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[Chlamydia trachomatis infection in women with ectopic pregnancy].

Chlamydia trachomatis infection, presumably sexually transmitted, has been implicated in the spread of tubal infertility and ectopic pregnancy. In searching evidence of Chlamydia trachomatis infection as a possible cause of tubal ectopic pregnancy, we enrolled 40 consecutive pathologically proven tubal ectopic women and 37 normal early intrauterine pregnant women from our OPD and ward from Jan. 1989 to July 1989. All cases underwent a structured interview giving particular attention to past reproductive history, contraception history and past history of STD. The levels of serum antibody IgG to Chlamydia trachomatis in all cases were determined. Seven ectopic women with wearing IUD in situ (group A) and 33 ectopic women with no identical factor (group B) were compared with 37 normal early intrauterine pregnant women (control group). The result showed group B more often had IgG antibody to Chlamydia trachomatis than control group (P = 0.001). Group A had higher antibody to Chlamydia trachomatis than control group but the difference was not statistically significant (P greater than 0.05). We concluded that the above findings add to the evidence that Chlamydia trachomatis infection is a major cause of tubal ectopic pregnancy.

Adult↗

[History of contraception and a look to the future].

The desire to limit procreation is as old as mankind. The means to reduce the number of children has been abortion and infanticide rather than contraception. But contraceptive methods have been used already in prehistoric times. They were partly logical, partly illogical and ineffective. Definite improvements were made in 19th century and a more scientific approach began in the 20th century. In order to master the problems of population explosion in developing countries intensive financial and organizational efforts have to be made.

Christianity↗

The adolescent gynecologic exam.

The first gynecologic exam for adolescents can be a positive experience in which they learn about their own body, or it can be a traumatic event. For the practitioner who may not do frequent gynecologic exams it can also be anxiety producing. The exam begins with a complete patient history including menstrual history, sexual history, and contraceptive history. The physical exam includes examination of thyroid, heart, lungs, breasts, abdomen, and genitalia. The nurse's approach can provide the tools the adolescent needs to make it a positive experience.

Adolescent↗

[Risk factors for breast cancer in Belgrade].

Reproductive history, contraceptive use, family history of breast cancer, health behaviour and socioeconomic variables of 60 women with breast cancer were compared to those of 71 age and place of living matched hospital controls. Besides nulliparity, all known risk factors for breast cancer were more frequently present in the cases observed, although the statistical significance was not attained (age at first delivery, early menarche, positive family history of breast cancer, positive history of benign breast disease, obesity). Oral contraceptives ever used were reported for 16.7% of cases and 15.5% of controls (RR = 1.09; 95% confidence interval 0.42-2.77). Although the study is small and the difference in the risk factor distribution insignificant, it is clearly consistent with many published studies on the same subject.

Adult↗

Family history, oral contraceptive usage, and breast cancer.

When breast cancer patients were grouped according to their family history of breast cancer striking differences were found in age distribution. Thus, the proportion of cases less than 45 years of age was grandmother greater than aunt greater than mother greater than FH-negative greater than sister. A similar FH-related sequence was observed in regard to current OC usage among breast cancer patients less than 45 years of age. It also appeared that current oral contraceptive (OC) usage increased the risk of invasive breast cancer among grandmother- or aunt-positive women while decreasing the risk among FH-negative women. There are important practical and conceptual reasons for further studies of the influence of interactions between age, OC usage and family history on the stepwise development of breast cancer.

Adult↗

Characteristics of patients with endometriosis in the United States and the United Kingdom.

OBJECTIVE: To investigate differences in characteristics of patients with endometriosis in the United States and the United Kingdom. DESIGN: Patient questionnaire. SETTING: Two university-based endometriosis referral centers. PATIENT(S): Women with surgically diagnosed endometriosis. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Patient demographics, menstrual and obstetric history, contraceptive use, medical history, risk factors, family history, endometriosis diagnosis, and current pain status and treatment. RESULT(S): Most demographic characteristics were similar between groups. However, patients in the United States were diagnosed at a younger age than were patients in the United Kingdom (25.6 +/- 6.7 years vs. 28.0 +/- 7.1 years) and more commonly presented with an ovarian mass. More U.K. women used oral contraceptives before diagnosis and were younger at first use. U.K. patients underwent fewer additional surgeries than U.S. patients but reported that surgery alone provided the best relief of symptoms, whereas most U.S. patients reported that surgical and medical therapy together provided the best relief of symptoms. CONCLUSION(S): The many similarities in demographics and symptoms among women with endometriosis in the U.S. and the U.K. support the universality of the disease process. Despite a variety of treatments, most patients from both groups still experienced pain from their endometriosis at the time of the survey.

Adult↗