Urinary excretion of B-aminoisobutyric acid in liver disease.
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Piglets were infected with 5000 or 15,000 third stage larvae of Strongyloides ransomi/kg of body weight. On the 15th day post infection absorption of the amino acid 14C alpha-amino-isobutyric acid (AIB) and the fatty acid 3H palmitic acid were studied. It was found that the onset of absorption of amino and fatty acids was delayed in the infected animals. Defective absorption of the amino acid was found in heavily infected piglets, whereas in moderate infection there was no failure of absorption from the entire small intestine. There was no difference in the rates of absorption of 3H-palmitic acid between infected and control piglets.