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Factors associated with iron depletion and iron deficiency anemia among Arabic preschool children of the United Arab Emirates.

OBJECTIVE: The purpose of this study was: 1. To estimate the prevalence of iron depletion and iron deficiency anemia in preschool Arabic children of the United Arab Emirates (UAE), and 2. To determine the risk factors associated with these conditions in this population of children. METHODS: From April through to October 2000 a questionnaire and capillary blood survey was carried out in one primary health care (PHC) centre of Al Ain, UAE. Children whose capillary hemoglobin (Hb) or mean cell volume (MCV) results fell below predetermined cutoffs were offered venous blood workup. An additional sample of children with capillary blood results above those cutoffs were offered the same workup. All blood sampling was completed by May 2001. RESULTS: Five hundred and eight parents were questionnaired and 496 children capillary blood tested. Of the 320 venous blood tested, 315 were analyzed, in relation to questionnaire responses, using univariate analysis and logistic regression. Anemia, iron depletion and iron deficiency anemia were found in an estimated 36.1%, 26%, and 9.9% of this population of children. Age was a significant independent predictor of both iron depletion and iron deficiency anemia. Mother's current pregnancy was an additional predictor of iron deficiency anemia. CONCLUSION: The prevalences of iron depletion and iron deficiency anemia in this population of children were consistent with other reports from the region. Child's age and mother's current pregnancy were predictors of iron deficiency anemia. These findings have important implications for antenatal and childcare both in hospital and primary health care clinics.

Anemia, Iron-Deficiency↗

The impact of emigration on national development in the Arab region: the case of the Yemen Arab Republic.

"The focus of this article is the impact of emigration on national development in labor sending countries experiencing wide-scale emigration, the main contention being that, due to the characteristics of contemporary labor movements among Arab countries, there obtains a contradiction between short term benefits and long term adverse effects. The article briefly defines development, then presents empirical evidence from the Yemen Arab Republic of the negative impact of labor emigration."

Asia↗

Distribution of HLA-DQ alpha and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates.

Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQ alpha and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/ heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.

Blood Proteins↗

The interaction of hemoglobin O Arab with Hb S and beta+ thalassemia among Israeli Arabs.

We have studied 105 individuals in the village of Jasser El Zarka in the Northern Coast of Israel of whom 59% had at least one abnormal hemoglobin. Of the individuals studied 41% were AA, 13.3% AS, 28.6% AOArab, 10.5% SOArab, 0.9% SS, 38% OArab-beta + Thal, and 1.9% beta Thal trait. The SOArab double heterozygotes were characterized by a normal mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC), and an increase of Hb F (11.7 +/- 4.3%) and 2,3-diphosphoglycerate levels (27.8 microns/g Hb). The increase of Hb F is higher than the one seen among OArabs of other ethnic backgrounds. Their clinical course was moderately severe and osteoporosis was quite frequent. The interactions of Hb OArab and Hb S were studied in vitro and it was confirmed the Hb OArab lowers the minimal gelling concentration of mixtures with Hb S (as compared to mixtures of Hb S and Hb A), but that this effect is ionic-strength dependent. Our data are in conflict with previous claims that Hb OArab mixtures with Hb S polymerized almost as much as pure S. Oxygen association curves show a significant displacement of the p50 to the right, but the effect of oxygen dissociation is less apparent. The displacement was not nearly as significant as with SS cells, confirming our gelation data. Blood group determinations establish that these Arab populations had black African admixture. The Hb OArab/beta + Thal double heterozygotes exhibit moderate anemia (10.3 g% of Hb) and the percentage of Hb A was 17.2 +/- 1.8%. The fetal Hb was 5.4 +/- 2.1% and the 2,3-diphosphoglycerate level in two cases was 17.4 mumol/g Hb. The only case of a homozygote SS had moderate anemia (10.3g Hb%), 25.7% of Hb F, and a very benign course.

Adolescent↗