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PubMed2005

Third molars associated with periodontal pathology in older Americans.

PURPOSE: The study goal was to assess the association between the presence of visible third molars and periodontal pathology in a community-dwelling sample of middle-aged and older adults. MATERIALS AND METHODS: Data were obtained between 1996 and 1999 on 6,793 persons aged 52 to 74 from the Dental ARIC Study, a substudy of the Atherosclerosis Risk in Communities Study. The main independent variable was presence or absence of third molars assessed visually, and the dependent variable was assessment of periodontal disease as measured by pocket depth of 5 mm or greater (PD5+). Periodontal measures included pocket depth, gingival recession, and attachment level on 6 sites per tooth on all remaining teeth. Second molars were compared for periodontal pathology based on the presence or absence of a visible third molar in the same quadrant. Associations were determined using odds ratios and 95% confidence intervals. Weighted multivariable models were fit using logistic regression, and variances were adjusted to account for the clustering of quadrants within persons with the use of SUDAAN (Research Triangle Institute, Research Triangle Park, NC). RESULTS: A visible third molar was associated with 1.5 times the odds of PD5+ on the adjacent second molar, while controlling for other factors associated with the presence of third molars and periodontal disease. Other factors positively associated with PD5+ in the model were male gender, older age, smoking, and irregular and episodic dental visits. CONCLUSIONS: The finding of more severe periodontal conditions associated with visible third molars in these middle-aged and older adults indicates that third molars may continue to have a negative impact on periodontal health well into later life. The relationship between third molars and periodontal disease pathogenesis deserves further study using longitudinal data.

Black or African American↗
PubMed2000

Enamel thickness and the helicoidal wear plane in modern human mandibular molars.

Helicoid occlusion has long been recognized as a feature characterizing the human dentition and has been viewed as an important morphological marker in the transition from Australopithecus to Homo. The hallmark of helicoidal wear is a buccal wear slope in anterior mandibular molars (and a corresponding lingual slope of wear in anterior maxillary molars) reversing to a flat or lingual-oriented one in posterior mandibular molars. If localized increases in enamel thickness are taken as evidence of an adaptation to increased wear resistance, then data on enamel thickness in unworn molars can be used to assess whether the region of greatest wear changes from anterior to posterior in such a way as to provide evidence for the helicoidal wear plane being a structural feature of the orofacial skeleton. Such a hypothesis was supported in a previous study on enamel thickness in modern human maxillary molars. As maxillary and mandibular precisely interdigitate, it is reasonable to expect that a similar pattern of enamel thickness distribution should be present in mandibular molars. To test this, data on the distribution of enamel thickness across functionally relevant regions of the crown were collected on a sample of twenty-nine completely unworn mandibular molars. Results suggest that enamel thickness increases slightly posteriorly but no evidence exists for morphological changes along the mandibular molar series of modern humans to follow a trend towards providing additional tooth material in areas under greater wear in accordance with a helicoidal wear model. This suggests that the patterning of enamel thickness must be viewed in conjunction with other features, such as the biomechanical behaviour of molars during occlusion and axial molar angulation, to ascertain the precise anatomical determinants of this unique feature of the human dentition.

Biomechanical Phenomena↗
PubMed1997

Effect of early restorations of permanent molars on filling increments of individual teeth.

OBJECTIVES: The purpose of this work was to analyse longitudinally whether the placement of restorations on permanent molar teeth immediately after their eruption results in (a cohort with) higher filling increments in all individual teeth thereafter. The patient documents of 937 subjects born either in 1970-1971 or in 1980-1981 were analysed. METHODS: The methods of survival analysis were employed. If any of the first permanent molar teeth had been restored in the course of tooth emergence, the person was assigned to the experimental group, and all the others were placed in the control group. Those in whom all the first permanent molar teeth had been restored at the time of emergence were compared with all the others. RESULTS: Early restoration of any permanent molar indicated higher filling increments in all the other molar teeth. The differences between the groups with regard to the first and second molar teeth were statistically highly significant (e.g. D.17 for the girls: log-rank chi 2 = 32.8, p = 0.0001 and Wilcoxon chi 2 = 28.7, p = 0.0001). The differences were greater among the girls than among the boys. Early restoration of the first permanent molar teeth did not indicate high filling increments in the incisors, canines or the smooth surfaces of any tooth. CONCLUSION: Fissure caries and smooth surface caries are different entities. The present method can be of help as an additional tool to help the clinician identify "risk" patients, in that an early restoration in any first molar is a powerful indicator of a risk of restorations in the other first molar teeth and also the second molar teeth.

Adolescent↗
PubMed2001

On the retention and effectiveness of fissure sealant in permanent molars after 15-20 years: a cohort study.

The aim of the present study was to clinically evaluate fissure sealants on the occlusal fissures and buccal pits of permanent first and second molars after 20 and 15 years, respectively. The population consisted of 72 children, each of whom had had their four first molars sealed between 1977 and 1980. At the annual examinations, all caries-free, newly erupted second molars were sealed. When sealant was applied to the second molars, the first molars were checked and sealant was reapplied to those that had deficient sealants. At the follow-up, when the subjects were 26-27 years of age, 27 in the original group had moved from the community. Thus, the present result is based on 45 subjects. One hundred and fifty-three sealed first molars and 161 sealed second molars were available for inspection. At the follow-up examination of the first molars 20 years after sealant had been applied, 65% showed complete retention, 22% partial retention without caries, and 13% caries or restoration in the occlusal fissures or buccal pits. At the 15-year follow-up of the second molars, the corresponding figures were 65%, 30%, and 5%, respectively. Of the restored or carious molars, significantly more were found in the mandible than in the maxilla (P<0.001). This longitudinal study showed that pit and fissure sealants--applied during childhood--have a longlasting, caries-preventive effect.

Adult↗
PubMed2005

Long-term clinical failure rate of molar tubes bonded with a self-etching primer.

The purpose of this study was to assess the long-term in vivo failure rate of tubes bonded to first and second molars with a self-etching primer (SEF). A total of 810 molar tubes (414 first molar and 396 second molar) were bonded on 135 patients (56 male, 79 female; mean age 14 years) with the 3M Transbond Plus Self Etching Primer. The first-time failures of the tubes were recorded for a mean period of 26 months (range 23-29 months). Failure rates per jaw (maxilla-mandible), tooth (first and second molar), and quadrant (left, right) were analyzed with the chi(2) at alpha = 0.05 level of significance. Significant differences were found in the failure rate between first and second molars (9.66% vs 20%, respectively) as well as maxillary and mandibular molars (7.5% vs 21%, respectively). The combined, total failure rate for first and second molars was 14.80%. No difference was found between male and female failure rates for the molar tubes. First-molar tubes bonded with an SEF may show failure rates comparable with those reported in the literature for tubes bonded with conventional acid etching.

Adolescent↗
PubMed2003

A preliminary in vitro study of the incidence and position of the root canal isthmus in maxillary and mandibular first molars.

AIM: To investigate in vitro the incidence and position of the root canal isthmus in extracted mesiobuccal roots of maxillary and mesial roots of mandibular first molars. METHODOLOGY: Fifty maxillary and 50 mandibular molars were included in the study. The mesiobuccal roots of maxillary molars and the mesial roots of mandibular molars were sectioned from their crowns in the furcation region and embedded in clear resin. Transverse serial 1-mm-thick sections from the apical 6 mm were prepared. The apical side of each section was stained with India ink and observed through a light microscope. The sample images were saved to disk using a digital camera and the root canals in terms of the number present and the incidence and classification of isthmuses. RESULTS: In the mesiobuccal root of the maxillary first molars, 70% had one canal, whereas 29.5% had two canals. In the mesial root of mandibular molars, 41% had one canal, whereas 59% had two canals. In some sections, more than two canals were found close to the apical foramen. The isthmus incidence was greatest 3-5 mm from the apex. In teeth having two canals, a complete or partial isthmus was frequently observed in the sections between 3 and 4 mm from the apex. Of the isthmuses present, 22% were complete and 37% partial in mandibular molars and 17.3% were complete and 11.7% partial in maxillary molars. CONCLUSIONS: The incidence of isthmus in the mesiobuccal root of the maxillary first molars and in the mesial root of the mandibular first molars was high, particularly in sections 3-5 mm from the apex. Cleaning the isthmus is a major challenge during root canal treatment.

Dental Pulp Cavity↗
PubMed2003

Incidence of patent furcal accessory canals in permanent molars of a Turkish population.

AIM: To determine the incidence of patent furcal accessory canals in permanent molars of a Turkish population. METHODOLOGY: Two-hundred extracted teeth consisting of 50 maxillary first molars, 50 maxillary second molars, 50 mandibular first molars and 50 mandibular second molars from Turkish patients attending the Oral Surgery Department of the Faculty of Dentistry, Istanbul University, Istanbul, Turkey, were included in the study. After preparation of access cavities and removal of pulp tissue, the teeth were stored in 5.25% sodium hypochlorite for 1 h. Following double-sealing of the access cavities, all tooth surfaces except the furcation regions were covered with nail varnish. The teeth were stored in 0.5% basic fuchsin for 1 week. The teeth were sectioned at the cemento-enamel junction and the presence of patent furcal canals was established by examining the pulp chamber floor with a stereomicroscope (10x) to determine staining. RESULTS: Patent furcal accessory canals were detected in 24% of maxillary first molars, 16% of maxillary second molars, 24% of mandibular first molars, and 20% of mandibular second molars. No statistically significant differences were found between the tooth types. CONCLUSIONS: In a Turkish population, the incidence of patent furcal accessory canals on the pulp chamber floor of maxillary and mandibular first and second molars ranged between 16 and 24%.

Dental Pulp Cavity↗
PubMed2000

Evaluation of the Jones jig appliance for distal molar movement.

The purpose of this study was to determine the effects of the Jones jig appliance on distal movement of maxillary molars and reciprocal effects on premolars and maxillary incisors. Cephalometric radiographs before and after orthodontic treatment of 72 consecutively treated patients, 46 females and 26 males, were measured to define treatment changes attributed to the Jones jig. Comparative measurements were made on a matched sample of 35 patients (20 females and 15 males) treated with cervical headgear by the same clinician. Both series of patients were treated to correct an Angle Class II molar relationship. The molar correction in the Jones jig patients consisted primarily of molar distal movement. Dental, soft tissue, and skeletal changes were evaluated and compared for significant differences between techniques. The results from the Jones jig sample showed the mean maxillary first molar distal movement was 2.51 mm, with distal tipping of 7.53 degrees. The mean reciprocal mesial movement of the maxillary premolar was 2.0 mm, with mesial tipping of 4.76 degrees. The maxillary first molar extruded 0.14 mm; the maxillary premolar extruded 1.88 mm. The maxillary second molars were also moved distally 2.02 mm and tipped distally 7.89 degrees. The longitudinal assessment (initial to completion of orthodontic treatment) showed significant differences between the Jones jig sample and the cervical headgear sample for lower lip to E-line and SNA. The Jones jig sample showed a mean decrease in lower lip to E-line of 0.25 mm versus 1.20 mm (P < .0212) for the headgear sample. SNA decreased 0.40 degrees for the Jones jig sample versus 1.20 degrees (P < .0093) for the headgear sample. However, the Jones jig sample and cervical headgear sample did not show significant differences of the final position in either linear or angular measurements of the maxillary first molars and corresponding premolar-incisor anchor units. The Jones jig appliance demonstrated treatment results comparable with those of the sample treated with cervical headgear. The Jones jig sample demonstrated effective distal molar movement and maintenance of the Class I molar relationship. Advantages of the Jones jig include minimal dependence on patient compliance, ease of fabrication, and ease of buccal force application.

Adolescent↗
PubMed2006

Unilateral molar distalization with a modified slider.

Although there are numerous publications on bilateral non-compliance molar distalization appliances, there is limited information on problems such as asymmetrical unilateral Class II malocclusions. The aim of the present investigation was to examine the distalization of molars unilaterally in patients with a unilateral Class II molar relationship utilizing a Keles Slider, designed without a bite plane. Ten girls (mean age 13.94 +/- 2.13 years) and seven boys (mean age 13.12 +/- 1.51 years) comprised the study material. Following insertion of the appliance, the patients were seen monthly and the screw was reactivated every 2 months. After a super-Class I molar relationship was achieved, the appliance was removed and the molars were stabilized with a Nance appliance for 2 months before the second-phase of orthodontic treatment. The Nance appliance was maintained in the palate until the end of canine distalization. Lateral cephalometric radiographs were obtained before and immediately after insertion of the molar distalizer. The results showed that the maxillary first molars were distalized bodily on average by 2.85 mm. The maxillary first premolars moved forward bodily 2 mm and were extruded 2.03 mm. In all, 1.32 mm of protrusion, 1.12 mm of extrusion, and 1.79 degrees of proclination of the upper incisors were observed. The mandibular incisors and mandibular molars erupted 0.83 and 0.95 mm, respectively. The unilateral Keles Slider distalized molars successfully to a Class I molar relationship.

Adolescent↗
PubMed2006

Primary retention of first permanent mandibular molars in 29 subjects.

This study consisted of two parts: the first part describes the aetiology behind primary retention of first permanent mandibular molars by comparing the affected molar region with the contralateral region, and the second the follow-up of the retained molars. The material comprised dental pantomograms from 29 patients (17 males and 12 females; aged 6 years 2 months to 12 years 5 months) which were sent by Danish public dental clinics to the Department of Orthodontics at Copenhagen Dental School for treatment guidance (Part 1). Questionnaires were later sent to the dentists for follow-up information regarding the affected teeth (Part 2). Part 1-aetiological evaluation: From each radiograph, the number and location of the molars, maturity of individual molars, and deviations from normal morphology were recorded. The findings showed that, in an affected region, disruption of normal dental development and eruption had occurred, causing a delay in dental maturity as well as arrested eruption of the first molar. Part 2-follow-up of eruption: Completed questionnaires and radiographs were returned for 25 subjects. In 10, eruption had occurred, six after surgical removal of mucosa covering the retained first molar. In eight patients the molar had been removed while in seven the observation time from first diagnosis was too short to evaluate eruption. The results indicate that retained first permanent mandibular molars have the ability to erupt and suggest that a unilaterally retained first permanent mandibular molar may represent a temporary delay in eruption rather than permanent failure.

Child↗
PubMed1998

Two canals in mesiobuccal roots of maxillary molars.

The purpose of this study was to examine extracted root canal treated maxillary molars cleared for: (i) the presence of a mesiopalatal (MP) canal in both first and second molars, (ii) the extension of MP canal from the pulp to the apical area, and (iii) the incidence of two foramina in the MB root. Seventy-two extracted maxillary molars (42 first and 30 second molars) were root canal treated by graduate students. The mesiobuccal (MB) roots of these samples were rendered transparent using a clearing technique. The results demonstrated that 52.3% of first and 40% of second molars had two canals obturated in the MB root. After clearing the same roots, the presence of MP canals rose to 80.9% and 66.6%, respectively. The MP canals were root canal treated as far as the foramen in 35.2% of first and 35% of second molars. However, after making them transparent, 91.1% and 90% showed the presence of this canal to the anatomical apex. The MB roots of the root canal treated first molars showed the presence of two foramina in 47% of cases but in 88.2% after clearing. The second molars showed 50% and 70%, respectively. The differences between root canal treated teeth before and after clearing were significantly different in almost all comparisons in both first and second molars. The only exception was when the presence of two foramina was compared before and after the clearing process in second molars (McNemar test P < 0.05).

Coloring Agents↗
PubMed1993

Periodontopathic bacteria and salivary microbes before and after extraction of partly erupted third molars.

This study examines the effect of extraction of third molars on suspected periodontopathogenic microbes, salivary acidogenic bacteria, and yeasts. The subjects were 39 healthy conscripts aged 20.2 yr, with symptom-free, partly erupted mandibular third molars. Microbial samples were taken from the mandibular third molar pericoronal space and from the adjacent gingival pocket of the second molar. The samples were stained by Gram's and Giemsa's methods and studied under a light microscope. Stimulated saliva was collected for assessing mutans streptococci, lactobacilli, and yeast counts by chair-side kits. All partly erupted third molars were extracted from 20 test subjects; 19 control subjects were left untreated. Microbial samplings were repeated 2 and 5 months postoperatively. Results showed that at base line the total number of Gram-negative bacteria, Gram-negative rods, and spirochetes was significantly higher at the third molar than at the second molar sites. The extraction of the third molars caused a significant decrease in the percentage of these bacteria at the second molar sites. High counts of salivary mutans streptococci (CFU > or = 10(6)) and lactobacilli (CFU > or = 10(5)) were also significantly less frequent after the operations. Yeast counts were not affected by the extractions. Thus, partly erupted third molars may harbor a periodontally pathogenic microflora and increase the number of salivary acidogenic microbes.

Adult↗
PubMed2004

Selectively preventing development of third molars in rats using electrosurgical energy.

BACKGROUND: Third molars are teeth with questionable value. People who never develop third molars avoid confronting the disease and pain these teeth often cause. Since third molars do not begin to develop until children are approximately five years of age, a window of opportunity exists to therapeutically prevent this tooth's development. The dentition of neonate rats possess developmental stages of molars similar to that of five-year-old children. This pilot study tests the hypothesis that third molars can be selectively prevented from developing. METHODS: Thirty-three neonate rats received a momentary pulse of electrosurgical energy to one of their maxillary tuberosities. The tuberosities on the contralateral sides received no treatment. Intraoral and radiographic examinations of sacrificed animals occurred when they were between 47 and 52 days old. Several tuberosity areas from sacrificed animals underwent histologic examination. RESULTS: Ten rats showed no intraoral or radiographic evidence of third molar development, and six developed smaller-than-normal third molars. Development of the maxilla also was affected frequently. One treated tuberosity area that was missing a third molar showed no histologic evidence of tooth-forming tissues, cyst formation or other significant abnormal tissue changes. CONCLUSIONS: Maxillary third molars can be selectively prevented from developing in rat pups at or near the time of tooth bud initiation; however, electrosurgical energy is too powerful and uncontrollable to reliably confine its damage to only the tooth-forming tissues. CLINICAL IMPLICATIONS: Third molars may be able to be selectively prevented from developing in growing children near the time of tooth bud initiation if less-differentiated precursor tooth-forming tissues can be selectively targeted.

Animals↗
PubMed1987

Relationship between periodontal furcation involvement and molar cervical enamel projections.

A total of 78 individuals ages 21 to 61 years with periodontal furcation involvement was examined for the presence of cervical enamel projections on the buccal surfaces of molar teeth. The furcal defects and cervical enamel projections (CEPs) of molars were diagnosed by probing, periapical roentgenographs, flap operation and inspection. Plaque index (PlI) and gingival index (GI) were recorded for the buccal and lingual surfaces of molars examined. The percentage of CEPs in the 78 individuals examined was 67.9%. The prevalence of CEPs in all molars examined was 45.2%. The prevalence of CEPs in molars with and without furcal involvements were 82.5% and 17.5%, respectively. The frequency of CEP in molars occurred in the following order: mandibular first molars, maxillary first molars, mandibular second molars and maxillary second molars. Statistical analyses (Chi-square test) revealed a significant difference between periodontal furcation involvements and the presence of CEPs. Results of this study also indicated that the furcal involvements with CEPs were associated with poor oral hygiene as measured by GI and PlI.

Adult↗
PubMed1993

The relationship between restoration and furcation involvement on molar teeth.

The purpose of this cross-sectional study was to examine the correlation between the presence of a crown (CR) or a proximal restoration (RE) and furcation involvement (FI) on molar teeth. Data were collected from 134 periodontal maintenance patients who had restored and non-restored molars present both with and without FI. A majority of the restorations that were present in these patients had been in place for at least 5 years prior to the study. First and second molars were examined clinically using the following criteria: CR, RE, FI, mobility (MO), and probing periodontal attachment level (AL). Data were analyzed with a statistical program utilizing Pearson chi-square and the pair-difference t test. The results indicated that molars with CR or RE had a significantly (P < 0.01) higher percentage of FI but no greater mobility when compared to molars without restorations. Mean probing periodontal attachment loss was greater for restored than non-restored molars but only with marginal significance (P = 0.051). There was a greater difference in mean AL between restored versus non-restored maxillary molars than for mandibular molars. This cross-sectional study provides evidence that molars with crowns or restorations involving the proximal tooth surfaces had a higher prevalence of FI and greater AL than molars without restorations.

Chi-Square Distribution↗
PubMed1997

Cervical enamel projection and intermediate bifurcational ridge correlated with molar furcation involvements.

In this study, we investigated the cervical enamel projection (CEP) and intermediate bifurcational ridge (IBR) correlated with localized molar furcation involvement (FI). Study samples consisting of 87 hopeless permanent mandibulars (56 first and 31 second molars), which required extraction for periodontal therapy, were randomly collected from the School's Dental Clinic. The furcal defects, CEPs, and IBRs of molars were diagnosed via clinical probing, periapical radiographs, and inspection of ground tooth sections of extracted teeth with a stereomicroscope. Prevalence and distribution of molars with CEPs and/or IBRs were also analyzed. Probing depths (PD), clinical attachment loss (CAL), gingival index (GI), and plaque index (PLI) were measured for the buccal and lingual surfaces of molar furcal areas. Moreover, the relationships between the molar FI with and without CEPs and IBRs and periodontal status were analyzed using Student's paired t-test. Based on those results, we can conclude the following: 1) among 87 molars with FIs examined, 63.2% (55/87) had cervical enamel projections and bifurcational ridges, and the prevalence was greatest in mandibular first (67.9%, 38/56) and second (54.8%, 17/31) molars; and 2) the differences in mean PD, CAL, PLI, and GI between the molars with and without CEPs and IBRs were highly significant (P < 0.001) in the mandibular first and second molars.

Coloring Agents↗
PubMedDate not supplied

Vertical position, rotation, and tipping of molars without antagonists.

PURPOSE: There has been a general belief that permanent teeth without antagonists overerupt, creating, after some time, considerable clinical problems. However, very few studies in the literature support this statement. The purpose of this investigation was to examine the position of molars that had been unopposed for a long period and to test the hypothesis that overeruption does affect every tooth without an antagonist. MATERIALS AND METHODS: Fifty-three individuals were examined clinically, and dental casts were taken to evaluate the position of unopposed molars. There were 84 molars (61 in the maxilla and 23 in the mandible) with a documented period of at least 10 years without antagonists. Among these teeth, 25 molars had neither an antagonist nor a mesially adjacent tooth. A qualitative method was used to evaluate the position of the molars in the vertical direction: (1) teeth with no sign of overeruption, (2) teeth with slight overeruption (< 2 mm), and (3) teeth with moderate to severe overeruption (> or = 2 mm). RESULTS: Of the 84 molars examined, 15 teeth (18%) revealed no signs of overeruption, 49 teeth (58%) displayed overeruption of less than 2 mm, and 20 teeth (24%) showed moderate to severe overeruption. Individuals with molars that had lost their antagonists in adult age had a lower risk for overeruption than the other subjects examined. The existence of adjacent teeth was important for the position of the unopposed molar in a mesiodistal or buccolingual direction. Molar rotation was more frequent in the maxilla, whereas tipping was more common in the mandible. CONCLUSION: It is concluded that not all molars without antagonists overerupt, not even in a long-term perspective.

Adult↗
PubMed2001

[The effect of the hyper-erupted third molar on chewing movement].

OBJECTIVE: To investigate the effect of the hyper-erupted third molar contacting closely to the distal surface of the opposing second molar on the chewing movement. METHODS: Twenty-three university student volunteers, 11 with hyper-erupted third molar teeth and 12 with normal occlusion, were enrolled in present study. There were totally 6 unilateral hyper-erupted third molars (3 upper and 3 lower) and 5 bilateral hyper-erupted third molars (1 bilateral upper and 4 bilateral lower). No other significantly abnormal occlusal phenomenon was observed. Five gum-chewing cycles masticated with an each side were separately recorded by means of K6-I mandibular kinesiograph (MKG) and the chewing cycles were analyzed. Both three-dimensional amplitudes and the related velocities were automatically documented with the instrument. RESULTS: (1) The chewing graphs recorded on both frontal and horizontal planes in controls were typically smooth cycles with clearly occlusal phase tracings. On the sagital plane the opening and closing traces around intercuspal position (ICP) were usually overlapped with each other. (2) 63.6% frontal cycles of the subjects with hyper-erupted third molar had an obvious table (0.2 mm to 1.0 mm in width) around ICP, 50% horizontal cycles of the subjects had a 0.2 mm to 0.5 mm step near to ICP, 72.7% opening and closing traces on the sagital plane separated into anterior and posterior branches. The abnormal traces on the three different planes of the hyper-erupted third molar tooth group appeared to be related each other, implying that they might be caused by the same characteristics of occlusion, namely, the hyper-erupted third molar. (3) Subjects with hyper-erupted third molar masticated in more posterior direction, together with a higher chewing terminal velocity. CONCLUSIONS: The hyper-erupted third molar had a significant effect on the chewing cycles around ICP, as well as on the amplitude and velocity of chewing movement.

Adolescent↗