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Results for “Multiphasic Screening”

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PubMed1975

An evaluation of the IFA-GC procedure in a low risk population.

An automated indirect fluorescent antibody (IFA) test for gonococcal antibody was evaluated in 600 low risk females; 392 were prenatal patients from public and private clinics and 208 were apparently healthy females state employees in a multiphasic screening program. Clinical histories, physical examinations, and cervical cultures were obtained on all patients. The results of the cultures and serologic test were compared. Although the number of culture positive patients in the study was low, the lack of sensitivity of the IFA test in detecting gonococcal infection in these patients was disturbing. This observation and the number of apparent false positive IFA tests lead us to conclude that the automated IFA test for detection of gonorrhea shows promise, but we could not consider adopting the test in its present stage of development.

Antibodies↗
PubMed2006

Secondary healthcare contacts after multiphasic preventive health screening: a randomized trial.

AIM: To analyze the consequence of preventive health screenings and discussions on the utilization of secondary healthcare. METHODS: All 30- to 49-year-old residents registered with a general practitioner in the district of Ebeltoft, Denmark, were included (n = 3,464) in a randomized controlled trial with eight years' follow-up. A random sample of 2,030 subjects was selected for invitation (Invited). The remaining 1,434 persons were never contacted and served as external control group (Non-Invited). Persons accepting participation were randomly divided into one internal control group (Questionnaire) and two intervention groups. One intervention group was offered three health screenings (Health Screening) during the five years. The other intervention group were in addition offered a yearly health discussion with their general practitioner (Health Screening and Discussion). RESULTS: The rate ratio for hospital admissions was 0.97 (95% confidence interval 0.80 to 1.18) in the Invited group compared with the Non-Invited. The annual admission rates showed a significant trend (p = 0.0003) with a decrease four and five years after intervention launch for the Invited group compared with the Non-Invited. A similar trend was found when comparing the internal control group with intervention groups (p = 0.0016). CONCLUSIONS: A 30- to 49-year-old general population's utilization of secondary healthcare did not increase in response to a general health promotion offer. During the observation period a significant decline in annual hospital admission rates was seen.

Adult↗
PubMed1998

Are health surveys among elderly people worthwhile? The Albertina Project.

OBJECTIVE: To study the need for health screening among elderly people. SETTING, DESIGN AND SUBJECTS: A random sample of 605 people 75 years or older from the general population of Uppsala, Sweden received a postal questionnaire on health issues, and a random subsample of 101 persons were offered a health survey. MAIN OUTCOME MEASURES: Symptoms and signs of disease in questionnaire or at health examination. RESULTS: Thirty-nine people came to the health examination at the primary health care centre (PHCC), 15 were examined in their homes, and 11 were interviewed by telephone. Seventy-eight findings were made in the PHCC group, out of which 60 were known by the proband and 18 were new. In ten cases some action was taken. Of the 54 people examined, 50 persons had one or several findings. The most prevalent problems were hypertension, urinary incontinence, and hearing problems. However, few of these problems warranted referral to a general practitioner or hospital. CONCLUSIONS: It appears that a health survey of elderly people yielded little new information on the state of health among those surveyed at the time of the data collection. The bearing on the present-day situation is discussed.

Aged↗
PubMed1972

Mass screening.

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Humans↗
PubMed1976

Familial risk and cancer control.

An intensive study of the family history of cancer in 4,515 patients screened consecutively by a multiphasic mobile cancer detection unit showed, after age correction, that cancer had developed in 8.9% of the probands when there was one cancer in a single first-degree relative, 16.2% had cancer with two family members affected, and 27.4% had cancer when three or more family members had been affected. This constituted a significant correlation between family and personal histories of cancer in these patients. Extrapolation to the United States population with cancer-control implications are given.

Age Factors↗
PubMed2002

Hemochromatosis detection in a health screening program at an Alabama forest products mill.

We analyzed hemochromatosis detection in a 11.5-year multiphasic health screening program at a forest products mill. There were 2199 participants: 2032 Whites (1506 men, 526 women) and 167 African Americans (124 men, 43 women); 85.0% of employees were screened. Iron and transferrin saturation were measured in a serum biochemistry profile on specimens obtained after overnight fasting; ferritin was measured in participants with elevated iron concentrations or transferrin saturation > 48%. Participants with elevated ferritin levels underwent further evaluation. Eight White men were diagnosed to have hemochromatosis (frequency 0.0039 in Whites, 0.0053 in White men). The estimated cost per case detected was $8826. Family members of two participants with hemochromatosis were also diagnosed to have hemochromatosis or iron overload. We conclude that detecting hemochromatosis in a workplace multiphasic health screening program is efficacious and economical.

Adult↗
PubMed1968

Health screening.

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Chronic Disease↗
PubMed1985

A demonstration project on cancer screening in rural Thailand: preliminary report.

A demonstration multiphasic cancer screening program was conducted in a rural village in Thailand under the coordination of Bangkok's National Cancer Institute. The village's physician, mayor, and other members of the community assumed a variety of volunteer roles in order to provide logistical support. In short, this became a community-oriented program. 349 patients (100 males, 249 females) were evaluated. 6 verified cancers (2 recurrent) were detected. 47 patients received a diagnosis of a putative precancer disease, such as dysplasia of the uterine cervix, leukoplakia of the vulva, or of the oral mucosa. Cancer educational programs were provided for the entire community and more intensively for those patients who participated in the program. The most vexing problem was poor follow-up.

Adult↗
PubMed2004

[The PreFord Study. A prospective cohort study to evaluate the risk of a cardiovascular event (overall-collective) as well as a prospective, randomized, controlled, multicentre clinical intervention study (high-risk-collective) on primary prevention of cardiovascular diseases in the Ford Motor Company employees in Germany].

The PreFord Study is a multicenter prospective cohort study to evaluate guideline based risk management on primary prevention of cardiovascular diseases. Furthermore a randomised controlled trial (RCT) will be designed to analyse the effect of a special intervention program. 40,000 employees of the Ford Motor Company, Visteon Company and Deutz Company in Germany will be included, monitored for ten years and the following primary endpoints will be investigated: 1. evaluation and comparison of established and newly developed risk-scores, 2. the relative impact of single and combined cardiovascular risk factors on cardiovascular diseases, 3. the influence of a novel occupationally integrated ambulant rehabilitation program in combination with a guideline oriented optimal drug therapy within a high risk group on the primary endpoint: risk reduction by, 4. the influence of this intervention on secondary endpoints: death, myocardial infarction and stroke, combined appearance of angina pectoris and hospitalisation, occurrence of cerebral circulatory disorder and hospitalisation, occurrence of peripheral occlusive arterial disease and hospitalisation and single cardiovascular risk factors and cost-benefit-analysis. Beginning with an cross sectional study there will be a systemic screening of cardiovascular risk profiles, of anthropometric data and different lifestyle-factors. Based on these data participants will be differentiated into three risk-groups according to the risk score of the European Society of Cardiology (risk of a lethal primary acute cardiovascular event: I < or = 1%; II > 1-< 5% and III > or = 5%). In the following longitudinal study different strategies will be applied: Group I: low risk (< 0.5% per year): repetition of the investigation after five and ten years. Group II: middle risk, (0.6% to 1.4% per year), repetition of the investigation every two years, instruction of the patients general practitioner (GP) with respect to a risk factor oriented and evidence based treatment. Group III: high risk, (> 1.5% per year or >15% within the next 10 years) will be randomised into two interventional groups. The first one, the intervention-group "PreFord" will perform an occupational integrated rehabilitation program (2,5-3 hours twice a week, for 15 weeks according to the BAR guidelines) with a following engagement in heart-groups and an annual repetition of the check-ups. The second group, the "classic" intervention-group will be treated evidence based in cooperation with their GP. As a result of this long term interventional study efficient, area wide implementable and economically feasible prevention concepts with special regards to operational healthcare will be developed and evaluated. Core elements will be exercise- and lifestyle-oriented concepts as well as guideline-based pharmacotherapy.

Adult↗