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At least 343 records · Page 19Linked to original sources

Ultrasonic flowmeters: half-century progress report, 1955-2005.

Ultrasonic flowmeters are one of the fastest-growing technologies within the general field of instruments for process monitoring, measurement and control. Today, acoustic/ultrasonic flowmeters utilize clamp-on and wetted transducers, single and multiple paths, paths on and off the diameter, passive and active principles, contrapropagating transmission, reflection (Doppler), tag correlation, vortex shedding, liquid level sensing of open channel flow or flow in partially-full conduits, and other interactions. Ultrasonic flowmeters are applicable to liquids, gases, and multiphase mixtures, but not without limits. However, no single technology, nor one type of interaction within a technology, can be best for all fluids, occasions and situations. Users who select a particular type of ultrasonic flowmeter over one based on a competing (nonultrasonic) technology often do so for one (or more) of the following reasons: ultrasonic equipment provides a useful measurement whether the fluid is single-phase or not single-phase; equipment is easy to use; flow regime can be laminar, transitional or turbulent; transducers are totally external (no penetration of the pressure boundary); transducers, if not clamp-on, are minimally invasive; no excess pressure drop; when certain conditions are met, accuracy can be better than 0.5%; fast (ms) response; reliable despite temperature extremes; reasonable purchase price, installation, operating and maintenance costs. Sometimes mass flowrate is obtainable. Energy flowrate might be achieved for natural gas and biogas in the near future. How did ultrasonic flowmeters advance in the past fifty years to support such claims? This paper tries to answer this question by looking at ultrasonic flowmeter inventions and publications since 1955, to see how four key problems were solved.

Blood Flow Velocity↗

A finite element model for ultrasonic cutting.

Using a single-blade ultrasonic cutting device, a study of ultrasonic cutting of three very different materials is conducted using specimens of cheese, polyurethane foam and epoxy resin. Initial finite element models are created, based on the assumption that the ultrasonic blade causes a crack to propagate in a controlled mode 1 opening, and these are validated against experimental data from three point bend fracture tests and ultrasonic cutting experiments on the materials. Subsequently, the finite element model is developed to represent ultrasonic cutting of a multi-layered material. Materials are chosen whose properties allow a model to be developed that could represent a multi-layer food product or biological structure, to enable ultrasonic cutting systems to be designed for applications both in the field of food processing and surgical procedures. The model incorporates an estimation of the friction condition between the cutting blade and the material to be cut and allows adjustment of the frequency, cutting amplitude and cutting speed.

Journal Article↗

Ultrasonic speed microscopy for imaging of coronary artery.

We have been developing a scanning acoustic microscope (SAM) system for medicine and biology featuring quantitative measurement of ultrasonic speed and attenuation of soft tissues. In the present study, we will propose a new concept ultrasonic speed microscopy that can measure the thickness and ultrasonic speed using fast Fourier transform of a single pulsed wave instead of continuous waves used in conventional SAM systems. Six coronary arteries were frozen and sectioned approximately 10 microm in thickness. They were mounted on glass slides without cover slips. The scanning time of a frame with 300 x 300 pixels was 121 s and two-dimensional distribution of ultrasonic speed was obtained. The ultrasonic speed was 1720 m/s in the thickened intima with collagen fiber, 1520 m/s in lipid deposition underlying fibrous cap and 1830 m/s in calcified lesion in the intima. These basic measurements will help understanding echogenecity in intravascular ultrasound (IVUS) images. Imaging of coronary artery with the ultrasonic speed microscopy provides important information for study of IVUS coronary imaging.

Algorithms↗

Discussion of parameters associated with the ultrasonic solid-liquid extraction for elemental analysis (total content) by electrothermal atomic absorption spectrometry. An overview.

Ultrasonic solid-liquid extraction (USLE) of trace metals from biological and environmental samples and its subsequent quantification by electrothermal atomic absorption spectrometry (ET-AAS) is nowadays an emerging methodology in the analytical laboratory. However, this methodology is far from maturity as can be readily demonstrated from the controversial data reported by different workers. In the light of our own experience and a survey of published data, a general approach for USLE-ET-AAS is discussed, taking into account the different variables which affect ultrasonic solid-liquid extraction, namely, the ultrasonic device chosen for ultrasonic extraction (e.g. ultrasonic bath or ultrasonic probe), particle size, acid concentration, sonication time and sonication amplitude, sample mass and analyte-matrix binding.

Journal Article↗

Corneal thickness measurements with contact and noncontact specular microscopic and ultrasonic pachymetry.

PURPOSE: To evaluate the central corneal thickness values in normal and postkeratoplasty corneas with the new Topcon SP-2000P noncontact specular microscopic, contact specular microscopic, and the "common standard" ultrasonic pachymetry. METHODS: Central corneal thickness was determined in 119 eyes of 81 patients (73 normal eyes of 44 patients and 46 eyes after penetrating keratoplasty) first with a noncontact specular microscopic (Topcon SP-2000P; Topcon Corporation, Tokyo, Japan), then an ultrasonic (AL-1000; Tomey, Erlangen, Germany), and finally with a contact specular microscopic (EM-1000; Tomey, Erlangen, Germany) pachymetry two times each by the same investigator. RESULTS: Reliability of the central corneal measurements was equally high both in normal and in postkeratoplasty corneas with all of the instruments (Cronbach alpha = 0.99). Noncontact specular microscopic corneal thickness determination correlated significantly both with ultrasonic (r =.86, P <.0001) and contact specular microscopic pachymetry (r =.62, P <.0001). The ultrasonic pachymetry correlated well with the Tomey pachymetry (r =.69, P <.0001). The Topcon normal mean central corneal thickness value (542 +/- 46 microm) was 28 +/- 4 microm lower (P <.0001) compared with the ultrasonic data (570 +/- 42 microm), which was 68 +/- 1 microm lower (P <.0001) compared with Tomey thickness (638 +/- 43 microm). CONCLUSIONS: Central corneal thickness measurements with noncontact specular microscopic, contact specular microscopic, and ultrasonic pachymetry demonstrate that each of the instruments is reliable but cannot be simply used interchangeably.

Aged↗

Dopaminergic modulation of rat pup ultrasonic vocalizations.

The dopamine D(1) receptor agonist, R(+)-6-chloro-7, 8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide (SKF 81297), the dopamine D(2)/D(3) receptor agonist, trans-(-)-4aR-4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H-pyrazolo[3, 4-g]quinoline hydrochloride (quinpirole), and the dopamine D(3) receptor agonist, (+/-)-7-hydroxy-dipropylaminotetralin hydrobromide (7-OH-DPAT) all reduced the frequency of isolation-induced infant rat ultrasonic vocalizations and lowered body temperature when compared to saline-injected controls. Ultrasonic vocalization rate was not affected by either the dopamine D(1) receptor antagonist, R(+)-2,3,4, 5-tetrahydro-8-iodo-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride (SCH 23390) or the dopamine D(2)/D(3) receptor antagonist, S(-)-raclopride-L-tartrate (raclopride) when given alone, nor did these antagonists block the ultrasonic vocalization reductions caused by the dopamine D(1) receptor agonist or the dopamine D(2)/D(3) receptor agonist. The dopamine D(2)/D(3) receptor antagonist but not the dopamine D(1) receptor antagonist blocked the dopamine D(3) receptor agonist's ultrasonic vocalization reduction. SKF 81297 reduced general activity while quinpirole and 7-OH-DPAT increased activity. Raclopride reversed quinpirole's reduction in body temperature, as well as 7-OH-DPAT's effects on body temperature, ultrasonic vocalizations, and activity. These results indicate that dopamine D(1), D(2)/D(3), and D(3) receptor agonists all reduce ultrasonic vocalizations by as yet undetermined mechanisms.

Animals↗

Application of low intensity ultrasonics to cheese manufacturing processes.

Ultrasound has been used to non-destructively assess the quality of many foods such as meat, fish, vegetables and dairy products. This paper addresses the applications of low intensity ultrasonics in the cheese manufacturing processes and highlights the areas where ultrasonics could be successfully implemented in the future. The decrease of ultrasonic attenuation during the renneting process can be used to determine the optimum cut time for cheese making. The ultrasonic velocity increases during maturation for those types of cheese that become harder during this manufacturing stage, thus being an indicator of the maturity degree. Moreover, ultrasonic measurements could be linked to sensory parameters. From the ultrasonic velocity measurements at two different temperatures, it is possible to assess cheese composition, thus allowing an improvement in the quality and uniformity of cheese commercialization. In addition, in pulse-echo mode it is possible to detect cracked pieces due to abnormal fermentations and also to assess the distance of the crack from the surface.

Journal Article↗

Ultrasonic cell disruption of stabilised sludge with subsequent anaerobic digestion.

The world-wide increasing environmental awareness and its subsequent regulations have led to the application of improved technologies in wastewater purification plants. This has resulted in higher wastewater and sludge productions. Sludge is the by-product of such plants and it is not only rich in organic carbon and pathogens but also in heavy metals and other environmental pollutants. In Europe, agricultural application of dried sludge (bio-solids) is confronted with negative reactions from the citizens, governmental organisations, farmers and the food industry. Ultrasonic disruption of sludge is a popular mechanical disruption process in sludge treatment. During ultrasonic treatment, high frequency acoustic signals are used to initiate the cavitation process. The applied ultrasonic field leads to a breakdown of cohesive forces of the liquid molecules resulting in the generation of cavitation bubbles. A shock wave is released by the collapse of the cavitation bubbles and propagates in the surrounding medium forming jet streams that cause the disruption of cells in sludge. Disruption of sludge cells enables the release of light organic substances into the sludge water thereby exposing them for further anaerobic digestion. This paper presents results on the disruption of conventionally stabilised sludge through the application of the ultrasonic field. In order to reduce the specific energy input (i.e. ratio of the consumed energy during ultrasonic disruption to the input sludge mass) and improve biogas production, the total solids content of the stabilised sludge was increased before disruption. The anaerobic digestion of sludge samples was carried out in a set of specially constructed laboratory anaerobic digesters. Results showed that subsequent anaerobic digestion of the ultrasonically disrupted sludge could improve biogas production with reduced sludge quantity that is vital to the economic consideration of the wastewater treatment plants. This process encourages the exploitation of valuable materials and energy from stabilised sewage sludge just before its final disposal. The negative effects of mixing disrupted sludge with its separated sludge water are also shown in this paper. This expresses the microbiological instability of the anaerobic process caused by the mixing process.

Journal Article↗

Thermo-optical modulation of ultrasonic surface waves for NDE.

The well-known thermo-elastic effect of laser irradiation can be exploited to produce strong localized stresses when an expanded, long pulse, low-intensity laser beam is used to irradiate the specimen. These stresses will produce a parametric modulation of the received ultrasonic signals, that is somewhat similar to the acousto-elastic effect often used in nonlinear ultrasonic studies. It is shown in this paper that otherwise hidden small cracks in fatigue-damaged aluminum and titanium specimens can be readily detected by exploiting this optically induced thermo-elastic modulation during ultrasonic surface wave inspection since they are susceptible to crack closure and therefore exhibit strong parametric modulation. The temporal and spatial variations of the ultrasonic signals due to laser irradiation were evaluated numerically and experimentally. Based on these results, the direct temperature modulation of the ultrasonic velocity can be separated from the thermo-elastic stress modulation present only in cracked specimens. It was found that this method can be used to selectively increase the sensitivity of ultrasonic flaw detection to small fatigue cracks by more than one order of magnitude.

Journal Article↗

20 MHz ultrasonic imaging for quantitative assessment and documentation of early and late postradiation skin reactions in breast cancer patients.

BACKGROUND AND PURPOSE: In dermatology high resolution ultrasonic systems proved to be valuable in following up genuine and experimental inflammatory dermatoses. The opportunities of 20 MHz ultrasonic imaging for quantitative assessment of early and late postradiation skin reactions are investigated. MATERIAL AND METHODS: Between April and November 1996, 96 high resolution ultrasound examinations of the skin in 29 patients treated for breast cancer at the University of Ulm were analyzed. Total doses between 46 and 60 Gy were applied. The time interval between the completion of radiotherapy and ultrasonic examination was < or =3 months in 18 patients and 6-135 months in 11 patients. For examinations we used a digital high resolution ultrasonic system with a ceramic 20 MHz transducer. Irradiated and non-irradiated skin were compared. RESULTS: A change of thickness and texture of the dermis depending on the time interval between the completion of radiotherapy and ultrasonic examination and on the administered radiation dose was found. There were significant differences between irradiated and non-irradiated skin regarding the dermal thickness in early (P < 0.001) as well as in late (P = 0.0018) reactions. Echogenicity of the upper and lower corium of irradiated skin decreased in early and late reaction. In upper corium the greatest reduction of signal intensity occurred in early reactions (P = 0.0001). Early reactions of the lower corium differed significantly from late changes (P = 0.001). Discrepancies between visible skin reactions described by examining physicians and ultrasonically proven changes were obvious mainly in late reactions. CONCLUSIONS: There are specific textures of early and late postradiation skin reactions in comparison to non-irradiated skin. High resolution digital 20 MHz ultrasound is non-invasive and quantitative, and in contrast to physical examination, an easy reproducible method for assessing and documenting early and late skin reaction during and after radiation therapy treatment.

Adult↗

Alterations in ultrasonic backscatter during intra-aortic balloon counterpulsation support in patients with acute myocardial infarction.

Alterations of ultrasonic backscatter parameters have been evident in humans with myocardial infarction or ischemia. The backscatter variability could be restored in ischemic or stunned myocardium after reperfusion. The aims of this study were to determinate changes in regional myocardial ultrasonic backscatter during intra-aortic balloon counterpulsation (IABP) support in patients with acute myocardial infarction (AMI), and to evaluate whether backscatter imaging could be a functional guide of IABP support. A total of 9 patients with AMI were investigated during IABP support with a two-dimensional (2-D) ultrasonic backscatter imaging approach for parasternal short-axis view. Coronary angiography was performed in 6 of the 9 patients. A total of 21 vessel territories were studied in different modes of IABP support: 1:1, 1:2 and standby. Restoration of cyclic variation of backscatter after IABP support was demonstrated in 10 vessel territories. Failure of restoration of cyclic variation of backscatter after IABP support was noted in 6 vessel territories with severe coronary lesions (total or nearly total occlusion) or scar tissue. No changes of the ultrasonic backscatter were found in nonischemic vessel territories with patent coronary arteries or TIMI III coronary flow. In addition, the wall motion score did not change significantly with different IABP support. These results suggest that IABP could restore the cyclic variation of backscatter in ischemic myocardium. Myocardial anisotropy may play an influential role in the alterations of ultrasonic backscatter. We propose that ultrasonic backscatter could be a noninvasively functional guide of IABP use in patients with AMI.

Aged↗

Ultrasonication of pyrogenic microorganisms improves the detection of pyrogens in the Mono Mac 6 assay.

The monocytic cell line Mono Mac 6 is sensitive to pyrogens. When exposed to pyrogens secretion of interleukin-6 is induced. However, some eukaryotic pyrogenic microorganisms are not detectable. The aim of this study is to introduce a pretreatment of samples to expand the detection range of the assay. The interleukin-6 inducing capacity of a broad spectrum of UV-killed and ultrasonicated microorganisms is examined in Mono Mac 6 cells. The interleukin-6 secretion is determined in a sandwich immunoassay (DELFIA). The Mono Mac 6 assay is able to detect UV-killed Bacillus subtilis, Staphylococcus aureus and Salmonella typhimurium, but neither Candida albicans nor Aspergillus niger. After ultrasonication of the microorganisms it is possible to detect C. albicans and A. niger. The interleukin-6 inducing ability of the examined microorganisms is in no case reduced after ultrasonic treatment. However, ultrasonication of S. aureus results in a 100-fold increase in the interleukin-6 response. Even after ultrasonication Streptococcus faecalis can not be detected. Ultrasonication is an easy and simple method for expanding the detection range in the Mono Mac 6 assay.

Candida albicans↗

Ultrasonic effects on electroorganic processes--Part 20. Photocatalytic oxidation of aliphatic alcohols in aqueous suspension of TiO2 powder.

Ultrasonic effects in a suspension system were examined using the photocatalytic oxidation of 2-propanol to acetone and of ethanol to acetaldehyde in the aqueous suspension of TiO2 powder as a model reaction. The formation rate of acetone was significantly increased under ultrasonic irradiation. The oxidation reaction under ultrasonic irradiation was affected in a different manner from that in silence by reaction conditions such as ultrasonic power, stirring speed, amount of TiO2, concentration of 2-propanol, and pretreatment of the TiO2 powder. Furthermore, it was also observed that the particle size of the TiO2 photocatalyst powder was increased due to the particle agglomeration by ultrasonic irradiation, and consequently it was suggested that ultrasound activates the surface of the catalyst. These results are discussed on the basis of not only the activation of the photocatalyst but also ultrasonic enhancement of mass transport of 2-propanol molecules.

Journal Article↗

A comparison of the erosive susceptibility of cuspal and cervical enamel using an ultrasonic technique.

The aim of this study was to compare the erosive susceptibility of cuspal and cervical enamel from human premolar and molar teeth. Small blocks of cervical and cuspal enamel were immersed in either orange juice or Coca-Cola at 37 degrees C and the surface enamel loss was measured by surfometry at 1, 2, 3 and 4 h. Additionally, once-hourly enamel loss was measured, specimens were placed in an ultrasonic bath containing water and ultrasonicated for 5 s to determine the degree of surface demineralization. A further set of enamel specimens were prepared that had 100 microm of the enamel surface removed. This was done to remove the hypermineralized surface enamel layer. Surface enamel loss in orange juice at 4 h, following ultrasonication, ranged from 13.2 to 16.9 microm. The surface enamel loss in Coca-Cola at 4 h, following ultrasonication, ranged from 21.7 to 27.5 microm. Subsurface enamel loss in orange juice at 4 h, following ultrasonication, ranged from 10.7 to 16.1 microm. The subsurface enamel loss in Coca-Cola for 4 h, following ultrasonication, ranged from 36.8 to 37.2 microm. Overall, little difference was found in the erosive susceptibility of cervical and cuspal enamel to the effects of orange juice or Coca-Cola.

Bicuspid↗

Age determination of experimental venous thrombi by ultrasonic tissue characterization.

PURPOSE: The ability of ultrasonic tissue characterization based on radiofrequency signal processing to detect compositional differences in thrombi of varying ages was evaluated in vivo. METHODS: Thrombi were produced in 49 jugular veins of 26 anesthetized 18 to 20 kg pigs by partial ligation and application of direct electric current. Thrombi were imaged 30 minutes after formation and 1, 7, and 14 days later with a color Doppler ultrasound scanner that identified the thrombi, and acquired radio frequency data for ultrasonic tissue characterization analysis. Ultrasonic tissue characterization used two parameters from the normalized power spectrum, slope, and intercept, which are related to scatterer size, scatterer concentration, and acoustic-impedance differences between scatterers and surrounding medium. Previous in vitro studies demonstrated that lower slope and higher intercept values correlated with greater cellularity and more-dense fibrin mesh. Histologic examination was performed for each time period. The values of slope and intercept for each timed observation were compared by a multilinear discriminant analysis. RESULTS: There were no statistical differences between day 0 and day 1. Statistically-significant differences in ultrasonic tissue characterization parameters were seen between all other time intervals with p values < 0.01. Older thrombi tended to demonstrate higher slope and lower intercept values. These ultrasonic tissue characterization changes correlated with a red cell and fibrin-mesh density reduction, which was confirmed by histologic findings and was indicative of partial spontaneous thrombolysis. The degree of spontaneous thrombolysis provides an estimate of the age of thrombi. CONCLUSION: Ultrasonic tissue characterization is capable of distinguishing age differences in thrombi in an animal model and has the potential for noninvasive application in clinical diagnosis.

Animals↗

Validity of the ultrasonic technique as a method of measuring subcutaneous adipose tissue.

Subcutaneous adipose tissue measurements, at abdomen, suprailiac, subscapular, and mid-triceps sites, made with the ultrasonic and skinfold caliper techniques were compared using data from 20 women and 17 men from a pool of subjects of 22 women and 20 men. In addition, comparisons were made between ultrasonic, soft-tissue roentgenographic and skinfold caliper techniques at the suprailiac and mid-triceps sites on 6 women and 12 men. Repeat measurements with the ultrasonic technique produced correlation coefficients of 0-87 and above. Correlations between skinfold caliper and ultrasonic measurements were generally higher among women than men over each of the four sites. A highly significant relationship, r = 0-88, was observed between the ultrasonic measurements and soft-tissue roentgenograms over the mid-triceps site. The correlation between the fat-muscle interface measured on the roentgenogram and ultrasonic measurements at the suprailiac site was 0-78. Multiple echoes and interfaces were observed at the suprailiac site on some subjects.

Abdomen↗

Method of evaluating ultrasonic pachometers.

Although many ultrasonic pachometers are commercially available, little has been reported about their performance. We outline a technique for evaluating the accuracy of ultrasonic pachometers by simulating corneal thickness measurements using hydrogel contact lenses. On-eye contact lens thickness is determined using ultrasonic and optical pachometry. Absolute lens thickness is determined using a thickness gauge. Comparisons are made between measurements from the ultrasonic pachometer and measurements from the thickness gauge and optical pachometer. We used this technique to evaluate the performance of the Vida-55 ultrasonic pachometer. This technique was also used to determine the ultrasonic velocity for cat corneal tissue and two hydrogel lens materials. We determined the velocity of ultrasound in cat corneal tissue to be 1590 m/s at 33 degrees C. The velocity of ultrasound in hydroxyethyl methacrylate (HEMA) was 1740 +/- 24 m/s and 1700 +/- 40 m/s in Snoflex 50. We found the Vida-55 pachometer measured corneal thickness accurately when the appropriate ultrasound velocity was used (SEM = 6 microns).

Animals↗

Central corneal thickness measurements using Orbscan II scanning slit topography, noncontact specular microscopy, and ultrasonic pachymetry in eyes with keratoconus.

PURPOSE: To compare corneal thickness measurements using Orbscan II scanning slit topography, Topcon SP-2000P noncontact specular microscopy, and ultrasonic pachymetry in eyes with keratoconus. METHODS: Central corneal thickness was measured in 22 eyes with keratoconus. Eyes with apparent corneal opacity were excluded. Scanning slit topography, noncontact specular microscopy, and ultrasonic pachymetry were used in this sequence. The acoustic equivalent correlation factor (0.92) was used for Orbscan readings. RESULTS: Three devices gave significantly different corneal thickness readings (P < 0.001, repeated-measure analysis of variance). Measurements with Orbscan scanning slit topography (449.5 +/- 43.2 [SD] mum) were significantly smaller than those of ultrasonic pachymetry (485.0 +/- 29.3 microm; P < 0.001, Tukey multiple comparison) and SP-2000P noncontact specular microscopy (476.7 +/- 28.3 microm; P = 0.002). There were significant linear correlations between ultrasonic pachymetry and scanning slit topography (Pearson correlation coefficient r = 0.741, P < 0.001), between scanning slit topography and noncontact specular microscopy (r = 0.880, P < 0.001), and between noncontact specular microscopy and ultrasonic pachymetry (r = 0.811, P < 0.001). CONCLUSION: In eyes with keratoconus, Orbscan II scanning slit topography system gave significantly smaller corneal thickness readings than the other 2 devices. Measurements taken by noncontact specular microscopy and ultrasonic pachymetry were comparable. Three devices showed significant linear correlations with one another.

Adult↗