Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Ear Neoplasms”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 343 records · Page 19Linked to original sources
PubMed1989

Neoplasia involving the middle ear cavity of dogs.

Eleven cases of neoplasia which involved the middle ear cavity of dogs are recorded. Eight of the tumours originated in the external ear canal and comprised four adnexal tumours, one squamous papilloma and three adenocarcinomas of the ceruminous glands. Papillary adenomas were recognised within the middle ear cavity of two dogs. In one animal the precise origin of an anaplastic carcinoma involving the middle ear could not be determined. Only five of the tumours were amendable to surgical excision and four dogs survived for more than eight months after surgery.

Adenocarcinoma↗
PubMed2001

Epidemiology of basal cell carcinoma and squamous cell carcinoma of the pinna.

This is a retrospective study designed to compare the incidence of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in the head and neck skin area with special reference to the pinna. The results showed 426 patients had 460 cutaneous malignancies in the head and neck area, managed by four specialties (ENT, Dermatology, General Surgery and GPs) over the period 1994-99. The lesions comprised 375 (80.47 per cent) BCC and 85 (18.47 per cent) SCC. In cases of BCC the facial areas were commonly involved (88 per cent), whilst SCC was almost equally distributed between the most (face, forehead and nose) and least exposed areas (pinna and scalp). The overall ratio of BCC to SCC remained four to one in the head and neck area. In 41 patients with 51 lesions over the pinna there were 29 (56.8 per cent) BCC and 22 (43.1 per cent) SCC hence the ratio was 1.3 to 1 for this site. We conclude that in the case of a suspicious lesion over the pinna, the risk of SCC is comparatively much higher. With increasing awareness of early and quick diagnosis of cancer cases, it is recommended that these patients should be referred urgently to prevent the significant morbidity associated with invasive SCC.

Aged↗
PubMed1982

Adenocarcinoma and adenoma of the middle ear.

Primary middle ear glandular tumors of the adenocarcinoma and adenoma types are rare. The terminology used in describing them is quite varied. Some investigators presume that a distinct recognizable group of these tumors are benign, but because of the rarity of the lesions, such conclusions have been difficult to verify. We review the literature of these lesions and report 11 additional cases. The course was documented in 25 cases in the literature; 20 of these were reported to be benign over periods of follow-up from 1 month to 10 years, and 5 were fatal. Among our patients, 5 had a benign course, 3 died of causes related to the tumor, and 3 had persistence of their lesion and substantial consequent morbidity. We emphasize the slow growth and elusive nature of these lesions. Histologic evidence of mitoses, roentgenologic evidence of bony destruction, and cranial nerve involvement were factors consistent with a poor prognosis. The origin of these tumors may vary. A similarity to paragangliomas is noted. The ultimate course of these tumors cannot always be predicted from the histologic appearance. Early surgical removal appears to be the most successful therapy. Three of the 4 types of glandular tumors of the external ear canal described by Wetli, et al, can be found in the middle ear: adenoma, adenocarcinoma, and adenoid cystic carcinoma. In addition, several other types of glandular lesions can occur in the middle ear--the "choristomas," mucoepidermoid carcinomas, and what we believe to be a variant of paragangliomas. The adenoid cystic tumors are well described in the literature and will not be discussed here. We reviewed cases of the adenoma and adenocarcinoma types, some of which bore a resemblance to the paragangliomas.

Adenocarcinoma↗
PubMed1983

Complications associated with the surgical treatment of cholesteatoma.

The surgical complications associated with a cholesteatoma are predictable preoperatively depending upon the location of a cholesteatoma. If the patient has an attic cholesteatoma the surgeon can anticipate postoperatively a dry ear, minimal chance of a persistent or recurrent cholesteatoma, a satisfactory hearing restoration, and, although a mastoidectomy is usually necessary, the size of the mastoid cavity in an adult can be extremely small. If a patient has a middle ear cholesteatoma the surgeon can anticipate postoperatively a relatively high incidence of moist ears, persistent or recurrent cholesteatoma, and an unsatisfactory hearing result. However, rarely will the creation of a mastoid cavity be necessary as rarely will mastoidectomy be required. Although most of the children "before puberty" in the study had middle ear cholesteatomas, all children, regardless of the location of cholesteatoma, had a higher incidence of surgical failure than did adults.

Cholesteatoma↗
PubMed2000

[Histopathological study of the temporal bones in patients with primary carcinomas of the ear].

The most common symptoms of patients with carcinomas of the middle ear or mastoid are otorrhea, facial paralysis, and hearing loss, including a sensorineural element and vertigo. The latter two symptoms are indicators of inner ear damage. However, few reports have been made concerning the histopathological changes that occur in the inner ear in the presence of a tumor. The present study was performed to determine the pattern of tumor invasion in the inner ear and the histopathological changes that occur in the inner ear in cases of ear carcinomas. Temporal bone sections from five patients (age: #39-73 years; 3 males and 2 females) who died from a primary carcinoma of the ear were studied histologically. The following features were examined: 1) localization of the tumor in the temporal bone, 2) pattern of tumor invasion in the inner ear, 3) pathological changes in the inner ear, including the cochlea, vestibule and semicircular canals. Tumor cells were still present in the temporal bone sections of all the patients except one, even though the patients had received various treatments for the carcinoma, including radiation therapy, surgery and chemotherapy. Marked inflammatory and necrotic changes were observed in cases where the tumor had invaded the external auditory canal, middle ear cleft, internal auditory canal, and in some cases the inner ear. In cases where the tumor invaded the inner ear via the internal auditory canal rather than directly from the middle ear, the otic capsule is thought to have acted as a barrier against tumor invasion. In addition, marked degenerative changes throughout the entire inner ear structures were noted. These changes may have arisen from an attenuated blood supply to the inner ear as a result of pressure from the tumor in the internal auditory canal, tumor infiltration of the labyrinthine artery.

Adult↗
PubMedDate not supplied

The auricular VX2 carcinoma--an animal model for sentinel node concept.

BACKGROUND: Considering the increasing clinical significance of the sentinel node (SN) concept, the applicability of the auricular VX2 carcinoma as an animal model for simulation of the SN concept was evaluated. MATERIALS AND METHODS: By means of blue dye and immunofluorescence-marked colloids, the lymphatic drainage of the auricle was described in 8 New Zealand white (NZW) rabbits. In 28 NZW rabbits, the extent of metastatic spread of auricular VX2 carcinomas after 8, 18, 21, 28 and 32 days of tumor growth was examined. RESULTS: Lymphogenic metastatic spread was limited to the parotideal lymph node functioning as SN for 21 days. The disintegration of the physiologic integrity of the SN leads to metastatic spread in the area of the secondary lymph node station after 28 days of tumor growth with successive hematogenic spreading. CONCLUSION: The auricular VX2 carcinoma in NZW rabbits is an appropriate animal model for simulation of the lymphogenic metastatic spread and the SN concept in HNSCC.

Animals↗
PubMed2006

[Malignant melanoma of the pinna. Importance of its diagnosis, treatment and prognostic factors].

About 25%-30% of the primary malignant melanomas occur in the head and neck region and of these less than 10% arise on the external ear, mainly on helix and the lobule of the pinna. Melanoma thickness and nodal or distant metastases are advers factors for its prognosis. We report a case of a tumor that affected the right pinna and was removed by our ENT, department with good evolution, being the patient free of disease after 5 years follow-up.

Aged↗
PubMed1991

[Small papular tumors of the perifollicular and perivascular connective tissue of the head and neck area].

The clinical picture of perifollicular benign tumors resemble that of juvenile warts, but the histopathology is completely different. Three different forms of perifollicular tumors, pure or mixed, have been observed. We report a fourth, previously unrecorded form, named perivascular fibroma from its histological appearance. The histological findings indicate a possible inflammatory etiology, as is also suggested by perifollicular fibroma, whereas postinflammatory signs are absent in trichodiscoma and fibrofolliculoma. The prognosis after removal of these tumors is favorable.

Adult↗