[Seminal colics simulating renal or appendicular colics].
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Appendicitis↗
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[Developmental aspects of Chrohn's disease of colic and ileo-colic localization. Apropos of 17 cases].
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Adolescent↗
[Pyelo-colic fistulas. Apropos of an erroneous radiographic diagnosis of left pyelo-colic fistula].
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Aged↗
Differential calming responses to sucrose taste in crying infants with and without colic.
BACKGROUND: Colic is a behavioral syndrome of early infancy of unknown etiology whose core symptom is increased crying. Both clinical anecdotal descriptions and controlled observations converge in suggesting that a defining characteristic of the crying behavior is the longer duration of the crying bouts, especially during the second month of life when colic is at its peak. This implies that, once infants with colic begin crying, they do not calm as well as infants without colic. To investigate this difference objectively, we used response to sucrose taste as a probe of colic-normal differences in regulation of crying for three reasons. First, sucrose taste has been shown to be a potent regulator of crying in human newborns. Second, convergent evidence from studies in both nonhuman and human infants suggests that sucrose calming reflects the function of central distress regulatory systems that are opioid-dependent. Third, effectiveness of sucrose calming diminishes in normal infants by 4 to 6 weeks of age, consistent with the developmental increase in crying duration common to infants with and without colic. Consequently we predicted that, if the regulation of crying by sucrose taste is relevant to the crying of infants with colic, calming responses to sucrose taste should be less effective in 6-week-old infants with colic compared with those without. OBJECTIVES: To investigate the clinical observation that infants with and without colic differ in their ability to regulate their crying behavior, our primary objective was to determine if there were differential crying responses to intraoral sucrose tastes (relative to water) in crying infants with and without colic. Based on previous studies of calming responses to sucrose taste, it was predicted that sucrose-specific calming before a feeding would be less effective in infants with colic than in those without. A secondary and more exploratory aim was to assess calming responses to sucrose (relative to water) on spontaneous crying after a feed in both groups. METHODS: Nineteen infants meeting modified Wessel's criteria for colic were compared with 19 age- and sex-matched normal infants without colic in a within-subject controlled observation of calming and mouthing responses to both intraoral sucrose and water tastes. Both before and after two feedings on the same day, each infant was observed until she or he cried continuously for 15 consecutive seconds, at which time three 250-microL tastes of 48% sucrose solution or sterile water were administered 30 seconds apart, and infant responses videotaped. Outcome measures derived from second-by-second coding of the videorecordings were percent time crying per minute for 4 minutes and percent time mouthing per minute for 2 minutes after stimulus administration. RESULTS: As predicted, the crying of infants with colic was less affected than the crying of infants without colic after sucrose but not water tastes before feedings. After feedings, the crying of infants with colic was less affected than the crying of infants without colic for both sucrose and water tastes, and sucrose was more effective than water in both groups of infants. These calming differences could not be attributed to differences in mouthing responses because the calming effects persisted after mouthing ceased, and there were no differences in mouthing responses between groups before or after feedings. CONCLUSIONS: As in newborns, a significant calming effect of sucrose taste that persisted beyond the cessation of mouthing could be elicited in crying 6-week-old infants, but it required a stronger taste stimulus to do so. As predicted, infants with colic were less effectively calmed by sucrose taste than infants without. These differential effects could not be accounted for by differences in crying when the stimulus was applied or by differences in mouthing behavior. Before a feed, these differences in calming were specific to sucrose taste. After a feed, infants with c
Colic↗
Prospective study of equine colic incidence and mortality.
A prospective study of one year was conducted on 31 horse farms to obtain population based estimates of incidence, morbidity and mortality rates of equine colic. Farms with greater than 20 horses were enrolled by randomly selecting horse owners from 2 adjacent counties of Virginia and Maryland. Descriptive information for 1427 horses was collected at the initiation of the study and updated at 3 month intervals. Time on the farm during the study was tabulated for each horse. When colic was reported by the owner, investigators visited the farm to obtain information about the colic. The crude incidence density rate of colic was 10.6 colic cases/100 horse-years, based on 104 cases/358,991 horse-days. The median farm specific incidence density rate was 7 cases/100 horse-years, and the range for individual farms varied from 0 to 30 colic cases/100 horse-years. A specific diagnosis was not made for 84 (81%) of colic episodes. Seventy colic episodes (67%) were treated by a veterinarian. Drugs were used in 83 (80%) colic episodes, and 78 (75%) of colic cases were mild, requiring no treatment or resolving after only one treatment. Four horses required colic surgery. Fourteen (13%) horses had more than one episode of colic during the year. Mortality from all causes of death was 2.5 deaths/100 horse-years, mortality rate for colic was 0.7 deaths/100 horse-years. Proportional mortality rate of colic, 28%, was higher than for any other cause of death. Horses less than age 2 years or greater than age 10 years had lower incidence than horses age 2-10 years. No difference in colic risk between genders was identified. Arabian horses had the lowest and Thoroughbreds the highest breed specific incidence rates. Horses used for eventing, or in training had a statistically significant higher incidence rate of colic compared to mature horses with no use (pets, retired, on pasture with no stated purpose). Horses used for lessons or with no use had the lowest incidence rates.
Age Factors↗
Risk factors for colic in the Michigan (USA) equine population.
A population-based prospective epidemiological study was conducted to assess risk factors for equine colic. A stratified sample of 3925 equids in 138 randomly selected equine farms in the state of Michigan was monitored in two 12-month rounds of data collection. Incidence densities were used to describe the rate of development of colic in the study population. Mortality rates, case fatality rates and survival rates were used to describe the severity of colic on the study population. Multivariable logistic regressions with random effects (grouped according to farm) were used to identify risk factors associated with occurrence of colic. A total of 3175 equids from 132 farms from the starting population of 3925 equids in 138 farms was used in the multivariable analysis. There were 77 cases of colic reported during the study period in 62 animals. Of these animals, 54 (87%) had one case, 5 (8%) had two cases, 2 (3%) had three cases, and 1 (2%) had seven cases. Of the cases reported, 49 (64%) were non-specific diagnoses, 13 (17%) impaction/acute intestinal obstruction colics, 7 (9%) spasmodic colics, 4 (5%) sand colics, 2 (3%) gas colics, 1 (1%) verminous mesenteric arteritis, and 1 (1%) enteritis due to ingestion of moldy grain. The annual incidence density of colic in the study was 3.5 cases per 100 equid-years. The surgical treatment risk was 17% (13/77). The overall mortality risk due to colic was 0.5 deaths per 100 equids, and the case fatality risk was 13% (10/77). The case fatality risk for cases treated surgically was 31% (4/13), while the case fatality risk for non-surgical colics was 10% (7/69). Risk factors associated with significantly increased likelihood of developing colic were foaling during the study, deworming during the study, increased age, and participation in showing activities. Geldings and equids provided group drinking water from sources other than tanks, buckets and automatic waterers were significantly associated with reduced risk of colic.
Animals↗
A cross-sectional study of colic in horses on thoroughbred training premises in the British Isles in 1997.
The aim of this study was to estimate the incidence of colic in horses in Thoroughbred training premises in 1997 in the British Isles. The seasonal pattern and outcome of colic episodes were also investigated, together with any association between premises level variables and colic. Data were collected by a postal questionnaire. The results showed a colic incidence density of 7.19/100 horse years (s.e. 0.42) and a cumulative incidence of colic of 5.80% (s.e. 0.30). Premises were grouped according to whether they had more Flat than National Hunt horses (Flat premises) or more National Hunt than Flat horses (NH premises). A similar rate of colic episodes was found in each group. However, significantly higher cumulative incidences of one episode of colic were found in the Flat premises and of multiple episodes in the NH premises, respectively. The outcome of each episode of colic showed spontaneous recovery in 28.7%, medical recovery in 63.1%, surgical recovery in 2.0% and death in 6.2% of cases. This indicated an overall mortality rate from colic of 0.45 deaths/100 horse years. The seasonal pattern of episodes of colic showed a spring and autumn peak, with significant differences in the seasonal pattern between the Flat and NH premises. Relative risk analysis and logistic regression modelling with random effects showed significant associations between the number of episodes of colic and the number of horses on the premises (allowing for the number of horses on each premises, the larger premises had a decreased risk of colic). After adjusting for the number of horses, 3 other variables were associated with colic; Flat premises (with an increased risk), the owner being the sole person looking after the horses (a decreased risk) and the premises being a combined training and breeding establishment (a decreased risk).
Animal Husbandry↗
Dietary and other management factors associated with colic in horses.
OBJECTIVE: To determine whether dietary and other management factors were associated with development of colic in horses. DESIGN: Prospective matched case-control study. POPULATION: 2,060 horses examined by veterinarians in private practice in Texas for colic and noncolic emergencies. PROCEDURE: Each month for 12 months, participating veterinarians were sent forms to collect information on 1 horse with colic and 1 horse that received emergency treatment for a condition other than colic, information collected included signalment, farm management and characteristics, diet, medical and preventive medical factors, transport, and activity or use. Case and control horses were compared by means of conditional logistic regression to identify factors associated with colic. RESULTS: Recent change in diet, recent change in type of hay, history of previous episode of colic, history of abdominal surgery for colic, recent change in weather conditions, recent change in housing, Arabian breed, administration of an anthelmintic during the 7-day period prior to examination, failure to receive regular deworming, age > 10 years, and regular exercise (vs pastured at all times) were associated with increased risk of colic. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that changes in diet (particularly in type of hay fed) contribute to increased risk of colic. A regular program for administration of anthelmintics may reduce the overall frequency at which colic develops, but recent administration of anthelmintics may predispose some horses to colic. Arabian horses may have an increased risk of colic, and horses at pasture may have a decreased risk of colic.
Animal Husbandry↗
Infant colic: empirical evidence of the absence of an association with source of early infant nutrition.
BACKGROUND: The etiology of infant colic remains unknown, despite an abundance of research on the topic. OBJECTIVE: To determine whether breastfeeding has a protective effect in colic's development. DESIGN: A prospective cohort study of 856 mother-infant dyads. Eligible participants included English-speaking adult residents of a region in Ontario, who gave birth, at term, to a live singleton whose birth weight was appropriate for gestational age. Self-administered questionnaires, mailed to mothers at 1 and 6 weeks post partum, requested information on several infant and maternal factors, including source of infant nutrition (exclusively breastfed, complementary fed, and exclusively formula fed). Cases of colic were identified by applying modified Wessel criteria to data recorded in the Barr Baby Day Diary or by interpreting responses to the Ames Cry Score. MAIN OUTCOME MEASURES: Prevalence of colic among breastfed, formula-fed, and complementary-fed infants; and adjusted odds ratios (AORs) reflecting the prevalence of colic among formula- and complementary-fed infants relative to those who were breastfed. RESULTS: Of 856 mothers, 733 (86%) completed the first questionnaire and 617 (72%) completed the second questionnaire. Overall, the prevalence of colic at 6 weeks was 24%. No association was seen between the source of infant nutrition and colic's development. In multivariate analyses, higher levels of maternal trait anxiety (AOR, 1.22; 95% confidence interval [CI], 0.96-1.54), maternal alcohol consumption at 6 weeks (AOR, 1.57; 95% CI, 1.03-2.40), and shift work during pregnancy (AOR, 1.27; 95% CI, 0.73-2.21) were associated with an increased likelihood of colic, after controlling for feeding method, maternal age, and parity. In these same analyses, being married or having a common-law partner (AOR, 0.30; 95% CI, 0.10-0.87) and being employed full-time during pregnancy (AOR, 0.60; 95% CI, 0.32-1.14) were associated with a reduced likelihood of colic. CONCLUSIONS: Breastfeeding did not have a protective effect on the development of colic. Although colic was statistically associated with several variables, including preexisting maternal anxiety, much of colic's etiology remains unexplained.
Adult↗
Family life 1 year after infantile colic.
OBJECTIVE: To determine the persistence of family psychological characteristics associated with infantile colic. DESIGN: A 1-year follow-up survey of families with colicky infants was carried out. The family interview was used to evaluate the psychological factors of colicky and control families. PARTICIPANTS: A total of 59 families with a colicky infant and 58 control families were enrolled in the initial evaluation in the population-based study. On the basis of a structured diary of the infant's crying, filled in by the parents, 3 groups of families were formed: severe colic group (n = 36), moderate colic group (n = 23), and control group (n = 58). The families were interviewed when the infants were 2 and 12 months old. The Beavers-Timberlawn Family Evaluation Scale and the Oulu Family Assessment Scale were used. Thirty-two families (89%) from the severe colic group, 17 (74%) from the moderate colic group, and 49 (84%) from the control group participated in the 1-year assessment. RESULTS: At the 1-year assessment, the structural profile of the families did not differ between the groups. However, families in the severe colic group had more difficulties in communication, more unresolved conflicts, more dissatisfaction, and greater lack of empathy than families in the other groups. Furthermore, there was less flexibility in both colic groups than in the control group. During the follow-up period, coalition between parents in the moderate colic group became stronger compared with the first assessment, and the atmosphere improved significantly in all 3 study groups. However, the amount of empathy decreased in the severe colic group. CONCLUSIONS: Our study shows that certain family characteristics associated with severe infantile colic persist. Families in the moderate colic group coped nearly as well as families in the control group. The family mood had improved a lot in all families when the infant was 1 year old.
Adaptation, Psychological↗
Recurrent colic in the mature horse: a retrospective review of 58 cases.
The clinical features of 58 horses presenting with recurrent colic examined over a 5 year period were reviewed. The horses were categorised into 3 groups on the basis of the history of colic episodes. Recurrent transient colic Group 1 was characterised by 3 or more episodes of transient colic (of apparently similar type) occurring within one month. Recurrent transient colic Group 2 was characterised by 3 or more episodes of transient colic occurring within one year. Recurrent prolonged colic was characterised by 3 or more episodes of prolonged colic occurring within one year. Fifteen horses were classified as recurrent transient colic Group 1. This group had the highest mortality rate 53%. They included 3 horses with lymphosarcoma, 2 with intussusceptions, 2 with thromboembolic disease/verminous arteritis and 2 with partial ileal obstructions. The recurrent transient colic Group 2 comprised 27 cases with a mortality rate of 4%. Nine of these horses were affected by spasmodic colic. The recurrent prolonged group involved 16 horses with a mortality rate of 31%. These included 3 cases of recurrent colonic impaction and 2 cases each of lymphosarcoma, 2 thromboembolic disease, 2 partial ileal obstructions and 2 intestinal adhesions.
Animals↗
Hypercoagulation and hypofibrinolysis in horses with colic and DIC.
Changes in haemostasis in horses with colic were assessed by using specific and sensitive markers of coagulation and fibrinolysis activity. Blood samples from 41 horses with severe colic and from 30 healthy control horses were tested. Diagnosis of DIC was based on the findings of at least 3 of 6 abnormalities: thrombocytopenia, prolonged clotting times (PT and APTT), increased polyclonal FDPs, decreased fibrinogen and decreased AT-III activity. Plasma thrombin-antithrombin III complexes (TAT), monoclonal fibrin degradation products fragment D (D-dimer) and monoclonal fibrinogen degradation products (FgDP) were also tested by using ELISA kits. DIC was diagnosed in 16 of 41 horses with colic. Compared to control and non-DIC colic values, TAT was significantly (P < 0.000) greater in horses with colic and DIC (Control group, mean +/- s.d. 2.6 +/- 2; non-DIC colic group, 7.5 +/- 9, and DIC colic group, 30.9 +/- 36 ng/ml). Also, D-dimer was significantly (P < 0.000) less in the DIC group when compared to control and non-DIC colic values (mean +/- s.d. 677 +/- 119, 682 +/- 220 and 399 +/- 234 ng/ml, respectively). Compared to non-DIC colic values, FgDP was significantly (P < 0.05) lower in the DIC group (363 +/- 111, 437 +/- 230 and 293 +/- 187 ng/ml respectively). Both PT and APTT showed a significant positive correlation with TAT. DIC was more common among nonsurvivors and horses with ischaemic bowel. We conclude that a hypercoagulative state was detected in horses with colic, which was stronger in horses with colic and DIC. Hypofibrinolysis was present only in horses with DIC. Therefore, marked hypercoagulation together with hypofibrinolysis are associated with DIC in horses.
Animals↗
The crying of infants with colic: a controlled empirical description.
To obtain a controlled empirical description of some of the measurable clinical features of colic in a naturalistic context, 38 infants whose mothers considered crying a problem ("colic") and 38 pair-matched control infants were observed and videotaped at home 10 minutes before and after an evening feed. The parents kept a diary of infant behaviors (including crying and fussing) for 7 days following the visit. Following Wessel et al (Pediatrics. 1954;14:421-434), each "colic" infant was classified according to the number of days per week that crying and fussing duration was greater than 3 h/d. The distribution of infants with colic suggested that there were two subgroups: Wessel's colic infants, with 3 days or more per week of more than 3 hours of crying and fussing per day; and non-Wessel's colic infants, with fewer such days. Maternal measures of total daily crying/fussing duration, crying/fussing bout length, and infant temperament and objective analyses of facial activity showed a consistent pattern of differences in which Wessel's colic infants differed from both non-Wessel's colic and control infants, who in turn did not differ from each other. Both colic groups differed from control infants only in the perception of postfeed cries as being more "sick sounding." The results imply that the complaint of colic represents two (or more) groups and that there may be meaningfully distinct colic syndromes. They also provide the first independent empirical support for Wessel and colleagues' clinical distinction between "fussy" and "contented" babies.
Colic↗
Correlations between the colic branches of the mesenteric arteries and the vascular territories of the colon.
The study, done on 100 corpses from the dissection rooms of anatomy laboratory, hinted the morphological variability of the colic arteries and their territories. Morphological variability of the colic branches derived from the mesenteric arteries (superior right colic artery -- 98%; middle right colic artery -- 88%; inferior right colic artery -- 100%; middle colic artery - 36%; superior left colic artery -- 100%; middle left colic artery -- 50%; inferior left colic artery -- 100%) allows us to give out a morphogenetic supposition related their ramification and number. Analyze of the results guide us to a tentative of setting down the vascular territories of the colon. In the beginning were established the territories of the mesenteric arteries (superior and inferior) and after that, were marked the subterritories for each colic artery. Establishing the vascular territories of the colic arteries have not only anatomical importance but also a surgical one, been known the difficult postoperatory colon's revitalization.
Cadaver↗
[Clinical study of colic vessels with respect to their significance in the replacement of the esophagus by the colon].
In 162 cases of esophageal replacement by colon we observed the configuration, distribution and pulsation of the middle, left, right and marginal colic arteries. Observation showed that the middle colic artery had only one major stem in 120 cases, 2-4 branches in 37 cases, and was absent in 5 cases. The middle colic artery originated from the superior mesenteric artery in 126 cases, had one stem originating from the superior mesenteric artery and another from the right colic artery in 10 cases. The middle and the right colic arteries forming one stem and originating from the superior mesenteric artery were seen in 21 cases. The distributive patterns of the middle colic arteries showing "T" type was seen in 37 cases, "V" type in 28 cases, and multiple paralleled branches in 9 cases. Vascular anastomoses between the ascending branch of the left colic artery and the middle colic artery were available in 157 cases (97%), 12 cases with the arc of Riolan. The nearest distance between the marginal artery and the colic wall was at the splenic flexure. The origin of the right colic artery varied greatly and its distributive area was small. We advocated the use of the ascending branch of the left colic artery for blood supply and the transverse colon for replacement of the esophagus in an isoperistaltic fashion (131/162 cases) to be the procedure of choice.
Adolescent↗
Motilin and infantile colic. A prospective study.
Two hundred and nineteen infants, consecutively born, took part in a prospective study of infantile colic from birth to 12 weeks of age. The prevalence of infantile colic in this group was 17.4%. S-motilin was studied in 78 term infants (19 with and 59 without infantile colic) at birth (cord blood), at one day, and at 6 and 12 weeks of age, respectively. Basal motilin levels were raised both in cord blood (p less than 0.01) and in blood from neonates (p less than 0.001) who developed colic as well as in 6 week (p less than 0.05) and in 12-week-old infants with colic (p less than 0.01). Formula-fed infants with colic had higher basal motilin levels than formula-fed controls at 6 and 12 weeks of age (p less than 0.05). Breast-fed infants with colic had higher basal motilin levels than breast-fed controls at 12 weeks of age (p less than 0.05). The raised levels of motilin from the first day of life in infants who develop infantile colic might indicate that the gastrointestinal tract is affected in infants with infantile colic, before any symptoms of colic appear.
Colic↗
Mothers' postpartum psychological adjustment and infantile colic.
BACKGROUND: Infantile colic is a common problem of early infancy. There is limited data on the relation between postpartum maternal psychological problems and colic. AIM: : To investigate whether infantile colic is associated with postpartum mood disorders or insecure adult attachment style of the mother. METHODS: Seventy eight mothers and newborns were enrolled in this prospective, longitudinal study. Maternal depressive symptoms were screened with Edinburgh Postpartum Depression Score (EPDS) and maternal anxiety was assessed with State-Trait Anxiety Inventory (STAI). The Adult Attachment Scale was used to determine the attachment style of the mother. Infantile colic was defined according to Wessel criteria. RESULTS: Infantile colic was present in 17 infants (21.7%); 12.9% of the mothers had an EPDS > or =13. The mean EPDS of the mothers whose infants had infantile colic (10.2+/-6.0) was significantly higher than that of the mothers of infants without colic (6.3+/-4.0). Among infants with infantile colic, 62.5% had mothers who had insecure attachment style, whereas only 31.1% of mothers had insecure attachment when the infant did not have infantile colic. CONCLUSION: Postpartum maternal depressive symptoms and insecure attachment style are associated with infantile colic. Screening and early intervention of postpartum depression might promote the health of both the mother and infant.
Adaptation, Psychological↗
Is equine colic seasonal? Novel application of a model based approach.
BACKGROUND: Colic is an important cause of mortality and morbidity in domesticated horses yet many questions about this condition remain to be answered. One such question is: does season have an effect on the occurrence of colic? Time-series analysis provides a rigorous statistical approach to this question but until now, to our knowledge, it has not been used in this context. Traditional time-series modelling approaches have limited applicability in the case of relatively rare diseases, such as specific types of equine colic. In this paper we present a modelling approach that respects the discrete nature of the count data and, using a regression model with a correlated latent variable and one with a linear trend, we explored the seasonality of specific types of colic occurring at a UK referral hospital between January 1995-December 2004. RESULTS: Six- and twelve-month cyclical patterns were identified for all colics, all medical colics, epiploic foramen entrapment (EFE), equine grass sickness (EGS), surgically treated and large colon displacement/torsion colic groups. A twelve-month cyclical pattern only was seen in the large colon impaction colic group. There was no evidence of any cyclical pattern in the pedunculated lipoma group. These results were consistent irrespective of whether we were using a model including latent correlation or trend. Problems were encountered in attempting to include both trend and latent serial dependence in models simultaneously; this is likely to be a consequence of a lack of power to separate these two effects in the presence of small counts, yet in reality the underlying physical effect is likely to be a combination of both. CONCLUSION: The use of a regression model with either an autocorrelated latent variable or a linear trend has allowed us to establish formally a seasonal component to certain types of colic presented to a UK referral hospital over a 10 year period. These patterns appeared to coincide with either times of managemental change or periods when horses are more likely to be intensively managed. Further studies are required to identify the determinants of the observed seasonality. Importantly, this type of regression model has applications beyond the study of equine colic and it may be useful in the investigation of seasonal patterns in other, relatively rare, conditions in all species.
Animals↗