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Neurotoxicities and behavioral changes in a 12-year-old male exposed to dicofol, an organochloride pesticide.

The case of a 12-yr-old male exposed to a substantial amount of dicofol, a DDT analog, is presented. The patient was still contaminated 3 wk after exposure. Blood and fat analysis documented the presence of dicofol. The patient demonstrated subjective and objective evidence of neurological injury, which resolved. Other organ injury was not present. Cognitive and emotional difficulties persisted over an 18-mo period.

Child↗

Dicofol residues in United States soils having a known history of its use as a miticide, 1974.

Soil samples were collected from a total of 21 sites in California, Washington, Florida, Pennsylvania, and Michigan. Dicofol (Kelthane) miticide had been applied at various times over a 5-year period to 17 of the sites; four sites had received no applications. Samples were collected at 0-75-mm and 75-150-mm depths, and submitted to gas-liquid chromatographic analysis. Samples from only four of the 17 treated sites contained mean residues equal to or exceeding 2.00 ppm. Residues in all cases were only a small fraction of the total amount applied. Apparently, a mechanism for the dissipation of dicofol exists, but it is unidentified at this time.

Dicofol↗

Dicofol.

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Animals↗