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Results for “RETINAL VESSELS”

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At least 343 records · Page 19Linked to original sources
PubMed1993

Three-dimensional structure of human retinal vessels studied by vascular casting.

A new casting technique for studying the three-dimensional structure of the human retinal vascular system on post mortem tissue was developed. The technique was designed to provide an overview presentation of the retinal vasculature such that localized areas with vascular pathology could be identified for further analysis of three-dimensional structure. The paper presents qualitative characteristics of three-dimensional structure in the normal human retinal vascular bed, to provide a basis for future studies on vascular impairment in retinal disease.

Capillaries↗
PubMed1990

The response of the light reflex of retinal vessels to reduced blood pressure in hypertensive patients.

The response of retinal arteries and veins to 3 months of antihypertensive medication was studied in 10 patients (39-56 years old) with essential hypertension. We used computerized microdensitometry on fundus photographs, a technique allowing for objective and simultaneous measures of the caliber of blood columns and the width and intensity of their central 'light reflex'. A moderate lowering of diastolic and systolic blood pressures (P less than 0.001) resulted in a significant reduction in the intensity of reflection from retinal arteries (38.6%; P less than 0.005). An increase in the width of the blood column (2.8%; n.s.) and the reflex (8.6%; n.s.) was indicated. Traditionally, changes in light reflectivity has been associated with arteriosclerosis of the vessel wall. The study shows, however, that the vascular reflex is most sensitive to changes in the systemic blood pressure. This signals a need for critical reviewal of interpretation and usefulness of classical grading systems of ophthalmoscopic signs of hypertensive retinopathy.

Adult↗
PubMed2000

Light and electron microscopic examination of endothelial cells from bovine retinal vessels in long-term cultures.

The aim of the present work was to examine and compare the ultrastructure of bovine retinal endothelial cells (BRECs) in vitro during several passages in a medium selective for endothelial cells. The identity of the endothelial cells was confirmed immunohistochemically, up to the tenth passage. Changes in their ultrastructure in comparison to endothelial cells in vivo occurred at the onset of culturing and not progressively with repeated passages. The cultured BRECs show high metabolic activity in all passages. While retaining their identity as endothelial cells, they modify their lipid metabolism, so that lipids are stored. This change in lipid metabolism was induced by the medium.

Animals↗