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PubMed2004

Position of anterior capsulorhexis and posterior capsule opacification.

PURPOSE: To evaluate whether the position of the anterior continuous curvilinear capsulorhexis influences the rate of posterior capsule opacification (PCO). METHODS: A total of 119 patients, aged 61-86 years, underwent cataract surgery with phacoemulsification performed by a single surgeon. The patients were randomized to implantation with either a silicone intraocular lens (IOL) (SI40NB, Allergan) or an AcrySof IOL (MA60BM, Alcon). Three years after surgery, the rate of PCO was analysed using the evaluation of posterior capsule opacification computer software (EPCO). The results were related to the capsulorhexis position, which was assessed with a retroillumination photograph. RESULTS: If the capsulorhexis was located partially or completely off the optics of the IOL, compared to totally on the IOL, significantly more PCO was found (p = 0.0014). When comparing within each IOL type, patients with AcrySof IOLs were found to have significantly less PCO when the capsulorhexis was totally on the optic (p = 0.0048). This difference was also significant in the silicone group (p = 0.041). CONCLUSION: A relatively small and central capsulorhexis allowing for the complete covering of the IOL optics by the rhexis edges seems to protect against PCO in cataract surgery, with both round-edged silicone IOLs and sharp-edged hydrophobic acrylic IOLs.

Acrylates↗

PubMed2006

Efficacy of trypan blue in posterior capsulorhexis with optic capture in pediatric cataracts [ISRCTN48221688].

BACKGROUND: To evaluate the efficacy of trypan blue (0.06%) in posterior capsulorhexis with optic capture in pediatric cataracts. METHODS: In this prospective randomized controlled study, trypan blue dye assisted posterior capsulorhexis with optic capture was performed in 18 eyes (group 1) and no dye was used for posterior capsulorhexis (group 2) in 17 eyes. RESULTS: The mean size of the posterior capsulorhexis was 4.6 +/-1.77 mm and 4.0 +/- 0.93 mm in the group 1 and 2 respectively. Optic capture was possible in 17 eyes in the group 1 and 11 eyes in the group 2. CONCLUSION: Trypan blue facilitates posterior capsulorhexis with optic capture of AcrySof IOL in cases of pediatric cataracts.

Acrylates↗

PubMed2001

Anterior capsular staining with trypan blue for capsulorhexis in mature and hypermature cataracts. A preliminary study.

PURPOSE: To study the efficacy and safety of 0.1% Trypan Blue dye to stain the anterior capsule for capsulorhexis in mature and hypermature cataracts. METHODS: This preliminary study included 25 eyes of 25 patients with a unilateral mature or hypermature cataract, including one case of traumatic mature cataract. In all these cases 0.2 ml of 0.1% trypan blue dye was used to stain the anterior capsule. The efficacy and safety of the dye was evaluated on the basis of intraoperative and postoperative observations. RESULTS: In all 25 eyes the capsulorhexis was completed. There was peripheral extension of the capsulorhexis in the eye with traumatic cataract and the stained edge of the anterior capsule helped identification and redirection of the capsulorhexis. Successful phacoemulsification with intraocular lens implantation was performed in all eyes. Adverse reactions related to the dye such as raised intraocular pressure, anterior chamber inflammation and endothelial damage were not observed in the immediate postoperative period or at the end of mean follow-up of 3 months. CONCLUSION: Trypan blue dye staining of the anterior capsule appears to be a very useful and safe technique that simplifies capsulorhexis in mature and hypermature cataracts.

Adult↗

PubMed1992

Posterior continuous curvilinear capsulorhexis. An experimental study with clinical applications.

The posterior continuous curvilinear capsulorhexis technique has been advocated in cases of posterior capsule rupture during extracapsular cataract extraction. The authors compared posterior continuous curvilinear capsulorhexis with posterior capsular sharp-edged tears. Two different types of forces were experimentally created on the posterior capsule of 30 human eyes obtained after death: (1) implantation and dialing of posterior chamber intraocular lenses (PC IOLs) and (2) increased intravitreal pressure by injection of balanced salt solution. All posterior capsular tears extended toward the equator, causing major capsular defects. In contrast, the posterior continuous curvilinear capsulorhexis remained intact in all cases. This experimental study proves that in cases where an inadvertent posterior capsular tear occurs, a posterior continuous curvilinear capsulorhexis is useful in preventing further capsular damage. Also, in cases where a posterior capsulotomy is indicated, a smooth edge created by a posterior continuous curvilinear capsulorhexis may be useful to maintain the integrity of the capsular bag for PC IOL capsular implantation.

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PubMed1997

Complicated posterior capsulorhexis: aetiology, management, and outcome.

BACKGROUND: A 1 year retrospective analysis of 650 patients, who underwent a posterior capsulorhexis on their intact capsules, was performed to examine the incidence of complications, their aetiologies, and the outcome. METHODS: Data were analysed on 32 patients with complicated capsulorhexis for type of surgery, preoperative and postoperative factors, and relative risk factors for vitreous issue. RESULTS: There were six patients with vitreous loss. The posterior capsulorhexis was uncontrolled in 14 cases and difficult to perform in 12 cases. Implantation into the capsular bag was possible in all cases. Systemic vascular hazard and old age (over 80 years) were found to be statistically significant risk factors for vitreous loss (p = 0.002 and p = 0.03 respectively). The mean follow up was 13.5 months (range 4-25 months). One patient developed a retinal detachment and two had a transient clinical cystoid macular oedema. Visual acuity of > or = 20/40 was obtained in 93% of the patients. CONCLUSION: Loss of control of the posterior capsulorhexis has a low incidence but can lead to serious problems during surgery. A good knowledge of the technique is necessary to complete the procedure with a posterior capsulorhexis of the optimum size without vitreous loss.

Adult↗

PubMed1994

Nucleus viscoexpression compared with other techniques of nucleus removal in extracapsular cataract extraction with capsulorhexis.

We compared three nucleus delivery procedures used during extracapsular cataract extraction (ECCE) after capsulorhexis in 142 eyes. In 25 eyes, the nucleus was expressed through a capsulorhexis 7 mm or wider. In 40 eyes, the nucleus was broken into two pieces and removed through a capsulorhexis 6 mm or less. In 77 eyes, viscoexpression was used to remove the nucleus from the capsular bag through a capsulorhexis 6 mm or less. Nucleus expression after a wide capsulorhexis was successful in 68% of the eyes in which it was attempted. Nucleus fragmentation was successful in 90%. Postoperative inflammation was high in both of these groups. Nucleus viscoexpression was successful in 93%, with low postoperative inflammation. Although it requires a 7- to 8-millimeter corneoscleral incision, based on our study, viscoexpression would appear to be the best nuclear delivery technique when ECCE, rather than phacoemulsification, is being performed.

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PubMed2004

Effect of intraocular lens optic edge design and material on fibrotic capsule opacification and capsulorhexis contraction.

PURPOSE: To examine the influence of intraocular lens (IOL) optic edge design and optic material on fibrosis of the anterior and peripheral posterior capsules and on capsulorhexis contraction. SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: This randomized controlled patient- and examiner-masked study comprised 210 eyes of 105 patients with bilateral age-related cataract. In Group 1 (n = 53), the Sensar OptiEdge AR40e hydrophobic acrylic IOL with a sharp posterior optic edge was compared with the AR40 acrylic IOL with a round edge. In Group 2 (n = 52), the ClariFlex OptiEdge silicone IOL with a sharp posterior optic edge was compared with the PhacoFlex SI-40 silicone IOL with a round edge All IOLs were manufactured by Advanced Medical Optics, Inc. Standardized digital slitlamp images of anterior capsule opacification (ACO) and fibrotic posterior capsule opacification (PCO) were taken 1 year postoperatively, and digital retroillumination images were taken at 1 week and 1 year. The intensity of fibrotic PCO was graded subjectively (score 0 to 4), ACO was graded objectively (score 0% to 100%), and the capsulorhexis area (mm(2)) was determined objectively. RESULTS: One year after surgery, the mean ACO score was 32% in eyes with the sharp-edged acrylic IOL and 29% in eyes with the round-edged acrylic IOL (P<.05). In the silicone group, the mean was 31% and 26%, respectively (P<.05). The mean fibrotic PCO score was lower in eyes with a sharp-edged acrylic IOL than in eyes with a round-edged acrylic IOL (0.26 and 0.93, respectively; P<.05) and in eyes with a sharp-edged silicone IOL than in eyes with a round-edged silicone IOL (0.24 and 0.82, respectively; P<.001). At 1 year, the mean capsulorhexis area was statistically significantly smaller in eyes with a sharp-edged silicone IOL than in eyes with a round-edged silicone IOL (P<.05). CONCLUSIONS: Acrylic and silicone IOLs with the sharp OptiEdge design led to significantly less fibrotic PCO but more ACO than round-edged acrylic and silicone IOLs. The sharp-edged silicone IOL caused significantly more capsulorhexis contraction than the round-edged silicone IOL and both acrylic IOLs.

Acrylic Resins↗

PubMed1999

Complete occlusion of the anterior capsular opening after intact capsulorhexis: clinicopathologic correlation.

PURPOSE: To report histopathologic findings of capsule contraction syndrome with complete occlusion of the capsulorhexis opening. METHODS: Case report. In an 81-year-old woman, a complete occlusion of the anterior capsulorhexis opening developed 2 months after phacoemulsification and intraocular lens implantation. We surgically removed the contracted anterior capsule and analyzed the membrane by standard light microscopy and actin immunohistology. RESULTS: Light microscopic analysis of the membrane showed fibrous tissue subcapsularly with metaplastic lens epithelial cells. The contracted capsulorhexis opening was filled completely with proliferated actin-positive lens epithelial cells. CONCLUSIONS: Complete occlusion of the capsulorhexis opening can be attributed to excessive shrinkage of the capsule, probably caused by actin filaments found in the residual lens epithelial cells together with weak zonular support, and to the occlusion of the remaining central defect by massive proliferation of metaplastic lens epithelial cells.

Actins↗

PubMed2004

[Severe bilateral capsulorhexis contraction after cataract surgery in myotonic dystrophy: a case report].

INTRODUCTION: The Authors report the case of a 50-Year-old man with myotonic dystrophy, who developed severe bilateral capsulorhexis contracture after uneventful cataract surgery. OBSERVATION: Phacoemulsification was performed in both eyes with implantation of intraocular lenses. The patient came to complain of decreased vision in both eyes (4/10 Parinaud 4). Visual acuity initially improved after surgery to 8/10 P2 in each eye. After 7 months for the right eye and 3 Months for the left eye, the patient presented with dramatically reduced vision, caused by a severe capsulorhexis contracture. Anterior capsulotomies with the Nd:YAG laser were performed in both eyes to treat this complication. It was sufficient on the left eye but the right eye required a surgical anterior capsulectomy to remove the IOL and the bag and put in an Artisan lens. DISCUSSION: Capsulorhexis contracture results from fibrous metaplasia of lens epithelial cells from the anterior capsule. Myotonic dystrophy appears to predispose to the development of severe capsulorhexis contracture after phacoemulsification.

Capsulorhexis↗

PubMed1997

Capsulorhexis phymosis following uncomplicated phacoemulsification surgery.

PURPOSE: The aim of the study was to assess and compare the degree of capsulorhexis phymosis following uncomplicated phacoemulsification cataract surgery in polymethylmethacrylate (PMMA) and silicone lens implants. METHOD: Sixty-four patients were evaluated 1 day, 6 weeks and 6 months following phacoemulsification cataract extraction. The anterior capsular diameters were measured with the illuminated beam of the slit lamp at 45 degrees and 135 degrees and the surface area of the opening calculated. We have measured and compared the change in the capsulorhexis size for both lens types and assessed its statistical significance with a paired Student's t-test. RESULTS: A statistically significant contraction of the capsulorhexis was noted in all patients within the first 6 weeks (p < 0.001). Capsular contraction continued between 6 weeks and 6 months post-operatively but to a lesser extent (p < 0.05). The difference in the degree of phymosis between the first period (1 day to 6 weeks) and the second (6 weeks to 6 months) was statistically highly significant for all patients (p < 0.001). The capsular areas for the silicone lens implants were significantly smaller than for the PMMA implants at 6 weeks and 6 months. None of our patients had a clinically significant capsular contracture requiring Nd:YAG laser capsulotomy. CONCLUSION: Anterior capsular contraction is commonly observed following capsulorhexis in phacoemulsification surgery. This study demonstrates that the maximum rate of contraction occurs in the first 6 weeks following surgery and is more pronounced with silicone lens implants.

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PubMed2000

Primary posterior capsulorhexis with optic capture and intracameral heparin in paediatric cataract surgery.

PURPOSE: To study the efficacy of using a primary posterior capsulorhexis with optic capture and intracameral heparin in preventing secondary posterior capsule opacification, in paediatric cataract surgery. METHODS: Primary posterior capsulorhexis and optic capture with a heparin-coated intraocular lens (IOL) was performed after lens aspiration in 14 cataractous eyes of 13 children (group I). Ten international units of heparin were added in the irrigating solution. The results were compared with 14 eyes of 11 children who underwent a similar surgical procedure but without a posterior capsulorhexis (group 2). RESULTS: The mean age of the patients in group I was 4.2+/-1.5 years (mean +/- SD) and in group 2 was 4.5+/-1.8 years (range 3-6 years in both the groups). The mean duration of follow up was 36+/-6.4 months in group I and 38+/-8.1 months in group 2. A best corrected visual acuity of 6/24 or better was achieved in 12 eyes in group I and II eyes in group 2. The visual axis remained clear in all the eyes in group I, while 8 eyes (57.14%) in group 2 developed posterior capsule opacification (P = 0.0034) which required a neodymium:yttrium-aluminum-garnet laser capsulotomy. CONCLUSIONS: Lens aspiration using intracameral heparin, combined with primary posterior capsulorhexis and optic capture of a heparin-coated IOL, is a useful technique to prevent secondary visual axis opacification in paediatric cataracts.

Anterior Chamber↗

PubMed2004

A haptic surgical simulator for the continuous curvilinear capsulorhexis procedure during cataract surgery.

This paper describes a technique for simulating the capsulorhexis procedure during cataract surgery. The continuous curvilinear capsulorhexis technique can be a difficult procedure for beginning ophthalmology surgeons. In the initial phase of tearing the tissue, the tear vector is tangential to the circumference of the tear circle. However, without the proper re-grasping of the flap of torn tissue close to the tear point, the tear vector angle quickly runs downhill possibly causing severe damage to the tissue. Novice surgeons tend to try to complete the capsulorhexis without the time consuming re-grasping of the tissue flap. Other factors such as anterior bowing of the lens diaphragm, patient age, and shallow anterior chambers add to the problematic nature of the procedure. Our capsulorhexis simulator models these various tear problems and anomalies to provide a training environment without the dangers of using live patients.

Capsulorhexis↗

PubMed2005

Simulating the continuous curvilinear capsulorhexis procedure during cataract surgery on the EYESI system.

This paper describes a technique for simulating the capsulorhexis procedure during cataract surgery on the EYESI system. The continuous curvilinear capsulorhexis technique can be a difficult procedure for beginning ophthalmology surgeons. In the initial phase of tearing the tissue, the tear vector is tangential to the circumference of the tear circle. However, without the proper re-grasping of the flap of torn tissue close to the tear point, the tear vector angle quickly runs downhill possibly causing severe damage to the tissue. Novice surgeons tend to try to complete the capsulorhexis without the time consuming re-grasping of the tissue flap. Other factors such as anterior bowing of the lens diaphragm, patient age, and shallow anterior chambers add to the problematic nature of the procedure. The tissue area is modeled as a curvilinear mesh of nodes and springs. Deformation is accomplished via a physically based particle model utilizing a heuristic algorithm to constrain the deformation calculations to the locality of the tear area to speed up computations. The training software alerts the user of any potential tear problems before they occur thus instructing the novice surgeon. The EYESI hardware system (from VRMagic GmbH) provides the user with stereoscopic images thus providing 3D viewing. Our capsulorhexis simulator software models a number of tear problems and anomalies to provide a useful training environment without the dangers of using live patients.

Capsulorhexis↗

PubMed1997

Double contour of the lens capsule edges after continuous curvilinear capsulorhexis.

BACKGROUND: After curvilinear capsulorhexis in cataract surgery often a double-ring shape of the remaining capsular margins can be observed. In order to better understand this phenomenon we performed a histological study of excised capsules after continuous curvilinear capsulorhexis. METHODS: Ten anterior capsular specimens from cases with double-ring structure of the capsular margins after continuous curvilinear capsulorhexis (D-group) were examined light microscopically and compared with 10 normal cases (N-group) and 10 cases with pseudoexfoliation (P-group). Three cases from each group were also examined electron microscopically. RESULTS: A characteristic step formation in the capsular edges and in addition horizontal capsular splits in the border zone between the zonular lamella of the anterior capsule and the capsule proper could be demonstrated histologically in the D-group. CONCLUSIONS: There seems to be a weak point of the capsular tissue in the border zone between zonular lamella of the lens and the capsule proper. The superficial splits that we found histologically in this region might be a precursor or forme fruste of true exfoliation. The outward-directed traction force exerted by the zonular fibers seems to lead to further disruption in this weakened layer of the lens capsule during capsulorhexis, producing a double-ring contour of the capsular margins.

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PubMed1996

Posterior capsulorhexis with optic capture in pediatric cataract and intraocular lens surgery.

BACKGROUND: A major concern in pediatric intraocular lens implantation surgery is the high incidence of posterior capsule opacification. The purpose of this article is to investigate a surgical technique for maintaining a clear visual axis after pediatric cataract and intraocular lens surgery. METHODS: In a prospective evaluation, posterior capsulorhexis with optic capture as a surgical technique for preventing secondary membrane formation after pediatric cataract extraction is investigated. This technique involves capture of an intraocular lens optic through a posterior curvilinear capsulorhexis opening. Perioperative complications and incidence of secondary cataract are presented. Results will be compared to an historic cohort of patients with pediatric cataract-intraocular lens who did not have posterior continuous curvilinear capsulorhexis with optic capture. RESULTS: In 13 consecutive eyes operated on in children aged 2 to 12 years (mean, 5.8 years), there was no opacification of the visual axis at a mean follow-up of 19 months after surgery (range, 8-30 years). CONCLUSION: Posterior capsulorhexis with optic capture holds promise as a technique for preventing secondary membrane formation. This maneuver ensures centration of the posterior chamber intraocular lens while eliminating the need for an anterior vitrectomy. Apposition of the anterior and posterior capsule leaflets anterior to the optic may limit the migration of Elschnig pearls, reducing the incidence of secondary membranes and the need for additional procedures.

Cataract↗

PubMed1997

Radiofrequency diathermy capsulorhexis of the anterior and posterior capsules in pediatric cataract surgery: preliminary results.

PURPOSE: To assess the effectiveness of radiofrequency diathermy capsulorhexis in preventing opacification of the posterior capsule in pediatric cataract extraction. SETTING: The Children's Hospital, Dublin, Ireland. METHODS: Radiofrequency diathermy capsulorhexis to the anterior capsule followed by injection of sodium hyaluronate behind the posterior capsule and primary posterior capsule diathermy capsulorhexis were performed in 14 eyes of 7 children requiring cataract surgery. RESULTS: Six patients had bilateral congenital and 1 patient bilateral developmental cataracts. Ten eyes (5 patients) received heparin-surface-modified intraocular lenses, and 4 eyes (2 patients) were left aphakic. There were no intraoperative complications, and only mild anterior segment inflammation was noted postoperatively. CONCLUSION: With follow-up from 7 to 16 months (mean 12.1 months), our results showed no epithelial regrowth or opacification of the posterior capsule following diathermy capsulorhexis.

Cataract↗

PubMed1993

[Capsulorhexis and manual extracapsular extraction].

Capsulorhexis is the best method of anterior capsulectomy. It is easier to perform a small capsulorhexis, suitable for phacoemulsification than a large capsulorhexis, suitable for a manual extracapsular extraction. We describe manoeuvres enabling the control of tearing the anterior capsule in such a way that the capsulorhexis will be adapted to the passage of the nucleus during the manual extracapsular extraction.

Cataract Extraction↗

PubMed1995

[Continuous circular capsulorhexis in extracapsular cataract extraction].

UNLABELLED: To investigate clinically the advantage, method and prevention of complication continuous circular capsulorhexis, a surgery consisting of continuous circular capsulorhexis, extracapsular cataract extraction and one-piece PMMA intraocular lens (IOL) implantation was performed on 52 eyes. The control was "canopener" capsulotomy made in 40 eyes. The residual anterior capsule and loop fixation of IOL were observed by dilatation of the pupil and gonioscopy 1 month after the operation. RESULTS: Postoperatively an anterior capsular opening of 6.5 approximately 7.0 mm in diameter with sharp edge could be seen in 48 eyes and the fixation of both loops in the capsular bag was found in 44 eyes (84.6%) in capsulorhexis group and 21 eyes (52.5%) in "canopener" capsulotomy group. It is demonstrated that continuous circular capsulorhexis could maintain the integrity of the capsular bag and increase the chance of achieving a fixation of IOL in the bag.

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