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At least 343 records · Page 19Linked to original sources
PubMed2001

Trihydroxyethylrutosides in the treatment of hemorrhoids of pregnancy: a double-blind placebo-controlled trial.

The safety and efficacy of Trihydroxyethylrutosides (HR) in the treatment of 53 patients with 1st-2nd degree hemorrhoids of pregnancy (16th-34th week) was investigated in a double-blind randomised, placebo controlled trial. The dosage of Trihydroxyethylrutosides was 1 tablet of 300 milligrams twice daily for the first 2 weeks. If the treatment was successful, the treatment was stopped. If the clinical signs or symptoms still persisted, the treatment was continued for another two weeks using the same dosage and re-evaluated at the end of the fourth week after initial treatment. The parameters for efficacy were symptoms (pain, bleeding, exudation and pruritus) and the objective signs on proctoscopy (bleeding, inflammation and dilatation of the hemorrhoidal venous plexus). The study revealed improvement of symptoms in the study group which was better than in the control group after 2 weeks of treatment but the clinical signs were not different. After a further 2 weeks of treatment, the result showed improvement of both clinical signs and symptoms in this study. Only one mild transient side effect was reported in the HR group and there were no drug-related problems in the pregnancies, delivery or the babies.

Administration, Oral↗
PubMed2002

Comparative study between multiple and single rubber band ligation in one session for bleeding internal, hemorrhoids: a prospective study.

OBJECTIVE: The aim of this study was to compare the cessation of bleeding and the complications between multiple and single ligation using high ligation technique. MATERIAL AND METHOD: All first-visit patients with bleeding internal hemorrhoids were studied and randomly divided into multiple and single ligation groups. High ligation technique was used. Patients visited the clinic in the second week and were invited to visit the clinic or completed questionnaires after one year. RESULTS: 109 patients were included in the study. 61 patients had multiple ligation and 48 patients had single ligation. The cessation of bleeding in one week occurred in 96.7 per cent of patients in the multiple group and 79 per cent of patients in the single group (p = 0.004). There were no differences between the multiple group and single group concerning postligation pain and tenesmus (6.5% vs 2%, p = 0.532), urinary hesitancy and frequency (6.5% vs 4%, p = 0.904), and rebleeding in one year (27.9% vs 34%, p = 0.710). No major complications such as massive bleeding and pelvic sepsis were noted. CONCLUSIONS: Multiple ligation of bleeding internal hemorrhoids in one session can stop bleeding better than single ligation with no more complications.

Adult↗
PubMed2002

[Using a compression method after surgical treatment of hemorrhoids].

A compression method was used as a final stage of surgical treatment of hemorrhoids which was performed with a specially worked out compressing probe (two latex cuffs were mounted on the three-lumen rubber tube). The internal and external hemorrhoids were compressed after introduction of the probe into the anal canal and blowing up the cuffs. Comparative results of 103 operations are shown: in 67 patients the operation was finished with the introduction of an ointment tampon, in 36--with a compressing probe. Postoperative results judged by such symptoms as postoperative pains, bleedings, adaptation of the operation wound edges, retention of urine etc. showed that the compression method had considerable advantages over the control group.

Adult↗
PubMedDate not supplied

[Surgical treatment of mucosal hemorrhoidal prolapse using a circular stapler].

We present a retrospective clinical study concerning our personal experience with the circular stapler in the treatment of hemorrhoids; the aim of this study was to evaluate the results of this surgical procedure, in terms of operative time, postoperative pain and rate of both short and long-term complications. Twenty-seven patients with grade 3 or 4 hemorrhoids, from January 1999 to June 2001, were included in the study. The main technical details of this procedure, requiring only a short learning period, are described and both short-term complications (such as severe postoperative pain, bleeding, urinary and fecal retention) and long-term ones (such as persistent or recurrent haemorrhoidal prolapse, anal stenosis) are analyzed. The reported results show that, in the presence of appropriate local anatomic conditions, this procedure is able to reduce the operative time, is almost painless and is characterized by low rate of complications.

Adult↗
PubMed1992

[Clinical study for the evaluation of the tolerability of O-(beta-hydroxy-ethyl)-rutoside in the treatment of hemorrhoids during the 3d trimester of pregnancy and in the postpartum period].

Hemorrhoidal disease is particularly frequent in the last trimester of pregnancy and immediately after birth. The aim of the present study was to evaluate the efficacy and tolerability of high doses of O-(beta-hydroxyethyl)-rutoside in patients affected by this pathology. Forty-two women with hemorrhoid varices of varying severity which had appeared during the last trimester of pregnancy or immediately post-partum were treated by administering 3 g/day of the substance in question for 14 consecutive days. At the start and end of treatment a series of clinical and objective parameters were measured and at the end of treatment efficacy and tolerability were assessed. The latter was found to be excellent; in fact, it was not necessary to suspend treatment in any of the subjects treated. Clinical efficacy, assessed by the researcher, was judged to be positive in 95% of cases treated. Clinical improvements in the parameters examined were statistically significant (p < 0.01). The results obtained confirm the value of oral therapy using O-(beta-hydroxyethyl)-rutoside in pregnant or puerperal patients since the preparation was found to be efficacious and easily managed, above all significantly reducing pain, subjectively the most urgent symptom to be treated.

Adult↗
PubMed1992

[Diagnosis and therapy of acute hemorrhoids].

The analysis of the results of treatment of 137 patients with acute hemorrhoids was carried out. A typical hemorrhoidal analysis was noted in 83.5% of the patients. Operated on were 129 (94.1%) patients, including 27 (20.9%)--at day 3-4 after hospitalization. Duration of hospital stay of the patients operated on after short-term preparation was 9.2 days. This figure is 4.1 days less than that in patients operated on in a delayed order.

Acute Disease↗
PubMed1992

[Ointment treatment of 1st degree hemorrhoids. Comparison of the effectiveness of a phytogenic preparation with two new ointments containing synthetic drugs].

OBJECTIVES: Investigation of the usefulness of a vegetable-based hemorrhoid ointment in comparison with two other ointments containing synthetic substances, one of which additionally contained corticoid. STUDY DESIGN: Treatment of 90 patients with first-degree hemorrhoids in the surgical department of a University Polyclinic, within the framework of a double-blind three-limb study of 21 days duration. Follow-up examinations on the third, seventh, fourteenth and twenty-first day of treatment. TARGET CRITERIA: Four typical symptoms--pruritus, bleeding, burning sensation, sore sensation--graded by both physician and patient. RESULTS: All three ointments proved highly effective. Both during the course of treatment and at the final examination carried out on the 21st day, no major differences were to be found between the three treatment groups. In the case of some of the test parameters, a positive tendency in favor of the herbal ointment was observed.

Adult↗
PubMed1992

[Local therapy of grade 1 and 2 hemorrhoids. Effectiveness of a combination preparation with standardized blood leech extract].

AIMS: Testing the effectiveness of a topical combination preparation containing standardized leech extract, polidocanol and allantoin. STUDY DESIGN: Placebo-controlled, double-blind study in 80 patients with first and second degree hemorrhoids; duration of treatment one week; examinations performed on admission and on days 3, 4, 5 and 8. RESULTS: Both the subjective and objective symptoms and signs improved during the one week of treatment statistically significantly more rapidly under the test preparation as compared with placebo. Histologically demonstrable signs of inflammation were more clearly improved in the preparation group than in the placebo group. No side effects were observed. CONCLUSIONS: The good efficacy and tolerability of a topical therapeutic preparation in first and second degree hemorrhoids have been convincingly demonstrated.

Allantoin↗
PubMed2006

[Comparison of efficacy between procedure for prolapse and hemorrhoids and open hemorrhoidectomy].

OBJECTIVE: To compare the results of procedure for prolapse and hemorrhoids (PPH) and open hemorrhoidectomy. METHODS: A standard questionnaire was given to all patients after PPH or open hemorrhoidectomy from March 2001 to March 2004. In combination with proctological examination, the results including symptoms relief and recurrence were compared between the two groups. RESULTS: There were 184 effective questionnaires, including 96 cases in PPH group and 88 in open hemorrhoidectomy group. PPH and open hemorrhoidectomy both relieved prolapse (92.7% vs 96.8%, P=0.282), bleeding (91% vs 81%, P=0.241) and pain (91.7% vs 91.5%, P=0.977). There were no statistical differences in the overall complication rate (30.2% and 29.5%, P=0.923) and recurrence rate (21.8% vs 20.5%, P=0.814) between the two groups. The overall satisfactory degree was 87.5% in PPH group and 84.8% in open hemorrhoidectomy group (P=0.218). CONCLUSION: PPH is a safe and effective option for prolapsed hemorrhoids compared with open hemorrhoidectomy.

Adult↗
PubMedDate not supplied

[Hemorrhoidal thrombosis. A clinical and therapeutical study on 22 consecutive patients].

Hemorrhoidal thrombosis (HT) represents one of the most frequent complication of hemorrhoids. The two main modalities of clinical presentation are thrombosed of a single external pile or as massive thrombosis (MT), both representing an harmfull condition for the patient which can be usually treated with surgical intervention on an outptient basis. The etiopathogenesis of the disease is nowadays obscure and few investigated till now in the international literature. The Authors performed a prospective study on 22 patients with HT aimed at clarifying the ethiopathogenesis of the disease through the evaluation of the emocoagulative profile of these patients. All the main coagulopathy indexes such as aPT, APTT, Fibrinogen, AT III, XDP, aPCR and LAC resulted normal, while the products of prothrombin degradation (F1 + F2) showed higher values in respect of the control group (p < 0.0001). Our study seems to highlight that HT could not be considered a sistemic or local coagulopathy, so far surgical management of the disease remains the gold standard, as confirmed in our series.

Adolescent↗
PubMed1991

[Post-operative evaluation of 1000 consecutive hemorrhoid cases].

From September 1983 to October 1988, one thousand consecutive hemorrhoid patients were hospitalized and treated at T.C.V.G.H.A retrospective evaluation based on their admission charts was conducted. Two surgical procedures, wedge hemorrhoidectomy and anoplasty, were compared. We collected and analyzed the following data: sex, age, surgical procedure, post-operative pain, complications and number of days of hospitalization. This study discovered that the larger the major operative area and the greater the number of suture knots, the severer the post-operative pain. For instance, anoplasties resulted in a higher incidence of urine retention (78.1%) and stool impaction (79.4%) than hemorrhoidectomies did. Early complications were found primarily in cases receiving anoplasty, but in later complications, there were no significant differences found between procedures. Anoplasty also resulted in a longer hospital stay, so when dealing with the same degree of hemorrhoid, the simpler the operation, the better the result, because the patients' discomfort can be reduced and hospitalization can be shortened.

Adult↗
PubMedDate not supplied

[Ligation and sclerosis technique combined with electrocoagulation resection of internal hemorrhoids].

We review 1331 patients who were treated by sclerosis and rubber band ligation, stepped binding, simultaneous binding and sclerosis with electrocoagulation resection as the main hemorrhoidal bundle treatment, from July 1977 through July 1990, was performed. The benefits on symptoms, complications, and final outcome were analyzed. Binding of only one hemorrhoidal bundle with sclerosis of the other two in the 74.9%, binding of two bundles with sclerosis of the other in the 13.7% and simultaneously binding of the three bundles in the 4.8% was performed. Binding, sclerosis and electrocoagulation resection of three bundles was also performed in the 6.45%.

Adolescent↗
PubMed1991

[Treatment of hemorrhoids with sclerosing solutions].

From 1968, the authors treated under ambulatory-polyclinical conditions 10,000 patients with hemorrhoids by means of injections of novocaine++-alcoholic mixtures. In 93.3% of the patients after injections, the hemorrhage stopped, in 83.8%--hemorrhoidal nodes didn't prolapse, in 95.6%--inflammation was liquidated. At the long-term period, the positive effect was noted in 8664 (92.2%) patients.

Ambulatory Care↗
PubMed1990

[The surgical treatment of hemorrhoids. Their suturing ligation without excision].

Analysis is made of the results of application of a modified method offered by the author "suturing ligature without excision" in hemorrhoids. It consists of suturing ligature of the vascular bundle, including ligation of the hemorrhoid node itself without excision. For the period 1981-1988 the method was applied on 32 patients. The results were compared with those in a control group of 105 patients operated by the method of Milligan, Morgan. The mean postoperative hospital treatment lasted 3.2 days, vs. 11.4 days in the control group. It was moreover characterized by minimal pain, good state of well-being and hygiene, normal intestinal passage from the first day with flatulence and defecation. Pain lasting more than 24 hours had only 2 patients, vs. 97 in the control group. There was no constrained retention of bowel movement, which in the control group led to difficult flatulence in 101 patients and exacerbation of colitic complaints. The method is pathogenetically substantiated. It provides ligation of the terminal branchings of a. rectalis sup. averts relapses and postoperative bleeding, preserves a sufficient mucosal surface to ensure the physiologic act of flatulence.

Hemorrhoids↗
PubMed1990

[Selection of the method of treatment of complicated hemorrhoids].

The authors make a comparative analysis of the immediate complications after hemorrhoidectomy conducted by various methods in 504 patients engaged in heavy physical work. Group 1 consisted of 172 patients with hemorrhoidectomy performed by the ligature method. Group 2 was made up of 151 patients who had been operated on by A. N. Ryzhikh's modification of Martynov's method. Group 3 included 145 patients treated by the Milligan-Morgan operation involving the restoration of the anal mucosa. Group 4 consisted of 36 patients who had undergone ligation of the terminal branches of the superior rectal artery with economical excision of the hemorrhoids. In appraisal of the results of operative treatment of hemorrhoids, the least number of complications were found in patients of groups 3 and 4.

Adult↗
PubMed1990

Infrared photocoagulation of hemorrhoids.

Twenty five patients with grade one and grade two bleeding internal hemorrhoids were treated with infrared photocoagulation. This study did not compare the different methods of treatment, however the results do support the contention that infrared photocoagulation is an effective, safe method of treatment for low grade bleeding internal hemorrhoids.

Adult↗
PubMedDate not supplied

Who me? Reduce hemorrhoids? It's not my job!

Hemorrhoids are a problem for many postpartum patients. A procedure for manually reducing hemorrhoids is outlined along with necessary patient teaching. This procedure is a nursing responsibility as long as the patient does not have other anorectal area trauma.

Female↗
PubMed1989

[Technique, procedure and value of ambulatory hemorrhoid therapy].

The treatment of piles should aim to reduce the abundant hemorrhoidal tissue in accordance with the stage (1. degree-3. degrees). In all cases an attempt should be made to regulate bowel function while avoiding straining. A high fibre diet is advised or a bulk laxative may be necessary. Advice on anal hygiene is given. If this treatment fails, infrared coagulation or injection sclerotherapy is indicated. Second or second to third degree hemorrhoids should be treated with rubber band ligation from the very beginning. In view of their possible complications, both methods should be used only by trained and experienced physicians.

Combined Modality Therapy↗