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Discoloration of a compomer by stains.

This study evaluated the color stability of a polyacid-modified composite (compomer) upon exposure to stains. Five disks were prepared for immersion in each of five stains: coffee, chlorhexidine, cola, red wine, and water as a control. Color measurements were made on a reflection spectrophotometer at baseline, after 24-hour incubation, and after 24, 48, and 72 hour immersion in each stain. At 24 hours, perceptible color changes occurred for specimens in red wine and coffee. After 48 hours, perceptible color changes occurred for specimens in cola. Chlorhexidine and water caused no perceptible color changes. A compomer is susceptible to staining by coffee, red wine, and cola.

Analysis of Variance↗

Absence of smooth motion perception in color vision.

We have tested the behavioral evidence for a separation of the processing of color contrast from motion in the human visual system. Two different aspects of motion perception are examined; the identification of the direction of movement of a chromatic grating and the perception of smooth motion. The results show that color vision is at no great disadvantage in the identification of direction of movement, since this can be done at color contrasts quite close to detection threshold over a wide range of spatial and temporal frequencies. However, we find that subjects can identify direction without having the genuine perception of smooth motion. Smooth motion perception is revealed to be highly impaired since it is detected only at very high color contrasts and over a narrow range of spatial temporal conditions.

Color Perception↗

Color stability of provisional restorative materials after accelerated aging.

PURPOSE: Color of 11 provisional restorative materials (4 acrylic resins and 7 resin composites) was evaluated by reflection spectrophotometry immediately after fabrication, after aging for 15 kJ/m(2), and after aging for 60 kJ/m(2) to determine relative color stability under experimental aging conditions. MATERIALS AND METHODS: Specimens of provisional restorative materials were polymerized according to manufacturers' instructions and aged in an artificial aging chamber with exposure to a total ultraviolet irradiation of 60 kJ/m(2) in increments of 15 kJ/m(2). Color was measured by CIE L*a*b* on a reflection spectrophotometer before and after aging. Color change (Delta E*) was calculated and analyzed statistically by analysis of variance with repeated measures after 15 and 60 kJ/m(2) intervals of aging. RESULTS: Statistically significant changes in color were observed after accelerated aging at both the initial and final aging intervals. Five of the 11 provisional materials tested showed perceptible color change (Delta E* from 3.6 to 9.3) after accelerated aging of 15 kJ/m(2). Seven of the 11 provisional materials tested showed perceptible color change (Delta E* from 3.4 to 9.4) after accelerated aging of 60 kJ/m(2). CONCLUSIONS: Clinically perceptible color changes (Delta E* Delta 3.3) can be expected in some acrylic resin and composite resin provisional materials after accelerated aging.

Acrylic Resins↗

Color vision in epilepsy patients treated with vigabatrin or carbamazepine monotherapy.

PURPOSE: To investigate color vision in epilepsy patients treated with vigabatrin or carbamazepine monotherapy and to evaluate the association between vigabatrin-induced visual field defects and dyschromatopsia. DESIGN: Nonrandomized comparative trial. PARTICIPANTS: Thirty-two epilepsy patients treated with vigabatrin monotherapy, 18 patients treated with carbamazepine monotherapy, and 47 age-matched healthy controls were examined. MAIN OUTCOME MEASURES: Color vision was examined with Standard Pseudoisochromatic Plates 2 (SPP2) screening test, Farnsworth-Munsell 100 (FM 100) hue test, and Color Vision Meter 712 anomaloscope. RESULTS: Abnormal color perception was found in 32% of the epilepsy patients treated with vigabatrin monotherapy and 28% of the epilepsy patients treated with carbamazepine monotherapy. The total error score in the Farnsworth-Munsell 100 hue test was abnormally high in the vigabatrin monotherapy patients who had concentrically constricted visual fields and a statistically significant correlation was found between the temporal visual field extents and the age-adjusted Farnsworth-Munsell 100 total error score in vigabatrin monotherapy patients (R = .533, P = 0.003 in the right eye, R = .563, P = 0.001 in the left eye). Four of 31 (12%) vigabatrin monotherapy patients, and 1 of 18 (6%) carbamazepine monotherapy patients had a blue axis in Farnsworth-Munsell 100 hue test. In the anomaloscope, there were a few pathologic findings in both groups. In the SPP2 screening test, a few plates were not seen in both groups. CONCLUSIONS: Both examined antiepileptic drugs, vigabatrin and carbamazepine, cause acquired color vision defects. The abnormal color perception seems to be associated with constricted visual fields in the vigabatrin monotherapy patients. The duration of carbamazepine therapy correlates with high FM100 total error score. The best method for detecting dyschromatopsia in patients treated with vigabatrin or carbamazepine was the Farnsworth-Munsell 100 hue test. The SPP2 screening test does not seem to be useful in clinical practice.

Adult↗

Preserved color imagery in an achromatopsic.

The loss of color vision secondary to central nervous system disease (achromatopsia) is thought to preclude visual imagery of colors. We report a patient with achromatopsia, secondary to bilateral temporo-occipital infarcts inclusive of the lingual and fusiform gyri, with preserved color imagery. Our findings, in conjunction with previous cases in the literature, are consistent with a single neural network for color processing in which a disconnection of internal activation from stored color representations produces impaired color imagery with preserved color perception, whereas a disconnection of visual input to these representations produces achromatopsia with preserved color imagery.

Cerebral Infarction↗

Monge: The Verriest lecture, Lyon, July 2005.

In 1789, when neither the physical basis of hue nor the retinal basis of color perception was established, the mathematician Gaspard Monte stated firmly that our color perceptions do not depend on the absolute value of the physical variable, but are influenced by the context and in particular by our estimate of the illuminant. He used this insight to explain color contrast effects and the Paradox of Monge (the desaturation of red objects seen through a red filter). He proposed that we can estimate the chromaticity of the illuminant in any scene because all surfaces reflect to us varying mixtures of (i) the body color and (ii) a specular component that represents the illuminant. He also realized that white objects have a special property: Provided that they are illuminated by a single illuminant, such objects exhibit no variation in chromaticity across their surface. Thus at least one of the unique hues exists as an external reference on which observers can agree. It is suggested that other unique hues may also have a basis in the external world.

Aged↗

[Standardized evaluation of red, green and blue perception. Comparison between color arrangement and computer-assisted test procedures].

BACKGROUND: Computerized colortests offer the possibility of determining quantitative color contrast thresholds under standardized conditions. Arrangement tests allow semi-quantitative evaluation of the red, green and blue color sense. To validate the results of a new computerized test, its results are compared to those of arrangement tests. PATIENTS AND METHODS: Thirty-five patients with retinitis pigmentosa (RP, mean age 38.51, +/- 15.14) as well as 30 normal observers (mean age 36.52, +/- 14.33) were evaluated. The computerized color test COLDEF was used, which is a calibrated screen that presents color optotypes on a colored background. All colors are chosen from three-color confusion axes of the CIE-Lu'v' color chart (protan, deutan and tritan axis). By a staircase procedure, the colors of the optotype and background were varied until the observers minimal color contrast threshold is detected. To compare the results of COLDEF with a routine diagnostic tool, the Farnsworth panel D-15 and Lanthony désaturé test were chosen. The results of the arrangement tests were scored by a categorization scheme. RESULTS: Normal observers showed no elevated thresholds either in COLDEF nor in the panel tests. In the RP group increased thresholds along the blue confusion axis could be detected in most cases. Furthermore, COLDEF showed increased thresholds along the red and green axes in some patients. With the computerized test it is always possible to identify the color axis concerned. The new test allows a fast and quantitative assessment of acquired color vision deficiencies.

Adult↗

Molecular patterns of X chromosome-linked color vision genes among 134 men of European ancestry.

We used Southern blot hybridization to study X chromosome-linked color vision genes encoding the apoproteins of red and green visual pigments in 134 unselected Caucasian men. One hundred and thirteen individuals (84.3%) had a normal arrangement of their color vision pigment genes. All had one red pigment gene; the number of green pigment genes ranged from one to five with a mode of two. The frequency of molecular genotypes indicative of normal color vision (84.3%) was significantly lower than had been observed in previous studies of color vision phenotypes. Color vision defects can be due to deletions of red or green pigment genes or due to formation of hybrid genes comprising portions of both red and green pigment genes [Nathans, J., Piantanida, T.P., Eddy, R.L., Shows, T.B., Jr., & Hogness, D.S. (1986) Science 232, 203-210]. Characteristic anomalous patterns were seen in 15 (11.2%) individuals: 7 (5.2%) had patterns characteristic of deuteranomaly (mild defect in green color perception), 2 (1.5%) had patterns characteristic of deuteranopia (severe defect in green color perception), and 6 (4.5%) had protan patterns (the red perception defects protanomaly and protanopia cannot be differentiated by current molecular methods). Previously undescribed hybrid gene patterns consisting of both green and red pigment gene fragments in addition to normal red and green genes were observed in another 6 individuals (4.5%). Only 2 of these patterns were considered as deuteranomalous. Thus, DNA testing detected anomalous color vision pigment genes at a higher frequency than expected from phenotypic color vision tests. Some color vision gene arrays associated with hybrid genes are likely to mediate normal color vision.

Color Perception↗

Accelerated aging affects color stability of provisional restorative materials.

PURPOSE: The color stability of two shades each of five acrylic resin and seven resin composite provisional restorative materials was evaluated by reflection spectrophotometry following in vitro accelerated aging. MATERIALS AND METHODS: Specimens of provisional restorative materials were polymerized according to manufacturers' instructions and aged in an artificial aging chamber with exposure to a total ultraviolet irradiation of 60 kJ/m2. Color was measured by CIE L*a*b* on a reflection spectrophotometer before and after aging. Color change (delta E*) was calculated and analyzed statistically. RESULTS: Statistically significant changes in color were observed after accelerated aging. Nine of the 12 provisional materials tested showed perceptible color change of at least one of the shades tested. The most color-stable materials were the acrylic, Alike, and the resin composites, Luxatemp and Protemp Garant, which had no perceptible color changes under these conditions. CONCLUSIONS: Some acrylic resin and composite provisional materials change color significantly and perceptibly when exposed to in vitro accelerated aging conditions.

Acrylic Resins↗

Testing color discrimination without the use of special stimuli or technical equipment.

Recently a number of self-report inventories have been developed to provide quick, valid, and reliable measures of sensory function without the use of technical equipment. One such measure, the 10-item Color Screening Inventory, was developed to detect individuals with deficient color perception. In the present study we used a sample of 268 subjects who were tested on both the Farnsworth-Munsell 100-hue test and the Color Screening Inventory. Analysis showed that inventory scores also predict continuous variations in and individuals' ability to discriminate colors, with an eta of .69, which explains 48% of the predictive variance. It was possible to describe the data using a quadratic regression equation which has a corrected correlation of .52. Using this, a conversion table was generated to allow rapid estimation of 100-hue test scores from the inventory. On the basis of the results, the Color Screening Inventory appears to be a quick and effective means of testing color discrimination without requiring special stimuli, technical equipment, or controlled testing environments.

Adult↗

Escher in color space: individual-differences multidimensional scaling of color dissimilarities collected with a gestalt formation task.

The structure of color perception can be examined by collecting judgments about color dissimilarities. In the procedure used here, stimuli are presented three at a time on a computer monitor and the spontaneous grouping of most-similar stimuli into gestalts provides the dissimilarity comparisons. Analysis with multidimensional scaling allows such judgments to be pooled from a number of observers without obscuring the variations among them. The anomalous perceptions of color-deficient observers produce comparisons that are represented well by a geometric model of compressed individual color spaces, with different forms of deficiency distinguished by different directions of compression. The geometrical model is also capable of accommodating the normal spectrum of variation, so that there is greater variation in compression parameters between tests on normal subjects than in those between repeated tests on individual subjects. The method is sufficiently sensitive and the variations sufficiently large that they are not obscured by the use of a range of monitors, even under somewhat loosely controlled conditions.

Color Perception↗

A functional MRI case study of acquired cerebral dyschromatopsia.

Evidence from imaging studies suggests that primary visual cortex and multiple areas in ventral occipitotemporal cortex subserve color perception in humans. To learn more about the organization of these areas, we used structural and functional MRI (fMRI) to examine a patient with damage to ventral cortex. An art professor, KG, suffered a cerebrovascular accident during heart surgery that impaired his ability to perceive color. The Farnsworth-Munsell 100-Hue test was used to assess the extent of his deficit. When tested 12 months after the lesion, KG performed worse than 95% of age-matched normals on the 100-Hue test, but well above chance. Structural and functional MRI studies were conducted 3 years after the lesion to investigate the neuroanatomical correlates of KG'ss remaining color ability. Structural MRI revealed bilateral damage to ventral occipitotemporal cortex. In young and age-matched normal controls, an fMRI version of the 100-Hue reliably activated bilateral, color-selective regions in primary visual cortex and anterior and posterior ventral cortex. In subject KG, color-selective cortex was found in bilateral primary visual cortex. In ventral cortex, no color-selective activity was observed in right ventral cortex, and only a small area of activity was observed in left anterior ventral cortex. However, significant color-selective activity was observed in posterior left ventral cortex spared by the lesion. This posterior left ventral activation was similar in extent, position, and degree of color-selectivity to the posterior left posterior activation observed in normal controls, suggesting that this focus may be the cortical substrate underlying KG's remaining color perception.

Adult↗

Role of perceptual organization in chromatic induction.

Color matches between two small patches were made in a display containing ten larger regions of different chromaticities. The spatial organization of the ten regions was varied while keeping constant the immediate surround of each patch as well as the space-average chromaticity of the entire stimulus. Different spatial arrangements were designed to alter the perceptual organization inferred by the observer without changing the ensemble of chromaticities actually in view. For example, one arrangement of the ten regions was consistent with five surfaces under two distinct illuminations, with one edge within the display (an "apparent illumination edge") dividing the stimulus into two areas, one under illuminant A and the other under illuminant C. Another spatial arrangement had the ten regions configured to induce an observer to infer ten surfaces under a single illumination. When the ten regions were arranged with an apparent illumination edge, the patch within the area of illuminant C was perceived as bluer than when the same patch and immediate surround were presented without an apparent illumination edge. The results are accounted for by positing that observers group together regions sharing the same inferred illumination, with a consequent effect on color perception: A fixed patch-within-surround shifts in hue and saturation toward the perceived illumination. We suggest that the change in color perception in a complex scene that results from a difference in real illumination may be caused by the inferred illumination at the perceptual level, not directly by the physical change in the light absorbed by photoreceptors.

Adult↗

Evaluation of agreement among dermatologists in the assessment of the color of port wine stains and their clearance after treatment with the flashlamp-pumped dye laser.

BACKGROUND: Color classification and its subjective clearance evaluation in response to treatment are essential in the management of patients with port wine stains (PWS). But color perception by physicians is not an objective measurement so that it can change among observers. Agreement among physicians is essential for the reliability of the color classification and the clinical assessment of the response to laser treatment. OBJECTIVE: The purpose of our study was to determine the reliability of the clinical color classification of port wine stains and of their color change or clearance in response to laser treatment. The study was not designed to evaluate the outcome of laser treatment in PWS or the factors that could predict the final response. METHODS: We used the kappa index to evaluate the proportion of agreement in color and clearance perception among dermatologists. Six dermatologists classified the initial color of PWS in 80 patients. Three of them also assessed the amount of clearance achieved after treatment with the flashlamp-pumped dye laser. These three dermatologists were usually dedicated to treat patients with PWS, while the other three were not. RESULTS: The kappa index showed a substantial agreement in both cases. No difference in the initial color perception was observed between the group of dermatologists specialized in PWS and the other three dermatologists. CONCLUSION: These results favor the reliability of the clinical method in the assessment of PWS before and after laser treatment. So, although subjective, color perception by physicians can be used in the study of laser treatment outcome in PWS and its related factors, and the results of different authors can be compared.

Color↗

"Shades of beauty": examining the relationship of skin color to perceptions of physical attractiveness.

The purpose of this research project was to investigate the relationship between skin color and level of perceived physical attractiveness. Previous research suggested that skin color plays an important role in how we perceive an individual's physical attractiveness. The current study was conducted to determine how influential the role of race is on perceptions of physical attractiveness. In this study, 79 subjects were asked to evaluate images of potential endorsers to be used in an upcoming advertising campaign. The images were those of females of varying skin tones. Data were then collected and analyzed to determine whether skin tone and level of skin color can in fact influence the physical attractiveness stereotype.

Adolescent↗

A vision research apparatus for broad luminance range displays.

Lightness, the perceived gray shade of a surface, and the perception of self-luminous surfaces--that is, surfaces that appear to glow--have most often been studied with paper displays and computer-generated stimuli presented on CRT monitors. Although both methods are often effective, experiments that require a wide range of luminance values in the same display are often difficult to conduct with paper and computer displays alone. Also, color mode appearance is often an issue when surface color perception is the topic of research; CRT monitors are essentially light sources themselves and often appear in the luminous mode of color appearance. Here, we describe an apparatus in which the target is an undetected aperture whose luminance is adjustable. Whereas a typical CRT monitor offers a luminance range of about 100:1, much broader luminance ranges are possible with the described apparatus. Unlike a CRT monitor, the stimulus background will always appear in the surface mode of color perception, and the target(s) can appear as either surface colors or luminous colors. Apparatus modifications are possible, including the addition of a stereoscope or an embedded CRT for creating an adjustable region that is computer controlled.

Color Perception↗

Computer-based training of stimulus detection improves color and simple pattern recognition in the defective field of hemianopic subjects.

In a previously conducted randomized placebo-controlled trial, we were able to demonstrate significant visual field enlargement induced by restitution therapy in patients with cerebral lesions [Kasten, E., Wuest, S., Behrens-Bamann, W., & Sabel, B. A. (1998c). Computer-based training for the treatment of partial blindness. Nature Medicine, 4, 1083-1087.]. Visual field training was performed on a computer monitor for 1 hr per day over a period of 6 months. Since the procedure included only stimulation with white light, in the present study we investigated if this simple detection training had a transfer effect on color or form recognition in the trained area (i.e., in the absence of modality specific training). Answering this question would be crucial for planning optimal restitution therapy: In case there is no transfer of training effects to other visual modalities, a specific treatment of each visual function must be performed in order to achieve maximum benefit. Therefore, we analyzed the data from 32 patients with visual field defects who had participated in the original trial and whose form and color recognition had been investigated. The experimental group (n = 19, restitution training) experienced not only an increase of 12.8% correctly detected stimuli (PeriMa program, p <.05), but also an improvement of 5.6% in pattern recognition (PeriForm) and of 6.1% in color perception (PeriColor), respectively. In contrast, the placebo group (n = 13, fixation training) showed no significant changes from baseline to final outcome in any of the visual modalities (PeriMa: 0.3%; PeriForm: -0.3%; PeriColor: 0.4%). Conventional perimetry yielded an increase of 7.8% detected stimuli in the experimental group, but only of 1.2% in the placebo group (p <.05). For form recognition and color perception, the differences between the results of the experimental and the placebo groups narrowly missed significance. However, correlations of diagnostic results showed that mainly those patients who had achieved visual field enlargement also improved in color and form perception: r =.67 (p <.05) between PeriMa and PeriForm and r =.32 between PeriMa and PeriColor. We conclude that visual restitution training using a simple white light stimulus has at least some influence on improving other visual functions such as color and pattern recognition. This result supports the "bottleneck theory" of visual restitution, i.e., training effects can be explained as a process of perceptual learning and increased processing of information by residual structures surviving lesions of the primary visual pathways.

Audiovisual Aids↗