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At least 37 records · Page 2Linked to original sources
PubMed1986

The long-term effect of dietary administration of refined sugars and sugar alcohols on plasma biochemistry, urine biochemistry and tissue histology in mice given a limited degree of dietary self-selection.

A prototype animal feeding model is described in which mice were meal-fed a balanced diet but were given free access to water (controls) or 20% (w/v) solutions of glucose, sucrose, fructose, xylitol or sorbitol. Under these conditions it was found that the provision of an alternative energy source, in the form of a refined carbohydrate, produced marked effects on total energy intake, mouse cube (i.e. balanced energy) intake and body weight. There were also changes in the metabolic states of the animals as assessed by serum levels of glucose, urea and cholesterol, plasma levels of lactate and D-3-hydroxybutyrate, and urinary excretion of urea and oxalate. Histological examinations of tissue indicated that the sucrose-fed mice had a tendency to suffer from acute congestion of the lungs and liver steatosis. Given a limited degree of dietary self-selection it appears that mice are more likely to be at risk of excessive food consumption and obesity when given glucose- or sucrose-containing diets than they are when fructose-, xylitol- or sorbitol-containing diets are given.

Animals↗
PubMed1990

How plants respond to stimuli. The Ninth Annual Symposium on Current Topics in Plant Biochemistry and Physiology sponsored by the University of Missouri Interdisciplinary Program in Plant Biochemistry and Physiology, the US Department of Agriculture, and the National Science Foundation, Columbia, MO, USA, April 4-7, 1990.

With the rapid progress in the identification of the molecular components of calcium and protein kinase regulatory systems, it is presently an exciting time for those studying plant signal transduction. A clear message that was conveyed at the meeting was the need for an interdisciplinary approach to the problems currently facing researchers in this area. Thus, while the powerful methods of plant molecular biology allow for rapid advances in the identification of new molecules, this approach needs to be combined with careful biochemical and physiological analyses. This was exemplified by the large number of protein kinases described at the meeting but the surprisingly few reports of physiological function of phosphorylation. Similarly, while calcium has emerged as a major regulatory molecule in plants, little is known regarding the exact molecular mechanisms of calcium and calcium-modulatory protein action. These are clearly areas for future study that should reveal the elusive pathways that lie between stimuli and responses in the plant cell.

Calcium↗