Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Detroit”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources
PubMed2001

Can communities and academia work together on public health research? Evaluation results from a community-based participatory research partnership in Detroit.

This article reports the results of a formative evaluation of the first 4 years of the Detroit Community-Academic Urban Research Center (URC), a community-based participatory research partnership that was founded in 1995 with core funding from the Centers for Disease Control and Prevention (CDC). Several organizations are members of this partnership, including a university, six community-based organizations, a city health department, a health care system, and CDC. The Detroit URC is a strong partnership that has accomplished many of its goals, including the receipt of over $11 million in funding for 12 community-based participatory research projects during its initial 4 years. Detroit URC Board members identified a number of facilitating factors for their growth and achievements, such as (1) developing a sound infrastructure and set of processes for making decisions and working together, (2) building trust among partners, (3) garnering committed and active leadership from community partners, and (4) receiving support from CDC. Board members also identified a number of ongoing challenges, including organizational constraints, time pressures, and balancing community interests in interventions and academic research needs. Overall, the Detroit URC represents a partnership approach to identifying community health concerns and implementing potential solutions.

Centers for Disease Control and Prevention, U.S.↗
PubMed1984

Physical health of clerical workers in the U.S., Framingham, and Detroit.

The Framingham Heart Study has reported high rates of coronary heart disease among clerical women, compared to other working women and housewives. Using data from the National Health Interview Survey, we find that U.S. clerical women have the best overall profile compared to other occupation groups. They have low injury and chronic limitation rates, little restricted activity, and average health services use. The Framingham clerical women worked mostly before 1960 when clerical work was devalued and the combination of job and family roles put great pressures on women; contemporary clerical women may have more job satisfactions and fewer pressures from multiple roles, and thus lower health risks. In contrast to women, clerical men have a poor health profile compared to other employed men. They have more recent hospitalization and job limitations from chronic conditions. This suggests that men with serious health problems take clerical jobs that are not physically demanding. A health survey of Detroit adults indicates that Detroit clerical men match the national profile, but Detroit clerical women do not. Both groups are dissatisfied with their jobs, compared to other workers. The Detroit data suggests that role pressures and dissatisfactions contribute to poor health, and that people with health problems (especially men) gravitate toward clerical jobs. We need to know more about how perceived role burdens, role dissatisfactions, and weak coping skills influence health.

Adolescent↗
PubMed2006

Seasonality effects on pharmaceuticals and s-triazine herbicides in wastewater effluent and surface water from the Canadian side of the upper Detroit River.

The influence of seasonal changes in water conditions and parameters on several major pharmacologically active compounds (PhACs) and s-triazine herbicides was assessed in the wastewater and sewage treatment plant (WSTP) effluent as well as the downstream surface water from sites on the Canadian side of the upper Detroit River, between the Little River WSTP and near the water intake of a major drinking water treatment facility for the City of Windsor (ON, Canada). The assessed PhACs were of neutral (carbamazepine, cotinine, caffeine, cyclophosphamide, fluoxetine, norfluoxetine, pentoxifylline, and trimethoprim) and acidic (ibuprofen, bezafibrate, clofibric acid, diclofenac, fenoprofen, gemfibrozil, indomethacin, naproxen, and ketoprofen) varieties. The major assessed s-triazine herbicides were atrazine, simazine, propazine, prometon, ametryn, prometryn, and terbutryn. At sampling times from September 2002 to June 2003, 15 PhACs were detected in the WSTP effluent at concentrations ranging from 1.7 to 1244 ng/L. The PhAC concentrations decreased by as much 92 to 100% at the Little River/Detroit River confluence because of the river dilution effect, with further continual decreases at sites downstream from the WSTP. The only quantifiable s-triazine in WSTP effluent, atrazine, ranged from 6.7 to 200 ng/L and was higher in Detroit River surface waters than in WSTP effluent. Only carbamazepine, cotinine, and atrazine were detectable at the low-nanogram and subnanogram levels in surface waters near a drinking water intake site. Unlike the PhACs, atrazine in the Detroit River is not attributable to point sources, and it is heavily influenced by seasonal agricultural usage and runoff. Detroit River surface water concentrations of carbamazepine, cotinine, and atrazine may present a health concern to aquatic wildlife and to humans via the consumption of drinking water.

Canada↗
PubMed2004

Cancer among Arab Americans in the metropolitan Detroit area.

Detroit is home to one of the largest populations of Arab Americans outside of the Middle East, yet little is known about the cancer distribution in this ethnic group. The authors of this study created an Arab/Chaldean surname list and matched it with the Detroit SEER Registry to identify cancer cases of probable Arabic descent. We then determined proportional incidence ratios (PIR) for specific cancer sites among metropolitan Detroit Arab Americans as compared to non-Arab Whites, and contrasted the results with Middle Eastern data. Arab/Chaldean men had greater proportions of leukemia (29%), multiple myeloma (46%), liver (64%), kidney (33%), and urinary bladder (26%) cancers. Arab/Chaldean women had greater proportions of leukemia (23%), thyroid (57%), and brain (35%) cancers as compared with non-Arab White men and women. The cancers with significantly increased PIRs in the Detroit Arab/Chaldean population also are frequently diagnosed in Middle Eastern countries.

Adult↗
PubMed2004

Reducing disparities in diabetes among African-American and Latino residents of Detroit: the essential role of community planning focus groups.

Diabetes is prevalent among African-American and Latino Detroit residents, with profound consequences to individuals, families, and communities. The REACH Detroit Partnership engaged eastside and southwest Detroit families in focus groups organized by community, age, gender, and language, to plan community-based participatory interventions to reduce the prevalence and impact of diabetes and its risk factors. Community residents participated in planning, implementing, and analyzing data from the focus groups and subsequent planning meetings. Major themes included: 1) diabetes is widespread and risk begins in childhood, with severe consequences for African Americans and Latinos; 2) denial and inadequate health care contribute to lack of public awareness about pre-symptomatic diabetes; 3) diabetes risks include heredity, high sugar, fat and alcohol intake, overweight, lack of exercise, and stress; and 4) cultural traditions, lack of motivation, and lack of affordable, accessible stores, restaurants, and recreation facilities and programs, are barriers to adopting preventive lifestyles. Participants identified community assets and made recommendations that resulted in REACH Detroit's multi-level intervention design and programs. They included development of: 1) family-oriented interventions to support lifestyle change at all ages; 2) culturally relevant community and health provider education and materials; 3) social support group activities promoting diabetes self-management, exercise, and healthy eating; and 4) community resource development and advocacy.

Adolescent↗
PubMed1997

Risk of multiple primary cancers in prostate cancer patients in the Detroit metropolitan area: a retrospective cohort study.

BACKGROUND: Patterns of excess risk for second primary cancers (SPC) in prostate cancer patients have been observed for urinary bladder, other sites in the urinary tract, and hematolymphopoietic tissues in several, but not all, previously reported cohort studies. METHODS: The risk of SPC was evaluated in 9,794 Detroit metropolitan-area men originally diagnosed with carcinoma of the prostate during 1973-1982. The cohort was assembled using Detroit Surveillance, Epidemiology, and End Results (SEER) Registry data and followed until December 31, 1993. RESULTS: The observed number of SPC of all sites was similar to the expected number in the cohort. A significant excess of invasive SPC of the urinary bladder [Standardized incidence ratio (SIR) = 1.57; 95% CI, 1.34-1.83] was observed in this cohort, but after excluding the first 2 months after prostate cancer diagnosis, the excess (SIR = 1.06) was no longer statistically significant. The cumulative proportion of patients with prostate cancer who developed bladder cancer during a follow-up interval of 20 years was 5.5% (95% CI, 4.1-6.9%). The patients who received first-course radiation treatment were observed to be at increased risk for bladder SPC (all stages; SIR = 1.49; 95% CI, 1.07-2.02) when compared to the Detroit-area male population. CONCLUSIONS: These results underscore the importance of continuing medical surveillance for urinary bladder second primary cancers in patients with prostate cancer, but are reassuring in that the magnitude of relative and absolute risks does not suggest deterring adverse effects of radiation treatment or intrinsic risks for neoplasms in other organs or tissues.

Adult↗
PubMed2006

PCB levels and trends within the Detroit River-Western Lake Erie basin: a historical perspective of ecosystem monitoring.

An international workshop held in the spring of 2002 convened a group of technical experts to address monitoring, modeling, and management of PCBs within the Detroit River-Western Lake Erie basin. Participants shared and discussed a diverse set of research data bases pertaining to PCB levels within the region, discussed observed changes within different components of the local ecosystem, and identified several primary issues impacting future PCB management strategies. Results presented at the workshop indicate dramatic reductions in PCB contamination levels have been observed in much of study area between the late 1970s and mid-1990s. Estimates of loadings attributable to water and atmospheric sources have generally declined, as have PCB concentrations in herring gull eggs, smelt and walleye. Nevertheless, additional improvements have not been observed during recent years and elevated contamination levels remain a concern within local hot spots, particularly in the lower Detroit River and Trenton Channel. A primary recommendation broadly supported by workshop participants is the need to maintain, support, and coordinate a comprehensive ecosystem monitoring program for the Detroit River-Western Lake Erie basin, one that incorporates both near-field and far-field monitoring elements. Such a program is crucial to provide necessary data in support of understanding ecosystem trends, calculating annual mass loadings to the system, assessing impacts of remediation actions, developing improved modeling frameworks, and formulating cost-effective management strategies for the future.

Animals↗
PubMed2006

Distribution of hexabromocyclododecane in Detroit River suspended sediments.

The distribution of hexabromocyclododecane (HBCD) isomers (alpha, beta and gamma) was determined in Detroit River suspended sediments using liquid chromatography tandem mass spectrometry (LC/MS/MS). Individual isomers of HBCD were measured at concentrations ranging from <0.025 to 1.9 ng/g (dry wt.) for the alpha-isomer, <0.025 to 0.28 ng/g for the beta-isomer, and <0.025 to 2.3 ng/g for the gamma-isomer. Concentrations of total HBCD ranged from <0.075 to 3.7 ng/g. Roughly two-thirds of HBCD profiles in suspended sediments were dominated by the gamma-isomer, and were similar to profiles of commercial technical mixtures. Profiles in the remaining samples were dominated by the alpha-isomer. The beta-isomer was consistently detected at substantially lower levels than the other isomers; this isomer is a minor constituent in the commercial technical mixtures. Seasonal sampling showed significant shifts in the relative ratios of the HBCD isomers. The spatial distribution of HBCD in the Detroit River was similar to other persistent organic pollutants (e.g., PCBs), and showed a strong association with urban/industrial activities in the watershed. However, the highest HBCD concentrations (2.6-3.7 ng/g) were associated with areas of contemporary industrial activity, and were much lower than maximum concentrations of PCBs (2.2 microg/g) found in areas of the Detroit River associated with historical industrial activity.

Environmental Monitoring↗
PubMed2006

Outcomes from out-of-hospital cardiac arrest in Detroit.

OBJECTIVE: To determine the out-of-hospital cardiac arrest survival rate, and prevalence of modifiable factors associated with survival, in Detroit, Michigan, over a 6-month period of time in 2002. METHODS: A retrospective review of all out-of-hospital cardiac arrests responded to by the Detroit Fire Department, Division of Emergency Medical Services. All elements of the EMS runsheet were transcribed to a database for analysis. Patient hospital records were reviewed to determine survival to hospital admission. All survivors to hospital admission were surveyed later in the Michigan Department of Vital Records death registry search. RESULTS: During this study timeframe, there were 538 confirmed out-of-hospital cardiac arrests within the City of Detroit, of which 67 were excluded for being dead on scene [51 (12.5%)] or having no available hospital records [16 (3.0%)]. Of the remaining 471 patients, 443 (94.1%) died before hospital admission. Only 44 (9.9%) of the 471 patients had a first recorded rhythm of ventricular fibrillation (VF), and 339 (76.5%) were asystolic. Of the 28 patients who survived to hospital admission, only 2 (7.1%) were noted to have a first rhythm of VF, and 15 (53.6%) were asystolic. Only one patient survived to hospital discharge. CONCLUSIONS: In this urban setting, out-of-hospital cardiac arrest is an almost uniformly fatal event.

Adolescent↗
PubMed2006

Proximity of schools in Detroit, Michigan to automobile and truck traffic.

Exposure to traffic-related air pollutants, which has been associated with a range of adverse health effects, often is represented using indirect proxies or surrogate exposure measures, most commonly, the proximity to busy roads. This study examines the proximity of grade K-12 schools to high traffic roads in Wayne County, Michigan, an area including the industrialized city of Detroit as well as outlying urban and suburban communities. Unlike earlier studies, commercial and non-commercial traffic is distinguished, and effects of school type (public, charter, private), socio-economic variables, demographic factors, and mapping errors are evaluated. We find that total traffic flow, as measured by annual average daily traffic (AADT), does not reflect the substantial differences between trucking and commuting routes. Thus, AADT alone may inadequately capture traffic-related exposures, especially given the large differences between diesel and gasoline emissions. Based on close proximity (school-road distance < or = 150 m) to heavy traffic (AADT > or = 50,000), 4.9% of the 845 Wayne County schools are traffic exposed at school. In the urban core area, 7.2% of schools and 7.6% of students are traffic exposed at school. A larger proportion of grade 7-12 students in public schools are exposed than K-6 students. Considering truck emissions, 2.8% of the schools are within 150 m of roads with 5000 or more trucks per day. In Wayne County, students attending schools near high traffic roads are more likely to be Black or Hispanic, to be enrolled in a meal program, and to reside in a poor area. Many of these results are driven by the large minority population in the densely populated core area of Detroit. The findings show that a large fraction of children have high exposures to traffic-related pollutants, especially in Detroit, and the need for exposure measures that account for both the composition and volume of traffic.

Adolescent↗
PubMed2007

Yemeni families and child lead screening in Detroit.

This project was an exploratory effort to screen and treat immigrant Yemeni children who were at high risk for lead poisoning. The Detroit metropolitan area is home to the largest number of Arabic immigrants in the United States. In addition, Detroit has the largest rate of childhood lead poisoning in the state of Michigan. No published studies were found that explored the prevalence of lead poisoning among Yemeni children in Michigan. Immigrant children from countries where knowledge of lead poisoning is limited may be particularly vulnerable because of difficulties in language and accessing health care. Children's Hospital of Michigan CATCH School Mobile Health Center conducted this health-screening project. This article reports on the gender and health issues encountered during the community outreach lead testing effort within a Yemeni neighborhood in Detroit.

Arabs↗
PubMed2006

Chronic disease - related behaviors and health among African Americans and Hispanics in the REACH Detroit 2010 communities, Michigan, and the United States.

OBJECTIVES: To compare chronic disease risk factors and their correlates for African American and Hispanic residents of REACH Detroit, Michigan, and the United States. METHOD: Behavioral Risk Factor Survey data from 2001-2003 were used for comparisons and regression models. RESULTS: Several chronic disease risk factors were more prevalent among REACH Detroit residents than their Michigan and U.S. counterparts. In REACH Detroit, greater fruit and vegetable consumption was associated with more than high school education and older age among Hispanics, and meeting exercise guidelines and older age among African Americans. Less than high school education, smoking, and male gender were associated with lower consumption among African Americans. Greater physical activity was associated with younger age, male gender, and more fruit and vegetable consumption among African Americans, and unemployment among Hispanics. CONCLUSIONS: Surveillance of health behaviors in high-risk communities contributes to planning interventions and policies for reducing racial and ethnic disparities.

Adolescent↗
PubMed2005

Racial and Ethnic Approaches to Community Health (REACH) Detroit partnership: improving diabetes-related outcomes among African American and Latino adults.

OBJECTIVES: We sought to determine the effects of a community-based, culturally tailored diabetes lifestyle intervention on risk factors for diabetes complications among African Americans and Latinos with type 2 diabetes. METHODS: One hundred fifty-one African American and Latino adults with diabetes were recruited from 3 health care systems in Detroit, Michigan, to participate in the Racial and Ethnic Approaches to Community Health (REACH) Detroit Partnership diabetes lifestyle intervention. The curriculum, delivered by trained community residents, was aimed at improving dietary, physical activity, and diabetes self-care behaviors. Baseline and postintervention levels of diabetes-specific quality-of-life, diet, physical activity, self-care knowledge and behaviors, and hemoglobin A1C were assessed. RESULTS: There were statistically significant improvements in postintervention dietary knowledge and behaviors and physical activity knowledge. A statistically significant improvement in A1C level was achieved among REACH Detroit program participants (P<.0001) compared with a group of patients with diabetes in the same health care system in which no significant changes were observed (P=.160). CONCLUSIONS: A culturally tailored diabetes lifestyle intervention delivered by trained community residents produced significant improvement in dietary and diabetes self-care related knowledge and behaviors as well as important metabolic improvements.

Adolescent↗
PubMed2000

Non-Hodgkin's lymphoma: an analysis of the Metropolitan Detroit SEER database.

We evaluated incidence and survival trends of non-Hodgkin's lymphoma (NHL) in a large population-based cancer registry. Data regarding demographics, histology, incidence, and survival were obtained on all patients with NHL registered in the Metropolitan Detroit Cancer Surveillance System, a participant in the Surveillance Epidemiology and End Results (SEER) Program of the National Cancer Institute. Incidence and survival trends from 1973 through 1995 were evaluated and stratified based on age at diagnosis, sex, race, and tumor grade. There were 11,978 patients diagnosed with NHL and recorded in the Metropolitan Detroit SEER registry from 1973 to 1995. The age-adjusted incidence rate increased from 8.6 to 15.8 per 100,000, leading to an overall increase in incidence of 83% and an average annual increase of 3.2% per year. Incidence increased significantly (p < 0.05) over time in all age groups except the youngest (ages 0-19) and in all demographic groups studied. Incidence was highest in white men and lowest in black women. The incidence of both low-grade and intermediate/high-grade NHL increased significantly for each age group (p < 0.05) except the youngest (ages 0-19). In the oldest patients (70+ years), the incidence of intermediate/high-grade NHL was almost double that of low-grade NHL. Five-year relative survival increased from 64% (1973-1983) to 68% (1984-1991) for patients with low-grade NHL and from 40% to 44% for those with intermediate/high-grade NHL. The increase in relative survival was only seen in whites, however, with 5-year relative survival in blacks decreased from 53% (1973-1983) to 45% (1984-1991). In metropolitan Detroit, the current NHL epidemic affects all age groups except the very young (ages 0-19), both sexes, and both whites and blacks and is due to increases in the incidence of both low-grade and intermediate/high-grade NHL. Five-year survival rates have increased for whites but not for blacks.

Adolescent↗
PubMed1988

Representation of the black elderly in Detroit metropolitan nursing homes.

This paper presents the results of an analysis of the distribution of black elderly patients in the long-term care systems of Detroit City, Wayne, and Oakland counties, Michigan. These areas were chosen because of their proximity to Wayne State University and because Detroit has a large black population. Wayne and Oakland counties are largely suburban areas. Black, long-term care utilization was compared with the black elderly representation of the base population in these three locations. The sex-specific distribution between whites and blacks in long-term care populations revealed that black men utilized the greatest amount of long-term care and were more dependent on Medicaid. One hundred twenty-one licensed nursing homes were contacted by telephone and a follow-up questionnaire was sent to the respondents during the five-month study périod.It has been observed nationally that the elderly black population is underrepresented in the long-term care system. The findings obtained in this study, however, are not in agreement with the national trend. In Detroit, the black elderly are represented in nursing homes in approximate proportion to their representation in the larger community.This analysis raises questions of need vs utilization of long-term care by the black elderly in urban areas. This is the first study of black elderly long-term care representation in a specific urban area in the United States.

Black or African American↗
PubMed1977

[Karyological study of the continuous cell lines. Comparative analysis of the Hela and Detroit-6 cell lines].

Comparison of the results of the karyologic analysis of two Hela cell sublines (HeLa1 and HeLa2), obtained from different sources, and of Detroit-6 cell line has shown that all the lines contain marker chromosomes characteristic of the HeLa cell line. Detroit-6 cell line marker chromosomes are similar to markers of the HeLa subline (HeLa1). At the same time, part of marker chromosomes in the two sublines of HeLa cell line (HeLa1 and HeLa2) are different. These data show that HeLa1 and Detroit-6 cell lines are more similar than two sublines of the same HeLa cell line.

Bone Marrow Cells↗
PubMed1990

Racial differences in the early detection of breast cancer in metropolitan Detroit, 1978 to 1987.

This population-based study presents trends in stage at diagnosis of invasive female breast cancer during the decade from 1978 to 1987 in the Detroit metropolitan area. Its purpose is to determine whether there has been an increase in early breast cancers: those that are smaller than 2 cm at diagnosis and have no axillary lymph node involvement. Trend analyses of tumor size, node status, year of diagnosis, age, and race were performed for 17,216 incident cases drawn from the Metropolitan Detroit Cancer Surveillance System (MDCSS). Although trends toward earlier diagnosis of breast cancer are observed, less improvement is seen for black women than white women in the presentation of breast cancer at smaller, node-free stages. Implications for breast cancer screening are discussed.

Adult↗
PubMed1994

Descriptive epidemiology of prostate cancer in metropolitan Detroit.

BACKGROUND: The incidence of prostate cancer among US men increased more than five times over the past six decades. Black men in the United States now have the world's highest reported incidence of prostate cancer. The authors examined the distribution of prostate cancer in metropolitan Detroit from 1973 to 1989. METHODS: Cases collected by the Metropolitan Detroit Cancer Surveillance System were used to calculate standardized age-adjusted rates of prostate cancer by race and stage and standardized age-specific rates for the age groups 60-69, 70-79 and 80 years and older. Over 24,000 cases involving black and white men were analyzed. RESULTS: During 1973 to 1989, age-adjusted rates of prostate cancer diagnosed among white men doubled from 54.3 to 109.9 per 100,000 and those among black men increased by nearly 40% from 106.9 to 148.6 per 100,000. Average annual increases in age-adjusted rates for white and black men were 4.4 and 2.3%, respectively. CONCLUSIONS: Age-adjusted rates of prostate cancer diagnosed among white men increased more rapidly than rates among black men during 1973 to 1989. The more rapid increase in cases diagnosed in white men may represent differences in access and exposure to early detection and treatment practices. Improved efforts toward earlier detection are needed, especially among black men.

Age Factors↗