[Changes in the fundus oculi in shock].
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Long (for more than 17 years) therapy of 2331 patients (3122 eyes) with vascular conditions of the fundus oculi by a retinotropic drug solcoseryl showed its high efficacy as a monotherapy and in complex with other traditional and symptomatic treatments. Solcoseryl improved the visual function and hemodynamics of retinal vessels, promoted a more stable and longer stabilization of the treatment results, and accelerated the rehabilitation of patients.
Fluorescein-angiographic examination of fundus oculi in 33 patients with the syndrome of malignant hypertension made it possible to recognize for the first time changes in the choriocapillary layer, which in 29 patients were displayed by choroidal retention; ischemic zones were seen in 20 patients. It is suggested that the discovery of ischemic zones in the choriocapillary layer may be an early diagnostic criterion of malignant hypertension.
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The authors analyze the findings of clinical and morphologic studies of the pathologic changes in fundus oculi tissues of 3 patients who died with senile macular dystrophy, examined in life time by ophthalmoscopic technique with transformed light. The sclera, vascular coating, retina, macula retinae, optic nerve region were thoroughly studied with the use of review histological, histochemical methods, selective test for amyloid, thiazine red fluorescent histochemical method, and thioflavin T fluorescence. In 2 of the 3 cases amyloid degeneration in the presence of amyloid deposits in choroid vessels, arterial plexus vessels round the optic nerve presence of amyloid deposits in choroid vessels, arterial plexus vessels round the optic nerve orifice, in Bruch's membrane and in the sclera. Retinal vessels, optic nerve and its coatings were intact. Further investigations are to follow.
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A total of 100 patients (200 eyes) with cervical osteochondrosis were examined. Microcirculatory bed of the bulbar conjunctiva, pressure in the central retinal artery, and diameter of vessels in the fundus oculi were assessed. All these parameters were disordered in the examinees in comparison with normal controls. The degree of changes inversely correlated with clinical manifestations of cervical osteochondrosis. Study of ocular hemodynamics in this patient population helps predict the time course of the underlying disease.
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