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Pneumothorax is a rare complication of percutaneous needle aspiration of suspected upper pole renal cysts. This complication is of particular concern in elderly patients with compromised cardiopulmonary reserve who undergo this procedure on an outpatient basis. An upright expiratory chest film is recommended following needle aspiration of upper pole lesions for detection of asymptomatic pneumothorax.
Anaphasis may be slightly checked by various treatments which however result in a normal chromosomic separation. Griseofulvin exerts a direct though partial influence on the mitotic apparatus, which entails "pluripolar anaphasis"; on the other hand Ipecac alkaloïds act indirectly and produce "floating poles anaphases". Treatments combining griseofulvin with cepheline or tubulosine show that there is never any synergy between the two processes. These results support our hypothesis that floating poles anaphases are not a sign of slight C-mitotic action but only come from a lag between the appearance/disappearance of microtubules and that of chromosomes during anaphasis.
In 4 baboons and 3 macaques ablation of the frontal pole (area 10) as compared to other areas of the frontal cortex did not impair previously elaborated instrumental reflexes of different complexity and did not interfere with the elaboration of new ones. An increase in stability, speed, accuracy and intensity of conditioned reflexes was noted. The ablation did not result in motor or vegetative disturbances. In the general behaviour inhibitory elements disappeared along with an enhancement in motor goal-directed activity. It is suggested that frontal poles do not participate in closing-function but control conditioned reflexes and complex behaviour by means of inhibitory influences.
The symptoms of Alzheimer's disease (AD) are caused by neurodegeneration and atrophy in particular brain regions, especially in the temporal lobe. However, the influence of genetic risk on cortical thickness prior to dementia onset, remains unclear. This study aimed to explore the relationship between AD genetic risk (related to APOE and PICALM genes) and cortical thickness in selected regions of interest (ROIs) in middle-aged individuals without dementia. Sixty-nine (N = 69) participants (34 females, 35 males; age: 55.45 ± 3.19) underwent magnetic resonance imaging (MRI). They were divided into three groups based on their genetic AD risk: A+ P+ (APOE/PICALM risk variants), A+P- (APOE risk variant, PICALM neutral variants), and the N group (APOE/PICALM neutral alleles). Cortical thickness was analyzed using CAT12 software (surface-based morphometry with the Destrieux atlas) based on T1-weighted MR images in five ROIs referred to as "the cortical signature of AD" in previous studies. The A+P- group had a thinner right temporal pole cortex than non-carriers after controlling for sex, age, and Raven's Progressive Matrices scores. Although this finding did not survive FDR correction across the 10 tested regions, it is consistent with our hypotheses and prior literature. No other differences in cortical thickness were found in the analyzed regions of AD "signature". The observed effect was restricted to single-risk APOE carriers without PICALM risk alleles. Therefore, further research is needed to understand the genetic interplay between these two genes in conferring AD risk.
Eighty-three intravenous pyelograms were studied to evaluate thinning of the parenchyma on the medial edge of the superior pole of the kidney as an indicator of vesicoureteral reflux. The data indicate that this finding is suggestive of reflux: the greater the difference between the two sides, the more likely the patient is to reflux.
The authors give a survey concerning history and operation techniques, indications and use of the renal pole resection. They report on the method developed by them, by means of which the effect of haemostasis is increased, the loss of parenchyma is decreased and the patients may earlier be mobilized. Their experiences are based on the observation of 29 patients operated by means of the method described.
The development of a tumor on the superior pole of a horseshoe kidney is an event which, although rare, still presents the surgeon very specific problems related to the anatomy of the malformation. The presence of a parenchymal pons, the multiplicity and anomalies in the origin of arteries are all factors to be taken into consideration in the selection of a surgical procedure. It is of particular importance that the approach be very wide in order to combine the advantages of the trans-peritoneal approach with that of the thoraco-phrenic laparotomy. One case is presented, and the surgical solution is discussed.
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