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Iridoschisis and bilateral lens subluxation associated with periocular eczema.

We present a 53-year-old man with bilateral lens subluxation, unilateral iridoschisis, and a long-standing history of periocular eczema. Although a case of unilateral lens subluxation and ipsilateral iridoschisis has been described recently, the pathogenesis of this simultaneous occurrence remains unclear. Our case raises questions about the relationship among these clinical observations and suggests that these findings may exist as part of an unrecognized oculodermal syndrome.

Anterior Chamber↗

Bilateral lens subluxation associated with atopic eczema.

PURPOSE: Ectopia lentis remains a therapeutic challenge for ophthalmologists. It classically presents with a preceding history of blunt or penetrating ocular trauma, or it may be associated with other ocular disorders such as congenital glaucoma and aniridia, or concomitant hereditary systemic diseases such as Marfan syndrome and homocystinuria. METHODS: Case report. RESULTS: The authors describe a previously unreported mechanism of ocular trauma associated with continuous eye rubbing, resulting in bilateral recurrent subluxation of both intraocular lens and crystalline lens. CONCLUSIONS: It is useful for the ophthalmologist to be aware of this uncommon cause of ectopia lentis, since early advice and appropriate medical or surgical intervention may prevent more severe, sight-threatening complications.

Aged↗

Intralenticular bimanual irrigation: aspiration for subluxated lens in Marfan's syndrome.

We describe a new technique of aspiration of subluxated lens in young patients with Marfan's syndrome. Two small circular anterior capsulorhexis (1.5 mm to 2.0 mm) openings were created, and bimanual irrigation/aspiration was performed by introducing the irrigation cannula through 1 capsular opening and the aspiration cannula through the other. The irrigation cannula served the dual purpose of hydrating the lens matter and holding the lens in central position to ensure complete aspiration of the lens matter. The lens capsule was later removed and anterior vitrectomy performed by a vitrectomy cutter. This new technique of intralenticular irrigation/aspiration is effective and safe in performing lens aspiration in extensively dislocated crystalline lens in Marfan's syndrome.

Adolescent↗

Surgery of the hereditary subluxated lens in children.

PURPOSE: To describe the criteria and techniques for the surgery of hereditary subluxated lens in children and analyze the visual and surgical outcome after an extended period of follow-up. METHODS: From 1982 to 1994, 65 children who had subluxation of their lens were followed in the authors' clinic. Thirty-seven children (59 eyes) underwent surgery (27 eyes had Marfan syndrome; 23 eyes had essential dislocation; and 9 eyes had a diagnosis of homocystinuria, aniridia, microphthalmia, or Weill-Marchesani syndrome). The indications for surgery were best-corrected visual acuity of less than 20/70, forward sub-luxation of the lens to the anterior chamber, monocular diplopia, or rapidly progressing posterior subluxation of the lens. All 54 eyes with subluxation of the crystalline lens behind the iris underwent pars plana lensectomy combined with anterior vitrectomy. In five eyes with total forward dislocation of the lens in the anterior chamber, a limbal approach for removal of the lens and protruding vitreous was used. RESULTS: Postoperative follow-up ranged from 12 to 144 months (average, 55 months). After surgery, 522 eyes (88%) of the entire group achieved an improvement (2 lines or more on the Snellen chart) in best-corrected visual acuity. Seven eyes (12%) did not show improvement and remained with the same visual acuity as before the surgery. Retinal detachment was detected in one eye 2 years after surgery and was the only major postoperative complications observed in these patients. CONCLUSION: These results and the unique continuous and long-term follow-up on our patients demonstrate that lensectomy of ectopia lentis combined with anterior vitrectomy using a closed-system technique is a beneficial and relatively safe procedure.

Anterior Chamber↗

Iridoschisis associated with lens subluxation.

The etiopathogenesis of iridoschisis is unclear, although age-related degeneration and angle-closure glaucoma are its most common associations. We report the case of a 50-year-old man with lens subluxation (familial) in 1 eye and ipsilateral iridoschisis. The inferotemporal edge of the lens was directed anteriorly, pushing the iris forward; this led to iridoschisis and shallowing of the anterior chamber. The patient had bilateral angle-closure glaucoma. A subluxated lens rubbing against the iris may be a mechanical precipitating factor in the development of iridoschisis.

Glaucoma, Angle-Closure↗

Anterior axial lens subluxation, progressive myopia, and angle-closure glaucoma: recognition and treatment of atypical presentation of ectopia lentis.

PURPOSE: To describe the clinical features of an atypical presentation of ectopia lentis consisting of primary anterior axial lens subluxation in childhood, associated progressive myopia, and complicating angle-closure glaucoma; to facilitate early diagnosis of this triad; and to report the results of lensectomy for treatment. METHODS: A retrospective case review of eight patients. Clinical course, visual acuity, gonioscopy, axial length, refraction, fundus examination, associated systemic features, and results of treatment are provided. RESULTS: This subgroup of patients with ectopia lentis is at risk for progressive, synechial, angle-closure glaucoma. Identification of a clinical triad consisting of rapidly increasing myopia, normal axial length, and progressive axial subluxation leads to earlier diagnosis. Prophylactic lensectomy provides a safe and sight-saving treatment that arrests and, at times, reverses the progression of angle-closure glaucoma. CONCLUSIONS: Ectopia lentis with anterior axial subluxation and progressive myopia can be a sight-threatening condition when significant forward mobilization of the lens results in synechial angle-closure glaucoma. Recognition of this clinical entity can expedite diagnosis and prevent irreversible loss of vision secondary to glaucoma. Because the primary mechanism of angle closure is angle crowding, peripheral iridotomy does little to control the rise in intraocular pressure. Prophylactic lensectomy has proven to be the most reliable treatment in our experience.

Child↗

Bilateral megalocornea with unilateral lens subluxation.

Megalocornea refers to an enlarged cornea that measures 13 mm or more in horizontal diameter in the absence of raised intraocular pressure. We describe a five-month-old boy with bilateral megalocornea with unilateral lens subluxation. No other ophthalmological abnormality was present. In all previously reported cases with megalocornea and ectopia lentis, the lens was cataractous and the dislocation was in the inferior and posterior direction. In contrast, our case had a clear lens which was displaced superonasally.

Cornea↗

[Capsule contraction as a cause of in-the-bag intraocular lens subluxation and simplified technique of IOL reposition].

Presentation of the case of the pseudophakic patient in whom 3 months after uncomplicated phacoemulsification severe capsule contraction syndrome, followed by equatorial capsule fibrosis, 240 degree zonular dialysis, and spontaneous in-the-bag intraocular lens subluxation, were observed. Consecutive surgical intervention consisting of simplified transscleral "free haptic" through the capsule fixation and additional plastic of phimotic capsulorrhexis allowed to restore the best corrected visual acuity to 20/25.

Aged↗

Phacoemulsification using iris-hooks for capsular support in high myopic patient with subluxated lens and secondary angle closure glaucoma.

We report an unusual case of angle closure glaucoma in a 78-year-old highly myopic female patient. The patient did not show any preoperative signs of subluxation of lens. However, the capsular bag was noted to be unstable during surgery. The patient was managed with phacoemulsification of lens using a novel method of iris hooks for stabilization of capsular bag during surgery.

Aged↗

[Biomechanical characteristics of interactions between the drainage and accommodation regulatory systems of the eye in health and in contusion lens subluxation].

Biomechanical aspects of joint functioning of the accommodation system of the eye and the system regulating the discharge of intraocular fluid are considered proceeding from the concept of joint automated regulation. A multifunctional biomechanical model of the eye, created by the authors on the basis of numerous data and permitting them to quantitatively trace the relationships in the functions of the drainage and accommodation intraocular regulatory systems in health and in contusion subdislocation of the lens, is analyzed for various clinical situations. Theoretical and practical prerequisites for the development of novel methods for the diagnosis and treatment of primary open-angle and secondary phacotopic glaucoma are discussed, specifically, regulation of intraocular fluid discharge by purposeful shifting of the range of activity of the accommodation regulatory system. A detailed analysis of mutual functioning of the above ocular systems is practically important for clinical ophthalmology, for it accelerates the development of novel methods of diagnosis and pathogenetically-based therapy of a number of ocular diseases.

Accommodation, Ocular↗

Subluxated lens: phacoemulsification with iris hooks.

We describe a technique to manage subluxated cataracts with the use of 4 or 5 disposable nylon iris hooks placed on the capsulorhexis edge to support the lens and stabilize the capsular bag during phacoemulsification. The use of an endocapsular tension ring provides excellent centration of the capsular bag, enabling endocapsular intraocular lens (IOL) implantation. Sixteen eyes with zonular dialysis between 90 degrees and 180 degrees had surgery with this technique. The mean visual acuity significantly improved from 0.26 +/- 0.18 to 0.68 +/- 0.33 (P<.001). The surgeries were uneventful. Postoperative complications included cystoid macular edema 5 months after surgery in 1 eye and slight IOL dislocation with no symptoms detected 2 months after surgery in 4 eyes. The technique appears to be safe, ensuring a stable IOL with reduced surgical risks.

Aged↗