PubMed2004
This study investigated the texts attributed to Manase Gensaku (1549-1631, the second Mamase Dosan), successor to the first Manase Dosan (1507-1594). The investigation yielded the following results:(1) "Saiminki," "Sankyoshiyo Bassui" and "Iden Fukyuroku," said to have been authored by Manase Gensaku, constitute the first Manase Dosan's works. Manase Gensaku is thought to have revised "Saiminki," recompiled "Sankyoshiyo Bassui," and published "Iden Fukyuroku."(2) Manase Gensaku's medical writings, "Denshin Hoho," "Keitokuho" and "Jozanho," have the same contents.(3) Late in his life, Manase Gensaku wrote the pharmaceutical volumes, "Kyushin Zappo," "Iho Joboku" and "Iho Kenko." These books described pharmaceuticals that were described by Manase Dosan, as well as pharmaceuticals that were being developed at that time.(4) "Iho Meikan," the most important work of Manase Gensaku, contains descriptions of almost all of the pharmaceuticals described by the first Manase Dosan.(5) The principal aim of Manase Gensaku was the production of straightforward, compact and convenient medical texts that could be used by clinicians. This was because most of Manase Dosan's medical texts were too extensive to be useful for practicing clinicians of the time.(6) In addition to working on aspects of internal medicine investigated by Manase Dosan, Manase Gensaku made radical improvements in disciplines such as materia medica, regimens, acupuncture and moxibustion.