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Results for “nutritional environment”

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PubMed1979

Nutrition, environment and physical performance of preschool children in Italy.

While overt malnutrition is known to interfere with several bodily functions and to cause a deterioration of the level of physical performance, little or no information is available on the effect of marginal nutrition on functional development, particularly at earlier ages. A cross-sectional study of the diet, somatic development and functional response to exercise of 2,241 children, aged 1-6 years, representing contrasting socioeconomic environments, has been carried out. The findings indicate that the upper socioeconomic urban child from Central Italy consumes a better diet and is larger than the underprivileged Southern child. While a greater proportion of the latter group experience a considerable degree of growth retardation, the better efficiency of their heart responses to exercise indicates that the level of nutrition of these children is still good enough to be compatible with a more satisfactory degree of physical fitness. The body fat content and skinfold thickness of the child from the Center have found to be significantly higher than those of the children from the poorer sections of the population, suggesting that at least part of the extra energy available to him for physical activity is being deposited as fat. This raises the question of the desirability of changes in somatic development characteristic of upward social mobility, when accompanied by increased adiposity without a proportional increase in the functional capacity.

Child↗
PubMed1988

Divergent selection for growth in Japanese quail under split and complete nutritional environments. 2. Water and feed intake patterns and abdominal fat and carcass lipid characteristics.

A study was conducted to investigate water and feed intake patterns, abdominal fat and carcass lipid levels, feed efficiency and growth in high (H) and low (L) body weight lines of Japanese quail divergently selected under complete diet (CD) or split diet (SD) environments. Birds under the SD environment could self-select from high-protein low-energy or low-protein high-energy diets. Progeny from both the selected and control (C) lines were evaluated under the SD environment in Generations 6 and 10, and under the CD environment in Generation 10. Under the SD environment, body weights of the H lines were similar as were body weights of the L lines; however, under the CD environment, there were significant differences between H lines and between L lines. Body weights were higher under the CD than under the SD environment. Differences between H and L lines in body weights and 1-wk relative growth rates within SD and CD environments were attributed to differences in water and feed consumption and feed efficiency. Water consumption was greater in the SD than CD environments. Feed consumption was greater in the SD than CD environment from 0 to 2 wk of age; thereafter, feed consumption was higher in the CD environment. Abdominal fat and carcass lipid levels were greater in H than L lines, with the magnitude of the difference greater in the SD environment, indicating that the SD may be a better environment than the CD environment for the study of abdominal fat and carcass lipids in Japanese quail.

Adipose Tissue↗
PubMed1999

Impact of the Working Well Trial on the worksite smoking and nutrition environment.

This article reports the effect of a worksite cancer control intervention on aspects of the physical and social environment related to dietary and smoking behaviors of employees. Data are from 111 intervention and control worksites that participated in the Working Well Trial. Employee surveys and interviews with key organizational informants assessed environmental and normative changes relevant to nutrition and tobacco use. Results indicated significant effects of the intervention on all nutrition outcomes: access to healthy food, nutritional information at work, and social norms regarding dietary choice. Significant benefits were not found for smoking norms or smoking policies. However, changes occurred in both the control and intervention sites on these variables. This first large analysis of environmental and normative effects of a worksite intervention is consistent with the employee behavior change findings for the trial and serves as a model for future analyses of multilevel worksite health promotion programs.

Adult↗
PubMed1990

Interactive effects of nutrition, environment, and rat-strain on cortical and vertebral bone geometry and biomechanics.

Because of differences between rodent experiments on USSR and USA spaceflights, the present experiment was designed to generate comparative data about the sensitivity of cortical (humerus) and vertebral (T7) bones to cage environment, diet, and rat-strain differences. For 2 weeks (48-62 d), male Taconic-Sprague-Dawley and Czechoslovakian-Wistar rats were maintained in flight-simulation cages (1 rat/cage = USA, 10 rats/cage = USSR) and fed either USSR or USA diets. All rats increased (greater than 60%) their body mass during the two weeks, and there were no differences among humeral lengths for the different groups. Rats in USSR cages had significantly larger total and medullary cross-sectional areas for the humerus, and the cross-sectional areas of T7 of Taconic rats were greater than the Czech rats. USSR caging resulted in significantly enhanced structural and material properties in rat humeri, while the USA diet produced significantly greater humeral maximum and failure loads. The flexural rigidity of the Czech-rat humeri was significantly greater than the Taconic rats. Humeri from Czech rats on the USA diet had significantly greater material properties in the elastic-loading region than did Taconic rats on the USSR diet. Further, the humeral failure loads of Taconic rats on the USSR diet were more adversely affected by USA cages than were the Czech rats on the USSR diet. In T7 vertebrae, no significant structural differences were found among the groups, but material properties were influenced by all three factors; generally, the combination of factors that produced the significantly greater T7 material properties was: USSR caging, USSR diet, and the Czech strain of rat.

Animal Nutritional Physiological Phenomena↗
PubMed1999

Cysteine protease SpeB expression in group A streptococci is influenced by the nutritional environment but SpeB does not contribute to obtaining essential nutrients.

Group A streptococcal (GAS) cysteine protease is a major virulence factor involved in the pathogenesis of purulent and invasive infections. The secreted enzyme cleaves a number of different bacterial and host proteins which could contribute to different stages of the infective processes. It has been proposed that, among these functions, SpeB plays a role in obtaining nutrients during late growth phases. In the present study, speB mutants of various GAS serotypes were found to exhibit unaltered growth characteristics in several complex and chemically defined media (CDM). When amino acid-depleted CDM was prepared, neither SpeB activity on whole proteins added to the medium during incubation nor the addition of SpeB-digested proteins was able to support bacterial growth. SpeB also was unable to liberate iron from iron-containing protein sources added to iron-deficient CDM. However, SpeB levels in culture supernatants changed in response to the protein and glucose content of the media. Using a speB promoter-luciferase reporter, speB expression levels were found to correspond to peptide concentrations in the culture media. The effect appeared to be specific for peptides since addition of peptides derived from various proteins had an affect on expression, while addition of the whole proteins had no effect. Addition of glucose to CDM had no effect on speB expression, while glucose addition to complex medium decreased speB expression. Overall, SpeB did not appear to be directly involved in providing the bacteria with nutritional factors but expression of the speB gene responded to ratios of peptides and carbohydrates in the culture medium.

Amino Acids↗
PubMed1990

Growth analysis in two lines of rats and their reciprocal F1 crosses under two nutritional environments. Heterosis for body weight and maturing rate.

The heterotic effects for body weight during the early postweaning period and on the von Bertalanffy growth equation parameters in relation with the growth pattern as a whole were investigated in rats with caloric restriction (20%) and in controls with ad libitum feeding. Body weight at fixed ages, weight-age curves, asymptotic weight, mature size and maturing curves were evaluated in a cross between two highly inbred lines of rats. Growth curve parameters were combined in a single value by the multivariate method of principal components in order to characterize the particular growth pattern of each group. Positive and significant heterotic effects for body weight were observed suggesting the presence of non-additive genetic variation for this trait. Additivity was an important source in asymptotic size. An heterotic response was observed in mature rate showing a dominant deviation towards high values of this character. Caloric restriction diminished body weight, but asymptotic size was not modified. Maturity was affected along the period studied. Hybrids reached an intermediate asymptotic weight in relation to parental lines exhibiting greater maturity in the prepuberal period. It is suggested that in livestock production crossbreeding will be profitable if additivity for asymptotic weight and dominance deviation for maturing rate could be combined in the F1 hybrid. Maternal breed should be lighter and mature more rapidly than the paternal one if maintenance costs of the breeding stock and growing potentiality of the crossbred progeny are considered.

Aging↗
PubMed1986

Isolation of a novel type of mutation in the mitotic control of Schizosaccharomyces pombe whose phenotypic expression is dependent on the genetic background and nutritional environment.

The major cell cycle control in the fission yeast Schizosaccharomyces pombe acts at entry to mitosis, and involves three previously identified genes cdc2, cdc25 and wee1. The presence of a wee1 mutation phenotypically suppresses cdc25 mutations. This paper describes the isolation and subsequent analysis of a strain in which the suppression is reversed by the presence of a new mutation, designated win1.1. The mutation causes a slight increase in cell size at division in most genetic backgrounds. However, when combined with a wee1 mutation and cdc25.22, the win1.1 mutation interacts strongly to generate a novel phenotype: cells are phenotypically cdc during growth on minimal medium but cdc+ when cultured on complex medium. The win1 locus is unlinked to previously identified genes involved in mitosis.

Cell Cycle↗
PubMed1987

Developmental changes in hepatic fructose 2,6-bisphosphate content and phosphofructokinase-1 activity in the transition of chicks from embryonic to neonatal nutritional environment.

Within 2 days of hatching in chicks, there are parallel increases in hepatic fructose 2,6-bisphosphate content and phosphofructokinase-1 activity. The changes observed are a consequence of feeding on the carbohydrate-rich diet of neonatal life: lack of access to food after hatching prevents changes for either parameter. The results are discussed in relation to changes in the activities of hepatic lipogenic enzymes during the embryonic/neonatal transition of chicks and the role of insulin in co-ordination of developmental processes.

Animals↗
PubMed1992

The Composition and Attributes of Colletotrichum truncatum Spores Are Altered by the Nutritional Environment.

Previous sporulation studies with Colletotrichum truncatum NRRL 13737, a fungal pathogen of the noxious weed Sesbania exaltata, showed that the carbon-to-nitrogen (CN) ratio of the conidiation medium influenced spore yield, morphology, and efficacy in inciting disease in S. exaltata. Spores produced in a medium with a CN ratio of 10:1 were more effective than were spores produced in a 30:1 or 80:1 ratio in causing disease in S. exaltata. With a basal salts medium supplemented with glucose and Casamino Acids, substrate utilization, spore production, biomass accumulation, and biomass and spore composition were compared in submerged cultures of C. truncatum grown in media with CN ratios of 80:1, 30:1, and 10:1. All cultures were sporulating by day 2, and spore concentrations in 5-day-old cultures were significantly different: 30:1 > 10:1 > 80:1. Amino acid and glucose utilization was balanced in cultures grown in media with a CN ratio of 10:1, whereas cultures grown in media with a CN ratio of 30:1 or 80:1 depleted amino acids prior to glucose. Conidia produced in media with a CN ratio of 10:1 contained significantly more protein (32% of dry weight) and less lipid (17% of dry weight) than conidia produced in media with a CN ratio of either 30:1 (15% protein, 33% lipid) or 80:1 (12% protein, 37% lipid). The higher lipid content of spores produced in media with a CN ratio of 30:1 or 80:1 was associated with the presence of increased numbers of lipid droplets. Optimization studies on conidia produced in media with CN ratios between 30:1 and 10:1 which compared yield, attributes, and efficacy in inciting disease in S. exaltata suggest that media with a CN ratio of 15:1 to 20:1 may be optimal for conidium production.

Journal Article↗
PubMed1983

Phenotype x nutritional environment interactions in forage intake and efficiency of Angus cows grazing fescue-legume or fescue pastures.

Forage intake, milk production, calf growth and efficiencies of milk production and calf growth were estimated for 198 lactations of 91 mature Angus cows grazing fescue-legume or fescue pastures. Cows calved January through March and calves were weaned in October in each of the 5 yr of the experiment. Cows grazing fescue-legume consumed 1.7 kg/d more (P less than .01) dry matter (DM) that was 4.6 percentage units more (P less than .01) digestible than cows grazing fescue. Cows grazing fescue-legume produced .4 kg/d more (P less than .01) milk and weaned 23.8 kg more (P less than .01) calf than cows grazing fescue. This increased production required an additional intake/cow-calf unit of 2.3 kg of digestible DM for each additional kilogram of calf weaned. Cows grazing fescue-legume were less efficient in calf production at least partially because they gained 33.3 kg more (P less than .01) weight and 1.82 mm more (P less than .01) fat cover at the 12th rib during lactation than cows grazing fescue. Cows producing relatively large amounts of milk consumed more digestible DM, weaned heavier calves, and were more efficient producers of milk and weaned calf regardless of pasture type grazed. The influence of milk production on these variables was more dramatic for cows grazing fescue than for those grazing fescue-legume. Cow type favoring maximum conversion of digestible DM intake by cow and calf to calf gain was different for the two types of pasture. For cows grazing fescue, those having either small amounts of fatness or having small structural sizes, regardless of milk production, were the most efficient. Structural size was not related to efficiency for cows grazing fescue-legume. Fatness had little influence on efficiency of low milking cows. The relationship of structural dimension and efficiency for cows grazing fescue was due to interrelationships of structural dimension, change in cow weight and fatness during lactation, and calf weaning weight: cow weight ratio. Relationships between efficiency and fatness could not be attributed to these variables.

Animal Feed↗