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Results for “Lactation Disorders”

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At least 361 records · Page 20Linked to original sources
PubMed1987

[Effect of hysterectomy in swine on health status and various indicators of peripheral blood. I. Clinical observations].

Studies were carried out on 36 sows from 100-250 kg of body weight, divided into 5 groups. The sows of group I were given Stresnil and Vetbutal to examine the effect of the anesthetics used during operation on the health condition of the animals studied in the other groups. Laparotomy was performed in group II, amputation of unpregnant uterus in group III, amputation of pregnant uterus or several hours after delivery in group IV, and amputation of pathologically changed uterus by the intraabdominal method and of fallen out uterus after delivery by the extra-abdominal method in group V. It was found that laparotomy, amputation of unpregnant uterus and that several hours after delivery were not a serious danger to the life of pigs, but general disturbances occurring after the operation depended on the magnitude of the operational trauma and health condition before operation. The treatment of pathologically changed uterus by intraabdominal amputation gave positive results in 69.2% of cases. However, no positive results were obtained in the treatment of fallen out uterus after delivery by extraabdominal amputation.

Animals↗
PubMed2003

Age-related changes in cerebral lactate metabolism in sleep-disordered breathing.

Thirty-one patients, aged 22-71 years, with nocturnal apneic episodes and/or habitual snoring were studied with magnetic resonance spectroscopy (MRS) and diagnostic polysomnography separately to determine whether accumulation of lactate caused by cerebral hypoxia during sleep is associated with sleep-disordered breathing (SDB), aging and co-morbidities related to SDB. Eight proton magnetic resonance spectra for sleep and two for periods of arousal were obtained from the right centrum semiovale. All patients were evaluated for the presence or absence of co-morbidities including hypertension, cardiac disease, diabetes mellitus, and hyperlipidemia. Significant lactate signals were found in seven patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) during sleep periods, and none during periods of arousal. Aging was significantly related to the presence or absence of significant lactate signals during sleep periods as determined by logistic regression analysis (beta=0.2480; 95% confidence interval, 0.0905-0.5094; P=0.0001). Apnea index (AI), apnea-hypopnea index (AHI), and minimum value of peripheral oxyhemoglobin saturation each significantly interacted with age (P=0.0081, 0.0284, and 0.0302, respectively). Our findings suggest that SDB combined with aging is related to accumulation of lactate during sleep.

Adult↗
PubMed1999

Choreic movements and MRI abnormalities in the subthalamic nuclei reversible after administration of coenzyme Q10 and multiple vitamins in a patient with bilateral optic neuropathy.

A 37-year-old man developed choreic movements of the limbs over a few months. His medical history included bilateral visual loss detected at the age of 9 and worsening at age 20. Visual field testing showed a central scotoma. Fundus examination showed atrophy of the optic disks and narrowing of vessels. The diagnosis of Leber hereditary optic neuropathy (LHON) was considered. There was no family history of visual loss or movement disorders. Blood lactate:pyruvate ratio was moderately elevated. Skeletal muscle biopsy was normal. Magnetic resonance imaging showed bilateral hypointense lesions on T1-weighted sequences in the subthalamic nuclei and in the lateral part of the substantia nigra. Linear hyperlucencies in the pyramidal tract facing the lateral part of the ruber nuclei were also demonstrated on T2-weighted sequences. Nine LHON-associated mutations were ruled out by RFLP analysis. Treatment with 250 mg coenzyme Q10 per day and multiple vitamins was initiated. Gradual recovery in movement disorders occurred over 1 year. Lactate to pyruvate ratio normalized. No change of visual function was observed. On magnetic resonance imaging performed 3 years later, lesions of the subthalamic nuclei almost completely disappeared. We think the patient might have an unusual, genetically uncharacterized mitochondrial disorder, combining optic neuropathy and chorea.

Adult↗