Flea infestation and its control.
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Commensal rats and shrews were trapped from 47 fresh food markets in Bangkok during the two study periods in the same markets: 21st June to 28th December 1999 and 1st March to 31st May 2000. Trapping was performed using wire live traps on three consecutive nights in each period. The trapped animals were identified for taxonomic species and flea infestation. Fleas were collected, identified and counted. Four species of rodents: Rattus norvegicus, Rattus rattus, Rattus exulans and Mus musculus, and one species of shrew: Suncus murinus were trapped in comparable numbers during the two study periods. Among the 1177 animals trapped, 84.3 per cent were R. norvegicus. Regarding sex prevalence, a higher number of female animals were trapped compared to males. Almost all the fleas collected were Xenopsylla cheopis, and there were very few Ctenocephalidesfelis-felis. Flea index based on the number of X. cheopis was 0.65 for all over Bangkok. Based on the geographical area of Bangkok, the inner area had the highest rodent population and the highest flea index of 0.86. Therefore, the inner region should be the priority for sanitation improvement.
OBJECTIVE: To determine whether treatment with selamectin would reduce clinical signs of flea allergy dermatitis (FAD) in dogs and cats housed in flea-infested environments. DESIGN: Randomized controlled trial. ANIMALS: 22 dogs and 17 cats confirmed to have FAD. PROCEDURE: Animals were housed in carpeted pens capable of supporting the flea life cycle and infested with 100 fleas (Ctenocephalides felis) on days -13 and -2 and on alternate weeks with 10 to 20 fleas. On day 0, 11 dogs and 8 cats were treated with selamectin (6 mg/kg [2.7 mg/lb]). Dogs were retreated on day 30; cats were retreated on days 30 and 60. All animals were examined periodically for clinical signs of FAD. Flea counts were conducted at weekly intervals. RESULTS: Throughout the study, geometric mean flea counts exceeded 100 for control animals and were < or = 11 for selamectin-treated animals. Selamectin-treated cats had significant improvements in the severity of miliary lesions and scaling or crusting on days 42 and 84, compared with conditions on day -8, and in severity of excoriation on day 42. In contrast, control cats did not have any significant improvements in any of the clinical signs of FAD. Selamectin-treated dogs had significant improvements in all clinical signs on days 28 and 61, but in control dogs, severity of clinical signs of FAD was not significantly different from baseline severity at any time. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that topical administration of selamectin, even without the use of supplementary environmental control measures and with minimal therapeutic intervention, can reduce the severity of clinical signs of FAD in dogs and cats.
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The species of flea infesting pets and hedgehogs in Germany were investigated through a survey of small animal practitioners throughout the country who were asked to collect specimens at their veterinary practices. A total of 625 veterinarians/veterinary practices responded and provided 2445 intact anti identifiable flea specimens. These fleas originated from 294 dogs (795 fleas), 334 cats (1152 fleas), 76 hedgehogs (481 fleas), five domestic rabbits (10 fleas), one golden hamster (four fleas) and one ferret (three fleas). Dogs were found to be infested with Archaeopsylla erinacei, Chaetopsylla globiceps, Ctenocephalides canis, Ctenocephalides felis, Hystrichopsylla talpae, Nosopsyllus fasciatus, Paraceras melis and Pulex irritans. From cats, Archaeopsylla erinacei, Ceratophyllus gallinae, Ceratophyllus garei, Ctenocephalides felis, Ctenophthalmus assimilis, Hystrichopsylla talpae, Monopsyllus sciurorum, Nosopsyllus fasciatus, Spilopsyllus cuniculi and Typhloceras poppei were collected. In both dogs and cats the most prevalent species were Ctenocephalides felis (78.9% and 91.6%, respectively) and Archaeopsylla erinacei (21.1% and 12.6%, respectively) followed by Ctenocephalides canis in dogs (5.8%) and Hystrichopsylla talpae in cats (1.2%). The fleas isolated from rabbits were Ctenocephalides felis, Hystrichopsylla talpae and Spilopsyllus cuniculi. Nosopsyllus fasciatus and Ctenocephalides felis were recovered from the golden hamster and the ferret, respectively. The hedgehogs were found to be infested with Archaeopsylla erinacei, Ceratophyllus gallinae and Ctenocephalides felis.
From an ongoing country-wide study on the spectrum, the epidemiology and the population dynamics of flea infestations in dogs and cats, important preliminary results from the three areas of Karlsruhe, Nuernberg and Leipzig are presented. A total of 1922 dogs and 1838 cats from 12 different veterinary practices or clinics in three areas of Germany were systematically examined between July 2003 and June 2004. All dogs and cats appearing for a clinical veterinary consultation on one regular working day per month, per practice, were clinically examined. Dogs and cats were examined irrespective of any kind of prior therapeutic or prophylactic insecticidal treatment. The results show that a total of 99 dogs (5.13%) and 263 cats (14.33%) were infested. Cats were more often flea-infested than dogs (p < 0.05). The highest infestation rates for dogs (x = 7.87%) were detected between July and October, and for cats (x = 21.14%) between July and September, the lowest infestation rates for dogs (x = 2.88%) were observed between November and May, and for cats (x = 12.16%) between November and April (p < 0.05). Although the prevalences were generally higher during the summer months, no statistical differences were detectable when looking at the pattern between the four seasons, neither for dogs, nor for cats. Interestingly, the highest prevalences in dogs (9.9%) were detected in June 2004 and comparatively, in cats (23.86%) in August. The lowest detection rates in dogs were seen (1.28%) in April and in cats (7.26%) in January. The preliminary results did not indicate any tendency for a relationship between climatic conditions and flea infestation rates. Similarly, no differences of the infestations rates were detectable between urban and rural areas, 56% (dogs) and 46% (cats) of the infested pets originated from urban habitats. The flea species collected include Ctenocephalides felis, Ctenocephalides canis, Archaeopsylla erinacei, Pulex irritans, Ceratophyllus gallinae, etc. The overall frequencies reveal that C. felis was the most prominent species (81.5%), followed by C. canis (12.5%), A. erinacei (2.7%) and P. irritans (1.7%).
OBJECTIVE: To evaluate efficacy of a 9.1% (w/w) imidacloprid solution, applied topically, to remove fleas from dogs and the duration of residual flea control when dogs were exposed to continuing flea infestation. ANIMALS: 32 adult mixed-breed dogs. PROCEDURE: Dogs were allocated to 4 groups of 8 dogs each; dogs of 3 groups received a single dose of imidacloprid, and those of the fourth group received excipient. Each dog was infested with 100 adult fleas on study days -3, -1, 6, 13, 20, 27, and 33. Treatments were applied on day 0. Each dog was examined for live fleas on days -2, 1, 7, 14, 21, 28, and 34. Posttreatment efficacy was determined by comparing the mean number of live fleas remaining on the treated dogs with the mean number of live fleas remaining on the control dogs. RESULTS: All 3 imidacloprid dosages provided flea control > or = 96.9% one day after treatment. Maximal efficacy of all 3 dosages (99.1 to 100%) was observed at 7 days after treatment. Flea control with 3.75 mg of imidacloprid/kg of body weight ranged from 94.4 to 96.9% for days 14 to 28 and decreased to 91.6% by 34 days after treatment. Flea control with 7.5 and 10.0 mg of imidacloprid/kg was 97.8 to 100% through day 28. At day 34, dosages of 7.5 and 10.0 mg of imidacloprid/kg were 97.6 and 96.9% efficacious, respectively. CONCLUSION: 7.5 or 10.0 mg of imidacloprid/kg are equivalent and superior to 3.75 mg/kg for flea control over the course of a 34 day posttreatment period. CLINICAL RELEVANCE: Monthly imidacloprid application of 7.5 to 10 mg/kg will rapidly kill existing and reinfesting flea infestations on dogs and break the flea life cycle by killing adult fleas before egg production begins.
The objectives of the present study were to study the fauna of fleas infesting dairy goats in Greece, the spectrum of hosts each flea species infests, identify risk factors in the environment, and goat management practices that favour flea infestation of goats, and describe the seasonal variation of infestation in goats. For this purpose, a total of 64 herds, with a history of flea infestation in goats, were visited during June and July of 2002 for data collection on flea burdens, species of fleas on goats, and other farm or pet animal species in the farm. Also data were collected on herd characteristics and management along with the flea infestation status of the village where it was located through a questionnaire survey. Data on elevation and climatic characteristics of the villages where the herds were located were also used in the study. All fleas collected from goats, sheep, pigs, and cattle were identified as being Pulex irritans. All fleas collected from cats were identified as being Ctenocephalides felis. Dogs were infested either with P. irritans, C. canis, or C. felis, or with both C. canis and C. felis. Kids had a significantly higher flea burden than goats and the Skopelos breed had the highest flea burden of all breeds followed in diminishing order by the breeds Capra prisca, Saanen cross mix, and Alpine cross mix (p < 0.05). The gender of the animal had no significant effect on flea burden. Factors significantly affecting the flea burden of goats were duration of flea infestation in the herd, type of flea control, and manure imported prior to the appearance of fleas in the herd (p < 0.05). The flea burden of goats was highest during summer and lowest during winter (p < 0.01), with complete an absence of infestation in January and February. Finally, a significant difference (p < 0.05) was found between the average annual temperature of villages with flea infestation (15.59 degrees C) and villages without flea infestation (17.14 degrees C). It was concluded that P. irritans was a true infestation of goats in Greece.
A study of Ctenocephalides felis strongylus and of its effect on the performance of sheep and goats was made. Fleas showed more affinity for sheep than goats. There was a high concentration between lamb and kid mortality and the degree of flea infestation. The clinical effects of flea infestation are highlighted. The factors responsible for flea infestation and its control are discussed.
Seroprevalence of Bartonella henselae, Toxoplasma gondii, feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infections was investigated in 1,447 domestic cats derived from the north (Hokkaido) to the south (Okinawa) prefectures in Japan. Of the cats investigated, 8.8% (128/1,447) were seropositive to B. henselae, 5.4% (78/1,447) to T. gondii, 9.8% (107/1,088) to FIV, and 2.9% (32/1,088) to FeLV, respectively. For B. henselae infection, the positive rate varied from 11.5% in cats of 1 to <2 years old to 7.2% in those over 3 years old. Outdoor cats showed higher positive rate (14.5%) than that (7.0%) in indoor ones. The rate (13.5%) in flea-infested cats was significantly higher than that (7.4%) in flea-negative cats. The positive rates in southern and urban sites were more likely to be higher than those in northern and suburban sites, suggesting that warm and humid environments, density of cat population, and raising status, including hygienic condition and flea infestation in cats may correlate to higher seroprevalence of B. henselae infection. For T. gondii, FIV and FeLV infections, the seroprevalence also tended to be higher in outdoor, flea-infested cats and advanced age groups. For FIV infection, the positive rates in male (14.3%) and outdoor cats (15.0%) were significantly higher than those in female (5.0%) and indoor cats (4.6%). On the other hand, no significant difference in seropositivities was observed in FeLV and T. gondii infections concerning to both genders and raising status.
Parasitism by the flea Synosternus cleopatrae does not affect the body mass of its principal rodent host, Gerbillus andersoni under natural infestation levels. We hypothesized that the lack of negative effects of flea parasitism on rodent body mass could be related either to the low level of natural infestation or to the differential susceptibility of rodent age cohorts to flea parasitism. We tested these hypotheses by measuring body mass change under flea parasitism in (a) adult rodents infested with fleas above the natural infestation level (the first hypothesis) and (b) juvenile rodents infested with fleas at natural infestation levels (the second hypothesis). Adult individuals parasitized by a number of fleas higher than in nature lost body mass at higher rates than non-parasitized control individuals. Parasitism significantly affected daily body mass change of juvenile gerbils. Juvenile rodents parasitized by fleas at the natural level of infestation lost body mass faster and gained body mass slower than control animals. We suggest that some regulating mechanisms may limit natural flea densities at a point at which the negative effect on hosts is below the accuracy of our measurements. However, natural flea densities are sufficiently high to harm the more susceptible, juvenile cohort.
Two controlled and masked multi-centre studies were conducted to examine the efficacy of a novel topical avermectin, selamectin, against natural flea infestations on 418 dogs and 345 cats. Veterinary patients with viable flea infestations were enrolled in the studies, which were conducted in United Kingdom, France, Germany, and Italy. Animals were allocated randomly in a 2:1 ratio to one of two treatments: either selamectin alone at a minimum dosage of 6mgkg(-1) or fenthion at recommended dose rates. Concurrent use of an environmental spray (containing methoprene and either pyrethrins or permethrin) was permitted only for fenthion-treated animals. In-contact cats and dogs (animals living in the same home) received the same treatment as the first animal enrolled from the household, if recommended by the veterinarian. Study day 0 was defined as the day of first treatment. Animals were treated on days 0, 30, and 60, and flea comb counts and clinical evaluations were conducted on days 0, 14, 30, 60, and 90. Analysis of variance of ln(flea count+1) showed that values were significantly lower for selamectin alone compared with fenthion (with or without the concurrent use of an environmental spray) in dogs on days 30, 60, and 90 (P<0.05) and in cats on days 14, 30, 60, and 90 (P<0.01). For selamectin, the reductions in geometric mean flea counts on days 14, 30, 60, and 90, compared with day 0, were 92.5, 90.7, 98.1, and 99.1%, respectively, for dogs and 92.8, 92.7, 97.7, and 98.4%, respectively, for cats. Selamectin was shown to be safe and highly effective in the control of naturally acquired flea infestations on dogs and cats presented as veterinary patients in Europe.
Oral grooming is common in cats, as in rodent and bovid species where grooming has been shown to be effective in removing lice and ticks. In Experiment 1, we examined the effectiveness of oral grooming in removing fleas which are the main ectoparasite of cats. Elizabethan collars (E-collars) which prevented grooming were fitted on nine cats in a flea-infested household and 3 weeks later, flea numbers on these cats were compared with nine control cats in the same household. Flea numbers dropped in the control cats reflecting an apparent drop in adult fleas in the environment, but in the E-collar cats, flea numbers did not drop, and were about twice as numerous as in control cats. The significantly greater number of fleas on the E-collar cats was attributed to their inability to groom off fleas. In Experiment 2, videotaping of nine different cats from the flea-infested household revealed that these cats groomed at about twice the rate of 10 similarly videotaped control cats from a flea-free colony. These results reveal that flea exposure can increase grooming rate in cats and that grooming is effective in removing fleas.