The state of the art of biomedical engineering in the operative-endoscopic treatment of gastrointestinal bleedings.
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Much of the bioinstrumentation in the early U.S. aerospace program in the 1950's was undertaken by the U.S. Air Force, first at Randolph Field, TX, and then at Brooks AFB, TX. We document here some of the equipment and some of the experiences encountered by the early experimenters. This period coincided with the introduction of solid-state circuitry into biomedical instrumentation and also strongly influenced research into the electrochemical interface between metal electrodes and the ionic body environment. The author recalls much of his own early work, as well as his recollections of some of the other early researchers.
The major steps of advancement in electrocardiology over a period exceeding one century of its existence are briefly summarized, and some considerations concerning the most promising trends of its current and future progress are presented. (Tab. 2, Fig. 2, Ref. 39.)
As defined by the National Institutes of Health (NIH), bioengineering is an interdisciplinary field that applies physical, chemical, and mathematical sciences and engineering principles to the study of biology, medicine, behavior, and health. It advances knowledge from the molecular to the organ systems level, and develops new and novel biologics, materials, processes, implants, devices, and informational approaches for the prevention, diagnosis, and treatment of disease for patient rehabilitation and for improving health.
To validate clinically a new stereotactic device for real-time monitored minimally-invasive brain surgery; to perform the first European phase I clinical trials of Boron Neutron Capture Therapy (BNCT) for treatment of glioblastoma, using the facility of the Community Joint Research Centre (JRC) in Petten, on forty patients from six different European centres. These are typical objectives of the current EC BIOMED 2 demonstration projects. The number of supported projects under BIOMED is now 16 in 1998, and will be in total around 80 for the three Life Sciences and Technologies Programmes. Demonstration is expected to play a major role in the Fifth Framework Programme, particularly in its so-called "Key Actions". This article addresses three of the main issues for potential applicants: the readiness for demonstration, the content of the consortium, and the dissemination strategy.
A systems approach to health care inevitably emphasizes shifting present emphasis from curative to preventive orientations. However, problems arise through the inertia and resistance of our politico-cultural system. The present highly-developed curative-oriented system depends heavily on technological and biomedial engineering expertise, as indeed will a preventive-oriented system. They must serve however within the priorities defined by the systems objectives in health care. This paper reviews, in terms of technological content and socio-political issues, some major developments including; multiphasic health testing and disease screening, health appraisals, clinical labs and other test procedures, protocols, computerized information systems, data bases and systems modelling.