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At least 343 records · Page 19Linked to original sources

Early management of severe head injury in Northern Ireland.

As part of a study into the management of major trauma, the early management of severe head injury in Northern Ireland was evaluated over a 12-month period. The injury severity score was used to define those patients considered to have severe head injury. There were 131 patients with severe head injury; 27 per cent were hypoxic and 18 per cent were hypotensive on admission to the primary hospital. Almost half had severe multiple injuries. Early endotracheal intubation was performed in 92 per cent of comatose patients, and adequate resuscitation (including laparotomy in some) was performed in 87 per cent of shocked patients transferred to the neurosurgical unit (NSU). Eighty patients were transferred to the NSU; 60 per cent were comatose, 68 per cent were intubated and ventilated, and 74 per cent were transferred by an anaesthetist. Two patients were in hypovolaemic shock after transfer and required laparotomy. Thirty-eight had evacuation of an acute intracranial haematoma; 26 of these would not have been classified as severe head injury by the Glasgow coma scale. The overall mortality rate was 38 per cent, and 24 per cent for those transferred to the NSU. We conclude that the early management of head injury in Northern Ireland is good, but there are problems, including pre-hospital oxygenation and delays in transfer.

Adolescent↗

Tissue concentrations of organochlorine compounds in common seals from the coast of Northern Ireland.

An epizootic of morbillivirus infection killed several hundred common seals (Phoca vitulina) along the coast of Northern Ireland in 1988. Many dead and moribund seals were submitted to the Department of Agriculture for Northern Ireland, Veterinary Research Laboratories for necropsy. Samples of blubber, liver and kidney were collected from these animals (n = 55) for analysis for a wide range of organochlorine pesticides and also total polychlorinated biphenyls (PCBs). The organochlorines found in highest concentrations in blubber were PCBs which were detected in all samples (mean, 26 micrograms g-1 wet wt). sigma DDT (mean, 2.63 micrograms g-1 wet wt) and chlordane (mean, 0.22 micrograms g-1 wet wt) were also present in all samples. Heptachlor including heptachlor epoxide (mean, 0.13 micrograms g-1 wet wt) was present in over 93% of samples. Seventy-four percent of samples contained alpha HCH (mean, 0.035 micrograms g-1 wet wt), 50% contained beta HCH (mean, 0.026 micrograms g-1 wet wt) while gamma HCH (mean, 0.012 micrograms g-1 wet wt) was detected in 46% of samples. The organochlorine concentrations found in this study are at the lower end of the range previously reported for European common seals.

Adipose Tissue↗

Acinic cell carcinoma in Northern Ireland: a 10-year review.

12 cases of acinic cell carcinoma diagnosed in Northern Ireland from 1942 to 1982 on which there was at least 10 years' follow-up were reviewed, by pooling cases from all regional pathology laboratories. Clinical findings at presentation were established from case notes, together with details of eventual clinical outcome. Sections were examined to determine tumour size, morphological pattern and cytological constitution, the presence or absence of cytological atypia, mitotic activity, lymphocytic and desmoplastic responses, and to assess for infiltrative margins and adequacy of excision. The tumours arose in 8 females and 4 males, aged 22 to 86 years at presentation. Eleven tumours were in the parotid, one in the soft palate. Two patients suffered local recurrence, both more than 7 years after diagnosis. Five patients had regional lymph node metastasis, four at presentation. No patient suffered haematogenous metastasis or died of tumour. Of the features examined, incomplete excision increased the risk of local recurrence. While numbers are small, the acinic cell carcinoma in Northern Ireland is an unpredictable low-grade malignant tumour which is capable of recurrence and metastasis. Adequate excision at presentation appears to be the most appropriate therapy.

Adult↗

Health and social inequities in Ireland.

This paper attempts to discuss the shape of inequalities in health in the Republic of Ireland by focusing on social class, gender and regional inequalities in health outcomes as shown in annual publications of vital statistics and in various research studies. The Republic of Ireland has a demographic profile of rapid population increase, unique in Europe. While the birth rate is the highest in Europe, the infant mortality rate is relatively low, yet the perinatal mortality rate is relatively high. Attempts are made to analyse social class variations in mortality and morbidity rates but, except for psychiatric care, Irish data on health by social class are scarce. There exist more data on gender inequalities which pinpoint the particular vulnerability of Irish women to ischaemic heart disease and certain types of cancer. Regional analysis of vital statistics reveals the vulnerability of people in urban areas (compared to rural areas) to cancer of the trachea, bronchus and lung, cirrhosis of the liver, tuberculosis of the respiratory system, pneumonia, and bronchitis, emphysema and asthma. In comparison to several European countries, Irish standardized mortality rates were the worst for urban women dying from lung cancer, and for urban men and women, Irish standardized mortality rates were the worst for non-rheumatic heart disease and respiratory tuberculosis. Various studies of morbidity of the elderly clearly reveal the hidden clinical iceberg of symptoms which are not presented to the health care system. Unfortunately, there is relatively little evidence of the health situation of disabled people, the travelling community or the long term unemployed.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗

Child protection or professional self-preservation by the baby nurses? Public health nurses and child protection in Ireland.

An exploratory, focus group methodology was used to elicit the views of public health nurses (PHNs) on the topic of child welfare and protection in the context of new legislation and evolving child care policy in Ireland. The nurses' views were considerably at variance with the officially stated commitment to inter-disciplinary collaboration and coordination within the Community Care Programmes of Ireland's regional health boards. The PHNs feared that involvement in child care proceedings of a social control or adversarial nature would compromise them in terms of their traditional curative and preventive health roles, and, on this basis, argued that social workers should retain the bulk, if not all, of the responsibility for such child care activity. The nurses also defined their work roles in terms of their own traditional, professional commitment to individuals, families and communities, and felt less bound by or even aware of the corporate responsibility of their employing health board. It is concluded that the enactment of new legislation and allocation of additional resources do not resolve the issues of inter-disciplinary collaboration in this area.

Adolescent↗

Novel and Mediterranean beta thalassemia mutations in the indigenous Northern Ireland population.

beta thalassemia is one of the most common genetic diseases worldwide resulting from aberrant beta-globin chain production. It is highly prevalent in regions with endemic malaria, but it is also present at low frequency in the indigenous populations of non-tropical areas such as Britain. Screening beta thalassemia trait individuals from Northern Ireland has detected 2 Mediterranean mutations, 39 (C --> T) and IVS-I-110 (G --> A); the previously reported IVS-II-850 (G --> A) mutation originally described in individuals of Scottish/English ancestry; and 2 novel mutations, initiation codon A --> C and 109 delG. Haplotype analysis indicates that the Mediterranean mutations are present on previously described haplotypes, suggesting that they have arisen due to migration. It remains to be established whether the novel mutations have arisen de novo in Northern Ireland.

Adolescent↗

A dispersion modelling approach to determine the odour impact of intensive poultry production units in Ireland.

The use of atmospheric dispersion modelling has become more common for the determination of odour impacts from existing poultry production facilities and the assessment of setback distances for new facilities. Setback distances for broiler, layer and turkey units were determined using the atmospheric dispersion model ISCST3 and the Environmental Protection Agency (EPA, Ireland) recommended criterion (C(98,1-h)6.0 ou(E) m(-3)) and a new odour annoyance criterion (C(98,1-h) 9.7 ou(E) m(-3)) developed in this study. For a typical size unit in Ireland, maximum setback distances of 660, 665 and 1035 m were calculated for 40,000 broilers, 40,000 layers and 10,000 turkeys respectively at the current limit (C(98,1-h) 6.0 ou(E) m(-3)). However, if the suggested odour impact criterion (C(98,1-h) 9.7 ou(E) m(-3)) is implemented, the maximum setback distances decrease to 460, 500 and 785 m for broilers, layers and turkeys, respectively.

Animal Husbandry↗

The management of short saphenous varicose veins: a survey of the members of the vascular surgical society of Great Britain and Ireland.

OBJECTIVE: The outcome of short saphenous vein surgery is often unsatisfactory and the high litigation rate reflects this. The aim of this study was to explore the current management of short saphenous varicose veins in Great Britain and Ireland. METHODS: This was a postal questionnaire survey of the surgical members of the Vascular Surgical Society of Great Britain and Ireland. Of 532 questionnaires 379 were returned (71.2%). RESULTS: There was diversity of opinion about the management of short saphenous veins. Eighty nine per cent of surgeons requested duplex imaging for all patients and over 50% arranged additional duplex marking of the saphenopopliteal junction preoperatively. Only 10.4% formally exposed and identified the popliteal vein during saphenopopliteal ligation, the majority (75.7%) dissected down the short saphenous vein to visualise the junction. The short saphenous vein was stripped routinely by 14.5% of surgeons, the majority preferring to excise a proximal segment of up to 10 cm (55.1%). Compared with long saphenous vein surgery, surgeons were generally more likely to warn patients of nerve damage but equally likely to warn of deep vein thrombosis. A small number of surgeons failed to warn patients of these complications. CONCLUSION: The variation in management of short saphenous veins may be explained by the lack of definitive clinical trials in this area.

Data Collection↗

Developing a healthy ageing policy for Ireland: the view from below.

There is a healthy ageing programme in a place in Ireland since 1998. However, there has never been a systematic review of healthy ageing policy in the country or of the impact of the new programme on the sector. This paper uses both a quantitative and qualitative survey methodology to elicit the views of participants and stakeholders on current policy and future priorities for healthy ageing in Ireland. The data are based on extensive consultation with stakeholders in the field of healthy ageing and adheres to a participative model of research in keeping with best practice in health promotion investigation. New information is provided on the nature and structure of healthy ageing activity in the country and on the major issues for stakeholders in respect of resource allocation, priorities and best practice. The results suggest that current policy needs to be recalibrated in favour of greater public support for projects in the social environment. Overall funding also needs to be increased for the sector and genuine partnerships between policy-makers and older people need to be established. Finally, the paper reports a worrying concern among stakeholders of the deleterious effect of ageism on the participation of older people at all levels of society.

Aging↗

A discourse analysis of debates surrounding the entry of nursing into higher education in Ireland.

BACKGROUND: It was only at the start of the 21st century that the nursing profession in Ireland gained full entry to the academy, joining the ranks of the graduate professions in healthcare. Up to that time, the system of professional training of nurses in Ireland was based on the apprenticeship-training model. AIM: This paper critically analyses discourses opposing advanced educational preparation for nurses and the entry of nursing to higher education in order to reveal the discursive work they perform. METHODS: The study analyses historical and contemporary texts using a critical discursive approach. FINDINGS: The study uncovers common themes and continuities embedded in discourses concerning the role of the nurse and nurses' professional training. Through professional and popular debate, a particular and enduring set of images of the nurse was constructed, which was antithetical to the idea of a nurse receiving professional training in the academy. The debate was conducted by doctors, journalists, public officials, and by nurses, some of whom were ambivalent or even hostile to the notion of the educated nurse. Much of the debate concerned the role of the nurse and the relationship between knowledge/intelligence and practice/caring. CONCLUSIONS: As outsiders looking into the academy, nurses were required to justify their case for entry into higher education against a discursive backcloth that constructed a dichotomy between the mental and the manual and positioned nursing as a practical and commonsense occupation unworthy of academic study. In consequence, nursing was and continues to be challenged to expose, resist and counter the values and assumptions embedded in this backcloth as they strive to establish, maintain and consolidate their foothold in academia.

Attitude of Health Personnel↗

UK and Ireland experience of bone anchored hearing aids (BAHA) in individuals with Down syndrome.

OBJECTIVE: To evaluate the indications, surgical techniques and post-operative problems seen in children with Down syndrome fitted with bone anchored hearing aids (BAHA). METHODS: A postal survey of all registered United Kingdom and Ireland BAHA centres. RESULTS: There was a 98% response rate to the survey. Eighty-one centres in the United Kingdom and Ireland undertake BAHA surgery. Eighteen centres were identified to have undertaken BAHA surgery on individuals with Down syndrome. A total of 43 individuals were implanted. Twenty-four cases were under the age of 16. Soft tissue complications were encountered in 21 patients (49%). Osseointegration failures were encountered in four cases (9%). There was a high level of satisfaction with the BAHA system amongst patients, parents and carers. CONCLUSIONS: BAHA is a valuable method of hearing amplification in children with Down syndrome. It should be considered not as a primary method of amplification, but in the overall management of individuals with Down syndrome after conventional hearing aids and/or ventilation tubes have been considered or already failed. The survey shows a high patient and carer satisfaction with the system, despite short term early soft tissue complications.

Adolescent↗

Bed occupancy and turnover interval as determinant factors in MRSA infections in acute settings in Northern Ireland: 1 April 2001 to 31 March 2003.

The following data were obtained from annual hospital statistics in Northern Ireland and from the Communicable Diseases Surveillance Centre (CDSC) Northern Ireland for 2001-2002 and 2002-2003: bed turnover interval (TI), percentage bed occupancy (PO) and methicillin-resistant Staphylococcus aureus rates per 1000 bed-days of patient episodes [MRSA (PE)]. A significant negative correlation was established (r=-0.854; P<0.01) between TI and MRSA (PE) in 2002-2003. A significant positive correlation for PO and MRSA (PE) (r=0.679; P<0.05) was also found for the same year. The correlation for TI and MRSA (PE) in 2001-2002 was r=0.621 (P<0.05), but no significant correlation was established for PO and MRSA (PE) in the same year. Partial correlation indicated that the influence on MRSA (PE) rates was greater for TI than for PO. These results infer that a rapid turnover of patients is an important factor influencing MRSA rates within acute hospitals.

Bed Occupancy↗

Irish-1 and Irish-2: UK epidemic meticillin-resistant Staphylococcus aureus strains associated with Northern Ireland.

Since 1998, an increasing number of meticillin-resistant Staphylococcus aureus (MRSA) isolates with one of two characteristic phage patterns have been referred to the authors' laboratory from Northern Ireland. These strains were designated 'Irish-1' and 'Irish-2'. Analysis of 956 submitted isolates classified as Irish-1 or Irish-2 showed that 97% of the former and 95% of the latter were from Northern Ireland. Only 0.2% and 3%, respectively, were from England. Eleven Irish-2 isolates had been referred from Western Australia as representatives of an epidemic strain originally isolated there in 1994. Ninety isolates with the Irish-1 phage pattern and 91 isolates with the Irish-2 phage pattern, from numerous hospitals, were characterized by SmaI pulsed-field gel electrophoresis (PFGE), toxin gene carriage and antibiotic susceptibility. PFGE showed that, within each collection, a few isolates represented unrelated strains, but the majority were within six band differences of the most common profiles. Half of the Irish-1 isolates were homogeneous, with 22 DNA profiles among the remainder. Irish-2 isolates had two common profiles, D1 and D2, equally divided between one-third of the isolates and differing from each other by two bands; the remaining isolates shared 31 DNA profiles. Cluster analysis showed some overlap in DNA profiles between the Irish-1 and Irish-2 strains, but clear separation from other epidemic MRSA strains. There was no obvious correlation between PFGE profile and either antibiotic resistance pattern or toxin gene possession. All but three Irish-1 isolates possessed only the staphylococcal enterotoxin A (sea) gene, whereas almost all Irish-2 isolates were negative for all 12 enterotoxin genes. Sixty-nine percent of Irish-2 isolates were resistant to ciprofloxacin, erythromycin, kanamycin, neomycin and streptomycin, while 90% of Irish-1 isolates were resistant to all these plus gentamicin and mupirocin. All isolates were sensitive to quinupristin/dalfopristin, teicoplanin and vancomycin. Urease production was negative in both strains. The results suggest that Irish-1 and Irish-2 are distinct epidemic strains, identifiable by phage typing, DNA profiles, antibiotic resistance and toxin gene carriage.

Bacteriophage Typing↗

Rediscovery of Trichinella spiralis in red foxes (Vulpes vulpes) in Ireland after 30 years of oblivion.

OBJECTIVE: To determine whether or not Ireland can be considered as Trichinella-free, after more than 30 years of no reported infections in domestic and sylvatic animals and in humans. METHODS: Samples of muscle tissue from the tongue, masseter, and foreleg of red foxes (Vulpes vulpes) were subjected to artificial digestion and to multiplex-PCR analysis for identifying Trichinella larvae at the species level. RESULTS: Four of 454 examined foxes were positive for larvae (overall prevalence 0.9%). The positive foxes had been collected in Donegal County (one fox; prevalence of 7.7%), Cork County (two foxes; 3.1%), and Waterford County (one fox; 4.2%). All larvae were identified as Trichinella spiralis. CONCLUSIONS: The detection of Trichinella-positive foxes in Ireland is an example of how the lack of infections among domestic animals and humans does not suffice for establishing Trichinella-free status. The results also confirm that the sylvatic cycle can last for tens of years, independently of the existence of a domestic cycle.

Animals↗

Exercise therapy for low back pain: a small-scale exploratory survey of current physiotherapy practice in the Republic of Ireland acute hospital setting.

A small-scale exploratory cross-sectional survey investigated the current use of a range of exercise therapy approaches for low back pain (LBP) by outpatient physiotherapists in the acute hospital setting in the Republic of Ireland, where the majority of publicly funded treatment is delivered. Of the 120 postal questionnaires distributed to 24 physiotherapy departments, 87 were returned (72.5% response rate). The results showed specific spinal stabilization exercises were the most popular exercise therapy for acute (39%; n = 35) and chronic (51%; n = 48) LBP, followed by the McKenzie approach (acute LBP (ALBP) 35.6%; n = 32: chronic LBP (CLBP) 17%; n = 16), and abdominal exercise (ALBP 11.1%; n = 10: CLBP 9.6%; n = 9). The most popular forms of exercise therapy used by outpatient physiotherapists in acute hospital settings in Ireland lack support from evidence-based clinical guidelines, and further large-scale high quality randomized controlled trials of these approaches are warranted. Further research should also establish the use of exercise therapy and attitudes to clinical guidelines of physiotherapists in other countries and healthcare settings.

Cross-Sectional Studies↗

Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD.

The role of genetics in parkinsonism has been confirmed over the last decade with the identification of genetic variation in seven genes, which are causative in familial forms of the disorder. A number of pathogenic mutations have been identified in the latest gene LRRK2, with a Gly2019Ser amino acid substitution identified in two siblings and one patient with idiopathic Parkinson's disease from Ireland. The clinical features resemble the idiopathic variant with a tremor predominant clinical picture shared by the siblings, slow progression of symptoms, and no observation of cognitive disturbance in all. The family and the sporadic individual were apparently not related and originated from different regions of Ireland, although haplotype analysis does suggest they share a common founder. The influence of the G2019S substitution on protein function and disease phenotype has yet to be fully resolved, but its elucidation will undoubtedly further our understanding of the mechanisms underlying Parkinson's disease.

Adult↗

Development of public health observatories in the UK, Ireland and Europe.

Public Health Observatories are a new phenomenon in the United Kingdom and Ireland. However, similar institutions have been operating in other countries for many years. The nature and development of PHOs in England, Wales, Scotland and Ireland are described, and how they are supporting the growing public health movement in Europe is considered.

Community Health Planning↗

Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland.

In December 1999, domoic acid (DA) a potent neurotoxin, responsible for the syndrome Amnesic Shellfish Poisoning (ASP) was detected for the first time in shellfish harvested in Ireland. Two liquid chromatography (LC) methods were applied to quantify DA in shellfish after sample clean-up using solid-phase extraction (SPE) with strong anion exchange (SAX) cartridges. Toxin detection was achieved using photodiode array ultraviolet (LC-UV) and multiple tandem mass spectrometry (LC-MS(n)). DA was identified in four species of bivalve shellfish collected along the west and south coastal regions of the Republic of Ireland. The amount of DA that was present in three species was within EU guideline limits for sale of shellfish (20 microg DA/g); mussels (Mytilus edulis), <1.0 microg DA/g; oysters (Crassostrea edulis), <5.0 microg DA/g and razor clams (Ensis siliqua), <0.3 microg DA/g. However, king scallops (Pecten maximus) posed a significant human health hazard with levels up to 240 microg DA/g total tissues. Most scallop samples (55%) contained DA at levels greater than the regulatory limit. The DA levels in the digestive glands of some samples of scallops were among the highest that have ever been recorded (2,820 microg DA/g).

Animals↗