[Interrelation of radioisotopic examination of patients with eye neoplasms and sources of possible errors].
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The use of polymer gel makes it possible to measure three-dimensional dose distributions of ionizing radiation. Phantoms with BANG-1 and BANG-3 gel were irradiated using a 68 MeV proton beam at the eye tumour therapy beam line of the Hahn Meitner Institute in Berlin. Up to twelve treatment fields could be applied to one gel phantom. The investigations consisted of mono-energetic Bragg curves, spread-out Bragg curves of circular fields (diameter 20 mm), and spread-out Bragg curves of patient fields. Magnetic resonance imaging was used to obtain the gel dose distributions. The results were compared to measurements of a water-phantom ionization chamber. The BANG polymer gels showed a significant quenching of Bragg peaks compared to ionization chamber measurements. The BANG-3 gel was found to be unsuitable for further investigations with 68 MeV protons. The use of BANG-1 allowed the verification of wedge slopes and irregular field forms. On the basis of our experience, polymer gels are well suited for quality assurance in proton therapy in principle.
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The paper presents the results of the observations of 81 patients among 84 (44 females and 40 males, aged 0 to 18 years) treated in the period 1990-1993 for neoplasms of the visual system. Surgery was performed in 73 of them (89%). Histopathological examinations of tumors define most of them as benign (96% and 4%) as primary malignant.
The difficulty in the choice of the optimal treatment strategy is explained by a great variety of the cellular composition, site, size, type, and growth rate of tumors of the eyelids, conjunctiva, cornea, and lacrimal duct; a good choice of effective treatment modalities, such as surgical or laser excision, ionization, cold or coagulation destruction does not simplify this task. The author suggests an algorithm, facilitating the choice of the treatment strategy, with due consideration for some specific features of each case.
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Metastatic neoplasms of the eye ball and their clinical picture, diagnosis, treatment and prognosis and discussed.
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