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PubMedDate not supplied

Etiologies of postgonococcal urethritis in homosexual and heterosexual men: roles of Chlamydia trachomatis and Ureaplasma urealyticum.

Before treatment for urethral gonorrhea, Chlamydia trachomatis was isolated from 18% and Ureaplasma urealyticum from 37% of 121 men. C. trachomatis was recovered from none of 18 homosexual men who had gonorrhea and from 22 of 95 heterosexual men who had gonorrhea (P less than 0.05). After treatment with a penicillin, postgonococcal urethritis occurred significantly more often in heterosexual than in homosexual men (P less than 0.002). Postgonococcal urethritis developed in all men from whom C. trachomatis was isolated. Among men without U. urealyticum infection, postgonococcal urethritis was significantly associated with C. trachomatis infection (P less than 0.02). Among men without C. trachomatis infection, postgonococcal urethritis was less closely associated with U. urealyticum infection (0.1 greater than P greater than 0.05). Postgonococcal urethritis was least frequent among men who had neither C. trachomatis nor U. urealyticum infection.

Chlamydia Infections↗
PubMed1976

Chlamydial infection of the male urethra.

Urethral specimens from 477 men were collected with endourethral swabs and examined for Chlamydia trachomatis by cell culture on McCoy cells pretreated with idoxuridine. Of these men, 141 had gonococcal urethritis, 262 non-gonococcal urethritis (NGU), and 74 showed no evidence of urethritis. Of 118 men with heterosexually acquired gonococcal urethritis, thirty (25 per cent.), and of 23 men with homosexually acquired gonococcal urethritis, five (22 per cent.), yielded C. trachomatis from the urethra. Urethral specimens from 240 heterosexual men with NGU were examined, and 118 (49 per cent.) yielded C. trachomatis. Of these 240 men, 140 gave a past history of gonococcal or nongonococcal urethritis and 67 (48 per cent.) of these were positive for C. trachomatis; no past history was given by 100 men, of whom 51 were positive for C. trachomatis. Of the 240 heterosexual men with NGU, 81 had had symptoms for 7 days or more before examination, of whom 48 (59 per cent.) yielded isolates of C. trachomatis, and 145 had had symptoms for less than 7 days, of whom 59 (41 per cent.) yielded isolates. Of fourteen asymptomatic men, three were positive for C. trachomatis. Of 22 homosexual men with NGU, seven (32 per cent.) yielded C. trachomatis. C. trachomatis was recovered from the urethra in three (5 per cent.) of sixty heterosexual men without urethritis, and none of fourteen homosexual men without urethritis yielded C. trachomatis.

Adult↗
PubMed1977

Anorectal gonococcal infection.

Anorectal gonococcal infection is common in women and homosexual men. In women with uncomplicated gonorrhea, the mean prevalence rate of anorectal involvement is 44%, with lone involvement of the anorectum in 4%. Among homosexual men with gonorrhea, anorectal infection occurs in 45%, although more than 90% of all male patients with anorectal gonorrhea admit to homosexual rectal intercourse. This infection is usually asymptomatic but occasionally presents with acute or chronic symptoms that mimic other causes of proctitis. Whereas currently recommended regimens for uncomplicated gonorrhea appear effective for anorectal gonorrhea in women, results in men have not been adequately evaluated. Available data showed failure rates from 7% to 35%; however, only one study used a currently accepted regimen. Further controlled studies in male patients with anorectal gonorrhea are clearly needed to establish optimal therapeutic regimens. Diligent contact tracing of all male homose.xual cases appears to be the only effective means of control at present.

Anti-Bacterial Agents↗
PubMedDate not supplied

Hormones and sexual differentiation of the brain.

Male rats castrated on the first day of life exhibited predominantly heterotypical (homosexual) behaviour after androgen substitution in adulthood. In addition, an increased evocability of a positive feedback effect of oestrogen was observed in such genetic males. In homosexual men, an increased evocability of a positive oestrogen feedback on luteinizing hormone (LH) secretion was also found as compared to heterosexual men. These findings suggest that male homosexuality may be based, at least in part, on andogen deficiency during a critical period of brain differentiation. In addition, we have found significantly increased plasma follicle-stimulating hormone (FSH) and LH levels associated with decreased plasma free testosterone levels in homosexual men, but only in effeminate homosexuals. In view of these data, sexual deviations in the human may be based, at least in part, on discrepancies between the genetic sex and a sex-specific sex-hormone level during brain differentiation in prenatal life. Methods were therefore developed for determining genetic sex and sex-specific sex-hormone level during brain differentiation in prenatal life. Methods were therefore developed for determining genetic sex and sex-specific sex-hormone levels in amniotic fluid, in order to detect and possibly correct such discrepancies. Sex hormone-dependent brain differentiation may be mediated, at least in part, by neurotransmitters, which may be regarded as local hormones of the brain. Interestingly enough, we have found permanent abnormalities of mating and other non-mating behaviour associated with permanent structural and chemical alterations in discrete brain regions of rats after neonatal treatment with psychotropic drugs known to affect neurotransmitter metabolism in the brain. Therefore, changes in neurotransmitter concentrations and/or turnover rates induced by psychosocial influences as well as by systemic hormones (particularly by sex hormones), when occurring during differentiation and maturation of the brain, may permanently affect sexual behaviour, sexual orientation and gender role behaviour throughout life.

Androgens↗
PubMedDate not supplied

Male homosexuality: perversion, deviation or variant?

Male homosexuality has complex determinants: biological, psychological, social, cultural and situational factors may be relevant, either inhibiting hetereosexuality or leading towards homosexuality. Environmental factors seem paramount, particularly significant early relationships, usually within the family. Especially implicated are the personalities and interaction of the parents, recent interest being especially in the father's role. Also relevant is the family as a complex social system and the modes of communication within it, both verbal and non-verbal. Social research and sociopolitical pressures have helped to liberalize attitudes to homosexually 'deviant' behaviour but have not added significantly to its understanding. Many factors are involved in determining whether homosexual men seek therapy and reach a particular therapist. These factors relate to the patient's and therapist's personalities; to different therapeutic philosophies and therapeutic goals; and to the formal and informal referral networks in society.

Freudian Theory↗
PubMed1978

The effect of luteinizing hormone releasing hormone (LRH) on pituitary gonadotropins in male homosexuals.

Basal serum LH and FSH values were found to be within normal limits in 9 homosexual men. The mean LH and FSH responses following the intravenous administration of 100 microgram of LRH were not significantly different from that of heterosexual controls. In addition, the mean basal plasma serum testosterone was similar in the two groups. There is thus no definite implication of endocrine factors in the genesis of male homosexuality.

Adult↗
PubMed1979

Heterosexual marriage of homosexual males: some associated factors.

Three matched groups of predominantly homosexual men were compared using Weinberg and Williams' questionnaire. Two of the groups contained men who were currently heterosexually married and men who had been heterosexually married; the third group was unmarried controls. Reasons for marriage were reviewed and found to be a combination of situational factors and, to a greater extent, of the expectations of those men who married of a more negative societal reaction against homosexuality. Implications of these findings for therapy are briefly discussed.

Evaluation Studies as Topic↗
PubMedDate not supplied

Venereal transmission of shigellosis in Seattle-King county.

In the past, shigellosis in Seattle-King County has been primarily a disease of children, their parients, and foreign travelers. During the 18 months beginning in July 1975, an outbreak of shigellosis in Seattle's community of gay men involved both Shigella flexneri and Shigella sonnei. They accounted for nearly 30% of all cases of shigellosis reported to the health department. Fellatio and/or oral-anal contact was reported by 90% of the infected homosexual men; this was probably the mechanism of transmission of most infections. Intercity spread was determined by case histories and by the finding of S. flexneri 3, a previously unusual organism in Seattle.

Dysentery, Bacillary↗
PubMedDate not supplied

Gonorrhea in the homosexual man: frequency of infection by culture site.

The aims of this study were determine the frequencies of infection with Neisseria gonorrhoeae at various sites in homosexual men who were attending clinics for treatment of sexually transmitted diseases in central Scotland and to appraise the diagnostic tests used. Specimens for culture were taken from the urethra, pharynx, and anorectum of every homosexual man in the study. When the first cultures of pharyngeal and rectal specimens were negative, these cultures were repeated twice at weekly intervals. The urethra was infected in 169 (60.8%), the anorectum in 114 (41.0%), and the pharynx in 23 (8.3%) of 278 patients who had gonorrhea. By reliance on only one set of tests, eight (7.0%) of 114 patients who had rectal gonorrhoea and six (26.1%) of 23 patients with pharyngeal infection would have been missed. The results indicate the importance of obtaining specimens for culture from all sites that might possibly be infected, regardless of the symptoms.

Adolescent↗
PubMed1979

Epidemic of amoebiasis and giardiasis in a biased population.

Of 126 homosexual men in a selected population in New York City, 31.7% were infected with Entamoeba histolytica, 18.3% with Giardia lamblia, and 39.7% with one or both on a single stool examination. Of 5885 clinic and hospital patients examined in the same laboratory by the same methods, 1.3% were infected with E. histolytica, 2.1% with G. lamblia, and 3.3% with one or both. Evidence indicates that an epidemic of intestinal protozoan infection exists in the homosexual male population in New York City. The difficulty in making a diagnosis, inadequate therapy, failure to alert potential victims, and official neglect of the epidemic have combined to create a dangerous situation.

Amebiasis↗
PubMed1978

Attitudes toward homosexuality and femininity in men.

College students were asked to express their liking for a male stimulus person who was described as either heterosexual or homosexual and as masculine or feminine. Subjects disliked the homosexual man more than the heterosexual man, regardless of his gender attributes. Subjects did not, however, consistently dislike the feminine man more than the masculine man. The feminine heterosexual man was liked less than the masculine heterosexual man, but the feminine homosexual man was liked more than the masculine homosexual man. These results cast doubt on earlier notions that homosexual people are disliked because of their presumed inappropriate gender attributes. Instead, it appears that homosexual men are disliked even more if they violate the feminine stereotype. Reasons for this effect are proposed.

Attitude↗
PubMed1978

"Personals" advertisements of lesbian women.

Based on a design adapted from previous content analyses of the "Personals" advertisements of heterosexual men and women and of homosexual men, advertisements for lesbian partners were studied in the light of predictions derived from exchange theory and from the findings of other studies of lesbianism. Lesbians' advertisements, as hypothesized, were found to emphasize positive characteristics and to de-emphasize the negative; to be more like those of nonlesbian women advertisers than like those of men of either sexual orientation; and to tend toward an androgynous style. Implications of these and other findings are discussed.

Adult↗
PubMed1979

Gay ghetto.

Gay people have claimed that there exist within major cities "gay ghettos", neighborhoods housing large numbers of homosexual men and women as well as gathering places where homosexual behavior is generally accepted, and have designated as such certain sections of Boston, New York, Chicago, San Francisco, and Los Angeles (Aiken, 1976, p. 27; Altman, 1971, p. 42; Brill, 1976, p. 27; Chicago Gay Liberation, 1970, pp. 3-4; Kantrowitz, 1975, p. 48; Nassberg, 1970, p. 1; Russo, 1976, p. 47; Shilts, 1977, p. 20; Whitmore, 1975, p. 45; Whittman, 1972, pp. 167-168). Sociologists have picked up the term, using it repeatedly in research (e.g., Humprheys, 1972a, pp. 80-81; Weinberg & Williams, 1974, p. 43). Typically, however, these authors offer no observations to support their use of the phrase. This paper analyzes the validity of "gay ghetto" as a sociological construct, limiting discussion to the male homosexual community.

Gender Identity↗
PubMedDate not supplied

Life-history interviews of aging gay men.

Homosexual men and women have seldom been studied by gerontologists and almost nothing is known about the lifestyles, pattern of development through the adult years, and the effect of homosexuality on aging. Fourteen gay men, ranging in age from fifty-five to eighty-one, were interviewed about their life history and experiences of aging as gay men. Three of the respondents had long-term relationships that lasted up to forty years; two had experienced the death of a lover and had begun a new long-term relationship; four had been married to women and two had children (one unmarried man adopted a son and is now a grandfather). The wide diversity of their patterns of aging, the presence of positive aspects of gay aging, and the high life satisfaction of many of the respondents contradict the stereotype of the lonely, isolated old gay man.

Aged↗
PubMed1977

Therapeutic regimens for anorectal gonococcal infection in males.

Anorectal gonococcal infection is particularly prevalent in women and homosexual men. Although the currently recommended Public Health Service therapeutic regimens for uncomplicated gonorrhea appear to be effective also for anorectal gonorrhea in women, their efficacy for anorectal infection in men has not been adequately evaluated. We report a case of gonococcal proctitis in a homosexual man that did not respond to therapy with ampicillin plus probenecid and tetracycline, but subsequently responded to spectinomycin therapy. Currently available therapeutic regimens for anorectal gonococcal infection in males are reviewed.

Adult↗
PubMed1975

Evocability of a slight positive oestrogen feedback action on LH secretion in castrated and oestrogen-primed men.

Orchidectomized heterosexual men suffering from prostatic cancer with suppressed serum LH values by oestrogen priming exhibited a slight, but significant surge of LH secretion following oestrogen injection. In contrast, orchidectomized and oestrogen-primed heterosexual men with unsuppressed serum LH levels as well as intact heterosexual men did not display any positive oestrogen feedback action on LH secretion, as it was observed in intact homosexual men.

Aged↗
PubMed1977

Examining the homosexual male for sexually transmitted diseases.

Homosexual men may be deterred from seeking an examination for sexually transmitted diseases because it would require an open admission of sexual preference. For these diseases to be controlled, gay men must be motivated to be examined for sexually transmitted diseases. If a medical or health professional feels unable to respond to a gay patient's needs, he should refer the patient to someone who deals well with gay patients. Health care services must be offered in a way that minimizes the anxiety many homosexuals associate with examination and treatment for sexually transmitted diseases.

Anxiety↗