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A review of FaultrEASE version 1.0.

Many systems analysts will be surprised to encounter a program which is billed as a fault-tree development program "perform[ing] logical mathematical operations," but which does not perform Boolean reduction. The rather careful wording quoted in the introduction to this review can, in retrospect, be taken to refer to the fact that gates are quantified using formulas from the calculus of probabilities, and not to claim that Boolean reduction is performed. Since this program does not perform Boolean reduction, its use is limited to essentially graphical applications of the type illustrated in Fig. 1. For this limited application, the program has some features which make it attractive; it is easy to develop and print a passable drawing of a fault tree, and it is easy to do "what-if" analyses (looking at the effects of changing connections or statistics). However, for fault-tree analyses of even moderate complexity, a Boolean processor is necessary (a large fault tree for a real problem in which no events are repeated is arguably a pathological case). Many such algorithms exist on DOS machines, and most of them run within (and are limited to) the usual 640k memory limitation. To be fair, it has to be noted that some commercial algorithms of this type cost far, far more than FaultrEASE (their costs are measured in thousands of dollars rather than hundreds).(ABSTRACT TRUNCATED AT 250 WORDS)

Computer Graphics

An assessment of computing activity by GPASS users in Scottish general practice.

The electronic questionnaire has been developed as a means of collecting data held on computers in Scottish General Practices using the standard national general practice computer system (GPASS). In 1989, data were gathered from 251 computerised Scottish practices using a floppy disc based interrogation program, amalgamated and then analysed. The results of this study are presented and examined in three separate ways: by region, by date of initial computerisation, and by list size per general practitioner (GP).

Computer Systems

A local area network for medical research; planning, realization and experience.

This report focuses on the planning and realization of an interdisciplinary local area network (LAN) for medical research at the University of Heidelberg. After a detailed requirements analysis, several networks were evaluated by means of a test installation, and a cost-performance analysis was carried out. At present, the LAN connects 45 (IBM-compatible) PCs, several heterogeneous mainframes (IBM, DEC and Siemens) and provides access to the public X.25 network and to wide-area networks for research (EARN, BITNET). The network supports application software that is frequently needed in medical research (word processing, statistics, graphics, literature databases and services, etc.). Compliance with existing "official" (e.g., IEEE 802.3) and "de facto" standards (e.g., PostScript) was considered to be extremely important for the selection of both hardware and software. Customized programs were developed to improve access control, user interface and on-line help. Wide acceptance of the LAN was achieved through extensive education and maintenance facilities, e.g., teaching courses, customized manuals and a hotline service. Since requirements of clinical routine differ substantially from medical research needs, two separate networks (with a gateway in between) are proposed as a solution to optimally satisfy the users' demands.

Costs and Cost Analysis

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Acquired Immunodeficiency Syndrome

Human factors. The missing element in computer technology.

Technology is currently more difficult to learn and use than it should be. However, with more attention to human factors, technology will be easier to use in the future. For more information about human factors in computer systems, the reader is referred to two very comprehendible texts: Ben Shneiderman's (1987) Designing the User Interface: Strategies for Effective Human-Computer Interaction or Baecker and Buxton's (1987) Readings in Human-Computer Interaction: A Multidisciplinary Approach. In addition, there is an extensive body of literature on the general subject of human factors.

Computers

A clinical molecular scanner: the Melanie project.

We developed an expert system to analyze and interpret protein maps. This system, Melanie (medical electrophoresis analysis interactive expert), can distinguish between normal and cirrhotic liver and identify various types of cancer on the basis of protein patterns in biopsy specimens. Our findings suggest that some diseases associated with toxic compounds or modifications of the human genome can be diagnosed by expert systems that analyze protein maps. The combination of protein mapping and computer analysis could result in a clinically useful "molecular scanner". The massive amount of information analyzed and stored in such studies requires new strategies, including centralized databases and image transmission over networks. Increased understanding of protein expression and regulation will enhance the importance of the human genome project in medicine and biology.

Computer Systems

Desktop image analysis: workstations of the future.

We report the use of an interactive graphics-oriented workstation to explore quantitative information extracted from medical images. At the University of California at Los Angeles, a Macintosh II personal computer operates as a stand-alone system and images are imported from a central PACS (picture archiving and communication system) server through an Ethernet network. The image-analysis program contains a complete set of general-purpose tools for image manipulation and processing, as well as specific tools for clinical analysis of cardiac and vascular images obtained by various techniques. Most of these features were designed to communicate information through color-coded graphic displays. Ten novice users were given a brief introduction to the program and asked to perform eight analytic tasks. The overall success rate was 95%, and the subjects considered the program easy to use without a manual or formal training. We conclude that with a well-designed graphic interface, physicians without training in the use of computers can easily learn to manipulate and analyze medical images.

Computer Graphics