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At least 343 records · Page 19Linked to original sources

[Transcutaneous cerebral electric stimulation by Limoge current during labor].

In order to test the analgesic efficacy of Anesthelec (transcutaneous cranial electrical stimulation with Limoge currents) during labour and delivery, a double blind study was performed in 20 cases for whom analgesia was necessary. In 10 cases Anesthelec was used with the Limoge currents on and in 10 cases as a sham. Labour and delivery were carried out by a medical team different from that which set up the Anesthelec. The results showed that this method, with or without nitrous oxide inhalation, decreased by 80% the number of epidural and general anaesthesias that would otherwise have been unavoidable. To define the effects of this new method, maternal and foetal parameters of 50 deliveries carried out under Anesthelec were compared with 50 deliveries carried out under epidural analgesia. Anesthelec was used only if analgesia was required. This study was a retrospective comparison between two similar non paired series. Despite the fact that analgesia obtained with Anesthelec was less powerful than with epidural analgesia, this method showed many advantages: total safety for the child and the mother, easy utilization, shorter labour time, decreased number of instrumental extractions and potentially reduced costs. Good acceptance and satisfaction for the mother should allow a rapid evolution of this new method.

Adult↗

[Electro-drug anesthesia. Clinical and hormonal effects of transcranial electrostimulation].

The French technique of anaesthesia by electrostimulation described in 1972 by Cara and coworkers, consists of transcranial electrostimulation by means of a high frequency current combined with administration of a neuroleptic drug, a benzodiazepine, a curare and nitrous oxide with oxygen. Fentanyl is also given by some authors. In order to assess the benefit of such electrostimulation, this study compared two randomized groups of ten patients, scheduled for abdominal and pelvic surgery. Both groups received the same drugs (i.e. droperidol, flunitrazepam, pancuronium and nitrous oxide with oxygen), whereas patients in group I were also submitted to electrostimulation. This study describes and discusses the clinical behaviour of patients and the hormonal reactions before, during and after surgery. In both groups, operative conditions were satisfactory. Recovery and onset of spontaneous ventilation were rapid and no patient had an unpleasant recall of the operation itself. However, most of them complained of postoperative pain. Electrostimulation did not reduce the quantity of drugs required during and after surgery. In both groups, circulatory activity was significantly increased. In group I, the arterial pressure and the heart rate were significantly higher than in group II during and after surgery. The hormonal reactions showed that in both groups adrenocorticotrophic hormone, growth hormone and antidiuretic hormone increased during surgery. Adrenocorticotrophic hormone concentration was higher in group I during the operation. The serum levels of cortisol decreased before surgery in group I and rose in both groups during and after laparotomy; prolactin increased before surgery.(ABSTRACT TRUNCATED AT 250 WORDS)

Adrenocorticotropic Hormone↗

Electroanaesthesia or electroimmobilisation of calves, sheep and pigs by the Feenix Stockstill.

Since the end of the last century many investigations with electroanaesthesia have been performed in animals and man. The interest in this method of anaesthesia has emerged because anaesthesia is achieved immediately after the onset of the current and the recovery is very rapid after cutting off of the current. Recently a battery operated apparatus became available (Feenix Stockstill) for application of electroanaesthesia and electroimmobilisation under field conditions, and an experiment was conducted with 10 calves, 10 sheep, and 9 pigs, which were equipped with EEG and ECG electrodes, to check the analgesic and other practical effects of the apparatus. The duration of current administration was 20 minutes. Three animals of each species were used as control animals. In all animals, during administration of the current, the breathing movements appeared to be somewhat impaired. The rectal body temperature, the plasma cortisol level, and the pulse rate were raised during the current administration. Moreover, the pulse rate was irregular. The corneal reflex remained positive in all animals, and the reaction to painful stimuli was positive in 15 out of 29 experimental animals. The rectal body temperature, pulse rate, and plasma cortisol level remained constant in the control animals. Before and after administration of the current the electroencephalogram recordings were similar, except in one calf and one sheep, both of which showed patterns suggesting a decreased consciousness. The electrocardiogram recordings showed pronounced changes in cardiac activity. In one pig the heart activity stopped some minutes after the onset of the current. Changes in the electroencephalogram and electrocardiogram were not observed in the control animals during their treatment.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Improvement of postoperative analgesia during cancer surgery with Limoge's current: a personal experience.

BACKGROUND: The anesthesiologist took advantage of a personal experience to determine whether transcutaneous cranial electrical stimulation using Limoge's current (TCES-LC) improved the level of postoperative analgesia by potentiating anesthetic agents used during the intra- and postoperative phases. Included were analgesics injected through an epidural thoracic catheter (T8-T9) positioned at the end of an esophagectomy. Another reason for a self-experimentation was to be able to evaluate the psycholeptic effects of TCES-LC to gain a better understanding of the problems linked with pain during treatment. METHODS: The Limoge' current is bidirectional and consists of a high-frequency biphasic asymmetrical wave composed of modulated, high-frequency (166-kHz) pulse trains with a repetition cycle of 100 Hz. TCES-LC was initiated 2 hours before anesthetic induction without any tranquilizer or other medication. TCES-LC was continuously applied during the entire surgical procedure and continued 48 hours postoperatively in the intensive care unit (ICU). As the objective was not to obtain electrical anesthesia, the usual anesthetic protocol was used during surgery. RESULTS: During the initial 48 postoperative hours with continuous application of TCES-LC (D0-D1), a decrease of the epidural anesthetic dose requirement was observed for ropivacaine, and sufentanil (-25% and -60% respectively). A similar decrease in these medications was also measured on day 2 (D2), while TCESLC was terminated. This decrease was amplified day 3 (D3) for both ropivacaine and sufentanil (-50% and -73% respectively). On day 4 (D4) the epidural anesthetics were totally suppressed (1 day before the normal conventional schedule planned for by the ICU physician with this type surgery). CONCLUSION: Future clinical trials need to be conducted to show the significant advantages of TCES-LC in alternative and complementary medicine.

Aged↗

The use of direct current to cause selective block of large fibres in peripheral nerves.

The effect of direct current on the propagated compound action potential in a cutaneous branch of the radial nerve of the dog was studied and a convenient method for applying electrical current to a nerve is described. Changes in the flow of blocking current, even when these were made slowly during a period of 5-10 sec, caused stimulation of the nerve. The method was satisfactory for producing differential nerve block within the myelinated fibres. It was confirmed that direct current could be used to eliminate selectively the group II/III potentials. When these potentials had been eliminated for a period of 5 min the mean height of the group IV potentials was reduced to 65% of the control value, and their conduction velocity was decreased by 10%. Relatively small variations in current flow caused a marked change in conduction. In the early stages of block, frequent relatively large reductions in current flow were necessary to produce a constant response and it was impossible to cause a stable effect on conduction until the blocking current had been applied for at least 1 min. Because of nerve damage the method is unsuitable for clinical use.

Action Potentials↗

Intracranial stimulation for the control of chronic pain.

Long-term stimulation of deep brain structures for pain relief has been efficacious in a significant number of patients who have been total failures at every other means of pain control. Two primary sites are used at this time--the periventricular grey area, which is related to the endogenous opiate system, and the internal capsule system, which is related to the dorsal column projection system. Periventricular sites are more efficacious for externally generated pain, that is, pain with input through the dorsal horn. Internal capsule stimulation is more efficacious for central nervous system-generated pain. While the preoperative preparation and intraoperative testing as well as postoperative testing of these patients requires a great deal of time and tedious attention to detail, our long-term results have been excellent using a combined comprehensive pain unit approach to pain and stress management, plus the stimulation techniques in carefully selected patients. Our results would indicate that initially 80-85% of patients get good pain relief, and then that range decreases to between 50 and 60% over a long period of time. Deep brain stimulation for pain relief is not a technique that should be used on a large number of patients with simple pain problems, but is highly efficacious in a selected group of patients with very specific pain problems that do not respond to usual pain treatment techniques. In patients with pain generated by benign etiologies, it is far superior to destructive procedures and does not have the secondary side effects of sensory loss, postchordotomy dysesthesias, or secondary neurological deficits.(ABSTRACT TRUNCATED AT 250 WORDS)

Brain↗

Electrical stunning, hot boning, and quality of chicken breast meat.

The first experiment was conducted to determine the effects of varying voltage, 20, 40, 80, and 100 V at 60 Hz, on stunning efficiency, blood loss, and carcass defects. In the second experiment, the same parameters were evaluated to determine the effects of varying frequency, 60, 200, 350, 500, and 1,000 Hz at 40 V. A control group for both experiments was not stunned. At 40V, 30 to 50 mA, 90% of the birds were unconscious, as shown by no response to comb piercing, and blood loss was maximized (55.3%). When varying the stunning frequency, maximum blood loss (73.1%), 90% of the birds were unconscious, and minimum carcass defects were observed at 1,000 Hz, 40 V. In the third experiment, birds were stunned at 40 V, 1,000 Hz and deboned immediately after defeathering (hot boning) and chilled or deboned after passing through all stages of a commercial abattoir operation (conventional boning). Control lots were unstunned and followed normal abattoir stages. Average shear value was significantly lower for stunned compared to unstunned birds (6.0 vs. 7.1 kg/g), although tenderness scores, as measured by a trained panel, were not significantly different (6.6 for stunned birds vs. 6.1 for unstunned). Scores for juiciness were also not significantly different (5.5 for stunned vs. 5.8 for unstunned). Average shear value was also significantly lower for conventionally boned birds (5.2 kg/g) than for hot boned birds (7.9 kg/g). Sensory analysis confirmed the shear value results. Conventionally boned breasts had an average tenderness score of 7.4 vs. an average of 5.3 for hot boned breast. No statistical differences were observed with respect to juiciness, although a score of 6.2 was observed for conventionally boned breast meat vs. a score of 5.1 for hot boned breast meat.

Abattoirs↗

Transcutaneous cranial electrical stimulation (Limoge's currents) decreases early buprenorphine analgesic requirements after abdominal surgery.

Transcutaneous cranial electrical stimulation with Limoge's currents (TCES) consists of high frequency, low intensity currents which decreased anesthetic requirements during elective surgery. This action is likely to be mediated by the release of central endogenous opioids. In the present study, we hypothesized that TCES applied intraoperatively may decrease early postoperative narcotic requirements. Thirty-nine ASA physical status I and II patients undergoing elective abdominal surgery were enrolled in this prospective, randomized, double-blind, placebo-controlled study. Just before induction of anesthesia, patients were connected to the electrical stimulator and randomly allocated to be either stimulated (TCES group, n = 20) or not (control group, n = 19) during surgery. The managing anesthesiologist was unaware of which group the patient was assigned. Postoperatively, patients were given a patient-controlled analgesia (PCA) device delivering buprenorphine for the first four postoperative hours. The recorded variables included postoperative buprenorphine requirements, pain scores (0-10 visual analog scale [VAS]), sedation (0-4 scale), and intraoperative isoflurane requirements. Patients were comparable with respect to age, sex ratio, weight, duration of surgery, intraoperative hemodynamics, fentanyl requirements, and time from skin closure to tracheal extubation. Buprenorphine requirements were significantly reduced in the TCES group versus the control group (2.36 vs 3.43 micrograms.kg-1.h-1; P = 0.002). Intraoperative isoflurane anesthetic requirements, as well as hourly postoperative scores for pain and sedation, were the same for the two groups. These data indicate that TCES reduces narcotic requirements for early postoperative analgesia. This technique might have potential to facilitate early postoperative analgesia in patients undergoing elective abdominal surgery.

Abdomen↗