[Effect of cortisone in a case of adrenogenital syndrome; temporarily favorable action].
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Adrenal Cortex↗
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Results for “ADRENOGENITAL SYNDROME”
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Congenital adrenal hyperplasia associated with the adrenogenital syndrome: an attempt to correct its disordered hormonal pattern.
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Adrenal Glands↗
[Isosexual adrenogenital syndrome with adrenal cortex hyperplasia in an adult male].
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Adrenal Cortex↗
[Modifications of personality in a case of adrenogenital syndrome (hetero-sexual precocious puberty) after removal of virilizing tumor].
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Adrenal Cortex↗
[Adrenogenital syndrome in child treated surgically].
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Adrenal Cortex↗
Adrenogenital syndrome with insufficiency of the electrolyte-regulating function of the adrenal cortex.
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Adrenal Cortex↗
[Genital findings in the female pseudo-hermaphroditism of the congenital adrenogenital syndrome; morphology, frequency, development and heredity of the different genital forms].
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46, XX Disorders of Sex Development↗
[Two surgical cases of metabolic adrenogenital syndrome, with infiltrating carcinoma in one case and adenomatous hyperplasia nodosa of the adrenal glands in the other].
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Adrenal Gland Neoplasms↗
Cortisone treatment of the adrenogenital syndrome with special reference to steroid excretion during continued and discontinued therapy.
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Adrenal Cortex↗
[A case of adrenogenital syndrome with presence of sympathicotropic cells in the ovarian hilus].
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Adrenal Cortex↗
[Adrenogenital syndrome caused by adrenal carcinoma].
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Adrenal Cortex↗
The adrenogenital syndrome in children a clinical and steroid metabolic study.
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Adrenal Cortex↗
The adrenogenital syndrome; discussion of a case with special reference to the paternal and maternal steroid patterns.
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Adrenal Cortex↗
[Diagnosis and therapy of the adrenogenital syndrome in women, with a case report on female pseudohermaphroditism in congenital adrenocortical hyperplasia].
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46, XX Disorders of Sex Development↗
Adrenogenital syndrome in a male child due to adrenocortical tumor; report of case with hemihypertrophy and subsequent development of embryoma (Wilms' tumor).
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Adrenal Cortex↗
[Adrenogenital syndrome in an adult woman caused by a benign adrenal tumor with the presence of urinary gonadotropins, very high elimination of 17-ketosteroids and positive response of 17-hydroxycorticoids to ACTH].
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17-Hydroxycorticosteroids↗
The effects of adrenocorticotropic hormone and cortisone in the adrenogenital syndrome associated with congenital adrenal hyperplasia: an attempt to explain and correct its disordered hormonal pattern.
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Adrenal Glands↗
[Diagnosis of the adrenogenital syndrome caused by 11beta-hydroxylase deficiency using gas chromatographic-mass spectrometric analysis of the urinary steroid profile].
PROBLEM AND OBJECTIVE: In 5-7% of all cases of congenital adrenogenital hyperplasia (AGH) there is 11 beta-hydroxylase deficiency (11 beta-HM). Its clinical picture is characterised by hyperandrogenism and, in some cases, arterial hypertension. The diagnosis of the enzyme deficiency depends on a reliable method of analysing the hormone in plasma and urine. As little is known and data often contradictory about the pattern of urinary steroid excretion in 11 beta-HM, these steroid metabolites were measured by a highly specific method. PATIENT AND METHOD: The pattern of urinary excretion of steroids was determined by gas chromatography and mass spectrometry (GC/MS) in 16 children and adults (11 males, 5 females: mean age 9(8)/12 [2/12-20(3)/12] years) with 11 beta-HM. RESULTS: In all patients there was greatly increased excretion of tetrahydrated (TH) and hexahydrated (HH) metabolites of 11-desoxycortisol (S) and desoxycorticosterone (DOC). The excretion of THS and THDOC was extremely increased in all patients. The metabolites 5 alpha-THS as well as 20 alpha- and 20 beta-isomers of HHS, not normal found in healthy persons, were present in 15 patients (94%), while the 20 alpha- and 20 beta-isomers of 5 alpha-HHS were demonstrated in 14 (88%). For the first time, 20 alpha- and 20 beta-isomers of 5 alpha-HHS were shown to be typical urinary steroid metabolites in 11-HM. The excretion of cortisol metabolites is typically decreased in 11 beta-HM. No corticosterone metabolites were found. CONCLUSION: The urinary steroid excretion pattern, measured by GC/MS, is a noninvasive, highly specific and nonselective method in the differential diagnosis of abnormal steroid metabolism.
Adolescent↗