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At least 343 records · Page 19Linked to original sources

Hypertrophy of inferior turbinates: radiofrequency surgery.

Hypertrophy of the inferior turbinates can be treated by surgical reduction that seems to the most effective approach. Currently, several surgical techniques are performed, like turbinectomy, galvanic or laser cauterization, surgical submucosal decongestion and cryosurgery. In this study, we describe a procedure to reduce the hypertrophy of the inferior turbinates in 60 patients by radio frequency with electrosurgical equipment. The aim of this study is to show how to carry out this technique in the outpatient practice, that allows to face this pathology in an effective and rapid way.

Catheter Ablation↗

[Different treatments of the middle turbinate and maxillary sinus in endoscopic sinus surgery and the curative effect].

OBJECTIVE: To observe the long-term therapeutic efficacy endoscopic sinus surgery with different treatments of the middle turbinate and maxillary sinus. METHODS: Endoscopic sinus surgery was performed in 391 patients with chronic sinusitis and nasal polypi, who were followed up for 0.5 to 2.5 years postoperatively. RESULTS: Of the patients receiving the operation, 328 were cured, 53 showed improvement, and 10 failed to respond to the treatment, with a total efficacy rate of 97.5%. The major complication of this surgery was nasal cavity adhesion. CONCLUSIONS: Appropriate treatment of the middle turbinate and maxillary sinus in endoscopic sinus surgery with postoperative comprehensive therapy may enhance the therapeutic efficacy and reduce postoperative complications.

Adolescent↗

Glycoconjugate expression in normal human inferior turbinate mucosa: a lectin histochemical study.

BACKGROUND: Further study on the composition and concentration of normal nasal mucosal glycoconjugates is needed. METHODS: A battery of ten lectins was used to stain six carbohydrates residing in the inferior turbinate mucosa of 21 healthy individuals. RESULTS: The concentrations of glycoconjugates of the glycocalyx exceeded that of epithelial goblet, ciliated, and basal cells, and also of mucous, serous, and mixed submucosal glands. Epithelial goblet cells and submucosal mucous glands contained relatively high concentrations of glycoconjugates, whereas in epithelial ciliated and basal cells, similar to serous and mixed submucosal glands, concentrations were scanty. The concentrations of N-acetylgalactosamine and galactose were higher in goblet cells than in mucous glands (p = 0.006, and p = 0.056, respectively). Differences in the concentrations of N-acetylglucosamine, fucose, mannose, and sialic acid were insignificant. CONCLUSIONS: The findings provide a baseline for comparison of the composition and concentration of carbohydrates of the normal and pathologic inferior turbinate mucosa.

Glycoconjugates↗

Conchopexy suture to prevent middle turbinate lateralisation and septal haematoma after endoscopic sinus surgery.

Endoscopic ethmoidectomy is now one of the commonest surgical procedures performed by ear, nose and throat surgeons. Access to the ethmoid air cells is via the middle meatus following medialisation of the middle turbinate and uncinectomy. The most satisfactory postoperative results are achieved by maintaining patency of the middle meatus. This allows delivery of topical medication and sinus aeration. Spontaneous lateralisation of the middle turbinate during the healing period, with or without synechiae, can compromise the surgical benefit. This paper describes a conchopexy suture placed at completion of ethmoidectomy. A carefully placed yet simple suture technique will maintain a widely patent middle meatus during the phase of post-operative healing. A slight modification allows quilting of mucoperichondrial flaps after septal surgery.

Cartilage↗

[The usage of inferior turbinate mucoperiosteal flap for repairing cleft palate].

OBJECTIVE: To evaluate a technique for closing the cleft of nasal aspect at the junction of the hard and soft palate and ensuring the wound healing well during the procedures of repairing broad cleft palate. METHODS: A inferior turbinate mucoperiosteal flap based posterior is designed and transposed to the junction of the hard and soft palate for decreasing the tension effectively and closing the cleft easily. RESULTS: All of the patients showed wound healing well and no distinct scars or palatal fistula. CONCLUSIONS: It is a simple and effective technique to decrease the tension and close the cleft of nasal aspect at the junction of the hard and soft palate with inferior turbinate mucoperiosteal flap.

Child, Preschool↗

Inferior turbinate schwannoma: report of a case.

Schwannomas of the nasal cavity are extremely rare. We evaluated a 42-year-old woman who presented with a 4-year history of slowly progressive nasal obstruction. The cause of the obstruction was identified as a schwannoma in the left inferior turbinate. The tumor was completely excised, and no sign of recurrence was evident at the 1-year follow-up. To the best of our knowledge, this is only the third case of a schwannoma originating in the inferior nasal turbinate that has been reported in the English-language literature. We review the clinical and pathologic features of this case.

Adult↗

Nasoendotracheal tube obstruction secondary to inferior turbinate impaction.

This case report discusses one of the unusual complications of nasoendotracheal intubation, amputation of the inferior turbinate with its subsequent impaction of the nasoendotracheal tube. A healthy 19-year-old male underwent surgery for an open reduction and internal fixation of a fractured mandible. Several minutes after nasoendotracheal intubation, airway pressures increased, end-tidal carbon dioxide levels increased, and the patient became difficult to ventilate. The patient was extubated and then reintubated with a smaller-diameter nasoendotracheal tube through the same naris without further sequelae. After examination the tube was found to be occluded with an inferior turbinate. The increased airway pressure and elevated carbon dioxide levels were early signs of partial airway obstruction. Capnography was an important early warning device to provide information prior to changes in other vital signs. It allowed rapid detection of a potentially disastrous obstruction of the airway before the patient experienced severe cardiopulmonary complications. These facts should assist the anesthetist in focusing attention on the possible obstruction of the airway with a foreign body after nasoendotracheal intubation.

Adult↗

Effects of purified Pasteurella multocida dermonecrotoxin on the nasal ventral turbinates of fattening pigs: histological observations.

Fattening specific pathogen-free derived pigs were injected intramuscularly with dermonecrotoxin of Pasteurella multocida, capsular type D. Ten days later, the nasal ventral turbinates and liver were examined histologically. A moderate turbinate atrophy was observed due to an increased number of osteoclasts and the absence of intramembranous bone apposition. Liver lesions were limited to some hepatocyte necrosis, sinusoid neutrophil infiltration and Kupffer cell hypertrophy. This study demonstrated that adult pigs are sensitive to P. multocida dermonecrotoxin.

Animals↗

Virus-induced lysosomal enzyme dissolution of nasal turbinate cartilage.

The mechanism of laryngotracheitis virus-induced dissolution of chick nasal turbinate cartilage was studied by lysosomal enzyme histochemistry. Five-day-old chicks were infected by intranasal instillation, and changes in lysosomal enzyme distribution were followed at daily intervals through the tissue regeneration stage, Day 28. In the mucosa the lysosomes were activated beginning on Day 1, and glycerol acid phosphatase and a diffuse form of beta-glucuronidase were released concomitant with tissue cell destruction. In the chondrocytes (where glycerol acid phosphatase was absent), beginning on Day 2, particulate (lysosomal) beta-glucuronidase decreased as diffuse beta-glucuronidase increased and extended out into the matrix. The cartilage lost its metachromatic staining properties and became soft and pliable. Regeneration of the mucosa started on Day 6 and gradual reappearance of metachromatic staining of the cartilage began on Day 8 with considerable recovery of original turbinate structure by Day 12. A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.

Acid Phosphatase↗

Acute dacryocystic retention cured by inferior turbinate infracturing.

A 30-year-old man with recurrent acute dacryocystic retention had successful infracturing of the inferior turbinate bone in association with probing of the lacrimal outflow system. Enlargement of the inferior nasal meatus by fracturing the turbinate is easy to do and would be indicated before recommending a dacryocystorhinostomy in cases of acute dacryocystic retention in which the causative cast is difficult to eliminate even by large probes that can be passed down the nasolacrimal duct.

Acute Disease↗

Host response to Pasteurella multocida turbinate atrophy toxin in swine.

A porcine strain of Pasteurella multocida (serotype D:3) produced a toxin causing turbinate atrophy (TA) in pigs. The toxin (TAT), processed on a high performance liquid chromatography size exclusion column, eluted as a single peak (molecular weight of about 160,000) containing trace amounts of endotoxin (lipopolysaccharide, LPS; protein:LPS, 85:1). The eluted fraction migrated on sodium dodecyl sulfate polyacrylamide gels as a single band. It could be prevented from dissociating into two prominent polypeptides by addition of a protease inhibitor. A single dose (2.0 to 79.0 micrograms/kg) of TAT given to pigs intravenously was lethal. Doses from 0.02 to 1.0 microgram/kg caused transient clinical signs of porcine systemic toxicosis with reduced appetite, generalized weakness, depression, lethargy, weight loss, and in some instances, death. Intradermal doses of TAT (greater than or equal to 0.1 microgram/site) produced hemorrhagic areas within four hours. Systemically, TAT causes bilateral TA, lymphopenia, liver dysfunctions, and possible renal impairment. Affinity of TAT for cells of epithelial origin was demonstrated in mice given 125I-TAT. In vitro, TAT stimulated DNA and protein syntheses of peripheral blood lymphocytes and suppressed syntheses in turbinate and kidney cell cultures without being cytolytic. Biological effects of TAT were eliminated by exposure to either heat, trypsin or anti-TAT antibody.

Animals↗

[Submucous resection of the lower bony turbinate].

The technique, results, and complications of 43 patients operated upon, by submucous turbinal resection (STR), is presented (1985-1988). To cope with bony turbinal problems, either "in totto", or submucose resections are a "must". The author claims STR is more functional than the other possible techniques. Properly done, good results are to be expected, through minimal, transient risk, of tracheo-pharyngeal dryness.

Humans↗

[Infraction of the middle turbinate in the treatment of sinusitis. A general practice report].

The results of infracture of the middle turbinate in 98 patients with chronic sinusitis are reported, particularly with respect to the effects on headache, nasal obstruction and catarrh (post-nasal discharge). The case records were taken in alphabetical order from the outpatient department of a private clinic for the years 1962-1974. The results were generally very satisfactory for headache and nasal obstruction (90% and 65% positive respectively). Its influence on catarrh was much less impressive (36%). Infracture of the middle turbinate is a simple and highly effective procedure which can be carried out before or at the same time as intranasal surgery, as it does not exclude later operations, but often makes them unnecessary.

Adolescent↗

Development of turbinate lesions and nasal colonization by Bordetella bronchiseptica and Pasteurella multocida during long-term exposure of healthy pigs to pigs affected by atrophic rhinitis.

Natural transmission of atrophic rhinitis from pigs from a herd with an endemic atrophic rhinitis problem to pigs from a herd free of atrophic rhinitis was demonstrated. Six replicates each with five pigs from the endemic atrophic rhinitis herd (Group A) and five pigs from the atrophic rhinitis-free herd (Group B) were housed together from 5 wk of age, with each replicate kept in isolation rooms maintained at optimal and controlled environmental conditions. Three replicates each with six pigs/room from the atrophic rhinitis-free herd (Group C), served as nonexposed controls. Group C pigs remained healthy and had no turbinate atrophy at either 10 or 17 wk of study (atrophic rhinitis score = 0 on a 0 to 3 scale). Group A pigs had a mean atrophic rhinitis score of 1.85 +/- 0.84, and group B pigs developed atrophic rhinitis to a mean score of 1.57 +/- 0.70. The isolation rate and quantity of Pasteurella multocida found on nasal swabs was directly related to lesions while those for Bordetella bronchiseptica were inversely related to turbinate atrophy. Of the various types of P. multocida evaluated, nontoxigenic type A and toxigenic type D were both directly related to atrophic rhinitis while nontoxigenic type D strains were not. No toxigenic type A P. multocida strains were isolated.

Animals↗

[Histologic changes in the epithelium of the respiratory mucosa of the lower turbinates following argon laser strip carbonization in vasomotor rhinitis].

The histological findings after argon-ion-laser-carbonization on the respiratory mucosa of the lower turbinates in vasomotor rhinitis are described directly after laser treatment and 6 years later. The laser surgical procedure without bleeding, the reduction of swelling of the lower turbinates, a slight diminishing of secretion, a significantly better nasal ventilation are demonstrated by the histological findings. The main characteristic histological findings are: a cuneiform laser lesion extending deep into the tissue to the venous plexus, four different typical tissue layers immediately after laser treatment, centrally the carbonization zone surrounded by a coagulation zone and next to this a honeycombed zone surrounded by a very small oedematous zone. Healing of the laser lesion is always complete. First of all, a squamous epithelium with subepithelial fibrosis and hypertrophy of the muscle cells in the venous plexus are seen. Half a year after laser carbonization metaplasia of the stratified squamous epithelium into pseudostratified cylindrical ciliated epithelium is seen. Occasionally, small islands of stratified squamous epithelium are visible.

Adolescent↗

[Submucous turbinate resection].

This article describes the authors' experiences on submucous resection of the turbinate bone in chronic hypertrophic lower turbinates. Similar to the procedure in septoplasties, this surgery preserves the mucosa and its physiological properties. The technique is facilitated by an amazingly low tendency to bleeding. 70 patients were followed up post-operatively. More than 70% reported a marked improvement of nasal breathing. No serious complications were seen.

Adolescent↗

Density of goblet cells on normal adult nasal turbinates.

On the basis of 10 middle and 10 inferior turbinates from autopsies on normal adults, a quantitative study of the goblet cells was performed, using the whole-mount method. There was quite some increase in density into the posterior direction, with a generally higher density on the inferior than on the middle turbinate. The results are related to the current of air in the nose.

Age Factors↗

Ultrastructural changes in the nasal turbinate bones of pigs in early infection with Bordetella bronchiseptica.

The ultrastructural changes in the turbinates of young pigs killed four, seven, 14 and 28 days after intranasal inoculation (dpi) with Bordetella bronchiseptica were restricted to osteoblasts. In a few cells irregularities and evagination of the nuclear membrane were associated with enlargement of the Golgi apparatus at four dpi. By seven dpi many osteoblasts had these changes and also a dilatation of the endoplasmic reticulum while mitochondria retained normal definition: an amorphous degeneration occurred within the enlarged Golgi apparatus. These features had progressed at 14 and 28 dpi to produce shrunken osteoblasts with small, irregular nuclei, a grossly distended endoplasmic reticulum, absent or degenerate Golgi apparatus, but apparently intact mitochondria. At this stage the numbers of osteoid fibres were greatly reduced and macroscopic hypoplasia of the turbinates was observed.

Animals↗