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PubMed1986

Circulating gastrointestinal hormones in patients with flatulent dyspepsia, with and without gallbladder disease.

Fasting and post-prandial circulating levels of insulin, gastrin, gastric inhibitory polypeptide, pancreatic polypeptide and neurotensin were measured in patients with flatulent dyspepsia, with and without gallbladder disease and post-cholecystectomy. Levels were also measured in non-dyspeptic patients with gallbladder disease and normal controls. There were no consistent significant differences from controls for fasting and post-prandial responses in patients with a history of dyspepsia or those who experienced dyspepsia at the time of the test. In patients with gallbladder disease, with and without dyspepsia, there was a reduced neurotensin response compared to normal controls. It is concluded that circulating levels of these hormones are not related to symptoms of flatulent dyspepsia.

Dyspepsia↗

PubMed2001

[The domestic processing of the common bean resulted in a reduction in the phytates and tannins antinutritional factors, in the starch content and in the raffinose, stachiose and verbascose flatulence factors].

The objective of this study was to evaluate the effect of the soaking step and the domestic processing of the common bean, on the chemical composition, the levels of phytate, tannin, starch and flatulence factors by utilizing the follows treatments: raw bean (FC), freeze-dried cooked unsoaked bean (FCSM), freeze-dried cooked bean without the non-absorbed soaking water (FCSAM), freeze-dried cooked bean with the non-absorbed soaking water (FCCAM) and the soaking water (AM). The beans were soaking for a period for 16 hours in the proportion 3:1 (water:beans) at room temperature. The effect of the phytates and tannins on the net protein efficiency ratio (NPR) and protein digestibility using male Wistar rats were studied. A decrease in the phytate content of the beans (85%) with use of soaking was observed. In the case of the tannin content, only the cooking of the beans promoted high decomposition (84%). In the (FCSAM) treatment a decrease in the raffinose (25.0%), stachiose (24.8%), verbascose (41.7%) and starch (26.8%) contents was observed. Diets containing casein (control), casein plus the soluble solids obtain from the soaking water showed no significant difference (p > 0.05) for the NPR, as well as for the different bean treatments, although these showing lower values. The treatment (FCSM) showed the higher digestibility (74.3 +/- 5.8%) of the bean treatments, the casein diets showing 94.6 +/- 0.9%. The reduction of the phytates, tannin, starch contents and flatulence factors in the common bean was most effective when the soaking water not absorbed was discarded (FCSAM).

Animals↗

PubMed1987

Psychologic aspects of flatulent dyspepsia.

Psychologic and social factors have been implicated in the aetiology of dyspepsia. In this study these factors were investigated in relation to flatulent dyspepsia, a symptom complex that has traditionally been associated with gallbladder disease. Subjects completed the Middlesex Hospital Questionnaire and the Life Events Inventory and were interviewed in detail, using a semi-structured format. Three groups of patients with flatulent dyspepsia--those with and without gallbladder disease and post-cholecystectomy--all had significantly more associated somatic symptoms than non-dyspeptic subjects with gallbladder disease or normal controls, thus indicating greater emotional upset amongst dyspeptic patients. There was little evidence that symptoms were related to stressful life events.

Adult↗

PubMedDate not supplied

Flatulent dyspepsia: a tiered symptom complex?

The symptom complex of flatulent dyspepsia is ill-defined but is made up of at least nine individual symptoms. The relationship between these symptoms is not known and thier change after cholecystectomy in gall-stone patients is unpredictable; they disappear completely in less than half the patients. We studied the symptoms in one hundred and thirty nine patients, using various computer programmes to see if the changes after operation could be predicted and if some of the symptoms were linked or formed "clusters". The results did not show any standard relationship between the symptoms. We have therefore, proposed the hypothesis of a tiered symptom complex to explain these observations. They could be produced by a motility disorder affecting different parts of the gastro-intestinal tract to a varying degree.

Cholecystectomy↗

PubMed1971

Controlled trial of metoclopramide in the treatment of flatulent dyspepsia.

A double-blind cross-over trial of metoclopramide (Maxolon) against placebo was undertaken in 42 patients with flatulent dyspepsia. A highly significant difference was found in favour of the active drug (P<0.01). The time at which the drug is given in relation to the meal and onset of symptoms is probably important. It is concluded that metoclopramide is effective in the short-term treatment of these symptoms but should be started only after thorough investigations have excluded more serious disease.

Adolescent↗

PubMed1987

Gastric emptying in patients with flatulent dyspepsia, with and without gallbladder disease.

It has been suggested that the symptoms of flatulent dyspepsia are caused by a functional disturbance of the upper gastrointestinal tract. The aim of this study was to investigate delayed gastric emptying as the basis of symptoms in patients with and without gallbladder disease and after cholecystectomy. There were 13 dyspeptic patients with gallbladder disease, 12 with normal gallbladders, and 13 post-cholecystectomy patients. Gastric emptying was measured by means of a 99mTc-labelled scrambled egg meal and external scintillation counter. The rate of emptying in the symptomatic groups was compared with that in 24 asymptomatic normal control subjects and 12 non-dyspeptic patients with gallbladder disease. Delayed gastric emptying tended to occur in patients with gallbladder disease with and without dyspepsia and was not specifically associated with symptoms.

Adult↗

PubMed1997

Belching, bloating, and flatulence. How to help patients who have troublesome abdominal gas.

Gaseous belching, bloating, and flatulence are common complaints. These symptoms may herald the onset of important and treatable gastrointestinal diseases or may represent functional bowel disorders. The clinical challenge is to identify a cause so as to exclude serious gastrointestinal diseases and provide symptomatic relief. Detailed history taking and examination provide the basis for appropriate testing that may provide vital clues. Among otherwise healthy patients, intolerance to lactose or other food items is a common source of symptoms. This cause can be evaluated noninvasively using the breath hydrogen test. A clear understanding of the underlying pathophysiology paves the way for a rational approach to treatment, such as withdrawal of an offending food item, enzyme supplementation, simple reassurance, or psychotherapy.

Colonic Diseases, Functional↗

PubMedDate not supplied

[Flatulence].

At present physicians focus their medicine studies in well defined illnesses as peptic ulcer, gastric cancer, ulcerative colitis and so on. However, patients reveal their discomfort to us, that is their symptoms or group of symptoms (syndromes). For this reason, our concern for many years has been the study of symptoms and syndromes. In this review we will be looking at the concepts and information gathered with respect to intestinal gases, clinically known as flatulence.

Abdominal Pain↗

PubMed2003

[Indifferentiated rheumatism and/or epileptic flatulence].

A clinical case study of a 50 year-old woman brought to the Rhematology Department is presented, who showed clinical dry syndrome with immune disorders (not currently defined) and developed tumors (benign at present) and analytical autoimmunity with positive antitopoisomerase type I (formerly Scl70) confirmed. The clinical case is commented and the metheorism causes are discussed, among it, a possible variation of abdominal epilepsy as ictal flatulence, secondary to a meningioma of the right brain convexity.

Electroencephalography↗

PubMed1998

[Abdominal pain and flatulence. Intestinal and pulmonary tuberculosis. IgG kappa paraproteinemia].

A 21-year-old woman suffered from cramplike abdominal pain, flatulence and occasional diarrhoea for about one year. Over the past few weeks the abdominal symptoms exacerbated, besides productive cough and subfebrile temperatures developed. Coloscopy revealed two isolated, short ulcers in the proximal colon. The histological examination of the biopsies taken from these ulcers indicated granulomatous inflammation. Moreover small acinar infiltrates in both pulmonary apices were visualized. The findings in this patient originating from Turkey were suspicious for intestinal and pulmonary tuberculosis. Though sensitive methods were used (Ziehl-Neelson stam, amplified M. tuberculosis direct test, a polymerase chain reaction) direct tests allowed no detection of mycobacteria. Antituberculous therapy was initiated on a probatory basis to which the patient responded well and promptly. The diagnosis was confirmed by culture results: M. tuberculosis was grown from colonic biopsies, morning sputa and bronchioalveolar lavage.

Abdominal Pain↗

PubMed1964