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PubMed1981

Hypoplasia of the latissimus dorsi muscle complicating breast reconstruction in Poland's syndrome.

Poland's syndrome includes anomalies of the breast, thorax, and upper extremity. Unilateral hypoplasia of the breast and pectoral muscle are seen most frequently, and the resulting problem of breast reconstruction must be addressed. The latissimus dorsi myocutaneous flap is one of the most useful reconstructive tools in this situation. A case is presented of Poland's syndrome with hypoplasia of the latissimus dorsi muscle-an abnormality not generally associated with Poland's syndrome. The latissimus dorsi muscle should be carefully evaluated preoperatively in such patients, to make sure it is adequate for reconstructing the absent breast and pectoral muscle.

Adult↗
PubMed1997

Two clones of methicillin-resistant Staphylococcus aureus in Poland.

OBJECTIVE: To evaluate relatedness among methicillin-resistant Staphylococcus aureus (MRSA) strains isolated in Poland. METHODS: Ninety-three MRSA hospital isolates were collected from different regions in Poland from 1990 to 1992. Strains were analyzed with respect to heterogeneity of methicillin resistance, phage types, resistance patterns, crystal violet staining, chromosomal DNA SmaI restriction patterns by PFGE, ERIC1 and ERIC2 AP-PCR types and DNA repeat polymorphism within the protein A gene. Resistance to methicillin was confirmed by the detection of the mecA gene by PCR. RESULTS: The combined results of typing methods demonstrate that all MRSA strains analyzed could be easily divided into two distinct clones (clonally related strains). The first consisted of strains with clear heterogeneous expression of resistance to methicillin (34 isolates) and the second showed more homogeneous resistance (59 isolates). In this study the best method for epidemiologic analysis of MRSA was found to be PFGE. A good correlation between the epidemic behavior of MRSA and a high number of repetitive DNA units within the protein A gene was observed. CONCLUSIONS: Results show that in Poland two distinct clones of epidemic MRSA have circulated in the past, easily discriminated by pheno- and genotyping methods, and both could be found together in a single hospital.

Journal Article↗
PubMed1982

Debendox does not cause the Poland anomaly.

The suggestion that Debendox may cause the Poland anomaly is refuted by a study of the antenatal drug exposure in 46 cases of the Poland anomaly and 32 cases of isolated absence of the pectoralis major. Debendox had been prescribed in one case of the Poland anomaly and in one case of isolated pectoralis absence, but in neither was the compound given during organogenesis. In none of the 78 cases could Debendox be causally implicated.

Abnormalities, Drug-Induced↗
PubMed1981

Poland-Möbius syndrome.

A patient with stigmata of both the Möbius syndrome and the Poland syndrome is presented. This is now the twelfth well-documented patient with a combination of the two syndromes. The association of the Poland syndrome and the Möbius syndrome occurs with sufficient frequency that the combination probably represents a formal genesis malformation syndrome of unknown aetiology that should be designated the Poland-Möbius syndrome.

Abnormalities, Multiple↗
PubMed1982

Familial Poland anomaly.

The Poland anomaly is usually a non-genetic malformation syndrome. This paper reports two second cousins who both had a typical left sided Poland anomaly, and this constitutes the first recorded case of this condition affecting more than one member of a family. Despite this, for the purposes of genetic counselling, the Poland anomaly can be regarded as a sporadic condition with an extremely low recurrence risk.

Adult↗
PubMedDate not supplied

[Self-reported health and life satisfaction in school-aged children in Poland and other countries in 2002].

AIM: to present results of the study concerning: self-reported health, frequency of subjective complaints and life satisfaction among adolescents in Poland and 31 other countries. MATERIAL AND METHODS: the survey was carried out in 2001/02, on representative for each country samples of pupils aged 11, 13, 15 years in the frame of HBSC survey (Health Behaviour in School-aged Children: A WHO Collaborative Cross-national Study). The total sample size was 162306, in Poland it was 6383. The international standard questionnaire was used. RESULTS: the majority of adolescents considered themselves as healthy or very healthy and satisfied with their life. These percentages were lower for girls and decreased with age. Every third pupil experienced two or more subjective complaints more than once a week or daily. The highest percentages of adolescents rating their health as fair or poor and unsatisfied with their life were in countries of the former Soviet Union. Multiple health complaints were experienced most often by adolescents in the Mediterranean countries (Greece, Italy, Israel, Spain). In Poland, in comparison with other countries in the survey, adolescents more often rated their health as very good, but many pupils experienced subjective complaints and felt unsatisfied with their life.

Adolescent↗
PubMed1976

[Moebius' syndrome and Poland's anomaly (author's transl)].

The syndrome of Moebius and Poland's anomaly have some features in common. The malformations of the limbs-especially those of the fingers (brady-, syn-, symbrachydactyly)-are identical in both disorders. Hypoplasia of the m. pectoralis major, characteristic for Poland's anomaly, may accompany Moebius' syndrome and cerebral nerve pareses may be associated with Poland's anomaly, thus distinction between the two disorders may be impossible. Both disorders affect the embryo at the same gestational age and the causative factor is unknown in either of them. Simultaneous evaluation of findings observed in patients suffering of either condition should be performed to elucidate pathogenesis and aetiology.

Abducens Nerve↗
PubMed1965

PRESENT STATUS OF MEDICAL EDUCATION IN POLAND.

In the past few years medical education in Poland has undergone considerable change, particularly at the graduate and postgraduate levels, and has shown increasing Western influences. On the negative side, a physician who was trained in pre-war Poland and is now in the United States, noted mass production of physicians with modest clinical facilities and the preponderance of didactic lecturing over semi-individual instruction-conditions rather characteristic of most European medical schools. On the positive side were well-informed, up-to-date faculties and the thoughtful planning and organization of graduate and postgraduate medical education. The overall impression was a favorable one, but the system of schooling and of evaluation of students' work made it possible for indifferent students to progress to licensure.

Education, Medical↗
PubMed1998

Bilateral Poland anomaly.

Bilateral absence of the pectoralis major muscle with accompanying abnormalities of shoulder muscles has been reported in patients without Poland anomaly (PA). However, symmetric absence of pectoralis major muscles, hypoplasia of breasts and nipples with symmetric chest wall deformity and bilateral hand anomaly has not previously been reported. A 6-year-old girl with bilateral absence of pectoralis major muscles and hand involvement and symmetric chest wall deformity is, to our knowledge, the first known case of bilateral Poland anomaly.

Breast↗
PubMed1998

Financing health services in Poland: new evidence on private expenditures.

This paper estimates total expenditure on health care in Poland in 1994 and provides new evidence on high levels of private spending on health care. The analysis shows that health care expenditures in Poland are higher than has usually been maintained, and are comparable with the prevailing levels in many other European countries. Private expenditure on health is a significant proportion of total expenditure on health, and in particular on financing outpatient care. Available evidence indicates that informal payments made by patients to physicians contribute as much as double of the physician's salary, and thus form an important source of earnings for physicians. This situation of high private expenditures on health care and informal payments to physicians is likely to be true of other transitional economies of Central and Eastern Europe as well. One policy implication that emerges is these transitional economies face a big challenge in managing existing resources, as opposed to finding new resources, in the health sector more effectively to meet the health care needs of their population. The paper highlights the need for better understanding of the current availability and distribution of resources in the health sector and their directions of flow, in both public and private sectors, and suggests using tools such as National Health Accounts to track and monitor changes in the financing of the health care system.

Adolescent↗
PubMed2002

Fe, Ca and Mg contents in selected fast food products in Poland.

The Fe and Mg contents in selected fast food products available in restaurants and fast food outlets in Poland were determined by AAS, and the Ca content by AES. The mean Fe contents in the studied fast food products were from 0.7 to 2.3 mg/100 g, or from 0.6 to 2.3 per single serving. The highest means for this element were found in a serving of hamburger (2.3 mg), fishburger (2.0 mg) and chicken sandwich (2.0 mg). The mean Ca contents in the studied products were from 11.6 to 192.2 mg/100 g, or 10 to 192.2 mg per serving. The highest means for this element were found in a serving of pizza (192.2 mg) and cheeseburger (134.8 mg). The mean Mg contents in the studied products were from 6.8 to 34.1 mg/100 g1 or 5.9 to 37.3 mg per serving. The highest means for this element were found in a serving of french fries (37.3 mg), chicken sandwich (34.7 mg) and fishburger (30.4 mg). Based on the Fe, Ca and Mg contents found in these products, the percentage of the Recommended Dietary Allowance (RDA) of these elements was calculated for one serving of each product. These calculations were done for various groups of people in Poland. The highest percentage of the recommended Fe intake could be covered by one serving of hamburger (15-23% RDA), fishburger (14-20% RDA), or chicken sandwich (13-20% RDA). The highest percentage of the recommended Ca intake could be covered by one serving of pizza (17-24% RDA) or cheeseburger (12-17% RDA); and for Mg one serving of french fries (11-19% RDA), chicken sandwich (10-17% RDA), or fishburger (9-15% RDA). From the conducted studies it may be concluded that some fast food products can serve as a source of Fe, Ca and Mg in the diet of people of various ages.

Adolescent↗
PubMed2003

Poland anomaly--report of an unusual family.

A family with classical Poland anomaly presenting in the son and a partially affected mother is reported. We hypothesize that Poland anomaly has a multifactorial basis involving vascular compromise in early development. Two possible predisposing factors are aberrant vascular formation and thrombophilia. The investigation of our family has not demonstrated an abnormality in coagulation, therefore, we surmise that an inherited structural variant of blood vessel formation is responsible.

Family Health↗
PubMed2004

Severe congenital myopathy with Möbius, Robin, and Poland sequences: new aspects of the Carey-Fineman-Ziter syndrome.

We report a boy with severe congenital myopathy, Möbius-Poland sequence, Robin sequence, and severe developmental delay. We consider this patient to have Carey-Fineman-Ziter syndrome. Since this is only the seventh case reported, this case helps to define further the consistent manifestations of this recognizable phenotype. Additionally our patient shows laryngostenosis, intermittent episodes of high blood pressure and Poland sequence as important clinical symptoms.

Abnormalities, Multiple↗
PubMed2003

BRCA1 and BRCA2 mutation analysis in breast-ovarian cancer families from northeastern Poland.

Sixty high-risk breast and/or ovarian cancer families from North-Eastern Poland were screened for germline mutations in BRCA1 (MIM# 113705) and BRCA2 (MIM# 600185), using a combination of protein truncation test, denaturing high-performance liquid chromatography and direct sequencing. Sixteen (27%) of the families were found to carry nine different BRCA mutations, including 14 families with BRCA1 mutation and two families with BRCA2 mutation. The results suggest the presence of two strong BRCA1 founder mutations in the Polish population - 5382insC (6 families) and 300T>G (Cys61Gly; 3 families). The remaining seven mutations were found in single families and included three previously reported BRCA1 mutations (185delAG, 2682C>T [Gln855Ter] and 3819del5), a novel BRCA1 mutation (IVS14+1G>A), as well as two BRCA2 mutations (4088delA and 7985G>A [Trp2586Ter]) not previously observed in Polish families. We confirm the strong influence of two Central-Eastern European BRCA1 founder mutations in familial breast and/or ovarian cancer in Poland. We also conclude that the Polish population has a more dispersed BRCA mutation spectrum than had been earlier thought. This warrants further careful BRCA mutation screening in order to optimise genetic counselling and disease prevention in affected families.

Adult↗
PubMed1986

A case-control study of dietary factors and stomach cancer risk in Poland.

We report results from a case-control study on stomach cancer conducted in 1980-81 in Cracow, Poland, where the risk of this disease is among the highest reported world-wide. One hundred and ten cases from a surgical clinic were matched by age and sex to the same number of controls from the same hospital. A matched series from a population-based health survey was also considered. After adjusting for residency, smoking and various food items, cases and hospital controls showed significant differences in consumption of fruits (RR rarely vs. daily: 3.24; 95% CI: 1.56-6.77), joint consumption of vegetables, salads and fruits (RR low vs. high: 4.23; 95% CI: 1.41-12.63), and consumption of protein-containing foods (RR low vs. high: 0.23; 95% CI: 0.08-0.61). Consumption of strong alcoholic beverages on an empty stomach (before breakfast) was associated with an RR of 2.09 (1.04-4.22). The findings are discussed in relation to the apparent urban/rural difference in stomach cancer incidence in Poland and the possible underlying etiological factors involved.

Aged↗
PubMed2005

Hepatotoxic cyanobacterial blooms in the lakes of northern Poland.

The lakes of northern Poland are among the recreational sites most valued by Polish and German holiday makers. Given the socioeconomic importance of these lakes, water quality should be maintained at high levels for such intensive recreational purposes. In 2002 studies of species composition, biomass, and toxin production by phytoplankton and the attendant physicochemical variables were performed in order to assess the risk of cyanobacterial blooms in selected northern lakes: Lakes Jeziorak, Jagodne, Szymoneckie, Szymon, Taltowisko, Siecino, and Trzesiecko. The research showed that total phosphorus (0.1 mg P/L) and total nitrogen (1.5 mg N/L) in the studied lakes almost exceeded the permissible limits for eutrophication of water bodies. Most phytoplankton samples were taken in late summer, when cyanobacteria were expected to reach their highest biomass. At the time of sampling most of the lakes were dominated by oscillatorialean and nostocalean species. Average chlorophyll-a concentration was higher than 10 microg/L in almost all the lakes studied, which corresponded with an average microcystin concentration in the range of 4-5 microg/L. The main microcystins in the analyzed samples were dmMC-RR, MC-RR, MC-YR, and MC-LR. The results demonstrated a potential for intensive cyanobacterial blooms to appear during the summer in northern Polish lakes. The levels of cyanobacteria found in the lakes investigated indicated that toxicity had reached the first-alert level according to World Health Organization recommendations. If microcystin-producing cyanobacteria dominate, with a microcystin concentration of 2-4 microg/L, symptoms of toxicity can appear in the swimmers most sensitive to exposure. Analysis of cyanobacterial assemblages in northern Polish lakes also indicated a significant presence of Aphanizomenon species including a Scandinavian species, A. skujae (Skuja) Kom.-Legn. & Cronb. Future investigations of Polish lakes also should assess neurotoxins and study the biology of their producers. This study was the first attempt to evaluate the potential danger of toxic cyanobacterial blooms in the lakes of northern Poland.

Bacterial Toxins↗
PubMed1994

Cuticular hydrocarbon composition and phenotypic variability in sympatric populations of Ixodes ricinus ticks from Poland.

Gas chromatography of cuticular hydrocarbons was used to assess genetic similarity and heterozygosity between 18 sympatric populations of adult Ixodes ricinus ticks collected from Poland. Sixteen n-alkanes, 45 monomethylalkanes, and 36 dimethylalkanes were identified. Forty-one compounds were detected in 90% of the specimens and nine hydrocarbons were present in all the specimens studied. Visual inspection of chromatograms revealed major differences in the relative abundance of hydrocarbons between populations of I. ricinus. The average proportion of heterozygotic hydrocarbons was 50.68%, while the average genetic similarity among all populations was 0.967. Two other methods were used to measure the intrapopulation variability: the number of isomeric forms for each hydrocarbon and the range of hydrocarbon abundance. It was found that some hydrocarbons manifested an unexpectedly high number of isomeric patterns, such as nonacosane (21 patterns), triacontane (23), pentacosane (26), and hexacosane (28). Our data suggest that I. ricinus ticks from Poland consist of several interbreeding, non-isolated populations, with a high degree of genetic flow between them.

Animals↗
PubMed1996

Respiratory symptoms in children of Upper Silesia, Poland cross-sectional study in two towns of different air pollution levels.

In children aged 7-9 years residing in the town of Chorzow (C) and in the town of Mikolow (M), located 30 km apart (Upper Silesia, the industrial part of Poland), respiratory symptoms were ascertained according to the parental answers to WHO-Questionnaire. Mean annual concentrations of air pollutants are higher in Chorzow than in Mikolow, and recent mean values of 24 hr measurements over November 1992-January 1993 confirmed the between-town gradient (p < 0.001) for particulates (C:166 micrograms/m3); M:129 micrograms/m3), SO2 (C:153 micrograms/m3); M:92 micrograms/m3) and NO2 (C:69 micrograms/m3); M:26 micrograms/m3). In Chorzow 24.8% (n = 1,142) and in Mikolow 25.6% (n = 480) of all eligible children aged 7-9 years were examined. Both groups (C and M) were similar in terms of sex, family history of asthma and cough lasting for 3 months (C:31.6%; M:32.3%). Frequency of the following respiratory symptoms statistically significantly (p < 0.05) differed between two groups: chest wheezing (C:21.4%; M:17.1%) and attacks of asthmatic dyspnea (C:10.3%; M:6.2%). Also, the diagnosis of asthma by physician was more prevalent in Chorzow (C:3.5%; M:1.3%; p < 0.05). Logistic regression analysis showed that after controlling for family history of asthma, environmental tobacco smoke and housing condition, the place of residence (C versus M) was statistically significantly associated with attacks of asthmatic dyspnea (p < 0.05) and a "borderline' significance of this factor was found in relation to wheezing (p = 0.06) and physician-diagnosed asthma (p = 0.07). The survey provided the estimate of the prevalence of chronic respiratory symptoms in children living in the most polluted urban area of Poland. Although the design of the study precludes more specific etiologic conclusions on environmental exposures the apparently higher prevalence of symptoms in children living in a more polluted town deserves further investigation.

Air Pollutants↗