proposed for the treatment of hyperthermic or hypothermic individuals. One of the most recent of these is the use of hand immersion as a simple method to gain or lose heat. In the present paper the principles underlying this approach, and the evidence for and against hand rewarming/cooling, are briefly reviewed. It is concluded that hand immersion is likely to be more effective for cooling than rewarming individuals.

Cold Temperature↗

Membrane integrity and development of immature murine cumulus-oocyte complexes following slow cooling to -60 degrees C: the effect of immediate rewarming, plunging into LN2 and two-controlled-rate-stage cooling.

Cryopreservation of murine germinal vesicle (GV) stage cumulus-oocyte complexes (COCs) has been shown to result in poor development and cumulus cell damage. In an attempt to determine the stage of the cryopreservation protocol at which damage occurs, three cooling profiles were compared: slow-cooling (0.3 degrees C/min) to -60 degrees C (protocol A); slow-cooling to -60 degrees C and plunging to -196 degrees C (protocol B); or slow-cooling to -60 degrees C followed by further cooling at 10 degrees C/min to -150 degrees C, then plunging to -196 degrees C (protocol C). GV-stage COCs were collected from hormone-primed mice by repeated puncturing of ovarian follicles. COCs were exposed to 1.5 M Me(2)SO prior to cooling to -60 or -196 degrees C. Membrane integrity was assessed immediately after thawing using carboxy fluorescein and propidium iodide. A greater proportion of cumulus cells were damaged following protocol B than protocol A. Damage was less extensive following protocol C than following protocol B. For assessment of development, COCs were matured and fertilised in vitro. Morphological normality was significantly reduced following cooling to -60 or -196 degrees C compared with non-cryopreserved controls. Fertilisation of oocytes assessed as normal post-treatment was not significantly different between any of the groups. Development to blastocyst was least from oocytes exposed to protocol B, being significantly worse than for oocytes exposed to protocol A, but not significantly different to protocol C. A protocol comprising two stages of controlled-rate cooling decreased damage to the membranes of cumulus cells but did not significantly improve embryo development.

Animals↗

Development of a single mode electromagnetic resonant cavity for rewarming of cryopreserved biomaterials.

An electromagnetic (EM) heating system is developed to achieve the rapid and uniform warming of cryopreserved biomaterials. Using the heating system, a rectangular resonant cavity is excited in TE101 mode at frequencies near 434 MHz. In experiments, a spherical phantom of biomaterial with a diameter of 36 mm is placed at the center of the cavity. The phantom is first cooled down to about -80 degrees C within the cavity and then thawed by EM absorption. Results show that EM warming can produce much higher warming rate than conventional water-bath warming method. The spatial temperature distribution in the phantom during EM warming is also more uniform than that during the water-bath warming.

Adhesives↗

Effectiveness of a circulating-water warming garment in rewarming after pediatric cardiac surgery using hypothermic cardiopulmonary bypass.

OBJECTIVE: To evaluate the effectiveness and safety of the ALLON 2001 microprocessor-based thermoregulation system in pediatric patients undergoing cardiac surgery requiring hypothermic cardiopulmonary bypass compared with the routine thermal care. DESIGN: Prospective randomized clinical study. SETTING: Single tertiary academic medical center. PARTICIPANTS: Infants (0-1 year) who underwent congenital heart surgery requiring hypothermic cardiopulmonary bypass (n = 18). Patients with open wounds and/or patients treated with an investigational drug or device within 30 days of surgery were excluded. INTERVENTIONS: Randomized use of thermoregulation system (warming garment, n = 9) or routine thermal care (control, n = 9) after separating from cardiopulmonary bypass until the arrival to the pediatric intensive care unit (PICU). MEASUREMENTS AND MAIN RESULTS: There were no statistically significant differences in the demographic data, cardiopulmonary bypass time, operating room time, incidence of deep hypothermic circulatory arrest, and cooling temperature between the groups. The nasopharyngeal temperature was significantly higher in the warming garment group after separation from cardiopulmonary bypass. Nasopharyngeal temperature at 20 minutes was 36.5 degrees C versus 35.01 degrees C (p = 0.0047), at 40 minutes was 36.98 degrees C versus 35.30 degrees C (p = 0.034), and at admission to the PICU was 36.09 degrees C versus 35.31 degrees C (p = not significant). There was no difference in the core-to-peripheral temperature gradient (nasopharyngeal-to-skin temperature) between the 2 study groups at any time point. No adverse events related to the use of the warming garment thermoregulation system were observed. CONCLUSION: The investigated thermoregulation system was effective in preventing the after-drop of temperature that occurs after cardiopulmonary bypass in small infants compared with routine warming methods.

Body Temperature↗