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A new library for emergency medicine.

The publication of textbooks that are relevant to emergency medicine has increased rapidly during the past decade. This increase has created confusion in the selection of appropriate texts for both emergency medicine residency and hospital emergency department libraries. A critical review of 703 pre-selected texts was performed. From this review, a recommended list of 165 books for the resident library and 27 books for the emergency department library is suggested. The cost of these libraries is $6,433.05 and $1,230.05, respectively. The libraries are designed to assist emergency physicians and librarians in attaining maximum value in the expensive process of textbook selection.

Bibliographies as Topic↗

Evaluation of monograph selection in a health sciences library.

This article reports on an evaluation of recent monograph selections in a small academic health sciences library. Actual use of each new book was determined from date-due slips. Data were analyzed by broad subject, discipline, and number of uses. The startling result was that more than 60% of recent selections had been used little or not at all. To determine factors affecting use, the author examined aggregate data, used intuition, and assessed the raw data in more detail. Recommendations made to management were approved and implemented. The study bolstered confidence that it is possible to select materials with the highest potential for use and to depend on remote access for other needed works. It is suggested that other health sciences libraries undertake such studies and question the need to strive for comprehensive collections.

Book Selection↗

Physician-patient interaction in reproductive counseling.

OBJECTIVE: To review the scientific and clinical bases for effective patient counseling in contraceptive care. DATA SOURCES: All articles and chapters in the Annotated Bibliography of Doctor Patient Communication of the Task Force on Doctor and Patient of the American Academy on Physician and Patient were searched and included. This is an expert-derived data base based on MEDLINE review from 1969 to 1994 and including expert-selected additions from PsychLit and a variety of other social science data bases, books, and reviews. METHODS OF STUDY SELECTION: Expert consensus was used from the Committee on Bibliography of the American Academy on Physician and Patient. TABULATION, INTEGRATION, AND RESULTS: The doctor-patient interaction is the main determinant of the accuracy and completeness of patient data, diagnostic accuracy, efficiency in the encounter, compliance, patient understanding of problems, and patient and physician satisfaction. Yet this critical skill is inadequately taught and practiced, with serious consequences for patient care and physician job satisfaction. Use of the 14 structural elements (preparing the environment, preparing oneself, observation, greeting, introduction, detecting and overcoming barriers to communication, surveying problems, negotiating a priority problem, developing a narrative thread, establishing the life context of the patient, establishing a safety net, presenting findings and options, negotiating plans, and closing) and three functions (gathering information, developing a therapeutic relationship, and patient education) and their associated behaviors improves encounter results significantly. Other helpful activities are patient activation, facilitating partnership, review of findings and plans, eliciting and responding to patients' attitudes and emotions about contraception and fertility, and use of empathy and positive regard. CONCLUSIONS: The use of scientifically derived, empirically validated interview skills substantially improves outcomes in contraceptive and other patient education and counseling. Use of appropriate structure and functions of the encounter, patient participation and partnership, review of patient understanding and reactions, and relating to the patients' attitudes and emotions about the subject each improve the outcomes of contraceptive care.

Contraception↗

Mondino de' Liuzzi and his Anothomia: a milestone in the development of modern anatomy.

Mondino's Anothomia was written in Bologna around 1316. This book is the intellectual legacy of one of the fathers of human anatomy, and probably represents a collection of lessons given by the author at the Studium in Bologna. Mondino's Anothomia witnesses a profound renewal of the mode of understanding and teaching human anatomy through direct observation of dissected corpses. This book enjoyed an extraordinarily large dissemination in the whole of Europe, thanks to many extant manuscripts and printed editions. In this article, we present some selected passages from this remarkable book to let today's anatomists know how great was the descriptive skill of this medieval scientist, a pioneer in the anatomical discipline.

Anatomy↗

Communication problems associated with cleft palate and related disorders. Annotated bibliography.

The books in this annotated bibliography were selected because of the general nature of the information that they provide. Most of these books contain bibliographies that include references of a more technical nature should the reader desire such information. These books are available at most university libraries. Additional information can be obtained from brochures and fact sheets published by the Cleft Palate Foundation (1218 Grandview Avenue, Pittsburgh, PA 15211). These publications were prepared primarily for patients and parents, but can provide useful information to professionals who typically do not work with patients with cleft palate and craniofacial anomalies.

Child↗

Neural edelmanism.

The recent book Neural Darwinism (ND) by Gerald Edelman, claims to put forward 'a radically new view of the function of the brain and nervous system'. Its main focus is on the understanding of the biological basis of perception. This new view is based on what Edelman calls 'The Theory of Neuronal Group Selection', the subtitle of his book. In spite of Edelman's lengthy and spirited account of this new theory, most readers appear to have had some difficulty in grasping his ideas and many have complained that the book is not easy to read. It has been particularly difficult to relate Edelman's ideas to those already current and well-known, especially as Edelman himself says rather little on this topic. In this critique I aim to set out Edelman's central ideas, as they appear to me, in a clearer and more digestible form. I examine both his general exposition of these ideas and the simulations he has presented to support them, giving page references so that the concerned reader can check my statements against the text. I have considered also Edelman's original papers, upon which the book is based, but I have not considered more recent papers which deal with matters (such as Darwin III) that are not covered in the book.

Animals↗

The major achievements of biological products in China.

PURPOSE: To review the major achievements of biological products of China in the scientific research and development. DATA SOURCES: The contents of this article were selected from the original essays or reviews related to biologicals published in Chinese and foreign journals. STUDY SELECTIONS: Briefly original articles and reviews of text books published by Chinese authors in the last twenty years were selected. DATA EXTRACTION: These data have addressed the novel vaccines and engineering genetic technologies on biologicals. RESULTS: Nowadays about 200 kinds of biological products are produced in China ranging from preventive vaccines as the majority to therapeutic and diagnostic products. About 800-900 million doses of vaccines for the purpose of prophylaxis are administered annually. Biologicals have played an important role in the prevention of infectious diseases. During the former 30 years the basis for the further development of research work was set up and in the latter 20 years new achievements were made one after another, for example, the development of attenuated JE vaccine, hepatitis A live vaccine, HFRS inactivated vaccine, recombinant HB vaccine and Vi typhoid vaccine, et al. CONCLUSION: During the past 50 years, China has made a great progress in the field of biological products, however we are still week in the aspect of basis research and backward behind the developed countries in originating new products.

Biological Products↗

Brazilian plants with possible action on the central nervous system: a study of historical sources from the 16th to 19th century.

Brazil is a country rich in biodiversity, endemism, and cultural diversity, inhabited by different types of population. European expeditions and the migratory processes that began in the 16th century greatly contributed both to cultural diversity and to Brazilian popular therapeutics, and produced the first records on medicinal plants in Brazil. This study comprises a bibliographical survey of historic books found in Sao Paulo libraries (16th through 19th centuries) on medicinal plants exerting effects on the central nervous system (CNS). Thirty-four plants native to Brazil were selected from the reading of the books. Of these 34 plants, 13 were also recorded in ethnopharmacological studies among modern Brazilian communities and 16 have been studied phytochemically. Only eight have been the object of pharmacological studies, six of these, recently, with a request for a patent. Results showed that most of the species recorded in this study have been reported as medicinal for centuries, but have never been the object of pharmacological investigation down to the present time. Such results provide ideas for a selection of these species as potentially bioactive to be included in future pharmacological studies.

Books↗

[Problem of sexuality in Polish medical aids. The first half of XX century - to 1939].

The article presents an analysis of sexuality-related problems as they are covered in the health guidebooks so well known to her. There are a few topics addressed in Urbanek's text. She describes the evolution of the health guidebooks which was taking place at the end of the 19th and in early 20th centuries and of their users. Women increasingly often were authors and readers of these books. Some of the female authors were medical doctors with an additional passion for writing on public matters. Foreign authors and their works are also mentioned in Urbanek's article. She points to the links between sexology and personal hygiene and even cosmetology. Sexology is present in the guidebooks discussed also as an important ingredient of successful marriage. In this context, Urbanek stresses the changing role of a woman and her strife for acquiring equal rights. Another valuable element in the article is reference to other spheres of culture, such as custom and religion. The 20th century filled these spheres with medical knowledge on childbirth pathologies and their complications. Medical and hygiene-related topics motivate Urbanek to set the question of sexuality in a context of eugenic ideas often debated in the pre-war years. She also points to the multicultural character of the Polish-language health books, identifies various angles of view presented in them, and supports her reflection with well-selected examples. This applies eg. to Soviet books. Although this is not her main subject, Urbanek also writes about health books dealing with sexual matters and destined for men. The author of the article gives a fine description of the variability of sexuality-related contents carried by these books which offered adequate coverage of changes occurring in medical, hygienic, cultural, and even economic fields. The paper is, therefore, not only an analysis of sexuality-related issues but it also presents a broad social context in which these books were conceived and written.

History, 20th Century↗

A retrospective evaluation of the surgical management of equine carpal injury.

Records of 220 thoroughbred horses presented to the Randwick Equine Centre or the University of Queensland Veterinary Teaching Hospital for surgical management of carpal injury were reviewed. Details of racing performance were obtained, enabling evaluation of racing success following surgery. Age and sex matched control horses not known to have suffered carpal injury were selected from the Australian Stud Book and the Australian Racehorse Register. Control and treated populations were compared in terms of overall career racing success. Radiographs or xeroradiographs from 198 horses were available for evaluation. The dorsomedial aspects of the distal articular surface of the radial carpal bone and the proximal articular surface of the third carpal bone were the most commonly observed locations of osteochondral fracture. Bilateral carpal injury was found to be sufficiently common to warrant routine radiographic examination of both limbs. The dorsolareral-palmaromedial oblique, flexed lateral and dorsoproximal-dorsodistal oblique (skyline) projections were the most useful views for evaluation of carpal degenerative joint disease. Surgical removal of osteochondral fractures by arthrotomy or arthroscopy was found to be a suitable method of treatment. Arthroscopy was associated with a significantly shorter convalescent period than arthrotomy. Seventy-six percent of the treated population returned to racing following surgery. Average earnings following surgery were $20,000. However, the median value was only $1400 and 48% of the treated population failed to earn more than $1000. Male horses in both the treated and control groups performed significantly better than females. Treated horses performed significantly better than the randomly selected control population.

Animals↗

Drug product selection: legal issues.

OBJECTIVE: To review the potential legal liability of the pharmacist in the drug product selection process. DATA SOURCES: Published articles identified through MEDLINE, published law reviews identified through InfoTrac, and appellate court decisions. Search terms used included pharmacist liability, drug product selection, and generic substitution. Additional articles, books, and appellate court decisions were identified from the bibliographies of retrieved articles and citations in appellate court decisions. DATA SYNTHESIS: Pharmacists engaging in drug product selection are civilly liable under three legal theories: negligence, express or implied warranties, and strict product liability. Potential criminal liability includes prosecution for insurance fraud, deceptive business practices, and violation of state drug product selection laws and regulation. CONCLUSION: Pharmacists increase their liability when engaging in drug product selection, but the increase is small. Still, the law continues to evolve as pharmacists seek expanded roles and responsibilities. When courts give closer examination to pharmacists' expanded role, it is likely that pharmacists' liability will increase.

Drugs, Generic↗

An historical analysis of disclosure of terminal status.

PURPOSE: To examine the concept of disclosure of terminal status and trace its development and implementation over time. An individual's ability to make appropriate end-of-life decisions, exert some control over the place and manner of death, and prepare self and significant others for this loss depends on knowing that life is drawing to a close. ORGANIZING FRAMEWORK: An analysis of disclosure of terminal status was performed within the context of American social, political, and cultural history from 1930 to 1990. METHODS: A combination of manual and computerized search mechanisms was performed utilizing popular, nursing, medical, sociological, psychological, and thanatological literature from 1930 to 1990. The articles and books obtained through these searches were scanned and those articles and books that dealt with health care disclosure issues were selected. Works included in the review were 149 articles and 22 books. FINDINGS: A long-standing tradition of nondisclosure exists in the medical profession. Societal events in the 1950s and 1960s influenced individuals' perceptions of death, individual rights, and physician responsibility, and culminated in some change in this tradition in the 1970s. The magnitude of this change is unknown. Current practice has not been investigated. This topic is rarely addressed in nursing literature even though nursing care is influenced by physicians' practice. CONCLUSIONS: A tradition of nondisclosure prohibits patients from managing the end of their lives and making choices about their manner of death. Nursing care of terminally ill patients is compromised when patients are uninformed.

Attitude to Death↗

Prevalence and predictors of depressive symptoms in older premenopausal women: the Harvard Study of Moods and Cycles.

BACKGROUND: The Harvard Study of Moods and Cycles is a community-based cohort study designed to evaluate the relationship between major depression and changes in menstrual and ovarian function. METHODS: All women aged 36 to 44 years with a verifiable address from 7 Boston, Mass, metropolitan communities were selected from the Massachusetts Town Books. A self-administered questionnaire assessed demographic characteristics and menstrual history, depression history, and current depressive symptoms (Center for Epidemiologic Studies Depression Scale [CES-D]) in 4161 women. RESULTS: We observed a score of 16 or more on the CES-D in 22.4% of women surveyed, and 8.6% scored 25 or more. Widowed, divorced, or separated women were twice as likely as married women to have depression scores greater than 16 (95% confidence interval, 1.6-2.8), and smokers in the upper tertile of pack-years were 1.9 times more likely to have CES-D scores of 16 or more (95% confidence interval, 1.5-2.3). Relative to nulliparous women, those with 1 or 2 children had a 30% lower risk of historic mood disorder, and those with 3 or more children had an even greater reduction in risk (odds ratio, 0.4; 95% confidence interval, 0.3-0.6). Menstrual cycle irregularities were largely unassociated with current or past depression. However, 5 of 8 premenstrual symptoms were significantly associated with CES-D scores of 16 or more. CONCLUSIONS: These findings corroborate the prevalence of depression reported by other community-based studies, and also support a relationship between depressive symptoms and marital status, cigarette smoking, nulliparity, and premenstrual symptoms.

Adult↗

Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies.

CONTEXT: There are many published twin studies of schizophrenia. Although these studies have been reviewed previously, to our knowledge, no review has provided quantitative summary estimates of the impact of genes and environment on liability to schizophrenia that also accounted for the different ascertainment strategies used. OBJECTIVE: To calculate meta-analytic estimates of heritability in liability and shared and individual-specific environmental effects from the pooled twin data. DATA SOURCES: We used a structured literature search to identify all published twin studies of schizophrenia, including MEDLINE, dissertation, and books-in-print searches. STUDY SELECTION: Of the 14 identified studies, 12 met the minimal inclusion criteria of systematic ascertainment. DATA SYNTHESIS: By using a multigroup twin model, we found evidence for substantial additive genetic effects-the point estimate of heritability in liability to schizophrenia was 81% (95% confidence interval, 73%-90%). Notably, there was consistent evidence across these studies for common or shared environmental influences on liability to schizophrenia-joint estimate, 11% (95% confidence interval, 3%-19%). CONCLUSIONS: Despite evidence of heterogeneity across studies, these meta-analytic results from 12 published twin studies of schizophrenia are consistent with a view of schizophrenia as a complex trait that results from genetic and environmental etiological influences. These results are broadly informative in that they provide no information about the specific identity of these etiological influences, but they do provide a component of a unifying empirical basis supporting the rationality of searches for underlying genetic and common environmental etiological factors.

Diseases in Twins↗

Event-related fMRI reveals cortical sites involved in contextual sentence integration.

We examined the effects of difficulty of sentential integration on blood oxygenation level-dependent contrast changes. Difficulty of integration was operationalized as the degree to which sentence-final nouns matched the expectations generated by preceding context. Nine young adults read short sentence fragments (e.g., "The pilot flies.") which were completed by highly expected nouns (e.g., "the plane"), unexpected yet semantically legal nouns (e.g., "the kite"), nouns that violated the verbs' selection restriction rules (e.g., "the book"), and pseudowords (e.g., "the foop") and made quick lexical decisions on the sentence-final item. Overall, word completions resulted in higher changes in activation than pseudoword completions. The largest of those changes were observed in left angular and posterior middle temporal gyri, suggesting that despite the lexical nature of the task, word stimuli embedded in sentence contexts triggered integrative-semantic processes beyond a lexical level. A region-of-interest analysis in left inferior frontal and left posterior middle temporal areas revealed activation for both unexpected and anomalous completions when compared to expected completions. Thus, while the underlying processing mechanisms may differ, sentential integration appears similarly effortful for these two types of completions. Our findings are consistent with previous reports of local increases in activation as a function of (syntactic) complexity, while extending the findings to processing demands of semantic integration. Because of its sensitivity to changes in semantic congruence and the implicit nature of the task involved, we argue that the present paradigm is well suited to study patients with potential semantic deficits after brain damage.

Adult↗

The influence of social class on health status: American and British research on health inequalities.

PURPOSE: To summarize recent and past American and British studies on the relationship of social class and health status. DATA SOURCES: A systematic review of the pertinent British and American literature, including references identified from bibliographies of books and recent articles. STUDY SELECTION: Published English-language studies that report original or summary data describing socioeconomic status and mortality/morbidity are emphasized. DATA SYNTHESIS: Social class, whether measured by occupation, income, or education, has a marked effect on mortality and morbidity. Use of British and American standardized mortality ratios (SMRs) shows that the gap between the advantaged upper socioeconomic classes and the disadvantaged lower classes has become wider from 1930 to 1980. Explanations for this inequality in health status by socioeconomic status point to four factors: artefact, social selection, culture/behavior, and material/structural conditions. A synthesis of existing literature suggests that material deprivation and social deprivation are the most important factors contributing to this association, although data from longitudinal studies implicate social hierarchy. CONCLUSION: The reviewed studies point to growing inequalities in health status between those of lower and those of higher socioeconomic status. Clinicians and teachers in internal medicine should incorporate this knowledge in assessing patients and adopt a perspective that takes account of socioeconomic factors in diagnostic and management decisions.

Female↗

Overnight intensive recovery: elective open aortic surgery without a routine ICU bed.

OBJECTIVES: Most patients are managed on the intensive care unit (ICU) after elective open aortic surgery. We preoperatively identify patients suitable for extubation in theatre with overnight management in theatre recovery before discharge back to the ward (overnight intensive recovery (OIR)). The safety of this was investigated. DESIGN: Retrospective case note analysis of all patients who underwent EOAS from 1998 to 2002, recording in-hospital morbidity and mortality. Physiological and operative severity score for the enUmeration of mortality and morbidity (POSSUM) data were collected prospectively. METHODS: Patients were divided into those selected for OIR and those booked for elective ICU admission. Observed morbidity and mortality data were compared with predicted outcomes generated by Portsmouth-POSSUM and POSSUM equations. RESULTS: Hundred and fifty-two out of 178 patients used OIR; 155 patients had abdominal aortic aneurysm (AAA) repair. The elective ICU group had significantly higher anaesthetic risk scores (ASA grade), larger AAA, greater intraoperative blood loss and longer operations. In the OIR group, ten patients (7%) needed ICU admission within 48h postoperatively. Complications occurred in 85/152, with two deaths. There was no excess morbidity or mortality in the OIR group (predicted 95% CI 83-105 and 5-17, respectively). CONCLUSION: Most patients having elective open aortic surgery can be managed safely using OIR.

Aged↗

Current concepts of fetal growth restriction: part II. Diagnosis and management.

OBJECTIVE: To update diagnostic concepts and management strategies of fetal growth restriction (FGR). DATA SOURCE: An English literature search was conducted for pertinent articles related to FGR from 1976 to 1997 including original research articles, review articles, and book chapters. METHODS OF STUDY SELECTION: In part II, clinical studies involving both diagnostic and therapeutic approaches to the management of FGR were included. Throughout the study period, the evolution of concepts is demonstrated. TABULATION, INTEGRATION, AND RESULTS: Diagnostic methods including two- and three-dimensional ultrasound for diagnosis of fetal structural abnormalities, organ volumetry, and estimating fetal weight are presented. Clinical tools to assess fetal well-being such as nonstress tests, contraction stress tests, biophysical profile scores, and Doppler blood flow velocimetry of fetal circulation and funicentesis are discussed. Correlations between these indirect fetal evaluations and fetal blood biochemical parameters obtained by funicentesis are also reviewed. Finally, various therapeutic approaches, especially timing of delivery of growth-restricted fetuses, are formulated. CONCLUSION: We suggest that both diagnostic and therapeutic approaches to FGR should be modified. With the current development of technology, newly available three-dimensional ultrasound might offer more precise diagnostic data than conventional two-dimensional ultrasonography in the near future. From current concepts of pathophysiology of FGR, morphometric measurement abnormality alone should not be a basis for intervention. Combined use of morphometric measurements and functional evaluation tests and good clinical judgment using flexibility and individualization are the key elements in successful management of FGR.

Fetal Growth Retardation↗