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At least 343 records · Page 19Linked to original sources

Assessment of a novel alternative to conventional formocresol-zinc oxide eugenol pulpotomy for the treatment of pulpally involved human primary teeth: diode laser-mineral trioxide aggregate pulpotomy.

OBJECTIVE: The purpose of this study was to investigate whether a diode laser pulpotomy with mineral trioxide aggregate (MTA) sealing could be an acceptable alternative to the conventional formocresol pulpotomy and zinc oxide eugenol (ZOE) sealing in human primary teeth. METHODS: A randomized, single-blind, split-mouth study was used with a sample of 16 children aged from 3 to 8 years (mean age=5.10 years). A total of 26 pairs of teeth from these 16 patients were selected based on clinical and radiographic criteria. One tooth from each pair was randomly assigned to either the laser-MTA pulpotomy group or the formocresol-ZOE pulpotomy group. All teeth were followed up clinically and radiographically at 2.3, 5.2, 9.5 and 15.7 months. All extracted failures were sectioned and photographed to assess possible reasons for this. RESULTS: A total of seven laser-MTA-treated teeth were deemed to be radiographic failures (mean time until failure=9.1 months) compared to three formocresol-ZOE treated teeth (mean time until failure=12.5 months). These results were not significant using Fisher's exact test (P>0.05). Six of the laser-MTA failures and all three formocresol-ZOE failures exhibited furcal and/or periapical radiolucencies with or without pathologic root resorption. One of the laser-MTA failures displayed premature root resorption and is being observed for exfoliation. Analysis of photographs of teeth available for extraction revealed errors in clinical technique in addition to expected signs of a disease process such as the presence of granulation tissue and areas of pathologic root resorption. CONCLUSIONS: The laser-MTA pulpotomy showed reduced radiographic success rates compared to the formocresol-ZOE pulpotomy at 15.7 months; however, these results were not statistically significant. Improved success rates among a larger patient sample and a longer follow-up period would be required for the laser-MTA pulpotomy to be considered a routine alternative to the conventional formocresol-ZOE procedure. Meticulous restorative techniques must be followed to ensure the success of laser-MTA pulpotomies.

Aluminum Compounds↗

Solubility of zinc oxide-eugenol and calcium hydroxide cements in simulated dentinal fluid.

The solubility of four dental cement bases was measured in simulated dentinal fluid and distilled water to evaluate the relevancy of the American Dental Association solubility test for cement bases in contact with vital dentine. A simulated dentinal fluid was formulated utilizing glucose, distilled water, and sterile human plasma. Cement-base samples were immersed in either distilled water or simulated dentinal fluid at 37 degrees C in a shaker water-bath for 1, 2, or 3 months. Weight loss values were compared utilizing a three-way analysis of variance. Zinc oxide-eugenol cements were significantly more soluble in simulated dentinal fluid than distilled water, while the calcium hydroxide cement bases were significantly more soluble in distilled water than simulated dentinal fluid.

Calcium Hydroxide↗

Allergy tests against formaldehyde, cresol, and eugenol in children with formocresol pulpotomized primary teeth.

One hundred and twenty-eight children in the age range 5-14 years with formocresol pulpotomized teeth were tested for sensitivity againist formaldehyde, eugenol, and cresol using the patch test. The number of treated teeth on each child varied from one to six and the time between the pulpotomy and patch test varied from 2 months to 8 years. None of the children showed positive results.

Adolescent↗

Effects of two gutta-percha formulations and one zinc oxide-eugenol and Canada balsam mixture on human blood monocytes and lymphocytes.

In this study we performed an in vitro assay of the effects of two gutta-percha formulations and one zinc oxide-eugenol and Canada balsam-based endodontic material on the behavior of a mixed cell population of human monocytes and lymphocytes. Cells were cultured either in direct contact with or near experimental samples of Ultrafil, standard gutta-percha cones or Endoseal and the inhibitory effects of these materials upon cell attachment and spreading on test surfaces were analyzed. Ultrafil and the standard gutta-percha cones showed little or no adverse effects, whereas the inhibitory effects of Endoseal appeared to be severe. There were statistically significant differences between the results obtained from both Ultrafil and gutta-percha cones and those obtained from Endoseal. Differences between all tested materials and their respective controls were also statistically significant.

Balsams↗

Influence of zinc oxide and eugenol sealer on concentration of zinc, calcium and copper in rat tissues.

A zinc oxide and eugenol root canal sealer (Roth 811) and sterile saline solution were injected into the dorsal thoracic midline of 70 male Wistar-Furth rats. Every day for the next 7 days, 10 animals were sacrificed by either inhalation. The liver, heart, kidneys and brain were removed from the animals and analysed for zinc, calcium and copper concentrations by flame atomic absorption spectrophotometry. The tissue around the injection site was also surgically removed and prepared for histological evaluation under a microscope. The injection of Roth 811 significantly affected the concentrations of zinc, calcium and copper in some of the examined organs, especially on the 4th and 5th day. The inflammatory reaction adjacent to the material was severe during the first 3 days while on the 7th day the presence of connective tissue with collagen formation was observed.

Animals↗

Examination of the test for compressive strength applied to zinc oxide eugenol cements.

The distribution of compressive strength results for a zinc oxide eugenol cement is negatively skewed. However, removal of a small number of outlying low results converts the distribution to a normal one. Crosshead speed and friction at the anvil have no significant effect on results, but compressive strength is a function of the diameter-length ratio of the cylinder and increases with this ratio.

Dental Stress Analysis↗

Clinical study of dental cements. VI. A study of zinc phosphate, EBA-reinforced zinc oxide eugenol and polyacrylic acid cements as luting agents in fixed prostheses.

A clinical trial for the final cementation of crowns and bridges with a reinforced zinc oxide and eugenol cement, a polyacrylic acid cement and a zinc phosphate cement was made over a 3-year period. The study involved 441 patients for whom 547 bridges and 162 single restorations were cemented. The patients were recalled at 6-month intervals for the duration of the study and the restorations were examined for looseness. Of the 547 bridges 520 remained firmly cemented to the abutment teeth. Of 1,082 bridge retainers, 1,049 remained in position; success and failure by types of retainer will be the subject of a subsequent paper. Of the 162 single restorations 159 remained in place.

Acrylates↗

Simultaneous determination of cinnamaldehyde, eugenol and paeonol in traditional Chinese medicinal preparations by capillary GC-FID.

A capillary GC method was established for simultaneous determination of cinnamaldehyde (CNMD), eugenol (EL) and paeonol (PL) in two traditional Chinese herbal medicinal preparations, Weitongding tablet (WTDT) and Guifu Dihuang pill (GDHP). The assays were based on a programmed temperature GC in a 30 m x 0.53 mm capillary column with nitrogen as carrier and FID detector. Good linearities were obtained over ranges of 0.45-452 mg/l CNMD, 0.31-625 mg/l EL and 0.30-610 mg/l PL, respectively. The spike recoveries were within 84-111%.

Acetophenones↗

Sensitive liquid chromatographic assay for the simultaneous determination of ibuprofen and its prodrug, ibuprofen eugenol ester, in rat plasma.

A rapid, sensitive, and specific reverse-phase high-performance liquid chromatography (HPLC) method was developed to quantitate ibuprofen (IBU) and its prodrug, ibuprofen eugenol ester (IEE), simultaneously in rat plasma. IBU, IEE, and the internal standard glycryrrhetic acid (GA) were detected by UV absorption at 230 nm. Extraction recoveries for all compounds ranged between 82.6% and 96.2%. Retention times of IBU, IEE, and GA were 5.62, 15.98, and 18.05 min, respectively. Calibration plots were linear over the range of 0.64 to 64 microg/ml for IBU, and 0.16 to 80 microg/ml for IEE. The limit of quantitation was 0.64 microg/ml for IBU and 0.16 microg/ml for IEE. The intra- and interday variations were less than 10% and accuracy was greater than 90%. The results showed that the established method is reproducible and sensitive and applicable to plasma samples collected from rats administered IBU and IEE intravenously.

Animals↗

In vitro activity of zinc oxide-eugenol and glass ionomer cements on Candida albicans.

The aim of this study was to evaluate in vitro the antimicrobial activity of glass ionomer (GIC) and zinc oxide-eugenol (ZOE) cements against Candida albicans. Standardized GIC and ZOE specimens were maintained in contact with C. albicans suspension (1 x 10(6) cells/ml) at 37 degrees C for 24 h, 48 h or 7 days. A control group without any testing cement was included. After the incubation period, aliquots of 0.1 ml were plated on Sabouraud's agar, and then the number of colonies was counted. The results were expressed as values of logarithms of colony-forming units per milliliter (log CFU/mL) and were analyzed statistically by Kruskal-Wallis ANOVA. After 48 h of incubation, the ZOE group presented no growth of C. albicans. GIC and control groups presented similar mean values at all tested periods. According to the results obtained, it could be concluded that, under the experimental conditions, ZOE cement was more effective in vitro against C. albicans than GIC.

Analysis of Variance↗

Weathering trials of Amulet cue-lure and Amulet methyl eugenol "attract-and-kill" stations with male melon flies and oriental fruit flies (Diptera: Tephritidae) in Hawaii.

Amulet C-L (cue-lure) and Amulet ME (methyl eugenol) molded paper fiber "attract-and-kill" dispensers containing fipronil were tested under Hawaiian weather conditions against Bactrocera cucurbitae (Coquillett) (melon fly) and Bactrocera dorsalis (Hendel) (oriental fruit fly), respectively. In paired tests (fresh versus weathered), C-L dispensers were effective for at least 77 d, whereas ME dispensers were effective for at least 21 d. Thus, C-L dispensers exceeded, whereas ME dispensers did not meet the label interval replacement recommendation of 60 d. Addition of 4 ml of ME to 56-d-old ME dispensers restored attraction and kill for an additional 21 d. This result suggested the fipronil added at manufacture was still effective. By enclosing and weathering ME dispensers inside small plastic bucket traps, longevity of ME dispensers was extended up to 56 d. Fipronil ME and C-L dispensers also were compared, inside bucket traps, to other toxicants: spinosad, naled, DDVP, malathion, and permethrin. Against B. dorsalis, fipronil ME dispensers compared favorably only up to 3 wk. Against B. cucurbitae, fipronil C-L dispensers compared favorably for at least 15 wk. Our results suggest that fipronil C-L dispensers can potentially be used in Hawaii; however, fipronil ME dispensers need to be modified or protected from the effects of weathering to extend longevity and meet label specifications. Nonetheless, Amulet C-L and ME dispensers are novel prepackaged formulations containing C-L or ME and fipronil that are more convenient and safer to handle than current liquid insecticide formulations used for areawide suppression of B. dorsalis and B. cucurbitae in Hawaii.

Animals↗

Lack of modifying effects of eugenol on development of lung proliferative lesions induced by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.

To investigate the modifying effects of eugenol (EUG), a component of cigarette smoke, on lung carcinogenesis, male and female transgenic mice carrying the human prototype c-Ha-ras gene (rasH2 mice) were given a single intraperitoneal injection of 250 mg/kg urethane (UR) or saline, followed by a diet containing 6,000 ppm EUG or basal diet for 26 weeks. Their non-transgenic CB6F1 littermates (non-Tg mice) were also treated in the same manner. In both male and female rasH2 mice, alveolar/bronchiolar hyperplasias, adenomas and carcinomas were observed in all UR-treated groups. However, there were no significant intergroup differences in the incidences and multiplicities of these lesions between the UR alone and UR + EUG groups. In non-Tg mice, alveolar/bronchiolar hyperplasias, adenomas or carcinomas were sporadically observed in UR-treated groups of both sexes, with no significant differences in the incidences and multiplicities between the UR alone and UR + EUG groups. There were no intergroup differences between them in the PCNA-positive ratios of adenomas or carcinomas and the areas of adenomas or carcinomas to the whole lung area examined. The present results suggest that the EUG treatment does not exert modifying effects on lung carcinogenesis induced by UR in both male and female rasH2 mice and non-Tg mice.

Adenoma↗

Effect of eugenol and tincture of crataegus (TCR) on in vitro oxidation of LDL + VLDL isolated from plasma of non-insulin dependent diabetic patients.

The present study was carried out to study the effect of antioxidants on oxidised LDL + VLDL and found that vitamin E, eugenol and tincture of crataegus (antioxidants) inhibited oxidation of (LDL + VLDL) similar to standard antioxidant (butylated hydroxy toluene). Vitamin C acted as an antioxidant at lower concentration, and prooxidant at higher concentration.

Antioxidants↗

The influence of gross caries removal and temporary filling of dental caries with a zinc oxide eugenol cement on the level of mutans streptococci in saliva.

The influence of gross caries removal and temporary filling of dental caries with a zinc oxide eugenol cement on the salivary level of mutans streptococci (MS) was studied in 14 children, 6 to 8 years of age. Forty-eight hours after filling all cavities, there was a significant decrease in the level of these cariogenic microorganisms. However, after 30 days, the salivary level of mutans streptococci was similar to that detected initially.

Child↗

[Influence of eugenol-containing temporary cement on efficacy of dentin-bonding systems].

OBJECTIVE: This study investigated the influence of eugenol-containing temporary cement on the efficacy of two relatively new dentin-bonding systems. METHODS: Thirty-two freshly extracted bovine central incisors were randomly divided into four groups. Dentin was exposed and polished with 320#, 400#, and 600# sand papers. After embedded, Group 3 and 4 specimens were covered with ZOE. Specimens in Group 1 and 2 were served as control. All specimens were stored for 1 week in distilled water at 37 degrees C. Then, the ZOE was mechanically removed. The dentin surfaces of Group 1 and 3 were treated with Prime & Bond NT bonding system and the dentin surfaces of Group 2 and 4 were treated with GLUMA adhesive system according to manufacturer's instructions. Thereafter composite resin columns (6 mm diameter, 2 mm high) were applied. After specimens stored in distilled water at 37 degrees C for 24 hours, the shear bond testing was carried out using a SHIMADZU universal testing machine with a cross-head speed of 0.5 mm/minute. The mode of failure was examined using SEM. The data were analyzed using ANOVA test at a significance level of 0.05. RESULTS: The medians of shear bond strength for each group were as follows: Group 1 (Prime & Bond NT) 9.57 MPa, Group 3 (Prime & Bond NT + ZOE) 10.72 MPa, Group 2 (GLUMA) 16.89 MPa, Group 4 (GLUMA + ZOE) 16.78 MPa. Group 1 and 3 had significantly lower bonding strength than did Groups 2 and 4. But no significant difference was found between the control groups and the groups treated with ZOE temporary cement. CONCLUSION: Pretreatment of the dentin with ZOE temporary cement has no adverse influence on the efficacy of two relatively new dentin-bonding systems.

Animals↗

A comparison of two methods for removing zinc oxide-eugenol provisional cement.

Two methods of removing zinc oxide-eugenol (ZOE) luting cement from amalgam were compared by determining their effect on the tensile bond strength of amalgam cylinders luted together using a 4-META resin cement. The samples were examined using scanning electron microscopy and energy dispersive x-ray analysis. Results showed that mechanical cleansing with pumice leaves ZOE residue mixed with pumice, which inhibits bonding, while the bond strength of samples cleansed with a dental degreasing agent was similar to that of an uncontaminated control group.

Acrylic Resins↗