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PubMed2001

The MetaFam Server: a comprehensive protein family resource.

MetaFam is a comprehensive relational database of protein family information. This web-accessible resource integrates data from several primary sequence and secondary protein family databases. By pooling together the information from these disparate sources, MetaFam is able to provide the most complete protein family sets available. Users are able to explore the interrelationships among these primary and secondary databases using a powerful graphical visualization tool, MetaFamView. Additionally, users can identify corresponding sequence entries among the sequence databases, obtain a quick summary of corresponding families (and their sequence members) among the family databases, and even attempt to classify their own unassigned sequences. Hypertext links to the appropriate source databases are provided at every level of navigation. Global family database statistics and information are also provided. Public access to the data is available at http://metafam.ahc.umn.edu/.

Computational Biology↗
PubMed2006

The contribution of Acadia PRIMENet research to science and resource management in the National Park Service.

Acadia National Park was one of the 14 sites included in the Park Research and Intensive Monitoring of Ecosystems network (PRIMENet). For eight years the EPA monitored ultraviolet (UV) radiation at this site, with the National Park Service (NPS) sponsoring a total climate and air monitoring station. Under the auspices of PRIMENet, research projects were initiated that investigated the effects of UV on amphibians, determined watershed mass balances, and developed a model of deposition along an elevational gradient. The monitoring data and research results have been used by park management to protect vegetation and water resources from ozone and deposition. These data are now being used to develop a "vital signs" monitoring program under the NPS' Inventory and Monitoring Program. These data sets have been used in regional, national and international programs to protect human health and resources from air pollution. Public outreach has been accomplished through web site resources and via the Schoodic Education and Research Center.

Air Pollution↗
PubMed2003

ACTIS and ATIS: new resources for AIDS information, part two.

The HIV/AIDS Treatment Information Service (ATIS) is a Web-based resource for federally approved treatment guidelines for HIV and AIDS. ATIS and ACTIS (AIDS Clinical Trials Information Service) are managed by the National Library of Medicine. Background information, search hints, and a content description of ATIS are provided.

Acquired Immunodeficiency Syndrome↗
PubMed1998

Meeting the challenge of finding resources for ophthalmic nurses on the World Wide Web.

The World Wide Web ("the Web") is a macrocosm of resources that can be overwhelming. Often the sheer volume of material available causes one to give up in despair before finding information of any use. The Web is such a popular resource that it cannot be ignored. Two of the biggest challenges to finding good information on the Web are knowing where to start and judging whether the information gathered is pertinent and credible. This article addresses these two challenges and introduces the reader to a variety of ophthalmology and vision science resources on the World Wide Web.

Databases, Factual↗
PubMed2000

PhysioNet: a research resource for studies of complex physiologic and biomedical signals.

PhysioNet (http://www.physionet.org/) is a web-based resource supplying well-characterized physiologic signals and related open-source software to the biomedical research community. Inaugurated in September 1999 under the auspices of the NIH's National Center for Research Resources (NCRR), PhysioNet provides an on-line forum for free dissemination and exchange of research data and software, with facilities for cooperative analysis of data and evaluation of new analytic methods. As of September 2000, PhysioBank, the data archive made available via PhysioNet, contained roughly 35 gigabytes of recorded signals and annotations. PhysioNet is a public service of the Research Resource for Complex Physiologic Signals, a cooperative project initiated by researchers at Boston's Beth Israel Deaconess Medical Center/Harvard Medical School, Boston University, McGill University, and MIT.

Cardiovascular Physiological Phenomena↗
PubMed2001

The Internet, the electronic medical record, the pediatric intensive care unit, and everything.

This article details how computers have changed life for those of us in pediatric intensive care. A week of clinical activity is described, with a focus on the interactions with computer systems that have become an integral part of patient-care activities for many of us. It becomes clear that the boundaries between personal computers, hospital systems, and the Internet are often not sharply defined. Resources that are used every week may include those residing on a personal digital assistant, on the hospital's electronic medical record, or on a distant site on the World Wide Web. Key resources on the Internet (World Wide Web and e-mail) are identified. The technical underpinnings, particularly the network that provides the infrastructure for various resources, are described.

Child↗
PubMed2001

Evidence-based nursing Web sites: finding the best resources.

Evidence-based nursing is becoming an increasingly widespread phenomenon in the nursing profession. As the evidence-based nursing movement grows, the Internet/World Wide Web has become a vital information link for keeping pace with current science and medical advancements. This article describes Internet resources currently available to support evidence-based nursing practice, presents practical search methods for locating these resources, and suggests criteria for evaluating the "evidence" available on the Internet. Results of an Internet search for Web sites that met the proposed criteria for support of an evidence-based nursing practice located only three sites. The sites are described and evaluated for their usefulness. The authors demonstrate that although many Internet resources are available to nurses, few sites provide information or evidence supported by valid research.

Evidence-Based Medicine↗
PubMed2006

Immunoinformatics comes of age.

With the burgeoning immunological data in the scientific literature, scientists must increasingly rely on Internet resources to inform and enhance their work. Here we provide a brief overview of the adaptive immune response and summaries of immunoinformatics resources, emphasizing those with Web interfaces. These resources include searchable databases of epitopes and immune-related molecules, and analysis tools for T cell and B cell epitope prediction, vaccine design, and protein structure comparisons. There is an agreeable synergy between the growing collections in immune-related databases and the growing sophistication of analysis software; the databases provide the foundation for developing predictive computational tools, which in turn enable more rapid identification of immune responses to populate the databases. Collectively, these resources contribute to improved understanding of immune responses and escape, and evolution of pathogens under immune pressure. The public health implications are vast, including designing vaccines, understanding autoimmune diseases, and defining the correlates of immune protection.

Amino Acid Sequence↗
PubMed1999

Mr Lewis on the Web--how to convert learning resources for intranet technology.

OBJECTIVES: Intranet technology is the application of Internet tools in local networks. Due to the diversification of hardware and the need for international cooperation, cross-platform systems with network access are required for computer-based training (CBT). The latest advances in Web technology make it feasible to have interactive CBT on the Web: Web-based training (WBT). It is possible to convert existing interactive learning programs to Intranet technology. This approach combines the evaluated contents of excellent learning resources with the technical advantages of Web technology. DESIGN: 'Mr Lewis' is a case about pulmonary embolism, developed by Harold Sox, M.D., working with one of the authors, and peer-reviewed at Dartmouth Medical School (DMS), where it is now being used in the third-year clerkship in Internal Medicine as one of several CBT programs assigned to students in the clerkship. RESULTS: The process and the tools necessary to convert an interactive learning program to Intranet technology are described. CONCLUSIONS: International cooperation for CBT development is much more effective with this technique than with conventional platform-dependent stand-alone software. Web-based training can play an important role in the education of medical students and doctors.

Clinical Clerkship↗
PubMedDate not supplied

Public health education and practice using geographic information system technology.

The use of geographic information system (GIS) technology allows public health practitioners to explore disparities in health, analyze disease outbreaks, and prioritize the use of limited resources for improving population health. Nursing students benefit from use of World Wide Web GIS resources as they develop knowledge and skill in assessing population health and planning interventions. This article identifies the benefits of GIS for public health practitioners, presents a communicable disease control application of GIS, and discusses a GIS module used in an undergraduate nursing education course. Uniform standards for making health data available for public use with GIS are discussed.

Diffusion of Innovation↗
PubMed1998

An insight into rheumatology resources available on the World Wide Web.

The aim of this study was to gain an overview of rheumatology resources on the World Wide Web (WWW). A list of websites was generated using a commercial search engine and 'rheumatology' as a key word. A total of 154 websites were then evaluated with respect to origin and likely target audience; 43% of this initial group were either not accessible, repeats, or in a language other than English. Of the 87 websites we were able to analyse, we found that 67% originated from medical organizations and 51% were interpreted to be directed specifically at rheumatologists. Only 16% of websites were directed at patients only. The remainder were felt to contain information useful to both groups. Over half the websites felt to be of interest to patients contained advertisements. Although there is a lot of information relating to rheumatology on the WWW, it was invariably time consuming to access and there was little directed solely at patient education.

Advertising↗
PubMed2000

An introduction to minority health resources on the World Wide Web.

Health care professionals and consumers often need information about, or targeted to, non-White or non-English speaking populations. Minority health resources sponsored by a variety of organizations are increasingly being made available on the World Wide Web. This information is easily accessible to providers, patients, and families, and community service agencies. The heterogeneity of sponsors, ranging from federal agencies to consumer advocacy and support groups- and their agendas-results in differences of quality, depth of content, and suitability for different information seekers. Taking a conservative approach, this article presents a collection of starting points whose roots are in established agencies, institutions, and organizations already familiar to most health care information professionals.

Health Education↗
PubMed1997

Consumer Versus Resource Control in Freshwater Pelagic Food Webs

Models predict that food-web structure is regulated by both consumers and resources, and the strength of this control is dependent on trophic position and food-web length. To test these hypotheses, a meta-analysis was conducted of 11 fish (consumer)-by-nutrient (resource) factorial plankton community experiments. As predicted, zooplankton biomass was under strong consumer control but was weakly stimulated by nutrient additions; phytoplankton biomass was under strong resource control with moderate control by fish. However, the phytoplankton and zooplankton responses to nutrient additions did not follow theoretical predictions based on the number of trophic levels in the food web.

Journal Article↗
PubMed2005

Caring Connection: developing an Internet resource for family caregivers of children with cancer.

This poster will describe the development of a family-focused, web-based resource, the "Caring Connection", designed to provide individualized clinical information, patient-centered information resources, and access to online family-provider and family-to-family communication for caregivers of children with cancer. Data from structured interviews with family caregivers and healthcare providers describe their current Internet use and information needs. Website prototype development and user testing provide additional insights that are informing the ongoing design of the "Caring Connection" website.

Caregivers↗
PubMed2003

Linking information on the World Wide Web.

The uniform resource locator (URL) is the key element of the World Wide Web, connecting widely separate sources of information. Logically constructed URLs are important in helping users find desired information. URLs can deceive users. Cyber squatting and other practices that manipulate URLs often lead the user to unwanted information. Critical to future scholarship and education is access to full text articles online. This will require consistent and well-constructed URLs.

Humans↗
PubMedDate not supplied

Internet resources for end-of-life care.

Numerous publications highlight the need for critically evaluating medical information on the Internet. This review identifies Internet resources specifically dedicated to end-of-life care. An annotated review of key web-based resources is presented. The Internet has the potential to catalyze the doctor-patient relationship toward true "partnership." Physicians and patients will benefit from using a focused research strategy.

Computer User Training↗
PubMedDate not supplied

Nursing education resources on the World Wide Web.

The Internet offers the promise of quick and convenient access to large amounts of up-to-date information. There are many resources on the Internet for nurses and nurse educators, but they can be challenging to locate and the information must be evaluated carefully. In this article, some nursing resources on the Internet are analyzed and criteria for evaluating information are suggested. With a little patience and persistence, nurse educators will find exploring the Internet rewarding and informative.

Computer Communication Networks↗