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PubMed2005

[Intestinal and disseminated strongyloidosis: two case studies].

Systemic strongyloidiasis is a rare but serious complication of intestinal strongyloidiasis. This condition occurs mainly in immunosuppressed patients and has a significant mortality rate. The use of immunosuppressive and cytotoxic treatment has increased its incidence. A better awareness of this infection with early diagnosis and treatment is essential. We report two cases of strongyloidiasis. The first, uncomplicated intestinal strongyloidiasis occurred in a 32-year-old HIV-positive women. The second case was fatal disseminated strongyloidiasis in a 14-year-old child who underwent prior surgery and radiotherapy with cortico sterpoid therapy for a malignant brain ganglioglioma. The pathological basis of intestinal and disseminated strongyloidiasis are discussed.

Adult↗
PubMed1974

A case of human strongyloidosis apparently contracted from asymptomatic colony dogs.

A 63-year-old, white, animal caretaker suffered intermittent abdominal pain and diarrhea of 3 weeks duration. Hematological findings included leukocytosis (18,600) with eosinophilia (73%). Fecal examination revealed Stongyloides rhabditiform larvae which on culture yielded a preponderance of filariform larvae and a few free-living adults. Thiabendazole therapy resulted in rapid recovery. Epidemiological investigation yielded no history of previous Strongyloides infection or exposure; his wife and pet dog were not infected, but about one-third of the dogs in the colony under his care were found to be discharging Stongyloides rhaditiform larvae in their feces. Strongyloides infection was successfully trasmitted to specific pathogen-free pups using filariform larvae derived both from the human case and from the dog colony. Specimens recovered from one pup infected with filariform larvae of human origin were identified as Strongyloides stercoralis.

Animals↗
PubMed1999

[Cutaneous manifestations of strongyloidosis].

Strongyloidiasis is a parasitic disease, caused by Strongyloides stercoralis, an intestinal nematode, which is mainly endemic in tropical and subtropical regions. It can be sporadically found in the temperate zone, especially in closed communities and among people living under bad social conditions. Gastrointestinal, pulmonary and cutaneous symptoms may arise during the migration of the larvae. The infections are chronic and poor in symptoms among immunocompetent patients. Sometimes the cutaneous manifestation is the only symptom of the disease besides the distinct eosinophilia. Intense itching, erythematosus papule and petechiae develop at the site of the skin infection. Rapidly progressing linear, serpiginous, urticarial streaks are the pathognomic cutaneous manifestations that are called larva currents. The appearance of erythematosus, linear stripes are due to the migrating larvae in the skin. The most common nonspecific symptoms are urticaria, maculopapular exanthema, localized or generalized pruritus and prurigo. The parasite is uniquely able to carry out its whole life cycle inside the human body, so in immunocompromised patients the disease can lead to a hyperinfection syndrome with high mortality, due to the accelerated endogenous autoinfection. Authors present all possible skin manifestations of the strongyloidiasis, based on the case history of three brothers and sisters and that of a female patient suffering from hyperinfection syndrome.

Aged↗