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PubMed2004

Pleasurable auditory hallucinations.

OBJECTIVE: The focus in auditory hallucination (AH) research is usually on the negative impact of the experience itself. There are practically no studies on whether voices can be perceived as pleasurable. The aim of the present study was to assess the frequency of voices as a pleasurable experience in a psychotic patient population. METHOD: A total of 160 patients with AHs (89 schizophrenia and 17 other psychoses) were assessed with the psychotic symptom rating scale (PSYRATS) for AHs, including an added item on whether the experience was pleasurable. RESULTS: Twenty-eight patients (26%) reported the voices as a pleasurable experience and 10 of them did so frequently. Pleasurable hallucinations showed negative associations with amount and intensity of distress, degree of negative content and loudness. Positive associations were apparent with chronicity and perceived control over the voices. CONCLUSION: Pleasurable hallucinations can be detected in a substantial proportion of patients, and cross validated with existing instruments.

Adult↗
PubMed2002

Pleasure in decision-making situations.

BACKGROUND: This study explores the role of pleasure in decision making. RESULTS: In Experiment 1, 12 subjects were presented with a questionnaire containing 46 items taken from the literature. Twenty-three items described a situation where a decision should be made and ended with a suggested solution. The other items served as filler items. The subjects were requested not to make a decision but to rate the pleasure or displeasure they experienced when reading the situation described in the item. The subjects' ratings were then compared to the decisions on the same situations made by the other subjects of the studies published by other workers. The ratings of pleasure/displeasure given by our subjects correlated significantly with the choices published by other authors. This result satisfies a necessary condition for pleasure to be the key of the decision making process in theoretical situations. In Experiment 2, a new group of 12 subjects rated their experience of pleasure/displeasure when reading various versions of 50 situations taken from daily life where an ethical decision had to be made (Questionnaire I) including 200 items. This was followed by a multiple-choice test with the 50 situations (Questionnaire II) using the same 200 items and offering the various behaviors. Subjects tended to choose ethical and unethical responses corresponding to their highest pleasure rating within each problem. In all cases the subjects' behavior was higher than chance level, and thus, followed the trend to maximize pleasure. In Experiment 3, 12 subjects reading 50 mathematical short problems followed by correct and incorrect versions of the answer to the problem (Questionnaire III), including 200 items. This was followed by a multiple-choice mathematical test with the 50 problems (Questionnaire IV) using the same 200 items and offering the correct and incorrect answers. In questionnaire IV, subjects tended to choose correct as well as incorrect responses corresponding to their highest hedonic rating within each problem. In all cases the subjects' behavior was higher than chance level, and thus, followed the trend to maximize pleasure. CONCLUSIONS: The results of the three experiments support the hypothesis according to which decisions are made in the hedonic dimension of conscious experience.

Adult↗
PubMedDate not supplied

[The Pleasure-Displeasure Scale. Use in the evaluation of depressive illness].

The Pleasure-displeasure Scale is a self-report instrument consisting of 82 items for measuring the intensity of subjects' affective responses to usually pleasant and unpleasant situations. 81 depressed inpatients were compared to 120 normal subjects. The responses of the depressed patients to the Pleasure sub-scale (French translation of the Fawcett-Clark's Pleasure Scale) are more anhedonic than those of the normal subjects; but the difference did not reach statistical significance. Pleasure scores in the depressive group are bimodally distributed; a distinct subset (11% of depressives) is characterised by an extremely anhedonic Pleasure score. The sensitivity to unpleasant stimuli is significantly greater in the depressive group; however this difference seems to be related rather to a low cultural level than to depression itself. Finally pleasure and displeasure scores are closely correlated: this could possibly imply that anhedonia is not an independent symptom but rather belongs to the wider constellation of affective anesthesia.

Adult↗
PubMed1980

Interrelationships and correlates of four measures of pleasure deficit.

Compared the utilities of four measures currently used to assess pathological deficit in the ability to experience pleasure (N = 56). The Watson Anhedonia Interview scale was less reliable than the others, but was correlated as often with measures of pleasure-seeking as they were after correction for attenuation. It was more heavily correlated with measures of psychopathology than the others. The Chapman, Chapman, & Raulin (1976) Social and Physical Anhedonia scales demonstrated superior reliability and more correlations with pleasure-seeking ratings than the other scales, at least before correction for attenuation. However, their relatively modest relationships with measures of psychopathology suggested that the pleasure-deficits they measure best may not be as characteristic of psychiatric conditions as that reflected by the Anhedonia Interview. The Zuckerman General Sensation Seeking scale showed less reliability than the Chapman scales and fewer correlations with both pleasure-seeking and psychopathology than the others.

Adult↗
PubMed1987

Pleasure and preference in a two-dimensional sensory space.

A matrix of 25 gustatory stimuli combined five sucrose concentrations (0.15 to 2.35 mole/l) with five temperatures (10 to 50 degrees C) or sournesses (pH 1.8 to 5.7). On four different days at the same time of day ten healthy young men served as subjects. Sweet pleasure/displeasure vs. temperature pleasure/displeasure was studied in four subjects and sweet pleasure/displeasure vs. sourness pleasure/displeasure in six subjects. Throughout the first session the 25 stimuli were presented for 5 s each and the subject gave a magnitude estimate of his pleasure or displeasure in response to one dimension of the matrix (e.g. sweetness) regardless of the other. Similarly, throughout the second session, the same stimuli were presented and the subject rated his pleasure or displeasure in response to the second dimension of the matrix (e.g. sourness or temperature) regardless of the first. For the third session however, the subject himself was invited to mix samples, this to allow a behavioural choice in one dimension of the matrix the other being imposed (e.g. he could mix sucrose and water ad libitum for five imposed temperatures). For the last session the subject could adjust the previously imposed dimension, the other previously adjustable dimension being now imposed (e.g. he could modify temperature for five imposed sucrose concentrations). The results of the first two sessions showed that pleasure/displeasure resulted from a two-dimensional combination of the taste modalities offered. The results of the last two sessions showed that the subjects tended to maximize their sensory pleasure. The operant choices coincided with the ratings obtained in the first two sessions. Whether a dimension of the matrix was imposed or operantly adjustable made no difference on the results; the subjects tended to maximize sensory pleasure in the imposed dimension as well as in the adjustable dimension. The subjects therefore maximized their pleasure in the two-dimensional space offered.

Adolescent↗
PubMed1985

Primitive pleasure as the basic human state.

Physiological homeostasis as a goal for much of nursing practice is put into question. The goal of primitive pleasure is substituted as a goal of nursing in that nurses assist people in returning to a basic state of pleasure. This basic human state is further specified as primitive pleasure, primitive in that it is sensory, sensual, and carnal as compared to cognitive or esthetic in nature. Propositions related to primitive pleasure as the basic human state are identified, described, illustrated, and discussed. This beginning conceptualization of an ideal human state was developed without examination of or relation to existing theories such as arousal, stimulation response, Freud's pleasure principle, or developmental theories.

Body Image↗
PubMed1984

Is capacity for pleasure associated with executive career success?

Executives with a low capacity for pleasure were examined to determine if they evidence less occupational and social success than those with normal or high capacity. Data on pleasure capacity and depressive symptoms were collected from 88 senior executive officers, and scores were compared with independent ratings of career success. The 11% of executives with serious work-related or personal problems showed significantly higher pleasure scores than the rest. It is hypothesized that the relatively high pleasure scores of the least successful executives reflect a defensive process of denial or reaction formation rather than an excessively joyful personality trait. A longitudinal study of executives is proposed to clarify whether the high pleasure capacity scores of the least successful executives change situationally over time.

Adult↗
PubMed1998

Children's sense of pleasure from nitrous oxide therapy during dental visits.

The purpose of the present study was to measure feelings of pleasure by children who were undergoing dental treatment under nitrous oxide therapy during consecutive treatment sessions, and at a six-month follow-up visit. Fifty-two children between the ages of 3 and 5 years (mean age 4.3 +/- 1.06) children, who required two or more operative treatment visits participated in the study. At the conclusion of the initial treatment and after sufficient time for the effects of the nitrous oxide therapy to subside, patients were asked about their feelings from the gas. At subsequent visits, patients were asked the same questions at the beginning of each treatment session. The same was done at the beginning of a six-month follow-up visit. In general, there was a decrease in pleasure among those who experienced three or more visits. Extraction, in addition to operative treatment, did not result in a decrease in the sense of pleasure from nitrous oxide therapy. A similar response was observed in the recall visits when the reactions of the children were compared with the reactions at the last dental appointment. It is concluded that the sense of pleasure is strengthened through the second visit, but that the sense of pleasure and ability to cope is overwhelmed by the inconvenience of the dental treatment at the third visit.

Anesthesia, Dental↗
PubMed1989

[Maximization of pleasure, the answer to a conflict of motivations].

An experiment has been set up to explore the hypothesis according to which behaviour is determined by the trend to maximize pleasure. Twelve subjects were placed individually in a situation of conflict where the pleasure of playing a videogame clashed with the increasing discomfort of a cold environment. The time lapse tolerated could be predicted from the algebraic sum of the rating of displeasure aroused by the cold environment and the rating of pleasure aroused by the videogame, obtained in other sessions. This result supports the working hypothesis and allows to conclude that pleasure is the common currency of tradeoffs among various motivations.

Cold Temperature↗
PubMed1987

Sexual anxiety and female sexual arousal: a comparison of arousal during sexual anxiety stimuli and sexual pleasure stimuli.

Sexual arousal occurring during sexual anxiety stimuli was compared to sexual arousal occurring during sexual pleasure stimuli in 19 sexually functional women. Stimuli were individualized narratives based on descriptions given by each subject. Sexual arousal was measured by monitoring vaginal blood flow with a vaginal photoplethysmograph. Results showed significant increases in vaginal blood flow in response to both sexual anxiety and sexual pleasure. However, increases in the pleasure condition were significantly greater than those in the anxiety condition. Analysis of the blood flow across time showed a significant linear increasing trend in the pleasure condition and a lack of such a trend in the anxiety condition.

Adolescent↗
PubMed1978

Female self-report and autonomic responses to sexually pleasurable and sexually aversive readings.

This study was designed to investigate possible differential autonomic responses to sexually pleasurable and sexually aversive readings. Reading conditions were counterbalanced so that an equal number of subjects received both orders of the two readings. Female subjects' ratings, skin conductance (SC), finger pulse (FP), and heart rate (HR), in response to these readings were compared. The sexually pleasurable as compared to the sexually aversive passage was rated as more sexually stimulating, less anxiety and guilt provoking, and less disgusting, but as equally well portrayed and interesting (extent of boredom). While essentially equal SC increases were noted in response to both readings, HR deceleration and vasodilation were more characteristic of the response to the sexually pleasurable passage. These findings were compared within the context of preexperimental setting conditions and were interpreted in terms of Lacey's intake-rejection hypothesis. These findings are consistent with the idea that pleasurable sexual readings are associated with interest, attention, and heart rate deceleration, whereas aversive material may be related to rejection of the material and to heart rate acceleration.

Arousal↗
PubMed1992

Pleasure: the common currency.

At present as physiologists studying various homeostatic behaviors, such as thermoregulatory behavior and food and fluid intake, we have no common currency that allows us to equate the strength of the motivational drive that accompanies each regulatory need, in terms of how an animal or a person will choose to satisfy his needs when there is a conflict between two or more of them. Yet the behaving organism must rank his priorities and needs a common currency to achieve the ranking (McFarland & Sibly, 1975, Phil. Trans. R. Soc. Lond. 270 Biol 265-293). A theory is proposed here according to which pleasure is this common currency. The perception of pleasure, as measured operationally and quantitatively by choice behavior (in the case of animals), or by the rating of the intensity of pleasure or displeasure (in the case of humans) can serve as such a common currency. The tradeoffs between various motivations would thus be accomplished by simple maximization of pleasure. In what follows, the scientific work arising recently on this subject, with be reviewed briefly and our recent experimental findings will be presented. This will serve as the support for the theoretical position formulated in this essay.

Animals↗
PubMed1999

Experiencing Pleasure in Working with Severely Disabled Children.

This qualitative research study examines the author's experience of pleasure in working as a music therapist with children with severe, multiple disabilities. The impetus for the study came when she experienced great pleasure in working with these children, and sought to better understand what made the experience so enjoyable. Videotapes of music therapy sessions were studied from several angles, and the following categories into which enjoyable experiences fit were formulated: Intentionality (allowing assistance, continuing on own after assisted initiation, initiation upon request, spontaneous initiation); emotionality (smiling, physical closeness); communication (humming, specific sounds or words); and mutuality (with another child, with therapist, upon request, with physical cues, spontaneous). Themes of responsiveness and expectations were found to run throughout the author's experience of pleasure, and she relates these themes to other areas of her life. Possible applicability to others, both in ways in which the findings might be used directly, and ways in which themes (such as her themes of responsiveness and expectations) might be used to increase others' understanding of themselves as therapists, are discussed. It is suggested that when music therapists make connections between their personal lives and clinical enjoyment, it can help them to find more pleasure in their work and thus better serve their clients.

Journal Article↗
PubMed1979

Differences between self-reported and observed pleasure in depression and schizophrenia.

Observer ratings of positive affect and self-ratings of pleasurable experience were collected daily on six schizophrenic and five depressed inpatients during baseline medication-free periods ranging from 11 to 27 days. Schizophrenics were observed to display significantly higher degrees of positive affect than depressed patients, but they reported significantly lower degrees of experienced pleasure. Depressed patients, conversely, were observed to demonstrate significantly lower degrees of positive affect than schizophrenics, but they reported significantly higher degrees of experienced pleasure. These results have important implications for the further specification of mechanisms underlying abnormalities in pleasure associated with psychiatric disorders.

Activities of Daily Living↗
PubMed2002

The core of loneliness: lack of pleasurable engagement--more so than painful disconnection--predicts social impairment, depression onset, and recovery from depressive disorders among adolescents.

Following past work, we proposed that loneliness possesses a bidimensional structure, with dimensions corresponding to lack of pleasurable engagement and painful disconnection. Moreover, we hypothesized that the distinction between lack of pleasurable engagement and painful disconnection would emerge in confirmatory factor analyses, in the pattern of relations of each facet to social impairment, in differential risk for the development of depressive disorders, and in differential rates of recovery from depressive disorders. Data from the Oregon Adolescent Depression Project were used to address these issues. Adolescents from high schools in urban and rural Oregon completed interviews and questionnaires on psychiatric status, loneliness, social functioning, and so forth, at one point in time and then again at a second session approximately a year later. Consistent with predictions, we found that the proposed bidimensional structure of loneliness represented a good fit to the covariance structure of loneliness items; the relation of lack of pleasurable engagement to social impairment exceeded that between painful disconnection and social impairment; and lack of pleasurable engagement, but not painful disconnection, was significantly related (in the expected directions) to onset of and recovery from depressive disorders. We discuss theoretical and clinical implications.

Adolescent↗
PubMed2004

Processing fluency and aesthetic pleasure: is beauty in the perceiver's processing experience?

We propose that aesthetic pleasure is a function of the perceiver's processing dynamics: The more fluently perceivers can process an object, the more positive their aesthetic response. We review variables known to influence aesthetic judgments, such as figural goodness, figure-ground contrast, stimulus repetition, symmetry, and prototypicality, and trace their effects to changes in processing fluency. Other variables that influence processing fluency, like visual or semantic priming, similarly increase judgments of aesthetic pleasure. Our proposal provides an integrative framework for the study of aesthetic pleasure and sheds light on the interplay between early preferences versus cultural influences on taste, preferences for both prototypical and abstracted forms, and the relation between beauty and truth. In contrast to theories that trace aesthetic pleasure to objective stimulus features per se, we propose that beauty is grounded in the processing experiences of the perceiver, which are in part a function of stimulus properties.

Affect↗
PubMed2006

Extended-release bupropion for patients with major depressive disorder presenting with symptoms of reduced energy, pleasure, and interest: findings from a randomized, double-blind, placebo-controlled study.

OBJECTIVE: This multicenter, double-blind, placebo-controlled study evaluated the efficacy and safety of extended-release bupropion (bupropion XL) in the treatment of major depressive disorder (MDD) with prominent symptoms of decreased energy, pleasure, and interest. METHOD: Eligible adult outpatients meeting DSM-IV criteria for MDD were randomly assigned to bupropion XL 300 to 450 mg/day (N = 135) or placebo (N = 139) for 8 weeks. The primary efficacy measure, change from baseline on the 30-item Inventory of Depressive Symptomatology-Self Report (IDS-IVR-30) total score, was obtained using interactive voice response (IVR) technology. Secondary measures included change from baseline on the 30-item Inventory of Depressive Symptomatology-Clinician-Rated (IDS-C-30) total score and change in domain subset scores for energy, pleasure, and interest; for insomnia; and for anxiety. Response and remission rates were also calculated. Safety was assessed by withdrawal rates, adverse events (AEs), body weight, and vital signs. The study was conducted from June 24, 2003, to June 30, 2004. RESULTS: Bupropion XL was superior to placebo at endpoint in reducing the IDS-IVR-30 total score (p = .018) and the energy, pleasure, and interest domain (p = .007) and the insomnia domain (p = .023) scores. IDS-C-30 outcomes were also significant (p < .001; p < .001, and p = .008, respectively). Clinician-rated remission rates were significantly higher with bupropion XL than placebo (32% vs. 18%, IDS-C-30; 41% vs. 27%, IDS-IVR-30), as were response rates (50% vs. 35%, IDS-C-30; 53% vs. 38%, Clinical Global Impressions-Improvement of Illness). Most AEs were mild or moderate. The incidence of a >or= 7% body weight loss was 3.7% with bupropion XL and 1.4% with placebo. CONCLUSION: Bupropion XL was effective and well tolerated in MDD patients with decreased energy, pleasure, and interest.

4-Aminopyridine↗
PubMedDate not supplied

Psychooncology and cancer progression-related alterations of pleasure-associated neurochemical system: Abnormal neuroendocrine response to apomorphine in advanced cancer patients.

OBJECTIVES: The clinical approach of the Psychooncology is generally limited to the investigation of the only psychological status of cancer patients, without taking into consideration the well demonstrated cancer progression-related psychoneuroendocrine alterations, namely consisting of a progressive decline in the pineal endocrine function and an anomalous activity of brain opioid system. The endocrine response to apomorphine, a dopaminergic agent, has been proven to reflect the dopaminergic sensitivity, which would be involved at least in part in pleasure-related neurochemical mechanisms. The present study was performed to analyze the endocrine response to apomorphine in metastatic cancer patients, as a preliminary approach to the investigation of pleasure-related neuroendocrine mechanisms in human neoplasms. MATERIALS & METHODS: The study included 10 metastatic cancer male patients and 6 male volunteers as a control group. Apomorphine was given orally at 0.01 mg/kg body weight in the morning, and venous blood samples were collected before, and at 20, 60 and 120 minutes after apomorphine administration. The endocrine analysis consisted of the measurement of serum levels of GH, PRL and cortisol. RESULTS: All cancer patients presented alterations involving one or more endocrine responses to apomorphine. GH and cortisol mean levels after apomorphine were significantly higher in controls than in cancer patients, whereas no substantial difference occurred in those of PRL. CONCLUSIONS: This preliminary study, by showing an altered endocrine response to apomorphine in metastatic cancer patients, would suggest that cancer progression may be associated with an altered dopaminergic sensitivity. Because of the involvement of the dopaminergic system in pleasure-related neurochemical mechanisms, this finding would demonstrated that the decline in the perception of pleasure with cancer progression may depend not only on psychological factors, but also, at least in part, on psychochemical alterations occurring during the clinical course of the neoplastic disease.

Adult↗