ARCHITECTURAL BARRIERS TO THE HANDICAPPED.
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[reaction: see text] Base-promoted cyclocondensation of C-chloro oximes with cyclic 1,3-diketones affords functionalized isoxazoles in good yield and under convenient reaction conditions. This process enables the synthesis of highly substituted products with notable functional group tolerance. The products obtained are directly converted to a variety of polyketide-derived polycyclic structures including xanthenes, anthracenes, and benzophenones.
The federal government has passed numerous laws that have focused on everything from civil rights legislation to accessibility mandates. This paper looks at the cumulative effects of federal legislation and nonlegislative activities on breaking down the wall of inequality for persons with disabilities and promoting the concept of universal design and universal access.
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