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PubMed1986

Effect of obesity on erythrocyte count and hemoglobin levels in Libyan diabetic patients.

Fasting blood glucose, erythrocyte count and hemoglobin levels of obese and nonobese Libyan diabetic women were determined. The mean values of fasting blood glucose, erythrocyte count and hemoglobin of obese diabetic women were 209.55 +/- 8.85 mg/dl, 4.986 +/- 0.04 X 10(6)/mm3 and 14.51 +/- 0.18 g/dl. The respective values for nonobese diabetic women were 243.47 +/- 12.56 mg/dl, 4.865 +/- 0.06 X 10(6)/mm3 and 14.31 +/- 0.19 g/dl. The mean values of the three variables of obese patients were significantly different from those of the nonobese patients. Statistically significant correlations were found between fasting blood glucose levels and erythrocyte count, and hemoglobin levels in both obese and nonobese patients. The levels of erythrocyte count and hemoglobin of obese patients were higher than those of their nonobese counterparts. This elevation was attributed to the effect of obesity. It is suggested that regulation of body weight should be considered an essential step in the management of diabetes.

Blood Glucose↗
PubMed1987

Pocked erythrocyte counts in patients with hereditary spherocytosis before and after splenectomy.

The pocked (pitted or vacuolated) erythrocyte count has become increasingly utilized as a simple inexpensive test of splenic reticuloendothelial function. Values are less than 2.0% in normal subjects and 20 to 70% following splenectomy. Because scant and conflicting data are available about pocked erythrocyte measurements in hemolytic anemias other than the hemoglobinopathies, we performed pocked erythrocyte counts in 27 patients with hereditary spherocytosis. Prior to splenectomy patients often had elevated values (mean 4.9%). This unexpected observation suggests that hemolytic anemia may result in congestion of the red pulp and/or induced mild splenic reticuloendothelial blockade. As expected, but contrary to a previous report, pocked erythrocyte values following splenectomy were markedly increased (mean 54.9%).

Adolescent↗
PubMed1980

[Investigations of anemia of male rearing calves. 4. Relations between weight at birth, duration of keeping and increase of the ive weight in the period of the calves being fed on colostrum as well as the count erythrocytes in the weaning period of the calves].

With 195 male rearing calves which received concentrates ad libitum beside fluid feed with milk from their 5th day of life onward, investigations were made if and how far the characteristics of the development of the calves while they are fed on colostrum (body weight at birth, live weight increase and duration of keeping or stalling age) correlate with the hemoglobin content (Hb), the hematocrit (Hc) and the average corpuscular hemoglobin concentration (MCHC) of the animals on the 3rd, 28th resp. 56th day of keeping in the weaning period. There was a significant simple dependence particularly between body weight at birth, live weight increase and stalling age on the one hand and the hematologic values on the 3rd day of keeping in the weaning period on the other. A partial correlation analysis showed that the live weight increase while the calves were fed on colostrum was the main variable for all three hematologic parameters at the beginning of the weaning period of the calves. With increasing live weight, Hb, Hc and MCHC were diminished. This analysis was supplemented by the results of a cross--section investigation of the development of the milk and concentrate consumption and the Fe-intake of the calves fed on colostrum. The calculation of the Fe-balance showed that the mere ad libitum supply with feed supplements rich in Fe cannot prevent Fe-deficiency. Anaemia developing in the first month of the calves' lives is not a physiologic one but essentially caused by Fe-deficiency.

Anemia↗
PubMed2005

Relationship between electrophoretic mobility of erythrocytes and blood erythrocyte count in rats.

A significant curvilinear relationship was found between erythrocyte count in rat blood and electrokinetic characteristics of these cells. Electrophoretic mobility of erythrocytes remained unchanged, slightly increased, or decreased with increasing cell count in the vascular bed depending on animal state. Excessive increase in the number of erythrocytes was accompanied by accumulation of cells with low electrophoretic mobility in the electric field.

Animals↗
PubMed1975

Carbonic anhydrase activity and erythrocyte count in the blood of zinc-deficient rats.

Eighteen male Sprague Dawley rats were divided into three groups. They were offered a semisynthetic casein diet containing either 1.2 mg Zn/kg dry matter (depletion group) or 100 mg Zn/kg dry matter (ad libitum and pair-fed control groups). At the beginning and on the 5th and 24th day of the experiment, blood was removed from a tail vein by incision to determine erythrocyte count and carbonic anhydrase activity. The zinc-depleted animals displayed a great increase in erythrocytes during the course of the experiment as compared to the ad libitum control animals. The erythrocyte counts of the pair-fed animals were also increased after 24 days on experiment, but remained significantly lower than those of the depleted animals. The activity of the carbonic anhydrase per ml blood was the same in all groups at the end of the experiment. When, however, the carbonic anhydrase activity was expressed per unit of erythrocytes, the zinc-deficient animals had a significantly lower enzyme activity than both the ad libitum and the pair-fed control rats.

Animals↗
PubMed1975

[Changes in hemoglobin content, erythrocyte count and hematocrit in nickel deficiency].

In a total of four different studies, two of them involving two generations, the essentiality of nickel could be shown by reduced growth in response to a diet with 15 ppb nickel. In 30-day-old self-reared rats, anemia was induced in the Ni-deficient animals despite a high iron supply of 50 mg iron per kg diet. In the F1 generation of the Ni-deficient animals, the erythrocyte count had fallen by 36%, the hematocrit by 37%, and the Hb content by 44%. In the F2 generation in which the animals were given 100 ppm iron, surpassing their requirement three times, the blood parameters of the deficient animals were reduced by 8-10%. At the age of 50 days of the F1 generation the erythrocyte count had fallen 23% compared to the values of the control group, the hematocrit 14%, and the Hb content (16%) from 12.7 to 10.7 g/100 ml blood. An influence on the protein content of the serum and on the catalase activity of the erythrocytes was not observed and only at times was there an influence on the urea content of serum.

Anemia, Hypochromic↗
PubMed1985

Negative correlation between erythrocyte count and mean corpuscular volume or mean corpuscular haemoglobin in diabetic and non-diabetic subjects.

Negative correlation was observed between erythrocyte count (RBC) and mean corpuscular volume (MCV) or mean corpuscular haemoglobin (MCH) in both sexes of diabetic and non-diabetic Libyans. The slopes of regression lines for MCV-RBC and MCH-RBC of diabetic patients were significantly lower (P less than 0.001) than those of their non-diabetic counterparts. Positive correlation was found between MCH and MCV. The slope of the regression line for MCH-MCV of diabetic patients was not significantly different from that of non-diabetic subjects.

Adult↗