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[Anaemia in two infants due to fetomaternal transfusion].

In two neonates, a boy suffering from persistent pulmonary hypertension of the newborn and a girl with fetal distress, massive fetomaternal haemorrhage was diagnosed (290 ml). In both cases fetal monitoring showed a sinusoidal heart rate pattern and the Kleihauer-Betke test was positive. Both children were intubated and ventilated and were given an erythrocyte transfusion. They both recovered. Differentiation between acute and chronic fetomaternal haemorrhage is essential when deciding on treatment: blood transfusion in acute fetomaternal haemorrhage and exchange transfusion in chronic fetomaternal haemorrhage with normoor hypervolemia. Differentiation is difficult. Little is known about the prognosis of fetomaternal haemorrhage. Because of the nature of perinatal problems and the possibility of neurological damage, long-term follow-up is recommended.

Adult↗

[Severe neonatal anemia associated with fetomaternal transfusion and persistent fetal circulation].

A newborn infant with massive fetomaternal hemorrhage is reported. The fetal blood loss led to severe late decelerations in the antepartal CTG. The newborn showed a marked anemia (Hb 4.9 g%!) and a rapidly progressive heart failure. Despite blood transfusions and digoxin therapy the infant developed the symptoms of a "persistent fetal circulation". This mechanism may have been responsible for the lethal outcome in other reported cases. A successful therapeutic approach adaptable to the different stages of severity of this dangerous perinatal condition is outlined.

Acute Disease↗