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[Skin flap reconstruction of the entire penile circumference. An unusual advanced case of penile induration (Peyronie's disease)].

One case was selected for presentation from our 17 operated cases for far advanced Peyronie's disease. The patient had complete circumferential involvement of the tunica albuginea with severe calcification on the dorsal aspect of the penile shaft. The case is exceptional in three aspects: a Peyronie's plaque may extend all around the penile shaft and involve the ventral aspect of the tunica between the corpora and corpus spongiosum of the urethra. Secondly, the extensive fibrosis and calcification may cause a spontaneous type of pain which is unrelated to erection. Finally, the application of a tubular-fashioned and sutured dermal graft around the penile shaft after the extensive excision of the tunica albuginea may lead to an excellent result. From a functional viewpoint, the result was a failure.

Humans↗

Value of magnetic resonance imaging in patients with penile induration (Peyronie's disease).

Magnetic resonance imaging (MRI) is a noninvasive procedure that enables exact imaging of penile anatomy. A total of 34 patients with clinical Peyronie's disease underwent palpation, ultrasound and MRI after intracavernous injection of 10 micrograms. prostaglandin E1. MRI images were obtained before and after intravenous application of gadolinium-diethylenetriaminepentaacetic acid. In 34 patients 45 plaques were palpable. Ultrasound revealed evidence of lesions in 66.6% of the cases. On MRI 36 of 45 palpable plaques (80%) were detected. Not palpable or sonographically revealed indurations could be shown in 4 cases. After intravenous application of gadolinium-diethylenetriaminepentaacetic acid 4 plaques demonstrated contrast enhancement, thus indicating local inflammatory activity. The combination of clinical examination and sonography remains the method of choice for diagnosis and observation of patients with Peyronie's disease. MRI enables exact imaging of penile structures but it does not provide a significant advantage over standard investigative procedures.

Adult↗

[Classification of plastic penile induration (Peyronie's disease)].

In this work an attempt has been made to find a general nosological formula of induratio penis plastica in order to compare the typical and numerous possibilities of therapy. The author has developed a classification based on the T.N.M. system, whereby the typical parameters of this disease, such as the grade of induration and deviation, as well as the subjective symptoms of pain and the ability of penetration has been considered in this system. The size of the indurations and the number of solidifications are as important as the site. This nomenclature makes it possible pro futuro to obtain a comparative therapeutic assessment in induratio penis plastica and, hence, to obtain guidelines on the indication for the optimal therapy of Peyronie's disease.

Erectile Dysfunction↗

[Is there a renaissance of conservative therapy in plastic penile induration?].

The management of Peyronies's disease should include an exact pretherapeutic staging. Diagnostic methods like ultrasound imaging, X-ray using "mammography technique" and magnetic resonance imaging are modalities of choice. The good results of new conservative therapy options have to be evaluated in randomized multicentric studies. Surgical therapy shows good results in patients with calcified plaques.

Algorithms↗

[An unusual case of plastic penile induration].

The presence of calcified plaques is one of the few unequivocal indications for surgery of Peyronie's disease. The mean size of plaques described in the literature is 1.5-2 cm whereby it may vary from 1 mm all along the penis. The authors treated successfully an unusually large calcified plaque 7 x 0.8 cm with excellent postoperative results--restoration of the patient's full sexual activity which was not possible before operation.

Humans↗