Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Neurosurgical Procedures”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources
PubMed2002

Noninvasive carbon dioxide monitoring during neurosurgical procedures in adults: end-tidal versus transcutaneous techniques.

BACKGROUND: We prospectively compared transcutaneous (TC) versus end-tidal (ET) carbon dioxide monitoring during neurosurgical procedures in adults. METHODS: After calibration and an equilibration time for the TC-CO2 monitor, arterial blood gas (ABG) values were obtained as clinically indicated. The PaCO2 values were compared with the values recorded by the noninvasive monitors (TC and ET). RESULTS: The ET-CO2 to PaCO2 difference was 6.1 +/- 5.6 mm Hg, and the TC-CO2 to PaCO2 difference was 3.7 +/- 2.9 mm Hg. The difference between the PaCO2 and ET-CO2 was 3 mm Hg or less in 17 of 57 values, while the difference between the PaCO2 and TC-CO2 was 3 mm Hg or less in 35 of 57 values. Linear regression analysis of ET-CO2 versus PaCO2 revealed a slope of 0.381 +/- 0.007. Linear regression analysis of TC-CO2 versus PaCO2 revealed a slope of 1.17 +/- 0.008. CONCLUSION: Transcutaneous CO2 monitoring provides a more accurate estimate of PaCO2 than ET-CO2 monitoring during neurosurgical procedures.

Adolescent↗
PubMed2000

Anesthetic considerations for thoracic neurosurgical procedures.

Anesthetic considerations for thoracic and thoracoscopic neurosurgical procedures are considered, emphasizing the need to provide anesthetic stability during prolonged periods of one-lung ventilation, while optimizing conditions for intraoperative monitoring of spinal cord integrity.

Journal Article↗
PubMed1998

Intraoperative on-line monitoring of cerebral pH by microdialysis in neurosurgical procedures.

The objective of this study was to improve the ability to detect cerebrovascular complications in patients undergoing complicated neurosurgical procedures using on-line monitoring of cerebral pH with in vivo microdialysis. We employed on-line pH monitoring in patients with a variety of neurosurgical procedures including high-flow bypass surgery, aneurysm clipping, and temporal resection in epilepsy treatment. The pH was monitored with a microdialysis probe, usually inserted into the frontal cortex and pH of the dialysate was measured on-line with a pH electrode. We monitored 17 cases: 12 high-flow extracranial-intracranial (EC-IC) bypass procedures, 3 surgeries to clip large basilar tip aneurysms under protection of hypothermic circulatory arrest, and 2 surgeries for intractable seizure disorders. In the patients undergoing high-flow bypass, the pH remained stable in 5 patients and all had an uneventful outcome. In 3 patients, the pH decreased during surgery. One patient had a severe hemiparesis on awaking from anesthesia. The fall in pH in another patient was corrected when the blood pressure was raised during surgery. The pH was also responsive to changes in intraoperative ventilation and probably also to brain edema with elevation of pH values. In the three patients undergoing basilar tip aneurysm clipping under hypothermic circulatory arrest, the pH fell to 6.41 in one patient. This patient awoke with a mild hemiparesis. In the other two patients, the pH was stable during the hypothermia and neither patient had complications. In the patients undergoing temporal lobectomy and hippocampectomy, the pH fell rapidly with the onset of ischemia. We conclude that it is possible to monitor the cerebral extracellular pH with on-line microdialysis. The information obtained may alert the surgeon to the possibility of impending cerebral ischemia or other complications. However, further experience is needed before the technique can be recommended for general use.

Adult↗
PubMed1992

Severe limitation in mouth opening following transtemporal neurosurgical procedures: diagnosis, treatment, and prevention.

Five new patients and six previously described patients with severe limitation in maximum mouth opening following transtemporal neurosurgical procedures are described. Six patients underwent an operation for epidural hematoma and three for skull-base meningloma; two were treated with a pterional craniotomy for an aneurysm. Limited maximum mouth opening in these circumstances is caused by temporal muscle scarring and shortening. Aggressive physiotherapy is potentially beneficial if started early. If, however, diagnosis is delayed, the efficacy of physiotherapy declines, and surgical treatments such as temporal muscle detachment and coronoidectomy are fully indicated. The differential diagnosis, prevention, and treatment of limited maximum mouth opening following neurosurgical procedures are discussed.

Adult↗
PubMed2002

Waterjet dissection in neurosurgical procedures: clinical results in 35 patients.

OBJECT: Waterjet dissection represents a new minimally traumatic surgical method for dissection that can be used in various parenchymal organs, in which it allows highly precise parenchymal dissection while preserving blood vessels, resulting in reduced intraoperative blood loss. This study was performed to investigate the clinical application of this new technique in neurosurgical procedures, such as brain tumor resection and epilepsy surgery. METHODS: Thirty-four patients with gliomas (Grades II-IV), cerebral metastases, temporal lobe epilepsy, or cerebellar hemangioblastomas, and one patient with internal carotid artery (ICA) stenosis were treated surgically with the aid of the waterjet. Resection was performed using waterjet dissection in combination with conventional neurosurgical procedures. Intraoperatively, the waterjet was easy to handle, and no complications due to the device were observed. Dissection of tissue was possible for all pathological conditions, and pressures between 3 and 45 bars were used. In gliomas, metastases, epilepsy surgery, and hemangioblastoma, the tissue was dissected at pressures between 3 and 17 bars, which preserved blood vessels. Dissection of meningiomas and the ICA stenosis required higher pressures (between 20 and 45 bars); with these pressures, blood vessels were also dissected. CONCLUSIONS: These results indicate that the waterjet dissection procedure can be used intraoperatively without complications. This device appears to be particularly suitable for the dissection of highly vascularized gliomas or normal brain tissue, in which tissue dissection with sparing of blood vessels can be achieved. To prove that this is a useful addition to the neurosurgical armamentarium, reduction of blood loss or postoperative brain edema compared with conventional methods should be demonstrated in future studies.

Adolescent↗
PubMed2003

The use of hypothermia as a method of neuroprotection during neurosurgical procedures and after traumatic brain injury: a survey of clinical practice in Great Britain and Ireland.

Hypothermia has been employed as a method of neuroprotection for many decades. The evidence base for its use is limited, and the balance between benefit and risk is unclear. We felt that in light of this confusion it would be interesting to canvas the opinion of the members of The Neuroanaesthesia Society of Great Britain and Ireland. A questionnaire was sent to all 274 members enquiring into their use of hypothermia during a variety of different neurosurgical procedures and in the management of the head-injured patient. A 75% response rate was achieved. The results showed that over half (58%) of those who replied attempted to cool the patient during cerebral aneurysm surgery. Forty-one per cent of respondents attempt to induce hypothermia in the head-injured patient. However, for other neurosurgical procedures most felt that the disadvantages of cooling the patient outweigh the advantages. The use of hypothermia remains a contentious issue, and as yet there is no clear answer as to whether it should be employed as a method of neuroprotection.

Adult↗
PubMed2004

A comparison of frontal and occipital bispectral index values obtained during neurosurgical procedures.

UNLABELLED: We placed bispectral index (BIS) sensors on the frontal and occipital areas of neurosurgical patients and compared BIS values obtained from both areas during propofol/fentanyl anesthesia. BIS showed a strong correlation between frontal and occipital montages (r(2) = 0.96; P = 0.03). It may be valid to measure BIS with the sensor on the occipital area if required during frontal neurosurgical procedures. IMPLICATIONS: Bispectral values were positively correlated when recorded from frontal and occipital sensors in patients undergoing clipping of unruptured cerebral aneurysms while anesthetized with propofol and fentanyl.

Adult↗
PubMed1999

Early postoperative complications following neurosurgical procedures.

PURPOSE: To assess the incidence and characteristics of early postoperative complications in patients following neurosurgical procedures. METHODS: All patients undergoing neurosurgery during a four month period were followed postoperatively for up to four hours in the post anesthetic care unit or intensive care unit. Patient information and all complications were documented by the investigators on a standardized form. Complications were classified as respiratory, cardiovascular, nausea and vomiting, shivering and other. Risk factors analyzed for the occurrence of complications included age, sex, ASA status, type of surgery, elective or emergency surgery and postoperative placement. RESULTS: Four hundred eighty six adult patients were followed, but in 55 patients the trachea remained intubated during the four hour study period and they were eliminated from the analysis of postoperative complications. At least one complication occurred in 54.5% of the remaining 431 patients. Respiratory problems occurred in 2.8%, trauma to the airway in 4.4%, cardiovascular complications in 6.7%, neurological in 5.7% and nausea and/or vomiting in 38%. The highest incidence of patients with complications was during spine (65%) and vascular (66%) surgery, compared with tumour (47%) and other (43%) surgery, P < 0.05. Other risk factors included age < 70 yr for nausea and vomiting (P < 0.02), and elective surgery for spine and vascular surgery (P < 0.001). CONCLUSION: There was a high incidence of early postoperative complications in neurosurgical patients. The most common problem was nausea and vomiting especially in the younger patient undergoing elective spine surgery.

Adult↗
PubMed1991

[Bacterial meningitis in the elderly with neurosurgical procedures].

Bacterial meningitis is one of complications in the elderly with neurosurgical procedures. In an attempt to find the clinical features of this complication we analyzed 10 cases, which were found in 30 cases of the bacterial meningitis in Tokyo Metropolitan Geriatric Hospital from 1972 to 1989. The patients were 4 males and 6 females, 52-86 years old (the mean, 69). While 2 Enterococcus species were isolated after craniotomy, Staphylococci were common pathogens (4 S. aureus, 4 S. epidermidis and 1 P. aeruginosa) in patients with shunt infection. Most of these patients lacked typical manifestations of meningitis except the fever. Symptoms occurred long after surgery with little abnormality in the data of serum and cerebrospinal fluid. However, blood cultures were positive in 75% of the cases. Removal of the infected catheter was effective in the cases of shunt infection.

Aged↗
PubMed1977

Neurosurgical procedures in Olmsted County, Minnesota, 1970-1974. Neurosurgical needs of a community.

To help determine neurosurgical needs within communities and within the nation, operations and diagnostic procedures performed by neurosurgeons on residents of Olmsted County, Minnesota, in the 5 years of 1970 through 1974, were tabulated. This county was studied because its medical records are virtually complete. Annual rates (per 100,000 population) were 42 for lumbar disc removal, six for cervical disc removal, and seven for brain-tumor therapy. Other less frequent occasions for neurological surgery are also tabulated.

Humans↗
PubMed2005

Using Dermabond for wound closure in lumbar and cervical neurosurgical procedures.

OBJECTIVE: 2-Octylcyanoacrylate (Dermabond; Ethicon, Inc., Somerville, NJ) is a liquid adhesive being used with increasing frequency for the closure of lacerations and surgical incisions. Dermabond provides excellent cosmetic closure, and recent studies have demonstrated very low infection risks when it is properly applied. There are no published studies using Dermabond on lumbar or cervical procedures. This study was undertaken to determine whether Dermabond is safe and efficacious to use in these common neurosurgical procedures. METHODS: Records of 200 consecutive patients with Dermabond closure after anterior cervical discectomy, microlumbar discectomy, or lumbar laminectomy by the senior author (JEB) with a mean follow-up time of 5.42 months were retrospectively reviewed. Suspected infections with or without confirmatory cultures, erythema, and incisional drainage were documented. RESULTS: Of 200 patients, 85 underwent microlumbar discectomy, 22 lumbar laminectomy, and 93 anterior cervical discectomy. There was only 1 definitive infection, which was a culture-proven discitis in a microlumbar discectomy patient. Of the remaining 85 microlumbar discectomies, there was 1 transient incisional erythema. Of the 22 lumbar laminectomies, there was 1 patient with clinical superficial wound infection with negative cultures and 4 patients with transient incisional drainage without infection. Of the 93 anterior cervical discectomies, 2 had transient incisional drainage without infection. CONCLUSION: This study demonstrates that Dermabond is safe to use in neurosurgery patients undergoing lumbar or cervical procedures, with only 1 patient of 200 having a proven infection. Patients are able to shower and do not have sutures or staples to remove. Patient responses are overwhelmingly positive.

Cervical Vertebrae↗
PubMed2003

C-reactive protein levels following standard neurosurgical procedures.

BACKGROUND: The aim of the present study was to establish the magnitude and time-course of C-reactive protein increases following routine neurosurgical procedures in the absence of clinical and laboratory signs of infection. METHOD: C-reactive protein levels were studied daily following ventriculo-peritoneal shunt implantation, anterior cervical fusion, vestibular schwannoma operation, supratentorial glioma surgery, endovascular intracranial aneurysm treatment and open cerebral aneurysm surgery. FINDINGS: The magnitude of the C-reactive protein increase depended on the extent of surgical trauma and peak-levels were recorded between postoperative day one and four after which the levels tapered off. INTERPRETATION: Increases occurring after the fourth postoperative day are likely to be caused by complications of surgery, e.g. infection.

Adult↗
PubMed1997

The present and future role of intraoperative MRI in neurosurgical procedures.

OBJECTIVE: We have worked in conjunction with scientists from the General Electric Corporation over 6 years to develop an open-bore MR imaging system (0.5 T) enabling optimal vertical access of surgeon and assistant to the patient, and real-time imaging during major neurosurgical procedures. METHODS: The intraoperative MR system (MRT) is located in a specially modified operative suite that combines the features of an MR-imaging suite with a fully functional operating room. An MR-compatible anesthesia machine and patient-monitoring device are located next to the magnet. The position of instruments, platforms and supports may be mapped in the operative field using 3 charge-coupled device video cameras mounted in the overhead support truncheon that follow various light-emitting diodes on the devices (Pixsys). The MR image plane can be defined as the axial, coronal or sagittal views through a point along the vector beneath the Pixsys tripod. A variety of surface coils were designed to take full advantage of full open patient access. The software, implemented by a technologist located outside the MR room, is now equivalent to that available on the commercial 0.5-tesla Signa Advantage system. Development of very robust 3-dimensional software in conjunction with the Surgical Planning Laboratory (SPL) at the Brigham & Women's Hospital is the subject of significant effort. The MRT system has been shown to possess imaging capabilities comparable, or even slightly superior (by 10%), to a conventional 0.5-tesla MR scanner. Two modified liquid-crystal display screens are mounted on the magnet housing for the surgeon to monitor the images during the procedures. Projection into larger screens or the operating microscope is under development. RESULTS: We have performed 110 neurosurgical cases in MRT as of January 29, 1997, including 47 biopsies, 6 catheter placements, 4 cyst drainages, 47 craniotomies for resection, 3 spinal cases (1 syrinx drainage), and 3 laser tumor ablations. CONCLUSIONS: MRT is especially useful in guiding biopsies and resections near cysts, ventricles and critical vascular structures where preoperative images with framed/frameless techniques would be inadequate to show anatomic changes during the procedure. Real-time images of a biopsy needle within the abnormal area are very useful in cases of subtle pathologic change. More complete resection of infiltrative tumor is readily accomplished. SPL image fusion of SPECT and neurofunctional data (e.g. from magnetic stimulation preoperatively) into the imaging space enables the surgeon to better visualize tumor invasion or neural function in real-time imaging during resection. Imaging of thermal gradients for cryoprobe or laser ablation, and combination with endoscopy and robotics will offer additional benefit in the performance of difficult neurosurgical procedures.

Biopsy↗
PubMed1990

Ablative neurosurgical procedures for the treatment of chronic pain.

This article is devoted to ablative neurosurgical procedures used for the treatment of chronic pain. The authors detail only those procedures that are currently performed. The procedures are classified as those directed to the peripheral nerves, spinal roots and cranial nerves; the dorsal root entry zone; the ascending extra-lemniscal pathways. The authors have analyzed the results of their own series and those published in the literature. They concentrate on the rationale and neurophysiological effects of the operations.

Chronic Disease↗
PubMed1983

Intracerebral hemorrhage remote from the site of the initial neurosurgical procedure.

Four cases of intracerebral hemorrhage remote from the site of the initial neurosurgical procedure are presented. Two of the four patients had preoperative hypertension. Possible mechanisms are discussed, and labile hypertension and unstable blood pressure during the perisurgical period may be contributory. Clinical awareness of this rare but potential complication is essential to early diagnosis and treatment. Difficulty in awakening from anesthesia and the development of new neurological deficits not attributable to the operative site are the most important keys to early diagnosis. Computed tomography is the diagnostic method of choice.

Adult↗
PubMed1997

Use of antiepileptic drugs in nontraumatic neurosurgical procedures. Is there any best route and time of administration?

We assessed in 15 consecutive patients the best route and time of administration for phenytoin (PHT) prophylaxis in neurosurgical procedures. We also correlated PHT levels in serum and cerebrospinal fluid after oral and parenteral loading doses. The mean PHT level was 13.9 micrograms/ml in serum and 2.03 micrograms/ml in cerebrospinal fluid (CSF), with a significant correlation between levels in both compartments (r = 0.73, p < 0.01). Mean PHT levels among the different groups were not statistically significant. We conclude that therapeutic levels of PHT in CSF can be achieved independently of the route of administration, as long as accepted loading doses are used.

Administration, Oral↗
PubMed1996

Changes in serum cytokine concentrations after neurosurgical procedures.

Cytokine responses to surgical trauma have been studied in 70 patients undergoing various neurosurgical procedures. Serum concentrations of interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), interleukin-8, (IL-8), tumour necrosis factor-alpha (TNF-alpha), and interferon-gamma (IFN-gamma) were measured before and after surgery using enzyme-linked immunosorbent assays. The serum concentrations of IL-1 beta, IL-8, TNF-alpha, and IFN-gamma did not change significantly following neurosurgical operations. In contrast, serum IL-6 levels were significantly elevated following surgery, peaking at postoperative day 1 and then gradually decreasing. Maximum IL-6 concentrations were considerably higher in patients who underwent surgery for brain tumours or aneurysms as compared with patients who had a ventriculoperitoneal shunt, neurovascular decompression or transsphenoidal adenomectomy. Intra-operative use of methylprednisolone, which is known to block the production and action of cytokines, suppressed the increase in IL-6 levels after surgery. There was a statistically significant correlation between the IL-6 peak concentration and the length of surgery in patients not treated with steroids, but not in patients treated with steroids. Additionally patients who underwent supratentorial surgery had higher peak concentrations of IL-6 than those who underwent infratentorial surgery. These results suggest that IL-6 is an early marker of tissue damage and may be useful in assessing the extent of postoperative stress.

Adolescent↗