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[Filiation hamartoma polyposis dysplasia and small bowel adenocarcinoma].

Peutz-Jeghers syndrome is a hereditary affection with dominant autosomal transmission. The risk of cancerisation is largely higher than that in the general population. Dysplasia is rare. Transformation of the polyposis hamartoma into a site of dysplasia then into adenocarcinoma has been rarely reported. The authors report the case of a 14 year-old patient, having a severe dysplasia on ileal polyposis hamartoma related to the syndrome of Peutz-Jeghers.

Adenocarcinoma↗

[When continuity is told to us. Mental health and symbolization of filiation in aged persons].

The author examines the links between the feeling of continuity and the mental health of 25 elderly people who recount their perception of how material and cultural values are transmitted in their line of descendants and in their social community. In considering the aging process as a cultural system, the author builds a model depicting the symbolization of the rule of filiality, for which there are three categories developed in function of manifestations of a more or less strong feeling of continuity or of a feeling of rupture. Beyond their psychological vulnerability and the "deadline" to which they are confronted, these people find themselves in one of the three categories of this model through their relationships with their ascendants and descendants.

Aged↗

[Deoxyribonucleic acid (DNA) in tests of filiation, paternity and forensic medicine].

A new precise method of personal identification with significant implications for civil and criminal paternity cases, as well as for other forensic purposes and genetic studies is presented. DNA multi-locus analysis offers a discrimination of 1 in 30 billions, constituting the most precise determination in paternity testing. If we consider that the world population is around 5 billion people, and that less than 2.5 billions are males, of the which approximately 1/3 are not adults, then we can see how the possibility of error is extremely low. It makes other paternity studies with HLA, blood groups, enzymes and proteins ineffective in paternity disputes. All courts and legal personnel should be aware of the scientific implications of this new available test in our media.

Blood Group Antigens↗

[Familial psychosis and filiation].

Since the last decade of the nineteenth century, psychiatric nosology has been dominated by Kraepelin's binary system: the notion that the distinction between manic-depressive illness and schizophrenia identifies two separate diseases with differing symptom patterns and outcomes. However, Kraepelin recognised that intermediate states, as exemplified by Kasanin's concept of "schizoaffective" illness are common. In contrast to Kraepelin's separation of manic-depressive illness from schizophrenia, the concept of a continuum of psychosis implies that there are gradations of illness between unipolar depressive, through bipolar affective and schizoaffective illness, to schizophrenia. This concept is strongly supported by the majority of family studies. Moreover, no simple clinical demarcations of affective from schizophrenic illnesses can be made. The family findings are compatible with the hypothesis that the same gene or genes contribute to susceptibility to both schizophrenia and affective disorder: a single locus that may be variable between generations, and that is represented by homologous loci on the X and Y chromosomes.

Aged↗