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Effectiveness of assistance circulations for distal circulatory support during cross-clamping of the descending thoracic aorta.

In order to find the ideal distal circulatory support during cross-clamping of the descending thoracic aorta, the author compared the effects of simple shunting (SS) and centrifugal pump (CP) on hemodynamics and metabolisms in mongrel dogs. In group I (control), the aorta was cross-clamped for two hours without SS or CP; in group II (SS), a temporary shunt was placed between the left common carotid and left femoral arteries during cross-clamping; in group III (CP), with left heart bypass, the flow was maintained about the same as that in group II; in group IV (CP), proximal pressure was maintained unchanged. Hemodynamic and metabolic parameters were recorded prior to cross-clamping and every 30 min for four hours during and after cross-clamping. All animals in group I suffered from hemodynamic instability, metabolic abnormalities and neurologic injury and died within 12 hours. Hemodynamic changes were more unstable in group III than in groups II and IV. Three dogs in group III and also in group IV but none in group II, suffered from neurologic injury. Metabolic changes in groups II, III and IV were not significant. The author conclude that hemodynamic and metabolic abnormalities can be minimized through the efficient use of a shunt in cross-clamping of the descending thoracic aorta and postoperative complications such as paraplegia, renal failure and hepatic dysfunction can be prevented. The centrifugal pump as a distal circulatory support device is able to maintain stable hemodynamics and normal distal organic metabolisms if aortic pressure proximal to the clamp is maintained essentially unchanged through regulation of pump flow. However, it is unable to prevent paraplegia during cross-clamping of the descending thoracic aorta for two hours. Shortening the time of cross-clamping of the descending thoracic aorta is necessary to prevent paraplegia.

Animals↗

[Assisted circulation to the right ventricle through pulmonary counterpulsation using a biological method].

PURPOSE: To study the hemodynamic effects of latissimus dorsi dynamic pulmonaroplasty in open chest animals. METHODS: Six anesthetized mongrel dogs were subjected to diastolic counterpulsation using electrically stimulated latissimus dorsi muscle flap wrapped around the aortic and pulmonary arteries roots and gated to the surface electrocardiogram. Aortic and Pulmonanary pressures as well as cardiac output and cardiac index were measured. RESULTS: Diastolic counterpulsation resulted in a significant increase in cardiac output (from 2.35 +/- 0.26 to 2.45 +/- 0.28 l/min) (p < 0.005) and cardiac index (from 0.108 +/- 0.020 to 0.113 +/- 0.020 l/min/kg) (p < 0.05). The diastolic pulmonary arterial efficiency index showed a significant increase when latissimus dorsi stimulation was on (from 8.37 +/- 0.60 to 11.65 +/- 0.83 mmHg); (p < 0.005). CONCLUSION: Latissimus dorsi dynamic pulmonaroplasty provides an effective means of arterial counter pulsation in open chest dogs.

Animals↗

[Operational control of the effectiveness of assisted blood circulation].

Introduction into the clinical practice of methods providing for mechanic support to the heart demands equipping the apparatus of assisted circulation with appliances, helping to operatively assess the effect of applying some or other procedures helping the heart performance. The existing criteria do not allow the degree of restoring the contractility of the myocardium under the effect of assisted circulation to be appraised. Criteria may be of help in comparing the energy balance of the myocardium with application of assisted circulation and the energy balance of an unloaded myocardium are proposed.

Assisted Circulation↗

[Assisted blood circulation, efferent detoxication and hyperbaric oxygenation in the treatment of exotoxic shock].

Experimental and clinical data on the employment of assisted circulation with extracorporeal oxygenation of the blood, exchange replacement of the blood in high volumes, hemoperfusion, and hyperbaric therapy in the treatment of exotoxic shock caused by methemoglobin-forming and corrosive poisons demonstrate a high efficacy of assisted circulation in the normalization of central hemodynamics (which permits exchange replacement of the blood and hemoperfusion), of the hepatorenal function, hemostasis, and other parameters of the internal media in humans and animals. The method is recommended for wide use at large reanimation and toxicological centers.

Adult↗

[Noninvasive assisted blood circulation].

The experience of the use of noninvasive assisted circulation in patients with cardiac pathology is summarized. It has been demonstrated that rhythmic pneumo-compression of the lower extremities, abdominal compression, muscular electrical stimulation of the lower extremities and the abdomen have a pronounced effect on circulation compartments with low pressure. All the above pre-determines the role of these techniques in the management of cardiac failure and in intensive care.

Abdomen↗