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At least 37 records · Page 2Linked to original sources
PubMed1978

[Myocardial energy metabolic disorders in emotional-pain stress and the prevention of these disorders by using sodium gamma-oxybutyrate].

Marked disorders of energy metabolism in the heart muscle simultaneously with the development of ulcerous lesions of the stomach were revealed in animals which had suffered an emotional-pain stress (EPS). These disorders are displayed in the fact that two hours after EPS, the glycogen reserve in the animal's myocardium diminishes, resynthesis of glycogen and oxidation of the main substrates of the tricarboxylic acid cycle are inhibited, and malate dehydrogenase and possibly other dehydrogenase systems of the mitochondria are partly inactivated. Such decrease in the activity of the metabolic tracts is attended by depression of the force and rate of cardiac contractions revealed on inducing a high rate of contractions. The preliminary administration of sodium gammaoxybutyrate to a considerable extent prevents all the changes in the animal's myocardium occurring due to the effect of EPS.

Animals↗
PubMed1979

Perspectives in the treatment of the psychoneurological disorders: affective disorders.

1. Current research strategies in the pharmacotherapy of the affective disorders are reviewed in an attempt to highlight major trends and areas of particular promise. 2. There has been some progress toward the identification of biologically defined subgroups by assessing amine metabolites in urine or cerebrospinal fluid which may lead to a more rational choice of therapies for depressed patients. 3. The use of drugs with receptor agonist properties may help define biological substrates altered in affective illness and lead to new approaches to treatment, such as utilization of low doses of receptor agonists which may preferentially stimulate presynaptic receptors. 4. Study of time-dependent and adaptive changes in receptor sensitivity may also add an important perspective in conceptualizing the cyclic process in manic-depressive illness and its treatment.

Animals↗
PubMed1979

[Situational reactions manifesting themselves in behavior disorders as a form of psychogenic (reactive) disorders in children and adolescents].

The paper is related to the history, elimination, clinical expression, systematics and the clinico-nozological place of the group of situational reactions expressed in disordered behaviour of children and adolescents. These reactions are considered as associated pairs, including interconnected psychological and pathological forms. Some common criteria delineating the psychological and pathological situational reactions are presented. The paper also contains a description of the main traits of psychological and pathological reactions of protest, rejection, imitation, compensation-hypercompensation. All these reactions are considered as a special group of psychogenic (reactive) diseases.

Adolescent↗
PubMed1979

Disordered growth hormone and prolactin secretion in primary disorders of sleep.

Growth hormone (GH) and prolactin (PR) secretion were evaluated in 28 patients who had sleep apnea or narcolepsy but no other primary neurologic or endocrine disorders. Eighty-one percent of subjects with impaired alertness failed to demonstrate serum GH concentrations in excess of 5 ng per milliliter following oral administration of L-DOPA, 500 mg. Diminished GH responses to sleep and intravenous arginine were observed in 57 percent and 44 percent, respectively, of patients tested. Sleep-related PRL release was less than normal in women with narcolepsy, with or without sleep apnea. All patients had at least one abnormality in GH or PRL secretion.

Adult↗
PubMed1978

[Congenital color vision disorders in persons with mental disorders].

Colour vision was studied in 3000 mental patients (2000 males and 1000 females) with different diseases by means of polychromatic tables and a spectral anomaloscope AH-59. It was established that the frequency of genetically determined pathology of colour vision in patients (9,3% in males and 08,% in females) is similar to the pathology found in the general population and does not depend upon the clinical diagnosis. At the same time there was a large amount of patients with acquired disorders to colour perception (30% of the general pathology of colour vision).

Color Vision Defects↗
PubMed1977

The 1977 Bela Schick Memorial Lecture: disorders of suppressor cells in the pathogenesis of immunodeficiency, autoimmune and allergic diseases: human disease associated with disorders of an immunological breaking system.

A series of suppressor cell systems regulate virtually all immunological processes. Disorders of suppressor cells have been identified, including an increased number of activated suppressor T cells in some patients with hypogammaglobulinemia or with selective IgA deficiency. At the other end of the spectrum of immunological response a reduction in suppressor T cell activity has been implicated in the pathogenesis of autoimmune and possibly allergic diseases.

Agammaglobulinemia↗
PubMed1977

[Mental disorders and professional determinants. Study of the time relationship between the beginning of professional life and the first disorder in teachers].

Analysis of the temporal relation between the beginning of mental illness and the beginning of professional life, according to a comparative anamnestic method applied to a group of teachers (N. = 94) and a matching control group of psychiatric paired out-patients (N. = 95). The results show that the distribution of illness prior to professional activity is linked with the diagnostic category and not with professional determinants, psychosis proving to be more impairing than neurosis. A high-risk age group for first incidence of psychotic disease was found.

Adult↗
PubMed1979

[General hemodynamic features in the cerebral circulatory disorders of patients with atherosclerosis and atherosclerosis combined with arterial hypertension accompanied by heart rhythm disorders].

Parameters of the general and cerebral hemodynamics were examined in 45 patients with cerebral circulation disturbances developed in the presence of atherosclerosis (30 patients) and atherosclerosis plus arterial hypertension with cardiac arrhythmias (15 patients) and without the latter (72 patients). The examinations were carried out with the use of the Evans blue dilution method (T-1824) and rheoencephalography. Shifts in the general and the cerebral hemodynamics were revealed in the patients with and without cardiac arrhythmias, these shifts being more pronounced in patients with atherosclerosis complicated with the heart ischemic disease and cardiac arrhythmia. In the course of complex treatment which included cardiotonics and beta-adrenoblocking agents the parameters of the general hemodynamics got better along with the clinical improvement.

Arrhythmias, Cardiac↗