Sodium cyclamate, saccharin and food efficiency.
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Animal Feed↗
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Results for “Cyclamates”
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Myocardial lesions: a reassessment of the toxicology of calcium cyclamate.
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Animals↗
Hyperactivity in rats bred and raised on relatively low amounts of cyclamates.
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Animal Feed↗
Determination of cyclamates in soft drinks.
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Beverages↗
Determination of cyclamate in soft drinks by gas chromatography.
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Beverages↗
The determination of cyclamate in soft drinks by titration with sodium nitrate.
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Beverages↗
The determination of cyclohexylamine in cyclamates.
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Cyclohexanes↗
Lipophilic derivatives of cyclam as new inhibitors of tumor cell growth.
Two new lipophilic tetraazamacrocycles were prepared and, in contrast to non-lipophilic analogs, found to be potent inhibitors of tumor cell growth in vitro with IC50 values below 10 micromolar.
Animals↗
Cyclam (1,4,8,11-tetraazacyclotetradecane) with one methylphosphonate pendant arm: a new ligand for selective copper(ii) binding.
The new ligand, [(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]phosphonic acid (H(2)te1P, H(2)L), was synthesized and its complexing properties towards selected metal ions were studied potentiometrically. The ligand forms a very stable complex with copper(ii)(logbeta(CuL)= 27.34), with a high selectivity over binding of other metal ions (i.e. logbeta(ZnL)= 21.03). The crystal structures of the free ligand (in its protonated form with bromide as counter-ion) and two copper(ii) complexes (obtained by crystallization at various pH) were determined. The free ligand adopts the common conformation for such macrocycles with the protonated nitrogen atoms in the corners of a virtual rectangle. In the trans-Br,O-[Cu(Br)(Hte1P)].H(2)O species, the central metal ion is surrounded by four in plane nitrogen atoms, one oxygen atom of the pendant moiety in the apical position and a bromide anion positioned trans to the oxygen atom, forming a distorted octahedral coordination sphere. In the compound [Cu(H(2)te1P)][Cu(Hte1P)]Br(3).6H(2)O, obtained from a highly acidic solution, the bromide anions are placed further away from the copper(ii) ion and the coordination environment (N(4)O) is thus square-pyramidal. In both structures, the protons are associated with non-coordinated phosphonate oxygen atoms.
Journal Article↗
Gut bacteria and the metabolism of cyclamate in the rat.
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Animals↗
Growth inhibitory action of saccharin and cyclamate on rats receiving a poor rice diet.
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Animals↗
Letters to the editor: effect of sodium cyclamate on protein-bound iodine.
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Animals↗
Copper(I) and copper(II) complexes of an ethylene cross-bridged cyclam
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Journal Article↗
Cyclamates and human cells.
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Body Weight↗