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Radiotherapy after definitive surgery for breast cancer.

(1) Radiotherapy after definitive surgery for breast cancer has not been proved to have a deleterious effect on patient survival. (2) The beneficial effect of radiation therapy is to decrease significantly local recurrences (P less than .001), which are very difficult to control once they develop. (3) In the hands of experienced radiotherapists, the incidence of complications is quite low. (4) Adjuvant chemotherapy effects on the prevention of local recurrence are most encouraging but still experimental and should at this stage be used mainly in study situations. (5) Until more detailed information is obtained, radiation therapy remains the most effective, least toxic method for the control of local disease.

Antineoplastic Agents

[Present status of breast cancer surgery in Italy (author's transl)].

Radical mastectomy is the most frequent surgical procedure in breast surgery in Italy. It is indicated in all stages associated or not to complementary therapies. Extended radical mastectomies are performed less frequently than previously. In initial stages of the disease partial mastectomies are performed more frequently. Generally, castration is performed as therapeutic means, not any more for prophylactic reasons. Adrenalectomy and hypophysectomy are seldom associated procedures. As postoperative treatment, Roentgen-Cobalt-Betatrone therapy is still widely used. However, chemotherapy (CMF) is progressively replacing radiation therapy, mostly in the advanced stages.

Biopsy

Combined chemotherapy and surgery in breast cancer: a review.

The current results of trials testing combined surgery and chemotherapy in patients with breast cancer is reviewed. Information concerning eight trials utilizing nine single-agent regimens was obtained. The results at this time are conflicting. There appear to be differences among the regimens utilized in the various patient subsets. Some of the possible reasons for the observed differences, and their implications for future studies, are discussed.

Breast Neoplasms

A critical viewpoint by a general surgeon toward reconstructive surgery after mastectomy.

Reconstructive breast surgery is accompanied by hazards, both known and unknown, which may endanger the life of the patient. On the other hand, the benefits are largely a modest gesture toward the physical and emotional adjustment. It is the duty of the physician to present all aspects of the contemplated procedure and let the patient decide whether her emotional needs justify the risks entailed.

Breast

[Carcinoma of the breast. Reconstructive surgery].

Every year in the German Federal Republic there are 15000 new cases of carcinoma of the breast in woman. In those cases in which metastases in the lymph nodes have not appeared, the rate of recovery is so high that a rehabilitation is worth careful consideration in each case. Methods of operation have been worked out over years of experimentation, with results that are now so good that not only breast-like forms, but genuine female breasts are created. With the reconstruction possibilities, the quality of the patients' survival time is improved.

Breast Neoplasms

[Reconstruction of the breast after surgery for cancer (author's transl)].

The tendency towards less radical, stage-dependent procedures in the surgical management of breast cancer has opened the way to improvement in the reconstructive measures available. Reconstruction of the female breast can be undertaken with greater or lesser success and facility according to whether the initial procedure was subcutaneous mastectomy, modified radical mastectomy or the Rotter--Halstedt radical operation. The different plastic reconstructive methods developed over the past years are discussed and illustrated by cases treated under our care.

Breast