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[Cytogenetic alterations in field workers routinely exposed to pesticides in Bogota flowers farms].

Frequency of cytogenetic alterations (micronuclei and chromosome aberrations), DNA repair deficiencies and acetylcholinesterase activity was determined for field workers in Bogotá, Colombia. These workers were regularly exposed to organophosphate and carbamate insecticides while employed on farms for flower growing. Interviews were conducted with 31 workers associated with occupational risk of pesticides exposure and 30 without exposure. A standard cytogenetic assay was used to determine chromosome aberrations and micronuclei frequencies. In addition, a challenge assay assessed response to gamma-rays as an indication of DNA repair deficiencies--cells were exposed to gamma-rays in vitro and the frequencies of chromosome aberrations in post-irradiation metaphase cells were quantified. The data were evaluated for percentage of aberrant cells, cells with chromosome aberrations and frequencies of chromatid breaks per 100 metaphase cells in each worker. The exposed group had a significantly higher frequency of cells with chromosome aberrations and micronuclei as compared with the non-exposed group (p = 0.02). However, the challenge assay did not indicate a significant difference (p > 0.1). These findings require confirmation by further analytical studies involving larger sample. Cytogenetic and toxicological studies, in conjunction with thorough clinical examination are recommended.

Acetylcholinesterase↗

Violence and threats of violence experienced by public health field-workers.

CONTEXT: Public health workers may work with clients whose behaviors are risks for both infectious disease and violence. OBJECTIVE: To assess frequency of violent threats and incidents experienced by public health workers and risk factors associated with incidents. DESIGN: Anonymous, self-administered questionnaires. SETTING: Texas sexually transmitted disease (STD), human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS), and tuberculosis (TB) programs. PARTICIPANTS: Questionnaires were completed by 364 (95.5%) of 381 public health workers assigned to the programs. The STD program employed 131 workers (36%), the HIV/AIDS program, 121 workers (33%), and the TB program, 112 workers (31%). MAIN OUTCOME MEASURES: The frequencies with which workers had ever experienced (while on the job) verbal threats, weapon threats, physical attacks, and rape, and risk factors associated with those outcomes. RESULTS: A total of 139 (38%) of 364 workers reported 611 violent incidents. Verbal threats were reported by 136 workers (37%), weapon threats by 45 (12%), physical attacks by 14 (4%), and rape by 3 (1%). Five workers (1%) carried guns and/or knives while working. In multiple logistic regression, receipt of verbal threats was associated with worker's male sex (odds ratio [OR], 2.4; 95% confidence interval [CI], 1.5-4.0), white ethnicity (OR, 2.4; 95% CI, 1.4-4.1), experience of 5 years or longer (OR, 2.2; 95% CI, 1.3-3.8), weekend work (OR, 1.8; 95% CI, 1.1-3.1), and sexual remarks made to the worker by clients (OR, 2.0; 95% CI, 1.2-3.5). Receipt of weapon threats was associated with worker's male sex (OR, 5.7; 95% CI, 2.4-15.3), white ethnicity (OR, 4.0; 95% CI, 1.8-9.3), age of 40 years or older (OR, 2.5; 95% CI, 1.1-5.8), work experience of 5 years or longer (OR, 2.7; 95% CI, 1.2-6.0), rural work (OR, 3.6; 95% CI, 1.3-10.1), being alone with the opposite sex (OR, 3.7; 95% CI, 1.6-9.7), and interaction with homeless clients (OR, 5.2; 95% CI, 1.7-18.8). Physical attacks were associated with sexual remarks made to the worker by clients (OR, 4.2; 95% CI, 1.4-13.9). No risk factors predicting rape were identified. CONCLUSIONS: Violence directed toward public field-workers is a common occupational hazard. An assessment of what situations, clients, and locations pose the risk of violence to public health workers is needed.

Adult↗

Methyl bromide intoxication in four field-workers during removal of soil fumigation sheets.

Methyl bromide is a highly toxic and penetrating compound used extensively as an insecticide for dry foodstuffs and as a soil fumigant (in greenhouses and fields) for the control of nematodes, fungi, and weeds. More than 300 cases of systemic poisoning and 60 fatalities attributable to methyl bromide have been reported [Alexeeff and Kilgore, 1983], resulting in substantial regulations concerning its handling, storage, application, and disposal. A recent exposure incident at a Connecticut nursery represents to our knowledge the first report of toxicity stemming from exposures in the field during removal of plastic sheets days after injection of methyl bromide into soil. Following removal of polyethylene sheets covering soil fumigated with methyl bromide, four field-workers developed fatigue and light-headedness and 3 workers noted progressive respiratory, gastrointestinal (GI), and neurologic symptoms. The acute systemic symptoms improved over several days, but later-onset neuropsychiatric symptoms persisted for several weeks. This incident stresses the need for improved worker education and strict adherence to safety precautions during all stages of methyl bromide fumigation and raises the possibility of an increased risk of toxicity associated with methyl bromide fumigation during a cool season.

Adult↗

Ornithonyssus (Acari: Macronyssidae) mite dermatitis in poultry field-workers in Almarg, Qalyobiya governorate.

Cutaneous manifestations of bird and rat mite infestation in man are not easily recognized by physicians or patients. Clinical signs and symptoms are developed secondary to bites of mites that have infested rats, domestic poultry or birds nesting in or near human habitation and comes into contact with man. This study details 4 cases of pruritic dermatitis developed in four field workers in poultry farms in Al-Marg district, Qalyobia governorate, Egypt. The zoonotic species of Ornithoyssus sp., (Family Macronyssidae) was isolated from all samples collected from patients' habitat and the role played by Ornithonyssus mites in causing dermatitis in man was discussed.

Acari↗

Chromosomal aberrations in peripheral lymphocytes of cotton field workers exposed to pesticides.

Fifty-two pesticide sprayers in cotton fields were selected for the analysis of chromosomal aberrations in peripheral lymphocytes. Twenty-five samples were collected from healthy males who were not exposed to pesticides. Statistical analysis revealed that there was a significant increase in chromosomal aberrations in the exposed population compared to controls. Total chromosomal aberrations increased irrespective of duration of exposure.

Adult↗

Persistence of symptoms after mild to moderate acute organophosphate poisoning among 19 farm field workers.

Exposure to 2 organophosphate pesticides occurred when entry into a cauliflower field was permitted 4 h after application of highly toxic chemicals. It resulted in acute illness of mild to moderate degree in 19 farm workers, including 3 children and 1 pregnant woman. There were no fatalities. Two to three months were required for recovery from major symptoms and return to normal acetylcholinesterase levels. An exception was the persistence of eye symptoms in the majority 4 mo after the day of exposure.

Adolescent↗

A comparative study of pesticide exposures in adults and youth migrant field workers.

To study possible differences between pesticide exposures received by youth (subjects less than 16 yr of age) and adults (subjects greater than 16 yr of age), human exposure samples (gloves and urine) were collected during the onion harvesting season of 1982. Environmental samples (soil, foliage, and field air) were also collected during the study period. All samples were analyzed for toxaphene, ethyl parathion, methyl parathion, and malathion. Environmental samples were found to have very low levels of these insecticides. The youth cohort had lower residue values than did the adults, and these differences were statistically significant (P less than 05) for toxaphene residues on gloves on each sampling day, and for ethyl parathion residues on gloves on one sampling day only. Detectable levels of dialkyl phosphates were found in only 2 of 44 urine samples.

Adolescent↗

A field worker's guide to a nutritional status survey.

This guide has been prepared specifically for the medical worker in a developing country who has little experience for survey methodology and few outside sources on which to draw. All, or only portions of the guide, may be used as local needs dictate. It provides an outline of necessary preparations, sampling, field organization, measuring techniques and recording form. To aid the statistical treatment and presentation of the data, a sample recording form is given together with coding instructions and output table layout.

Adolescent↗

Exposure of field workers to organophosphorus insecticides: sweet corn and peaches.

Plasma and red blood cell cholinesterase levels of professional agricultural workers engaged in packing sweet corn and thinning peaches were monitored. Workers with extensive contact with mechanically harvested sweet corn (the corn had been treated one or two days before harvest with a combination of ethyl and methyl parathion) exhibited significant depression of cholinesterase. Gloves, worn by 40% of the workers, provided some protection from absorption of pesticide residues. No significant cholinesterase depression was found in workers thinning peaches which had been previously treated with parathion.

Adult↗

Exposure of field workers to organophosphorus insecticides: cotton.

The red blood cell and plasma cholinesterase (ChE) levels of cotton scouts inspecting foliage for insect infestation and damage were monitored. Group means for ChE activity were significantly depressed at one or more time(s) during four of the eight growing seasons studied. Although no symptoms of organophosphate poisoning were confirmed, several scouts exhibited ChE depressions over 50% of pre-exposure levels.

Agricultural Workers' Diseases↗