Human genetic disorders with defects in the repair of deoxyribonucleic acid [proceedings].
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Researches in which entire families as well as twins are subjected to careful examinations are rapidly assuming considerable importance within the framework of studies made to investigate the causes of irregular dentural characteristics. The author emphasizes the need for making genetic examinations of orthodontic patients, the results of which can be used to find the most favorable method of therapy. The author, on the basis of observations made on monozygotic and dizygotic twins, presents a number of data on the behavior of dental, dental arcade, and cephalometric dimensions as well as some dysgnathic characteristics. Special attention is given to twins with congenital cheiloschisis, gnathoschisis, and palatoschisis, and it is possible to show that the role played by hereditary factors in the etiology of such maldevelopments is not inconsiderable.
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